Patents
Patents for C07D 217 - Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems (11,865)
01/2002
01/01/2002CA1341330C Substituted acyl dertivatives of 1,2,3,4-tetrahydroisquinoline-3-carboxylic acids
12/2001
12/27/2001WO2001098264A1 Macrophage scavenger receptor antagonists
12/27/2001WO2001098256A1 Thyroid receptor ligands, pharmaceutical compositions comprising them and their use in the treatment of disorders influenced by thyroid hormones
12/27/2001WO2001098251A1 Novel substituted nitrocatechols, their use in the treatment of some central and peripheral nervous system disorders and pharmaceutical compositions containing them
12/27/2001US20010056100 Carboxylic acid or tetrazole derivatives containing carbamate groups are useful for treating the conditions associated with the urinary tract, pain, inflammation, respiratory states, edema formation of hypotensive vascular diseases
12/27/2001US20010056099 Method of reducing morbidity and the risk of mortality
12/25/2001US6333416 Chemical intermediate for protease inhibitor
12/25/2001US6333337 Potassium channel inhibitors
12/25/2001CA2068590C Process and intermediates for the preparation of spiro¬isoquinoline-4(1h),3'-pyrrolidine|-1,2',3,5'(2h)-tetrones which are useful as aldose reductase inhibitors
12/21/2001CA2351129A1 Novel substituted nitrocatechols, their use in the treatment of some central and peripheral nervous system disorders and pharmaceutical compositions containing them
12/20/2001WO2001087838A8 Cyclohexane derivatives and their use as therapeutic agents
12/19/2001EP1163225A1 Compounds and methods for modulation of estrogen receptors
12/19/2001EP1163213A1 Hydroxamic and carboxylic acid derivatives
12/19/2001CN1076345C 2,3-diaminopropionic acid derivatives
12/18/2001US6331640 Diaminopropionic acid derivatives
12/18/2001US6331630 Dimeric arylisoquinoline alkaloids and derivatives thereof
12/13/2001WO2001094359A1 Chiral ligands for asymmetric catalysis
12/13/2001US20010051633 E.g.,N-((4-amino-3-nitrophenoxy)ethyl)-1,2,3,4-tetrahydro -isoquinoline; stroke; antiischemic agents; CNS trauma, hyperglycemic agents; surgery; neurodegenerative diseases including Alzheimer's disease, amyotrophic lateral sclerosis
12/13/2001CA2410410A1 Chiral ligands for asymmetric catalysis
12/12/2001EP0781126B1 Derivatives of 2-amino-1,2,3,4-tetrahydro-naphthalene active on the cardiovascular system
12/12/2001EP0778827B1 Process for producing a beta-amino alcohol
12/11/2001US6329377 Enzyme inhibitors for nervous system disorders
12/06/2001WO2001092258A1 Imidazoloisoquinolines
12/06/2001WO2001092233A1 3-substituted isoquinolin-1-yl derivatives
12/06/2001WO2001092228A2 Process for the synthesis of amine ethers from secondary amino oxides
12/06/2001WO2001092212A1 Excitatory amino acid receptor modulators
12/06/2001WO2001091754A1 Protein kinase inhibitors
12/06/2001US20010049374 Amidino derivatives of quinoline and naphthalene
12/06/2001CA2410640A1 3-substituted isoquinolin-1-yl derivatives
12/06/2001CA2409597A1 Protein kinase inhibitors
12/05/2001EP1159264A2 INHIBITORS OF FACTOR Xa
12/05/2001EP1159258A1 Amide compounds for the potentiation of cholinergic activity
12/04/2001US6326398 Oxamic acids and derivatives as thyroid receptor ligands
12/04/2001US6326393 Glycol and hydroxyphosphonate peptidomimetics as inhibitors of aspartyl proteases
11/2001
11/29/2001WO2001090074A2 BENZOPHENONES AS INHIBITORS OF IL-1β AND TNF-$g(a)
11/29/2001WO2001090070A2 Caspase inhibitors and uses thereof
11/29/2001CA2408727A1 Benzophenones as inhibitors of il-1.beta. and tnf-.alpha.
11/29/2001CA2380935A1 Caspase inhibitors and uses thereof
11/28/2001EP1157001A1 Oxamic acids and derivatives as thyroid receptor ligands
11/28/2001CN1075490C O-benzyl oxime ether derivatives and their use in crop production compositions
11/27/2001US6323367 Reacting tertiary or secondary amine with hydrogen peroxide as an oxidant in presence of a recyclable heterogeneous layered double hydroxide exchanged with transition metal oxides as a catalyst in an organic solven, stirring, filtration
11/27/2001US6323215 Treat and prevent disorders characterized by neuronal damage such as parkinson's disease, alzheimer's disease, stroke, multiple sclerosis, amyotrophic lateral sclerosis, diabetic neuropathy and bell's palsy.
