Patents
Sitemap › C07 - Organic chemistry › C07D - Heterocyclic compounds › C07D 477 - Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula: , e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Patents for C07D 477 - Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula: , e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring (2,484)
11/1983
11/16/1983EP0093915A1 Novel beta-lactam derivatives
11/15/1983US4415497 Hydrolysis of the sulfate group of a carapenicillin derivative to a hydroxy; amino acid derivative antibiotics
11/08/1983US4414155 Synthesis of thienamycin via esters of (3SR, 4RS)-3-[(SR)-1-hydroxyethyl]-β,2-dioxo-4-azetidinebutanoic acid
11/01/1983US4413000 β-Lactam antibiotics, their preparation and use
10/1983
10/18/1983US4410533 β-Lactam antibiotics, their preparation and use
10/11/1983US4409147 Antibiotic, bactericides
10/05/1983EP0090366A1 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid derivatives, processes for the preparation thereof and pharmaceutical compositions containing them
10/04/1983US4407815 β-Lactam antibacterial compounds, their preparation and pharmaceutical compositions containing them
09/1983
09/27/1983US4406902 Dipeptidase inhibitors
09/21/1983EP0089139A2 Antibiotics, their preparation and use
09/20/1983US4405637 β-Lactam antibacterial agents
09/20/1983CA1153968A1 Antibiotic pa-31088-iv and production thereof
09/13/1983US4404218 Antibiotic SF-2103A substance and process for production thereof
08/1983
08/30/1983US4401595 4-Allyl azetidinone intermediate for β-lactam antibacterial agents
08/24/1983EP0086590A1 Antibacterial agents, their preparation and use
08/24/1983EP0086389A2 Aminopyrazole compounds
08/23/1983US4400323 3-[1-Hydroxyethyl]-4-carboxymethyl-azetidin-2-one
08/10/1983EP0085407A1 Derivatives of antibiotics 0A-6129A, 0A-6129B1 and 0A-6129B2 and their preparation method
08/09/1983US4397861 Antibiotics
08/09/1983US4397784 Amino acid derivative antibiotics
08/04/1983WO1983002614A1 5,6-cis-carbapenem-3-carboxylic acid derivatives and process for their preparation
06/1983
06/22/1983EP0082133A2 A process for preparing intermediates useful for preparing 2-substituted-6-substituted-1-carbadethiapen-2-em-3-carboxylic acids
06/15/1983EP0081312A2 Antibiotics, their preparation and use
06/07/1983US4387052 Antibiotic PA-39504-X3 and production thereof
06/07/1983US4387051 β-Lactam antibiotics, their preparation and their use in pharmaceutical compositions
06/01/1983EP0080166A1 Isolation of chemically unstable antibiotics from fermentation solutions
05/1983
05/31/1983US4386029 Ester cleavage of a 6-(1-hydroxyethyl)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid
05/24/1983US4384998 Decyclization, reaction with mercaptans, alcoholysis, catalytic hydrogenation, then cyclization
05/18/1983EP0079244A2 Pluracidomycin B,C, and D and analogs thereof, their production and a microorganism for use therein
05/18/1983EP0079167A1 A carbapenem compound, preparation and use
05/17/1983US4383946 Process for the preparation of 1-carbapenems and intermediates via silyl-substituted dithioacetals
05/17/1983US4383945 Thienamycin intermediates
05/10/1983US4382949 2-(Amino acid-thio)-1-carbapen-2-em-3-carboxylic acids and congeners
05/04/1983EP0078026A2 Antibiotic synthesis
04/1983
04/13/1983EP0076466A2 Novel phosphoric ester of antibiotic OA-6129 and its preparation method
03/1983
03/23/1983EP0074599A1 5,6-cis-Carbapenem derivatives, their production and use
03/22/1983US4377591 7-Oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid derivatives, their use and preparation
03/17/1983WO1983000867A1 5,6-cis-carbapenem-3-carboxylic acid derivatives and process for their preparation
03/15/1983US4376774 Containing a pyridinium ring
03/15/1983CA1142867A1 ANTIBIOTIC .beta.-LACTAM COMPOUNDS, PRODUCTION THEREOF, AND ITS USE AS ANTIMICROBIAL AGENT
03/09/1983EP0073451A2 Carbapenam compound and processes for the preparation thereof
03/02/1983EP0073100A1 Beta-lactam compounds, their preparation and their use
03/01/1983US4375433 Process for the preparation of 6-hydroxymethyl-2-(β-aminoethylthio)-1-carbadethiapen-2-em-3-carboxylic acid
02/1983
02/23/1983EP0072710A1 Carbapenem derivatives, their preparation and compositions containing them
02/22/1983US4374849 Antibiotics
02/22/1983US4374848 Administering
02/22/1983US4374772 Process for the preparation of N-formimidoyl thienamycin and reagents therefor
02/16/1983EP0072121A1 Beta-lactam antibiotics
02/16/1983EP0071908A1 1-, and 1,1-disubstituted-6-substituted-2-carbamimidoyl-1-carbadethiapen-2-em-3-carboxylic acids, a process for preparing and an antibiotic composition containing the same
