Patents
Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892)
06/1994
06/14/1994US5321131 Site-specific functionalization of oligodeoxynucleotides for non-radioactive labelling
06/14/1994US5320958 Isolated bacterial reverse transcriptase
06/14/1994US5320941 DNA sequence encoding mas onhcogene, polypeptides encoded therefrom and diagnostic and other methods based therefrom
06/09/1994WO1994012670A2 Process for typing of hcv isolates
06/09/1994WO1994012668A1 Mammalian muscle nad:arginine adp-ribosyltransferase
06/09/1994WO1994012665A1 Quantitative detection of macromolecules with fluorescent oligonucleotides
06/09/1994WO1994012650A2 Activating expression of an amplifying endogenous gene by homologous recombination
06/09/1994WO1994012649A2 Gene therapy for cystic fibrosis
06/09/1994WO1994012639A2 Interleukin-3 (il-3) mutant polypeptides
06/09/1994WO1994012638A2 Interleukin-3 (il-3) multiple mutation polypeptides
06/09/1994WO1994012539A1 Multifunctional neurotrophic factors
06/09/1994WO1994012535A1 Progenitor b cell stimulating factor
06/09/1994WO1994012533A1 Gp41 mutants and their use as hiv therapeutics
06/09/1994WO1994012528A1 Subtilin variant of enhanced stability and activity
06/09/1994WO1994012518A2 Reagent for coupling various substances to nucleic acids, and a method of preparing the reagent
06/09/1994WO1994012517A1 Sequence-specific binding polymers for duplex nucleic acids
06/09/1994WO1994012516A1 Permeability enhancers for ionic therapeutic polymers
06/09/1994WO1994012515A1 Methods for treatment of enzyme preparations
06/09/1994WO1994012513A1 Aids therapeutics based on hiv ma peptides
06/09/1994WO1994012216A1 Sequential targeting of tumor sites with oligonucleotide conjugates of antibody and complementary oligonucleotide conjugates of chelated radionuclide
06/09/1994WO1994006913A3 Recombinant proteins of a pakistani strain of hepatitis e and their use in diagnostic methods and vaccines
06/09/1994CA2592997A1 Pseudo-adenovirus vectors
06/09/1994CA2151032A1 Activating expression of an amplifying endogenous gene by homologous recombination
06/09/1994CA2150477A1 Sequential targeting of tumor sites with oligonucleotide conjugates of antibody and complementary oligonucleotide conjugates of chelated radionuclide
06/09/1994CA2150117A1 Interleukin-3 (il-3) mutant polypeptides
06/09/1994CA2150116A1 Interleukin-3 (il-3) multiple mutation polypeptides
06/09/1994CA2150028A1 Gp41 mutants and their use as hiv therapeutics
06/09/1994CA2150027A1 Aids therapeutics based on hiv ma peptides
06/09/1994CA2150025A1 Subtilin variant of enhanced stability and activity
06/09/1994CA2149862A1 Multifunctional neurotrophic factors
06/09/1994CA2149763A1 Progenitor b cell stimulating factor
06/08/1994EP0600627A1 Human Id genes
06/08/1994EP0533854A4 Pcr primers for detection of legionella species and methods for controlling visual intensity in hybridization assays
06/08/1994EP0407444B1 Apparatus and method for automated purification of extra-chromosomal dna from a cell suspension in a container
06/08/1994EP0225887B1 A method and a hybrid promoter for controlling exogenous gene transcription
06/08/1994CN1087681A Novel antibodies for conferring passive immunity against infection by a pathogen in humans
06/07/1994US5319080 Antiviral agents
06/07/1994US5319079 Process for terminal substituting of a polynucleotide
06/06/1994EP0643721A4 Method of synthesizing sulfurized oligonucleotide analogs.
