Patents
Sitemap › C07 - Organic chemistry › C07D - Heterocyclic compounds › C07D 477 - Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula: , e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Patents for C07D 477 - Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula: , e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring (2,484)
12/1990
12/11/1990US4977256 Reacting with zinc powder in buffer
12/08/1990CA2018487A1 2- (substituted-dibenzofuranyl and dibenzothienyl) carbapenem antibacterial agents
11/1990
11/27/1990US4973687 Synthesis of carbapenems using N-substituted azetidinones
11/13/1990CA1276156C Enantioselective process for producing 1-beta- methylcarbapenem antibiotic intermediates
10/1990
10/31/1990EP0395219A2 Cephalosporins and their homologues, process for their preparation and pharmaceutical compositions
10/31/1990EP0394991A1 1-Azabicyclo(3.2.0)Hept-2-Ene-2-carboxylic acid compounds
10/28/1990CA2015360A1 1-azabicyclo¬3.2.0|hept-2-ene-2-carboxylic acid compounds
10/17/1990EP0392681A1 Antibacterial 2-carbapenem derivatives
10/17/1990CN1046164A Antibacterial 2-carbapenem derivatives
10/16/1990US4963544 3-pyrrolidinylthio-1-azabicyclo[3.2.0]-hept-2-ene-2-carboxylic acid compounds
10/16/1990US4963543 Bactericides, treating infectious diseases; thienamycins
10/09/1990US4962103 Carbapenem compounds and production thereof
10/09/1990US4962101 2-(Heterocyclylalkyl)phenyl carbapenem antibacterial agents
10/04/1990WO1990011284A1 Antibacterial 2-carbapenem derivatives
10/02/1990US4960879 Process for carbapenem intermediates
09/1990
09/30/1990CA2013391A1 Compounds
09/28/1990CA2013024A1 Antibacterial 2-carbapenem derivatives
09/25/1990CA1274514A1 6-¬1-hydroxyethyl|-2-sr.sup.8-1-methyl-1- carbadethiapen-2-em-3-carboxylic acids
09/04/1990CA1273630A1 Deprotection of allylic esters and ethers
08/1990
08/29/1990EP0384732A2 Deblocking process for allyl esters with regeneratable polymer supported pd (0)
08/28/1990US4952397 2-quaternary heteroarylalkylthio carbapenems having an acid moiety substituent
08/23/1990CA2010659A1 Deblocking process for allyl esters with regeneratable polymer supported pd (0)
08/21/1990CA1273015A1 Carbapenems with quaternized heterothioalkylthio substitution at position 2
08/21/1990CA1273014A1 Carbapenem process
08/21/1990CA1273013A1 1-methylcarbapenems having a 2-quaternary heteroarylalkylthio substituent
08/21/1990CA1273012A1 1-methylcarbapenems having an externally alkylated mono- of bicyclic 2-quarternary heteroarylalkylthio substituent
08/21/1990CA1273011A1 Carbapenems having an externally alkylated mono- or bicyclic 2-quaternary heteroarylalkylthio substituent
08/21/1990CA1273010A1 Carbapenem process
08/21/1990CA1273009A1 Carbapenem antibiotics
08/14/1990CA1272720A1 N-amino quaternized heteroarylium carbapenem antibacterial agents
08/14/1990CA1272719A1 Carbapenem antibiotics
08/08/1990EP0381534A1 Novel spirocyclic 6-amido-carbapenems
08/08/1990EP0381532A1 Novel 6-amido-1-methyl carbapenams
08/02/1990CA2009108A1 Spirocyclic 6-amidocarpabenems
08/02/1990CA2009107A1 6-amido-1-methyl carbapenams
07/1990
07/24/1990US4943569 B-lactam compounds
07/10/1990US4940788 Process for preparing azetidinones
07/04/1990EP0376355A1 2-Quaternary heteroarylalkythio carbapenems
06/1990
06/13/1990EP0372582A2 6-Aminoalkyl carbapenems
06/12/1990US4933333 β-lactam compounds
06/09/1990CA2004798A1 6-aminoalkyl carbapenems
06/05/1990CA1269978A1 Carbapenem antibiotics
05/1990
05/16/1990EP0368259A1 Carbapenem derivatives
05/15/1990US4925935 Methods for the manufacture of (1R,5S,6S)-2-[(6,7-dihydro-5H-pyrazolo[1,2-a][1,2,4]triazolium-6-yl]thio-6-[R-1-hydroxyethyl]-1-methyl-carbapenem-3-carboxylate
05/15/1990US4925838 3-pyrrolidinylthio-1-azabicyclo[3.2.0]-hept-2-ene-2-carboxylic acid compounds
05/15/1990US4925836 Antibacterially effective methods and compositions based upon (1R,5S,6S)-2-[(6,7-dihydro-5H-pyrazolo[1,2-a][1,2,4]triazolium-6-yl)]thio-6-[R-1-hydroxyethyl]-1-methyl-carbapenem-3-caroxylate and salts therefore
05/08/1990US4923857 3-Alkenyl-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid compounds
05/03/1990WO1990004594A1 Novel antimicrobial quinolonyl lactam esters
05/03/1990WO1990004591A1 Novel antimicrobial dithiocarbamoyl quinolones
05/02/1990EP0366643A2 Novel antimicrobial dithiocarbamoyl quinolones
