Patents for C07D 477 - Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula: , e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring (2,484) |
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10/15/1980 | EP0017246A1 Antibiotic PA-31088-IV, its salts with bases, a process for its manufacture, pharmaceutical compositions containing this antibiotic, streptomyces tokunonensis PA-31088 and its mutants |
10/07/1980 | US4226870 O-, N- and carboxyl derivatives of thienamycin |
09/23/1980 | US4224336 3-(2-Aminoethylthio)-6-amido-7-oxo-1-azabicyclo[3.2.0]-hept-2-ene-2-carboxylic acid |
09/16/1980 | US4223038 Bicyclic β-lactam antibiotics |
08/19/1980 | US4218463 3-Substituted thio-6-amido-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid |
08/19/1980 | US4218462 6-(1-Hydroxyethyl)-2-(2-aminoethylthio)-1-substituted-1-carbade-thiapen-2-em-3-carboxylic acids |
08/19/1980 | US4218459 6-Amido-1-carba-2-penem-3-carboxylic acid |
08/12/1980 | US4217453 6-Amido-3-substituted-amino-1-azabicyclo[3.2.0]hept-2-en-7-one-2-carboxylic acid |
08/12/1980 | CA1083577A1 Substitutes n-methylene derivatives of thienamycin |
07/15/1980 | US4212807 Process for deacylating N-acyl-6-substituted-2-[2-aminoethylthio]-1-carbadethiapen-2-em-3-carboxylic acids |
07/08/1980 | US4211707 Process for hydrolytically cleaving O-sulfo thienamycins |
07/01/1980 | US4210662 Antibacterial, synergists for penicillins and cephalosporins |
07/01/1980 | US4210661 Thienamycins/and derivatives |
06/17/1980 | US4208422 1-Substituted-pen-2-em-3-carboxylic acids |
06/17/1980 | US4208330 O-Derivatives of thienamycin |
06/10/1980 | US4207323 6-Substituted methyl penicillins, derivatives and analogues thereof |
06/03/1980 | US4206219 Antibiotics |
06/03/1980 | US4206202 Antibiotic mm13902 from streptomyces olivaceus |
05/28/1980 | EP0011173A1 Process for producing antibiotic beta-lactam compounds |
05/27/1980 | US4205067 Synergistic activity of thienamycin deri derivatives |
05/20/1980 | US4203973 Antibiotics |
05/20/1980 | US4203902 Process for preparing 6- and 2-substituted-1-carbadethiapen-2-em-3-carboxylic acids |
05/14/1980 | EP0010573A1 Novel Z-2-acylamino-3-monosubstituted propenic acids and their esters and salts, and processes for preparing them |
04/30/1980 | EP0010317A1 6-, 1- and 2-substituted-1-carbapen-2-em-3-carboxylic acids, processes for the preparation of such compounds and pharmaceutical composition comprising such compounds |
04/30/1980 | EP0010316A1 1-, 6- and 2-substituted-1-carba-2-penem-3-carboxylic acids, process for preparing the same and pharmaceutical compositions containing the same |
04/30/1980 | EP0010312A2 Process for the preparation of 6-hydroxymethyl-2-(beta-aminoethylthio)-1-carbadethiapen-2-em-3-carboxylic acid and intermediates useful in this process |
04/15/1980 | US4198338 Process for purifying thienamycin |
04/01/1980 | US4196211 Antibiotic |
03/19/1980 | EP0008888A1 Beta-lactam antibacterial compounds, their preparation and pharmaceutical compositions containing them |
03/19/1980 | EP0008885A1 Beta-lactam compounds, their preparation and use |
03/18/1980 | US4194047 Substituted N-methylene derivatives of thienamycin |
03/05/1980 | EP0008514A1 Beta-lactam anti-bacterials, compositions containing them and a process for their preparation |
03/05/1980 | EP0008497A1 Beta-lactam-containing compounds, their preparation and pharmaceutical compositions containing them |
02/20/1980 | EP0007973A1 Process for the preparation of thienamycin and intermediates |
02/19/1980 | US4189493 N-heterocyclic derivatives of thienamycin |
02/19/1980 | US4189473 Antibiotic MM 13902 |
02/06/1980 | EP0007753A1 Beta-lactam antibacterial agents, a process for their preparation and pharmaceutical compositions containing them |
02/06/1980 | EP0007614A1 An antibacterial composition of thienamycin-type compound and a dipeptidase inhibitor |
