Patents
Patents for C07D 405 - Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom (69,397)
03/2005
03/03/2005CA2536095A1 Aminobenzimidazole derivatives
03/03/2005CA2535385A1 Process for the preparation of 4-amino-3-quinolinecarbonitriles
03/03/2005CA2535350A1 Acetylene derivatives as inhibitors of histone deacetylase
03/03/2005CA2533396A1 3-aryl-4-hydroxyfuranone compounds and pharmaceutical and veterinary compositions containing them
03/02/2005EP1510516A1 Pyrazole compound and medicinal composition containing the same
03/02/2005EP1509499A1 Pyrrole compounds for the treatment of prostaglandin mediated diseases
03/02/2005EP1509497A1 Calcium receptor modulating arylalkylamines
03/02/2005EP1509224A1 Methods using a combination of a 3-heteroaryl-2-indolinone and a cyclooxygenase-2 inhibitor for the treatment of neoplasia
03/02/2005EP1509218A1 Peptide deformylase inhibitors
03/02/2005EP1509213A2 Acetamides and benzamides that are useful in treating sexual dysfunction
03/02/2005EP1278741B1 Muscarinic agonists
03/02/2005EP1180102B9 Mutual prodrugs of amlodipine and atorvastatin
03/02/2005EP0871448B1 Aryl and heteroaryl quinazoline compounds which inhibit csf-1r receptor tyrosine kinase
03/02/2005CN1589260A Heterocyclic compounds and methods of use thereof
03/02/2005CN1191249C Quinoline and quinazoline compound for treating benign prostatic hyperplasia specially
03/02/2005CN1191246C Indolylpiperidine derivatives as antihistaminic and antiallergic agents
03/02/2005CN1191236C Substituted 6,6-Hetero-dicycloderivative
03/02/2005CN1191235C Process for preparign substd. pyridines compounds
03/02/2005CN1191233C N-substituted nitrogen heterocyclic compound
03/01/2005US6861530 Piperidine derivatives
03/01/2005US6861446 C7 heterosubstituted acetate taxane compositions
03/01/2005US6861432 Piperazine derivatives that destabilize androgen receptors
03/01/2005US6861424 A piperazine compound as antithrombotic agent
03/01/2005US6861419 Substituted 1, 4-thiazepine and analogs as activators of caspases and inducers of apoptosis and the use thereof
03/01/2005US6861390 3-(3-oxy-4-methoxy(pyridin-2-yl)-7-benzyl-2,6-dioxo-1,5-dioxon ane derivatives; fungicides
03/01/2005US6861389 Substituted 2-amino-1,3,5-triazines, their preparation, and their use as herbicides and plant growth regulators
03/01/2005CA2196174C Use of ketoconazole and related substances in medicaments for treatment of type ii diabetes
02/2005
02/24/2005WO2005016920A1 Pyrrole compositions useful as inhibitors of c-met
02/24/2005WO2005016914A1 Chemical compounds
02/24/2005WO2005016911A1 4-pyrimidone derivatives and their use as peptidyl peptidase inhibitors
02/24/2005WO2005016894A1 2, 4-pyrimidinediamines useful in the treatment of neoplastic diseases, inflammatory and immune system disorders
02/24/2005WO2005016893A2 2,4-pyrimidinediamine compounds for use in the treatment or prevention of autoimmune diseases
02/24/2005WO2005016892A1 Gabanergic modulators
02/24/2005WO2005016890A1 Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (vr1) receptor
02/24/2005WO2005016883A2 Acrylamide derivatives as vla-1 integrin antagonists and uses thereof
02/24/2005WO2005016879A2 Cyclic pyrazinoylguanidine sodium channel blockers
02/24/2005WO2005016862A1 Substituted arylalkanoic acid derivative and use thereof
02/24/2005WO2005016326A2 Analogs of thalidomide as potential angiogenesis inhibitors
02/24/2005WO2005005393A3 Cck-1 receptor modulators
02/24/2005WO2004099168A3 Substituted carboxylic acids
02/24/2005WO2004093789A3 Use of galr3 receptor antagonists for the treatment of depression and/or anxiety and compounds useful in such methods
02/24/2005WO2004074438A3 Ccr8 antagonists
02/24/2005WO2004046103A3 Arylpyridine compounds
02/24/2005US20050043552 Process for the synthesis of amine ethers from secondary amino oxides
02/24/2005US20050043540 such as cis-4-[[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]-N-methyl-N-(3-phenyl-2(E)-propenyl)-benzenemethanamine;
02/24/2005US20050043537 Amidation of cyanoacetic acid with an acid catalyst, condensation of the cyanoacetamide with aniline, an alcohol solvent, and a trialkylorthoformate, cyclization of the 3-amino-2-cyanoacrylamide; mild conditions; protein kinase inhibitors
02/24/2005US20050043397 Derivatives of 2-(iminomethyl)amino-phenyl, their preparation, their use as medicaments and the pharmaceutical compositions containing them
02/24/2005US20050043388 Therapy, prevention of metabolism disorders; insulin resistance; antidiabetic agents; hypoglycemic agents; anticholesterol agents; obesity; polycystic ovarian syndrome
02/24/2005US20050043370 Therapy for acquired immune deficiency or aids related complex; compound containing ketone and carboxy groups
02/24/2005US20050043364 Novel pyrrole-based HMG-CoA reductase inhibitors
02/24/2005US20050043337 Selective beta3 adrenergic agonists