05/02/1990EP0366641A2 Novel antimicrobial quinolonyl lactam esters
05/02/1990EP0366193A2 Novel antimicrobial quinolonyl lactams
05/02/1990EP0366189A2 Novel antimicrobial lactam-quinolones
05/01/1990US4921852 Carbapenicillins
04/1990
04/18/1990EP0364033A2 Stereoselective process for producing 1-beta-methylcarbapenem antibiotic intermediates
04/17/1990US4918188 Intermediates for penicillin and carbapenicillin antibiotics
04/17/1990US4918185 Process for carbon-carbon bond formation at the C-4 position of 3-acylaminoazetidinones and products and starting materials therefor
03/1990
03/14/1990EP0358085A1 (1R,5S,6S)-6-[(R)-1-Hydroxyethyl]-1-methyl-2-[(1-alkyl-1,2,4-triazolium-2-yl)alkyl]-thio-carbapenem-3-carboxylic acid derivatives
01/1990
01/16/1990US4894450 Forming an enol phosphate intermediate
01/11/1990WO1990000170A1 Novel 6-amido-1-methylcarbapenems
01/10/1990EP0350211A2 Novel 6-amido-1-methyl carbapenems
01/10/1990EP0350210A2 Novel 6-amido-1-methyl-2-(substituted-thio)-carbapenems
01/10/1990CN1038645A 3-pyrrolidinylthio-1-azabicyclo (3,2,0)-hept-2-ene-2-carboxylic acid derivatives and their preparation
01/09/1990US4892869 Antibiotics
12/1989
12/19/1989US4888344 Carbapenem compound in crystalline form, and its production and use
11/1989
11/29/1989EP0343499A1 3-Pyrrolidinylthio-1-azabicyclo(3,2,0) hept-2-ene-2-carboxylic acid compounds
11/21/1989CA1263117A1 Carbapenems, their production and use
11/15/1989EP0341557A1 3-pyrrolidinylthio-1-azabicyclo(3.2.0)-hept-2-ene-2-carboxylic acid derivatives and their preparation
11/15/1989CN1037149A 3-alkenyl-1-azabicyclo (3.2.0) hept-2-ene-2-carboxylic acid compounds
11/14/1989US4880922 Bactericides
11/14/1989US4880793 Bactericides, unsaturated carboxylic acid, amides
10/1989
10/24/1989US4876383 Amino acid derivatives, their production and use in preparing carbapenem and carbapenam compounds
10/18/1989EP0337637A1 2-(Heterocyclylthio)carbapenem derivatives their preparation and their use as antibiotics
10/11/1989EP0336143A1 A new process for carbapenem intermediates
10/03/1989US4871873 Oxidation of arylmethylketones with dimethyl sulfoxide in hydrobromic acid; reacting with aromatic amine
09/1989
09/26/1989CA1260945A1 Carbapenem antibiotics
09/20/1989EP0333265A2 Process for synthesis of arylglyoxal arylimines
09/20/1989EP0333175A1 3-Pyrrolidinylthio-1-azabicyclo (3.2.0)hept-2-ene-2-carboxylic acid compounds
09/12/1989US4866171 Thienamycin antibiotic
09/05/1989US4863916 Substituted 6-hydroxymethyl-carbapenem antibiotics
08/1989
08/30/1989EP0330108A1 3-Alkenyl-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid compounds
08/09/1989EP0326640A1 (1R,5S,6S)-2-substituted thio-6 (R)-1-hydroxyethyl -1-methyl-carbapenem - carboxylic acid derivatives
07/1989
07/18/1989US4849516 Penicillin and cephalosporin antibiotic intermediates
07/04/1989US4845261 Process for bis(substituted phenyl) phosphorohalidates
07/04/1989CA1256867A1 1,2-benzisoxazol-3-yl and 1,2-benzisothiazol-3-yl derivatives
06/1989
06/20/1989US4841042 Process for the preparation of carbapenem intermediates
06/20/1989US4840946 Benzazolythio-carbapenem antibiotics
06/13/1989US4839352 N-acyl derivatives of thienamycin
06/07/1989EP0318767A2 Esters of pharmacologically active carboxylic acids splittable under physiological conditions
05/1989
05/23/1989US4833167 Antibiotics, bactericides
05/23/1989CA1254562A1 Carbapenem compounds, their preparation and use
04/1989
04/18/1989US4822787 3-pyrrolidinylthio-1-azabicyclo(3.2.0)-hept-2-ene-2-carboxylic acid compounds and antimicrobial activity thereof
04/11/1989US4820817 Process for preparing 3-substituted-6-substituted-7-oxo-1-azabicycl(3.2.0)-hept-2-ene-2-carboxylic acid
04/11/1989US4820815 Useful as antibacterials or to form fused bicyclic b-lactam antibiotics like carbapenems
03/1989
03/14/1989US4812563 Antibiotics
03/08/1989EP0306266A1 Azetidinone n-phosphonomethyl esters
03/07/1989CA1250839A1 Fluoralkylated carbapenem derivatives
02/1989
02/14/1989US4804663 Psychological disorders
01/1989
01/24/1989CA1249279A1 Process for carbon-carbon bond formation at the c-4 position of 3-acylaminoazetidinones
12/1988
12/13/1988CA1246450A1 Combination of 2-substituted carbapenems with cipeptide inhibitors
1 ... 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25