02/15/1983US4374144 β-Lactam compounds, their preparation and use
02/08/1983US4372965 6-, 1- And 2-substituted-thio-1-carbadethiapen-2-em-3-carboxylic acid S-oxides
01/1983
01/18/1983US4369187 3-Substituted-1-azabicyclo[3.2.0]hept-2-en-7-one-2-carboxylic acid
01/11/1983US4368203 Antibiotics and derivatives thereof having β-lactamase inhibitory activity and production thereof
01/05/1983EP0068485A2 Novel antibiotics and process for production thereof
12/1982
12/28/1982US4366167 β-Lactam antibiotics, preparation and use
12/08/1982EP0066301A1 Intermediates for the preparation of thienamycin and process for preparing the same
12/07/1982US4362665 Thienamycins
11/1982
11/30/1982US4361512 2-Substituted thio-6-substituted-carbapen-2-em-3-carboxylic acids
11/30/1982CA1136549A1 Combination of thienamycin-type antibiotics with dipeptidase inhibitors
11/23/1982US4360684 Process for the preparation of (2S)-tetrahydro-2α-methyl-6-oxo-4βα-carboxylic acid
11/02/1982US4357342 1-Azabicyclo[3.2.0]heptan-3,7-dione-2-carboxylic acid
10/1982
10/26/1982US4356120 Intermediates for thienamycin
10/20/1982EP0062840A1 Process for the preparation of (2S)-tetrahydro-2alpha-methyl-6-oxo-4beta-amino-2H-pyran-3alpha-carboxylic acid esters
10/19/1982CA1133907A1 .beta.-LACTAM COMPOUNDS, THEIR PREPARATION AND USE
10/12/1982US4353829 Process for 5-aroylation of 1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic esters
09/1982
09/30/1982WO1982003218A1 Carba-2-penem compouns and process for their preparation
09/29/1982EP0061231A1 Process for the preparation of azabicyclo(3.2.0)-hept-2-ene derivatives
09/22/1982EP0060612A1 Process for the preparation of azabicyclo(3.2.0)-hept-2-ene derivatives
09/22/1982EP0060416A1 New beta-lactam acetic acid derivatives, the process for preparing them, and their use as intermediates for 1-azabicyclo(3.2.0.)hept-2-ene antibiotics
09/21/1982US4350703 β-Lactam antibacterial agents
09/21/1982US4350631 Antibiotics
09/15/1982EP0060077A1 Beta-lactam antibiotics, their preparation and use
09/14/1982US4349687 Intermediate for synthesis of thienamycin via (3SR, 4RS)-3-[1 (SR)-hydroxyethyl]-2-oxo-4-azetidineacetic acid
09/08/1982EP0059554A2 Beta-lactam antibiotics, a process for their preparation and their use in pharmaceutical compositions
09/08/1982EP0059478A1 Isomerisation of beta-lactam compounds and novel products obtained thereby
09/07/1982US4348320 Substituted azetidiones
09/07/1982US4348264 Photocatalyzed process for producing carbapenams and carbapen-2-ems
08/1982
08/31/1982US4347368 3-Substituted-6-substituted-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
08/31/1982US4347367 Antibiotics
08/31/1982US4347355 Inhibitors of transpeptidase
08/31/1982US4347183 Reacting a 4-substituted azedidin-2-one with an acid halide; reacting the product with a trialkyl phosphite
08/31/1982US4347181 Intermediates for producing bicyclic β-lactam-antibiotics
08/25/1982EP0058317A1 Process for the preparation of 2-penem compounds
08/17/1982US4344885 Intermediate for the preparation of thienamycin
08/11/1982EP0057565A1 Beta-lactam antibiotics, their preparation and use
07/1982
07/27/1982US4341791 6-, 2- and 1,1-Disubstituted-1-carbadethiapen-2-em-3-carboxylic acid S-oxides
07/27/1982US4341706 Process for the preparation of carbapenem antibiotics
07/27/1982US4341705 Thienamycin derivatives
07/14/1982EP0055990A1 Beta-lactam antibiotics, their preparation and use
07/14/1982EP0055929A1 Antibiotic C-19393 E5 and production thereof
06/1982
06/30/1982EP0054971A1 1-Carba-6-(1-hydroxyethyl)-2-carbonyl-penem-3-carboxylic acid, process for preparing and pharmaceutical compositions comprising the same
06/30/1982EP0054917A2 6- and 4-Substituted-1-azabicyclo(3.2.0)heptan-3,7-dione-2-carboxylates
06/29/1982US4337199 Antibiotic β-lactam compounds, production thereof, and their use as antimicrobial agent
06/10/1982WO1982001875A1 Inhibitors of transpeptidase
06/08/1982CA1125292A1 Alkylcarbopenems, their preparation, use in pharmaceutical compositions and intermediates
06/02/1982EP0053021A2 Process for 5-aroylation of 1,2-dihydro-3H-pyrrolo(1,2-a)pyrrole-1-carboxylic esters and nitriles
05/1982
05/27/1982WO1982001705A1 4-substituted-2-oxoazetidine derivatives and process for their preparation
05/26/1982EP0052299A1 2-Oxoazetidine derivatives and production thereof
05/18/1982CA1123767A1 Antibiotic ps-5 and derivatives having beta-lactamase inhibitory activity and production thereof
05/11/1982US4329481 Thienamycins, antibiotics
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