01/23/1980 | EP0007152A1 Beta-lactam antibiotics, preparation and use |
01/09/1980 | EP0006639A1 Crystalline N-formimidoyl thienamycin |
01/01/1980 | US4181733 Carboxyl derivatives of thienamycin |
01/01/1980 | US4181716 Purification of anitbiotic mm 455oa by chromatography on cellulose |
12/18/1979 | US4179498 Streptomycetal antibiotic |
12/12/1979 | EP0005889A1 Process for the preparation of beta-lactam derivatives, the novel derivatives so obtainable and pharmaceutical compositions containing them |
11/14/1979 | EP0005349A1 Alkylcarbapenems, their preparation, use in pharmaceutical compositions and intermediates |
11/14/1979 | EP0005348A1 Carbapenem derivatives, a process for their preparation and pharmaceutical compositions containing them |
11/13/1979 | US4174316 Antibiotics |
10/23/1979 | US4172144 Schiff's base derivatives of thienamycin |
10/23/1979 | US4172129 Antibiotics |
09/19/1979 | EP0004132A1 Esters of beta-lactam antibiotics, a process for their preparation pharmaceutical compositions containing them and the compounds for use as antibacterial agents |
09/18/1979 | US4168268 Process for isolating thienamycin |
09/18/1979 | US4168202 Process for producing antibiotics |
09/05/1979 | EP0003740A2 Beta-lactam antibiotics, a process for their preparation and pharmaceutical compositions containing them |
07/31/1979 | US4163051 Synergistic |
07/24/1979 | US4162323 Antibiotic N-acetyl-dehydro-thienamycin |
07/24/1979 | US4162304 Bactericides, thienomycins |
07/24/1979 | US4162193 By penicillin amidohydrolases |
07/17/1979 | CA1058540A1 Antibiotic mm 17880 from streptomyces olivaceus |
07/10/1979 | CA1058104A1 Antibiotic thienamycin from streptomyces cattleya |
06/27/1979 | EP0002564A1 Derivatives of 7-oxo-1-azabicyclo(3.2.0)-hept-2-ene-2-carboxylic acid, their preparation, pharmaceutical compositions containing them and intermediates |
05/30/1979 | EP0002058A1 3-(2-Aminoethylthio-6-ethyl-7-oxo-1-azabicylo-(3.2.0)-hept-2-en-2-carboxylic acid, process for preparing it and compositions comprising it |
05/08/1979 | US4153714 3-Thio-5-methyl-7-oxo-1-azabicyclo[3,2,0]hept-2-ene-2-carboxylic acid esters, their production and use |
05/02/1979 | EP0001628A1 3-Substituted-6-substituted-7-oxo-1-azabicyclo (3.2.0)-hept-2-ene-2-carboxylic acid, its preparation and pharmaceutical compositions containing it |
05/02/1979 | EP0001627A1 3-Substituted-6-(1'hydroxethyl)-7-oxo-1-azabicyclo(3.2.0.)-hept-2-ene-2-carboxylic acid, its preparation and pharmaceutical compositions containing it |
05/02/1979 | EP0001567A1 Thienamycin related antibiotics PS-6 and PS-7, process for their production and compositions containing them |
04/17/1979 | US4150145 Antibiotic, bactericides |
04/04/1979 | EP0001265A1 O-, N- and carboxyl derivatives of thienamycin sulfoxide and sulfone, their preparation and pharmaceuticals containing said compounds |
04/04/1979 | EP0001264A1 Substituted N-methylene derivatives of thienamycin sulfoxide and sulfone and their preparation |
03/27/1979 | US4146633 Δ3 -Thienamycin |
03/27/1979 | US4146610 Antibiotics mm13902 |
03/13/1979 | CA1050460A1 Production of antibiotic mm 13902 by streptomyces |
03/07/1979 | EP0000932A1 Production of N-acyl-thienamycins |
03/07/1979 | EP0000931A1 Enzymatic cleavage of N-acyl-thienamycins |
02/27/1979 | US4141986 Antibiotics 890A2 and 890A5 |
02/27/1979 | CA1049532A1 Antibiotics |
02/21/1979 | EP0000828A1 Synthetic beta-lactam compounds, a process for their preparation and compositions containing them |
01/23/1979 | US4135978 Production of n-acyl-thienamycins |
10/31/1978 | US4123547 Antibiotics |
09/12/1978 | US4113856 Antibiotic mm 13902 |
05/16/1978 | US4089969 Antiinflammatory, analgesic, antipyretic, smooth muscle relaxant |
03/28/1978 | US4081548 Antibiotics |
02/01/1977 | US4006060 Cultivation of streptomyces cattleya |
12/28/1976 | US4000161 Process for purifying thienamycin |
04/13/1976 | US3950357 Antibiotics |