Patents
Patents for C07D 477 - Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula: , e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring (2,484)
12/1985
12/27/1985EP0165384A1 Carbapenem derivatives, their preparation and compositions containing them
12/24/1985CA1198440A1 Carbapenem antibiotics
12/24/1985CA1198427A1 1-, and 1,1- disubstituted -6- substituted -2- carbamimidoyl -1- carbadethiapen-2-em -3- carboxylic acids
12/04/1985EP0163452A1 A novel process for carbon-carbon bond formation at the C-4 position of 3-acylaminoazetidinones
12/03/1985US4556517 Bactericide, beta-lactamase inhibition
11/1985
11/27/1985EP0162242A1 Crystalline dimethyliminothienamycin
11/27/1985EP0162193A1 Novel 2-penem-type compounds and pharmaceutical compositions contaning them
11/21/1985EP0161546A1 Combination of 2-substituted carbapenems with dipeptidase inhibitors
11/21/1985EP0161541A1 6-[1-Hydroxyethyl]-2-SR8-1-methyl-1-carba-dethiapen-2-em-3-carboxylic acids
11/13/1985EP0160876A1 1-Hetero-6-/1-Hydroxyethyl/-2-SR8-1-carbadethiapen-2-EM-3-carboxylic acids
11/12/1985US4552873 Bactericides
11/12/1985US4552696 Carbapenem antibiotics
11/06/1985EP0160391A1 Carbapenem derivatives and compositions containing them
10/1985
10/01/1985US4544557 6-(1-Hydroxyethyl)-2-(2-aminoethylthio)-3-tetrazoly-1-carbadethiapen-2-em
10/01/1985US4544502 Chiral synthesis of thienamycin from D-glucose
09/1985
09/24/1985US4543257 Penicillin antibiotics
09/03/1985US4539208 Combination of thienamycin-type antibiotics with dipeptidase inhibitors
09/03/1985US4539152 4-Substituted-2-oxoazetidine compounds
08/1985
08/20/1985US4536335 Carbapenem antibiotics
08/20/1985CA1192202A1 Thienamycin analogues
08/13/1985CA1191854A1 Thienamycin derivatives
07/1985
07/23/1985US4530841 6- And 6,6-disubstituted-3-substituted amino-1-azabicyclo-[3.2.0]hept-2-en-7-one-2-carboxylic acid
07/23/1985US4530791 β-Lactam antibiotics
07/23/1985CA1190931A1 Thienamycin intermediates
07/16/1985US4529597 Substituted penicillin antibiotic
07/16/1985US4529545 Isolation of chemically unstable antibiotics from fermentation solutions
07/09/1985CA1190236A1 Antibiotic synthesis
07/03/1985EP0146735A1 Optically uniform beta-lactams
07/02/1985CA1189866A1 Heterocyclic acetic acid derivatives and a process for the preparation thereof
06/1985
06/25/1985US4525582 Silyl, benzyl, p-nitrobenyl, or methyl esters of diazoacetate, a synthon used in the conversion of penicillin to thienamycin
06/25/1985US4525339 Beta-lactam antibiotic distributed in mono, di, and tri-glycerides of fatty acids
06/19/1985EP0144825A1 Cyclic guanidinyl thio carbapenems
06/04/1985US4521340 Pharmaceutically acceptable salts of the antibiotic C-19393 E5
05/1985
05/21/1985US4518529 Bactericides, disinfectants
05/14/1985US4517127 β-Lactam derivatives and process for production thereof
05/14/1985CA1187015A1 Antibiotic pa-39504-x.sub.3 and production thereof
04/1985
04/17/1985EP0137403A2 Carbapenems, their production and use
04/11/1985WO1985001502A1 7-oxo-1-azabicyclo ad3.2.0 bd hept-2-ene-2-carboxylic acid derivatives, process for their preparation, and their use
04/09/1985CA1185244A1 .beta.-LACTAM ACETIC ACID DERIVATIVES, THE PROCESS FOR PREPARING THEM, AND THEIR USE AS INTERMEDIATES FOR 1- AZABICYCLO¬3.2.0|HEPT-2-ENE ANTIBIOTICS
04/02/1985US4508648 Phosphoric ester of antibiotic OA-6129
03/1985
03/20/1985EP0134301A1 6-(1'-Hydroxyethyl)-3-substituted amino-1-azabicyclo(3.2.0)-hept-2-en-7-one-2-carboxylic acid
02/1985
02/13/1985EP0132987A1 Improvements in or relating to deesterification to acids
02/12/1985US4499278 Thienamycins
02/12/1985CA1182413A1 .beta.-LACTAM COMPOUNDS, PROCESS FOR PRODUCTION THEREOF, AND USE THEREOF AS MEDICINES
02/05/1985US4497742 Isomerization of β-lactam compounds
01/1985
01/22/1985US4495197 N-Carboxyl-thienamycin esters and analogs thereof as anti-inflammatory agents
01/15/1985US4493839 1-Carbapenem-3-carboxylic esters as anti-inflammatory agents
12/1984
12/25/1984US4490541 5(3)-Aminopyrazolo-3,4(4,5)-dicarboximide azo dyestuff intermediates
12/18/1984CA1179675A1 7-oxo-1-azabicyclo ¬3,2,0| heptene-2-derivatives
12/12/1984EP0127847A1 7-Oxo-4-thia-1-azabicyclo(3.2.0)hept-2-ene derivatives
