Patents
Patents for C07D 477 - Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula: , e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring (2,484)
02/2015
02/11/2015EP2834242A2 An improved process for the preparation of carbapenem antibiotic
02/11/2015CN104341421A 一种工业化制备替比培南酯的方法 A method for the preparation of industrialized 比培南 ester
02/11/2015CN102558182B 一种厄他培南钠晶型及其制备方法 He imipenem a crystal of sodium and its preparation method Ecuador
02/05/2015US20150038700 Doripenem intermediate compound, preparation process therefor and use thereof, and preparation process for doripenem
01/2015
01/29/2015US20150031664 Novel crystal form of pyrrolidylthiocarbapenem derivative
01/07/2015CN104262523A 含有羧基的聚合物、其制备方法和用途、负载型催化剂以及培南类抗生素中间体的制备方法 Methods for preparing a polymer containing a carboxyl group, their preparation and use, the supported catalyst and imipenem antibiotic intermediates
12/2014
12/17/2014CN102348710B 利用锌粉制备美罗培南的改进方法 The use of zinc improved method for the preparation of meropenem
11/2014
11/11/2014US8884005 Method for the preparation of carbapenam compounds
09/2014
09/23/2014US8841444 Process for the preparation of carbapenem compounds
09/18/2014WO2014144285A1 Meropenem derivatives and uses thereof
09/17/2014EP2776440A1 Process for the preparation of polymorphs of doripenem
09/02/2014US8822445 Crystalline form of carbapenem derivative or its hydrates and preparation methods and uses thereof
07/2014
07/02/2014CN103894210A 一种可套用的美罗培南合成用钯炭催化剂 Meropenem synthesis with palladium on carbon catalyst can be applied in a
06/2014
06/26/2014WO2014097221A1 Process for the purification of biapenem
06/26/2014WO2014094659A1 Process for preparation of meropenem trihydrate crystals
06/18/2014CN102690266B Method for preparing ertapenem sodium
06/11/2014CN103848832A Purification method of ertapenem sodium
06/05/2014WO2014082226A1 Purification method of ertapenem sodium
06/04/2014CN102702203B Meropenem refining method
05/2014
05/29/2014US20140148595 Method for the preparation of carbapenam compounds
05/28/2014CN102633801B 替比培南酯的制备方法 Esters for the preparation of 比培南
05/20/2014US8729260 Process for the preparation of carbapenem using cabapenem intermediates and recovery of cabapenem
05/07/2014CN103772389A 一种厄他培南中间体的制备方法 A method for the preparation of his imipenem Eritrea intermediates
05/07/2014CN103059028B 一种替比培南匹伏酯的制备方法 A method for the preparation of esters 比培南 horsepower V
05/01/2014US20140121192 Methods of generating beta-lactamase resistant carbapenem compounds
04/2014
04/17/2014WO2014057079A1 Preparation of ertapenem intermediates
04/16/2014CN102372714B Method for preparing doripenem
04/09/2014CN103709166A Synthetic method for Tebipenem Pivoxil polymer impurity
04/09/2014CN103709165A Preparation technology of carbapenem antibiotics
04/09/2014CN101711250B Benzenesulfonamido methylene substituted mercapto pyrrolidine carbapenem derivatives
04/01/2014CA2515741C Crystal of synthetic intermediate of carbapenem
03/2014
03/26/2014CN103664949A Tebipenem pivoxil crystal and preparation method thereof
03/26/2014CN103664948A Crystal of intermediate of tebipenem pivoxil and preparation method thereof
03/26/2014CN103664947A Novel crystal form of carbapenem antimicrobial medicament and preparation method of novel crystal form
03/26/2014CN103664946A Industrial synthesis method of doripenem
03/26/2014CN102702202B By-product in synthesis process of tebipenem pivoxil and preparation method of by-product
03/12/2014CN103626771A Process for preparing doripenem
03/12/2014CN102633800B Crystals of meropenem intermediate, and preparation method and application thereof
02/2014
02/12/2014CN103570720A Meropenem raw medicine, preparation method thereof and pharmaceutical composition containing same
02/12/2014CN103570719A Meropenem raw medicine, preparation method thereof and pharmaceutical composition containing same
02/12/2014CN103570718A Meropenem raw medicine, preparation method thereof and pharmaceutical composition containing same
02/06/2014WO2014019282A1 Meropenem bulk drug, preparation method thereof and pharmaceutical composition containing same
01/2014
01/29/2014CN103537192A Membrane integration device for purifying and concentrating Ertapenem aqueous solution
01/22/2014CN103524508A Imipenem-hydrate crystallization method
01/22/2014CN103524507A Preparation method of ertapenem sodium salt
01/15/2014CN103506115A Preparation method of bimetallic catalyst used for carbapenem drug synthesis
12/2013
12/25/2013EP2675805A1 Method for the preparation of carbapenam compounds
