Patents
Patents for C07D 477 - Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula: , e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring (2,484)
11/1988
11/29/1988US4788282 Carbapenicillins
11/23/1988EP0292191A1 2-(Substituted methyl)-1-alkylcarbapenem derivatives
11/09/1988EP0289801A1 (1R,5S,6S)-2-(substituted thio)-6-[(R)-1-hydroxy-ethyl]-1-methyl-carbapenem-3-carboxylic-acid derivatives
11/08/1988US4783453 2-aza-substituted 1-carbadethiapen-2-em-3-carboxylic acids
11/08/1988CA1244439A1 Compounds having a 7-oxo-1-azabicyclo¬3.2.0| hept-2-ene-2-carboxylic acid skeleton and process for production thereof
11/01/1988US4782051 2-aza-substituted 1-carbadethiapen-2-em-3 carboxylic acids
10/1988
10/04/1988US4775669 Antibiotic
09/1988
09/13/1988US4771135 Antibiotic intermediates
09/13/1988US4771046 Antibiotics
09/07/1988EP0280771A1 3-Pyrrolidinylthio-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid derivatives and processes for the preparation thereof
09/06/1988US4769451 Synthesis of carbapenems using n-substituted azetidinones
09/06/1988CA1241656A1 Fluoralkylatedcarbapenem derivatives
08/1988
08/10/1988EP0277743A1 2-(heteroaryliumalkyl)phenyl carbapenem antibacterial agents
08/10/1988CN87107938A 3-pyrrolidinylthio-1-azabicyclo(3.2.0) hept-2-ene-2-carboxylic acid compounds and processes for preparation thereof
08/03/1988EP0276993A1 Process for preparing azetidinones
06/1988
06/29/1988EP0272456A1 3-Pyrrolidinylthio-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid compounds and processes for the preparation thereof
06/29/1988EP0272455A1 3-Pyrrolidinylthio-1-azabicyclo [3.2.0] hept-2-ene-2-carboxylic acid compounds
06/16/1988DE3641869A1 5-Substituted 2-amino-3-pyrazinethiols
06/09/1988DE3641872A1 Pyrazinylthiocarbapenems, processes for their preparation, and their use
06/01/1988EP0268963A1 Benzazolylthio-carbapenem antibiotics
05/1988
05/31/1988US4748238 Crystalline 1R,5S,6S,8R-1-methyl-2-(N,N-dimethylcarbamimidoylmethylthio)-6-(1-hydroxyethyl)-1-carbapen-2-em-3-carboxylic acid
05/24/1988US4746736 Carbapenem antibiotics
05/17/1988US4745201 Process for intermediates to 1-carbapenems and 1-carbacephems
05/17/1988US4745188 Process for preparing 3-substituted-6-substituted-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
04/1988
04/27/1988EP0265169A1 Oxadiazines & related compounds
04/27/1988EP0265117A1 2-substituted alkyl carbapenem antibacterials
04/26/1988US4740507 Carbapenem compounds and use
04/19/1988US4739048 Process for the preparation of thienamycin and intermediates
03/1988
03/22/1988US4732977 Bactericides
03/16/1988EP0259987A2 Amino acid derivatives and their production and use in preparing carbapenem and carbapenam compounds
03/08/1988US4729993 Enzyme inhibitor, antibiotics
02/1988
02/24/1988EP0256377A1 Carbapenem compound in crystalline form, and its production and use
02/16/1988US4725594 Carbapenems having an internally or externally alkylated mono- or bicyclic 2-quaternary heteroarylalxyl heteromethyl substituent
02/16/1988CA1232903A1 Azetidinone derivatives, a process for their preparation and their use as intermediates in the preparation of carbapenem antibiotics
01/1988
01/19/1988US4720491 Fluoralkylatedcarbapenem derivatives
01/19/1988US4720490 Fluoralkylatedcarbapenem derivatives
01/05/1988US4717728 Cyclic amidinyl and cyclic guanidinyl thio carbapenems
12/1987
12/15/1987US4713451 Antibiotic
12/02/1987EP0247431A1 Substituted 6-hydroxymethylcarbapenem antibiotics, process for their preparation and their use
12/01/1987US4710568 Bactericides
11/1987
11/17/1987US4707547 Process for preparing carbapenem compounds
11/04/1987EP0243686A2 Beta-lactam compounds, and their production
10/1987
10/21/1987EP0242134A2 N-amino quaternized heteroarylium carbapenem antibacterial agents
10/06/1987US4698339 Carbapenems, their production and use
09/1987
09/29/1987US4696923 Thienamycin antibiotics, bactericides
09/16/1987EP0237027A2 6-(Disubstituted amino) carbapenam compounds
09/09/1987EP0235823A2 Carbapenem antibiotics, a process for preparing them and pharmaceutical compositions containing them
08/1987
08/12/1987CN86107742A Heterocyclic compounds containing 4-thia-1-azabicyclo (3.2.0) heptane ring systems
08/05/1987EP0230771A2 Pyran derivatives
07/1987
07/28/1987USRE32465 AZA penem compounds