11/27/2001US6323201 Compounds for inhibition of ceramide-mediated signal transduction
11/22/2001WO2001087883A1 Hydroxamic and carboxylic acid derivatives having mmp and tnf inhibitory activity
11/22/2001WO2001087866A1 Cyclohexyl derivatives and their use as therapeutic agents
11/22/2001WO2001087845A2 N-containing heterocyclic compounds and their use as 5-ht antagonists
11/22/2001WO2001087844A1 Hydroxamic and carboxylic acid derivatives having mmp and tnf inhibitory activity
11/22/2001WO2001087843A1 Compounds for treating disorders where a decreased level of plasma ffa is desired
11/22/2001WO2001087838A1 Cyclohexane derivatives and their use as therapeutic agents
11/22/2001DE10023484A1 New 2-((cycloalkyl- or heterocyclyl-alkyl)-amino)-benzamide derivatives, are VEGF receptor, KDR kinase and FLT kinase inhibitors useful e.g. for treating tumors, psoriasis, arthritis or renal or ophthalmological diseases
11/22/2001CA2410077A1 Cyclohexyl derivatives and their use as therapeutic agents
11/22/2001CA2408849A1 Cyclohexane derivatives and their use as therapeutic agents
11/21/2001EP1155304A2 A system for cell-based screening
11/21/2001EP1155001A1 Isoquinoline derivatives and isoquinoline combinatorial libraries
11/21/2001CN1323291A Diaminopropionic acid derivatives
11/21/2001CN1075062C 乙酸衍生物 Acetic acid derivatives
11/20/2001US6319925 O-benzyl oxime ether derivatives and their use in crop protection compositions
11/15/2001WO2001085721A1 N-sulfonyl hydroxamic acid derivatives as inhibitors of cd 23
11/15/2001WO2001085695A1 Tetrahydroisoquinoline analogs useful as growth hormone secretagogues
11/15/2001WO2001085694A2 Substituted diamide derivatives useful as motilin antagonists
11/15/2001WO2001085693A1 N-acyltetrahydroisoquinoline derivatives
11/15/2001WO2001085675A2 Fluorous tagging compounds and their use
11/15/2001WO2001085671A2 Anthranyl amides and their use as medicaments
11/15/2001WO2001085170A1 Peptide deformylase inhibitors
11/15/2001WO2000071507A3 INHIBITORS OF FACTOR Xa
11/15/2001WO2000050872A9 A system for cell-based screening
11/15/2001US20010041718 Cis-6-(4-fluoro-phenyl)-5-(4-(2-piperidin-1-yl-ethoxy)-phenyl) -5,6,7,8-tetrahydronaphthalene-2-ol, for example, and other estrogen agonists/antagonists to treat rheumatoid arthritis, colon cancer, wounds, cataracts and skin wrinkles
11/15/2001US20010041714 Serotonin-7 (5-HT7); treatment of central nervous system disorders such as sleep disorders, depression and schizophrenia; for example 1,3-dihydro-2-((4-(4-fluorophenyl)-4-oxobutyl))isoindole
11/15/2001CA2408486A1 Tetrahydroisoquinoline analogs useful as growth hormone secretagogues
11/15/2001CA2408343A1 N-acyltetrahydroisoquinoline derivatives
11/15/2001CA2408288A1 Novel substituted diamine derivatives useful as motilin antagonists
11/15/2001CA2408236A1 Peptide deformylase inhibitors
11/15/2001CA2408095A1 Fluorous tagging compounds and their use
11/15/2001CA2407817A1 Anthranilamides and their use as pharmaceutical agents
11/14/2001CN1322193A Unsaturated hydroximic acid derivatives as PARP inhibitors
11/13/2001US6316638 Conformationally constrained amino acid compounds having affinity for the alpha2delta subunit of a calcium channel
11/13/2001US6316625 Methods of making HIV-protease inhibitors and intermediates for making HIV-protease inhibitors
11/13/2001US6316617 For treating physiological disorders associated with an excess of neuropeptide y, such as feeding disorders and certain cardiovascular diseases, medical diagnosis
11/13/2001US6316450 Compounds
11/13/2001US6316415 Sulfonamide interleukin-1β converting enzyme inhibitors
11/13/2001US6316214 ETM-775 metabolite of ecteinascidin 743
11/08/2001WO2001083445A1 Biphenyl butyric acid derivative as a matrix metalloproteinase inhibitor
11/08/2001WO2001083427A1 PPARη MODULATORS
11/08/2001US20010039348 Alpha-methylbenzyl-containing thiourea inhibitors of herpes viruses containing a phenylenediamine group
11/08/2001US20010039285 Tetrahydroisoquinoline compounds as estrogen agonists/antagonists
11/08/2001CA2407587A1 Ppar.gamma. modulators
11/08/2001CA2377629A1 Biphenyl butyric acid derivative as a matrix metalloproteinase inhibitor
11/07/2001EP1151998A1 Estrogen agonists/antagonists
11/07/2001EP1150948A1 ALKENYL AND ALKYNYL COMPOUNDS AS INHIBITORS OF FACTOR Xa
11/07/2001CN1321140A Transfer hydrogenation process
11/06/2001USRE37438 Acetamidine derivatives and their use as inhibitors for the nitric oxide synthase
11/06/2001US6313142 Method for making 4-carboxyamino-2-substituted-1,2,3,4-tetrahydroquinoline
11/06/2001US6313139 Administering benzylamine derivative for therapy of psychiatric disorder in mammals
11/06/2001US6313109 Prenyl transferase inhibitors
11/06/2001US6313107 Methods of providing and using compounds having activity as inhibitors of cytochrome P450RAI
11/01/2001WO2001081355A1 Combretastatin a-1 phosphate and combretastatin b-1 phosphate prodrugs
11/01/2001WO2001081314A1 Naphthamidine urokinase inhibitors
11/01/2001WO2001081311A1 Substituted benzoic acid amides and use thereof for the inhibition of angiogenesis
11/01/2001WO2001081304A1 Inhibitors of dipeptidyl peptidase iv
11/01/2001US20010037039 Non-peptidic; inhibits trypsin-like protease, thrombin and embolus formation; anticoagulant
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