12/05/1984EP0127541A2 Salts of amino-beta-lactamic acids and process for the preparation thereof
12/05/1984EP0126780A1 Carbapenem compound
11/1984
11/28/1984EP0126587A1 Carboxylic thio-pyrrolidinyl beta-lactam compounds and production thereof
11/13/1984CA1177832A1 ISOMERISATION OF .beta.-LACTAM COMPOUNDS AND NOVEL PRODUCTS OBTAINED THEREBY
10/1984
10/16/1984US4477662 2-Substituted thio carbapenem derivatives
10/09/1984CA1175841A1 .beta.-LACTAM ANTIBIOTICS, THEIR PREPARATION AND USE
09/1984
09/25/1984US4473578 β-Lactam antibiotics and their use
09/25/1984US4473502 Synthesis of thienamycin via (3SR, 4RS)-3-[1 (SR)-hydroxyethyl]-2-oxo-4-azetidineacetic acid
08/1984
08/28/1984US4468350 KA-6643-Series antibiotics, process for producing same and medical composition containing same
08/21/1984US4467107 Intermediates for thienamycin
08/21/1984US4466914 Process for the conversion of primary and secondary alcohols to their corresponding thiols and thiol esters
08/15/1984EP0116016A1 Carbapenem-type antibiotics and production thereof
08/14/1984US4465632 Process for preparing 1-6-and 2-substituted-1-carba-2-penem-3-carboxylic acids
08/07/1984US4464299 Antibacterial carbapenem compounds
07/1984
07/24/1984CA1171415A1 Carbapenams and carbapen-2-ems and process therefor
07/17/1984US4460507 Process for the preparation of thienamycin
07/11/1984EP0113101A1 6-(1-Hydroxyethyl)-2-SR8-1-methyl-1-carbadethiapen-2-em-3-carboxylic acid esters
06/1984
06/26/1984US4456686 Thienamycin from a streptomyces culture
06/20/1984EP0111286A1 Novel beta-lactam derivatives and process for production thereof
06/12/1984US4454332 Intermediate for synthesis of thienamycin
05/1984
05/29/1984US4451401 Antibiotics and process for production thereof
05/29/1984CA1168244A1 Process for 5-aroylation of 1,2-dihydro-3h- pyrrolo[1,2-a]pyrrole-1-carboxylic esters
05/16/1984EP0108295A1 Oral dosage form
05/15/1984US4448976 Using 3-azido-4-(cyano or carbomethoxy)-2,3,4,6-tetradeoxy-d-arabino-hexose trimethylene dithioacetal
05/15/1984US4448723 Bactericide, veternary drug
05/15/1984CA1167400A1 Ka-6643-series antibiotics, process for producing same and medical composition containing same
05/01/1984US4446146 β-Lactam containing compounds, their preparation and use
05/01/1984CA1166640A1 2-oxoazetidine derivatives and production thereof
04/1984
04/24/1984US4444783 β-Lactam antibacterial agents, a process for the preparation and use in pharmaceutical compositions
04/24/1984US4444685 Stereospecific synthesis of thienamycin from penicillin
04/18/1984EP0105658A1 Beta-lactam compounds
04/11/1984EP0105227A1 Process for producing beta-lactam compounds, and intermediates useful for their production
03/1984
03/27/1984CA1164460A1 Beta-lactam compounds and process for production thereof
03/20/1984US4438036 β-Lactam antibiotics their preparation and their use
03/07/1984EP0102239A1 Azetidinone derivatives, a process for their preparation and their use as intermediates in the preparation of carbapenem antibiotics
03/06/1984CA1163270A1 Carbapenem compounds and their production
03/06/1984CA1163220A1 Antibiotic sf-2103a substance and process for production thereof
02/1984
02/16/1984WO1984000547A1 Fluoralkylatedcarbapenem derivatives
02/14/1984US4431658 Aza penem compounds
02/14/1984US4431587 Beta-lactam antibacterial agents
01/1984
01/31/1984US4429128 Carbapenams and carbapen-2-ems and process therefor
01/31/1984US4428961 Thienamycin antibiotics
01/31/1984US4428960 Amino acid derivative antibiotics
01/24/1984US4427586 2-Oxoazetidine derivatives and production thereof
01/24/1984CA1161058A1 Z-2-acylamino-3-monosubstituted propenoates
01/17/1984US4426390 Novel β-lactam compounds, process for producing thereof, and use thereof as medicines
01/03/1984US4424230 6-(1'-Hydroxyethyl)-3-substituted amino-1-azabicyclo- 3.2.0!hept-2-en-7-one-2-carboxylic acid
01/03/1984CA1159782A1 Antibiotic pa-39504-x.sub.n and production thereof
12/1983
12/21/1983EP0096583A2 5-Aroyl-1,2-dihydro-3H-pyrrolo 1,2-a pyrrole-1-carboxylic acids and derivatives thereof, processes for their preparation, and intermediates therefor
12/20/1983US4421760 β-Lactam antibiotic, its preparation and use
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