07/28/1987US4683301 Bactericides
07/22/1987EP0229384A2 Beta-lactam compounds and their production
07/14/1987US4680292 Carbapenems and 1-methylcarbapenems having a 2-heteroaryliumaliphatic substituent
05/1987
05/27/1987EP0223588A1 Process for the preparation of beta-lactam compounds
05/20/1987CN86105933A Carbapenem artibiotic
05/12/1987US4665170 Thienamycins, bactericides
05/12/1987US4665169 Carbapenem antibiotics
04/1987
04/21/1987US4659814 Salts of amino-beta-lactamic acids and process for the preparation thereof
04/15/1987EP0218415A1 Process for intermediates to 1-carbapenems and 1-carbacephems
04/07/1987CA1220215A1 Carbapenem intermediates
03/1987
03/03/1987US4647408 Carbapenem-type antibiotics
03/03/1987CA1218646A1 Deesterification to acids
02/1987
02/17/1987US4644061 Carbapenem antibiotics
02/11/1987CN86103410A Method and apparatus for preparing food foodstuffs
02/10/1987US4642341 Bactericides
02/04/1987CN86103521A Deprotection of allylic esters and ethers
02/03/1987US4640915 1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid derivatives
02/03/1987US4640799 Thienamycins
01/1987
01/21/1987EP0208889A1 2-Aza-substituted 1-carbadethiapen-2-EM-3-carboxylic acids
11/1986
11/25/1986CA1214462A1 Carbapenem derivatives, their preparation and compositions containing them
11/20/1986EP0202048A1 Carbapenem derivatives, their preparation, and pharmaceutical compositions containing them
10/1986
10/28/1986US4619787 Beta lactams
10/15/1986EP0197432A2 Enantioselective process for producing 1-beta-methylcarbapenem antibiotic intermediates
10/07/1986US4616038 Bactericides
10/01/1986EP0196132A2 1,2-Benzisoxazol-3-yl and 1,2-benzisothiazol-3-yl derivatives
10/01/1986EP0195963A1 Process for the preparation of carbapenem intermediates
10/01/1986CN86101906A Process for the preparation of novel 1,2-benzisoxazol-3-yl and 1,2-benzisothiazol-3-yl derivatives
09/1986
09/23/1986US4613595 Pencillin antibiotics
09/16/1986US4612325 5-Aroyl-6-alkylthio-1,2-dihydro-3H-pyrrolo(1,2-A)pyrrole-1-carboxylic acids and use thereof as analgesics and anti-inflammatories
09/09/1986US4610820 Process for the preparation of thienamycin and intermediates
08/1986
08/13/1986CN85109699A Preparation and use of carbapemem compounds
07/1986
07/30/1986EP0188816A1 Novel beta-lactams and their production
07/02/1986EP0186525A1 Carbapenem compounds, their preparation and use
07/02/1986EP0186057A1 Carbapenems having a 2-position substituent joined through an alkyleneheteroatom bridge
06/1986
06/25/1986EP0185315A1 Carbapenems and 1-methylcarbapenems having a 2-heteroaryliumaliphatic substituent
06/18/1986EP0184844A1 1-Methylcarbapenems having a 2-position substituent joined through an alkylenethio bridge
06/18/1986EP0184843A1 Carbapenems and 1-methylcarbapenems having an externally alkylated mono- or bicyclic 2-quaternary heteroarylalkyl substituent
06/18/1986EP0184842A2 Carbapenems having an internally or externally alkylated mono- or bicyclic 2-quaternary heteroarylalkyl heteromethyl substituent
05/1986
05/28/1986EP0182213A1 Carbapenem compounds and production thereof
04/1986
04/15/1986US4582643 6-(1-hydroxyethyl)-2-(2-aminoethylthio)-1,1-disubstituted-1-carbadethiapen-2-em-3-carboxylic acids
03/1986
03/18/1986US4576939 Penem derivatives
03/18/1986US4576746 Chemical intermediates for antibiotics
02/1986
02/05/1986EP0170073A1 1-Methylcarbapenems having an externally alkylated mono- or bicyclic 2-quaternary heteroarylalkylthio substituent
02/05/1986EP0170019A1 Carbapenems having an ether group at position 4
02/04/1986CA1200244A1 5-aroyl-6,-alkylthio-1,2-dihydro-3h-pyrrolo[1,2- 1] pyrrole-1-carboxylic acids and derivatives thereof
01/1986
01/29/1986EP0169410A1 Carbapenems having a 2-quaternary pyridine altylthio or pyridine alkenylthio substituent, compositions containing the same and combinations with DHP inhibitors
01/28/1986CA1199885A1 Isolation of chemically unstable antibiotics from fermentation solutions
01/22/1986EP0168707A1 1-Methylcarbapenems having a 2-quaternary heteroarylalkylthio substituent
01/21/1986CA1199644A1 Process for the preparation of heterocyclic acetic acid derivatives
01/08/1986EP0167139A1 Carbapenems having an externally alkylated 2-quaternary pyridiniumalkylthio substituent
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