06/01/1994EP0599338A2 Method for detecting target nucleic acid
06/01/1994DE4228458A1 Multicistronische Expressionseinheiten und deren Verwendung Multicistronic expression units and their use
05/1994
05/31/1994US5317098 Non-radioisotope tagging of fragments
05/31/1994US5316925 T-cell receptor specific for antigen polypeptides and related polynucleotides
05/31/1994US5316920 Lymphocyte activation antigen HB15, a member of the immunoglobulin superfamily
05/26/1994WO1994011534A1 Formation of triple helix complexes of single stranded nucleic acids using nucleoside oligomers which comprise pyrimidine analogs
05/26/1994WO1994011531A1 Identification of neoplasms by detection of genetic insertions and deletions
05/26/1994WO1994011530A1 Positional sequencing by hybridization
05/26/1994WO1994011522A2 Vector for the expression of therapy-relevant genes
05/26/1994WO1994011516A1 Genes for microsomal delta-12 fatty acid desaturases and related enzymes from plants
05/26/1994WO1994011513A1 Heat shock proteins and the treatment of tumours
05/26/1994WO1994011512A2 Allergenic proteins and peptides from japanese cedar pollen
05/26/1994WO1994011504A1 C-c ckr-1, c-c chemokine receptor
05/26/1994WO1994011501A1 cDNAs ENCODING HUMAN NMDA-22A RECEPTOR SUBUNIT AND ISOFORMS OF THE HUMAN NMDA-R1 RECEPTOR SUBUNIT, TRANSFECTED CELL LINE EXPRESSING THEM
05/26/1994WO1994011500A1 Novel polypeptides having opioid receptor activity, nucleic acids coding therefor and uses thereof
05/26/1994WO1994011499A1 Flk-1 is a receptor for vascular endothelial growth factor
05/26/1994WO1994011496A1 Soluble peptides having constrained, secondary conformation in solution and method of making same
05/26/1994WO1994011494A1 Antisense oligonucleotides to inhibit expression of mutated and wild type genes for collagen
05/26/1994WO1994011384A1 Novel cytokine designated elk ligand
05/26/1994WO1994011383A1 A representational approach to dna analysis
05/26/1994WO1994011305A1 Separation of nucleic acid fragments
05/26/1994WO1994011029A1 Human tissue factor related dna segments, polypeptides and antibodies
05/26/1994WO1994011023A1 Monoclonal antibody which specifically binds to tumor vascular endothelium and uses thereof
05/26/1994WO1994011011A1 Treatment of autoimmune diseases by inducing tolerance to cells, tissues and organs
05/26/1994WO1994009129A3 Method of cleaving specific strands of rna
05/26/1994WO1994008002A3 Methods and compositions for controlling translation of hcv proteins
05/26/1994DE4239531A1 Reagenz zur Kupplung verschiedener Substanzen an Nukleinsäuren sowie Verfahren zu dessen Herstellung Reagent for the coupling of different substances to nucleic acids, and methods for its preparation
05/26/1994CA2149626A1 Formation of triple helix complexes of single stranded nucleic acids using nucleoside oligomers which comprise pyrimidine analogs
05/26/1994CA2149318A1 Identification of neoplasms by detection of genetic insertions and deletions
05/26/1994CA2149309A1 Heat shock proteins and the treatment of tumours
05/26/1994CA2149249A1 A representational approach to dna analysis
05/26/1994CA2149056A1 Novel polypeptides with opioid receptor activity, nucleic acids encoding these substances and uses thereof
05/26/1994CA2148838A1 Soluble peptides having constrained, secondary conformation in solution and method of making same
05/26/1994CA2148835A1 Treatment of autoimmune diseases by inducing tolerance to cells, tissues and organs
05/26/1994CA2148713A1 Allergenic proteins and peptides from japanese cedar pollen
05/26/1994CA2148687A1 Antisense oligonucleotides to inhibit expression of mutated and wild type genes for collagen
05/26/1994CA2148484A1 Novel cytokine designated elk ligand
05/26/1994CA2138009A1 Production of monoclonal recombinant antibodies without the use of hybridomas by iin vitro spleen fragment culture combined with isothermal self-sustained sequence replication of rna
05/25/1994EP0598589A2 Method for the production of proteins in plant fluids
05/25/1994EP0252146B1 Nuclear factors associated with transcriptional regulation
05/19/1994DE4238778A1 Vektor zur Expression von therapeutisch relevanten Genen Vector for Expression of therapeutically relevant genes
05/18/1994EP0596918A1 Amplification of target nucleic acids using gap filling ligase chain reaction
05/18/1994EP0596901A1 CHIMERIC tRNA?LYS -RIBOZYME MOLECULES
05/18/1994EP0570518A4 Methods and apparatus for improved luminescence assays
05/18/1994EP0543889A4 Incorporation of selectably clevable and/or abasic sites into oligonucleotide chains and reagents therefor
05/18/1994EP0463043B1 Method for stabilizing the hybridization of complementary polynucleotide sequences
05/18/1994EP0266399B1 Replicative rna reporter systems
05/18/1994CN1086823A Process for extracting and separating high content "tikejining"
05/18/1994CN1024556C Process for nucleic acid derivatives
05/17/1994US5312921 Dyes designed for high sensitivity detection of double-stranded DNA
05/11/1994WO1994010343A1 Methods of detecting micrometastasis of prostate cancer
05/11/1994WO1994010341A1 Probe for diagnosing infectious diseases
05/11/1994WO1994010338A1 Nuclear hormone receptor-interacting polypeptides and related molecules and methods
05/11/1994WO1994010335A2 Assay methods
05/11/1994WO1994010318A1 Thrombin activatable plasminogen derivatives
05/11/1994WO1994010314A1 Allergenic proteins and peptides from johnson grass pollen
05/11/1994WO1994010309A1 Novel p-selectin ligand protein
05/11/1994WO1994010307A1 Transcription factor dp-1
05/11/1994WO1994010305A1 Transformed endothelial cells
05/11/1994WO1994010301A1 TNF-α RIBOZYMES AND DEGRADATION RESISTANT mRNA DERIVATIVES LINKED TO TNF-α RIBOZYMES
05/11/1994WO1994010203A2 Op-3-induced morphogenesis