12/25/2013CN102702201B Doripenem intermediate compound, preparation method and application of doripenem intermediate compound and preparation method for doripenem
12/18/2013CN103450203A Preparation method of meropenem
12/12/2013US20130331310 Prodrug of an Ice Inhibitor
12/05/2013WO2013150550A3 An improved process for the preparation of carbapenem antibiotic
11/2013
11/27/2013CN102452969B Doripenem side-chain compound and preparation method and application thereof
11/20/2013EP2303225B1 Compositions of Carbon Dioxide Adduct of Ertapenem and Polymorphic Forms of Ertapenem Monosodium Salt
11/20/2013CN102432611B Dual-protection ertapenem crystal and preparation method thereof
11/06/2013EP2660242A1 Crystalline form of ertapenem sodium and preparation method therefor
11/05/2013CA2740508C Improved process for the preparation of carbapenem using carbapenem intermediates and recovery of carbapenem
11/05/2013CA2596951C Process for production of carbapenem derivative and crystalline intermediate therefor
10/2013
10/24/2013WO2013157583A1 Novel carbapenem compound
10/24/2013US20130281427 Crystalline form of ertapenem sodium and preparation method therefor
10/10/2013WO2013150550A2 An improved process for the preparation of carbapenem antibiotic
10/03/2013WO2013143266A1 Doripenem intermediate compound, preparation process therefor and use thereof, and preparation process for doripenem
09/2013
09/26/2013US20130253184 Process for the preparation of pure meropenem trihydrate
09/18/2013CN102363617B Ertapenem monosodium salt crystal and preparation method thereof
09/04/2013CN103275082A Preparation method of meropenem
09/04/2013CN103275081A Carbapenems antibiotics
08/2013
08/28/2013EP2630147A1 A process for the preparation of pure meropenem trihydrate
08/22/2013WO2013121279A2 Process to prepare ertapenem
08/07/2013CN101880282B Purification method of pyrrolidine carbapenem antibiotics
07/2013
07/17/2013CN101628914B Meropenem intermediate in novel crystalline form and a method of manufacture of meropenem
07/10/2013CN203048834U Device for low-temperature separation and recovery of meropenem mother liquid by use of nanofiltration membrane
07/10/2013CN101432289B Improved method for the crystallization of intermediates of carbapenem antibiotics
07/04/2013US20130172313 Carbapenem Antibacterials with Gram-Negative Activity
06/2013
06/26/2013CN101973915B Intermediate of synthetic imipenem medicine as well as preparation method and application thereof
06/19/2013CN103159770A Crystal form of ertapenem monosodium salt
06/05/2013CN103130805A Doripenem intermediate solvate
05/2013
05/22/2013CN103113374A Carbapenem antibiotic and new synthetic process thereof
05/22/2013CN103113373A 1 beta-methyl carbapenem compound and synthetic process thereof
05/21/2013US8445673 Process for the preparation of sterile doripenem
05/16/2013WO2013068910A1 Process for the preparation of polymorphs of doripenem
05/16/2013WO2013067878A1 Ertapenem sodium crystal and preparation method thereof
05/15/2013EP2590978A2 Carbapenem antibacterials with gram-negative activity
05/15/2013EP2590977A1 Fluorescent carbapenems
05/15/2013CN102351860B Synthesis method of panipenem and intermediates thereof
04/2013
04/25/2013US20130102017 Fluorescent carbapenems
04/24/2013CN103059028A Preparation method of tebipenem pivoxil
04/24/2013CN103059027A Method for preparing tebipenem pivoxil
04/24/2013CN103059026A Preparation method of tebipenem ester
04/24/2013CN103059025A Preparation method of carbapenem bicyclic parent nucleus
04/17/2013CN103044429A Preparation method of meropenem
04/17/2013CN103044428A Synthetic method of antibiotic
04/17/2013CN103041805A Preparation method of high-activity palladium-carbon catalyst for synthesis of imipenem antibiotics
04/11/2013US20130090325 Crystalline form of carbapenem derivative or its hydrates and preparation methods and uses thereof
04/03/2013CN103012406A Preparation method of antibacterial agent
03/2013
03/28/2013US20130079322 Crystalline of carbapenem derivative or its hydrate, preparation methods and uses thereof
03/27/2013CN102153555B Carbapenem compound containing amido formacyl heterocycle
03/27/2013CN101613352B Carbapenem derivatives containing formamide heterocyclic mercaptopyrrolidine
03/20/2013CN102977102A Preparation method of meropenem trihydrate crystal
03/20/2013CN102977101A Doripenem monohydrate, pharmaceutical compositions thereof, preparation method thereof and uses thereof
03/14/2013WO2013034087A1 Doripenem hydrate crystal and preparation method therefor
03/14/2013US20130066066 Method for Late Introduction of the (8R)-Hydroxyl Group Carbapenem Beta-Lactam Antibiotic Synthesis
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