02/24/2005US20050043336 Quinazoline derivatives as antitumor agents
02/24/2005US20050043330 Antiinflammation agents
02/24/2005US20050043314 Substituted alkylaminopyridazinone derivatives, process for the preparation thereof and pharmaceutical composition containing the same
02/24/2005US20050043313 1-(phenylaminocarbonylmethyl)-3-alkylamino-5,6-disubstituted-2-pyazinones; serine protease inhibitors; anticoagulants; coronary artery and cerebrovascular diseases
02/24/2005US20050043308 Process for total synthesis of ecteinascidins and intermediates therefor
02/24/2005US20050043299 Inhibitors of dipeptidyl peptidase iv
02/24/2005US20050043292 eg S)-[5-amino-6-oxo-6-(3,3,4,4-tetrafluoro-pyrrolidin-1-yl)-hexyl-carbamic acid benzylester; Type 2 diabetes, metabolic syndrome (syndrome X or insulin resistance syndrome), hyperglycemia, impaired glucose tolerance, glucosuria, metabolic acidosis, arthritis, cataracts, diabetic neuropathy
02/24/2005US20050043290 for treating neurodegenerative disease such as Alzheimer's disease
02/24/2005US20050043278 administering to a patient a hydroxy compound to treat aging, Alzheimer's Disease, cancer, cardiovascular disease, diabetic nephropathy, diabetic retinopathy, a disorder of glucose metabolism, dyslipidemia, dyslipoproteinemia, hypertension, impotence, inflammation, septicemia and syndrome X
02/24/2005US20050043248 Novel lincomycin derivatives possessing antimicrobial activity
02/24/2005US20050042771 Identifying non-drug targets; use in drug design for improving knowledge of drug-target and drug-non-target interactions, so that drug adverse reactions can be reduced or eliminated in drugs such as troglitazone, rosiglitazone, pioglitazone, methotrexate, atorvastatin, celecoxib, rofecoxib, cerivastatin
02/24/2005US20050042662 For tracing/imaging molecular transfer between cellular gap junctions
02/24/2005DE10331500A1 Neue Acridin-Derivate und deren Verwendung als Arzneimittel New acridine derivatives and their use as medicaments
02/24/2005DE102004010545A1 Pyrazoline Pyrazolines
02/24/2005CA2536470A1 Pyrrole compositions useful as inhibitors of c-met
02/24/2005CA2535665A1 Substituted arylalkanoic acid derivative and use thereof
02/24/2005CA2535619A1 4-pyrimidone derivatives and their use as peptidyl peptidase inhibitors
02/24/2005CA2535406A1 Gabanergic modulators
02/23/2005EP1508570A1 Novel physiolgically active substances
02/23/2005EP1508345A1 Absorbents and devices for the reduction of small organic compounds from blood products
02/23/2005EP1508333A1 Novel therapeutic use of riboside of 5-aminoimidazole-4- carboxamide (acadesine)
02/23/2005EP1507826A2 Amelioration of the development of cataracts and other opthalmic diseases
02/23/2005EP1507773A1 Macrocyclic compounds useful as pharmaceuticals
02/23/2005EP1507767A1 4-substituted imidazole-2-thiones and imidazol-2-ones as agonists of the alpha-2b and alpha-2c adrenergic receptors
02/23/2005EP1507761A1 Pyridine carboxamide derivatives and their use as pesticides
02/23/2005EP1507756A1 Ccr9 inhibitors and methods of use thereof
02/23/2005EP1507528A2 Methods for using jnk inhibitors for treating or preventing disease-related wasting
02/23/2005EP1286986B1 Quinolinyl-piperidin-4-ylidene-methyl-benzamide derivatives for the treatment of pain
02/23/2005EP1226128B1 New pyrimidine-2,4,6-trione derivatives, processes for their production and pharmaceutical agents containing these compounds
02/23/2005EP1177177B1 Substituted 4-oxo-quinoline-3-carboxamides: gaba brain receptor ligands
02/23/2005EP1140845B1 Susbstituted pyridine herbicides
02/23/2005EP0947507B1 Novel tetrahydrobenzindolone derivatives
02/23/2005CN1585772A Chemokine receptor antagonists and methods of use thereof
02/23/2005CN1585763A Piperidine derivatives and their use as modulators of chemokine receptor activity especially CCR5
02/23/2005CN1585755A Benzamide and heteroarylamide as P2X7 receptor antagonists
02/23/2005CN1585754A Quinazoline derivatives as antitumor agents
02/23/2005CN1585752A 4, 4-difluoro-1, 2, 3, 4-tetrahydro-5H-1-benzazepine derivatives or salts thereof
02/23/2005CN1585751A 喹啉化合物 Quinoline compound
02/23/2005CN1585749A Cannabinoid receptor ligands
02/23/2005CN1585747A Azetidinyl diamines useful as ligands of the nociceptin receptor ORL-1
02/23/2005CN1585746A Beta-amyloid protein production/secretion inhibitors
02/23/2005CN1585742A Aryl aniline beta-2 adrenergic receptor agonists
02/23/2005CN1585636A Use of endothelin receptor antagonists in the treatment of tumour diseases
02/23/2005CN1583771A Synthesis of carboxamido substituted nitrogen contained pentaheteronucleoside platinum complex
02/23/2005CN1583729A Method for synthetizing orixine and RU-19110 intermediate
02/23/2005CN1190424C Quinoline-containing Alpha-ketoamide cysteine and serine protease inhibitors
02/22/2005US6858744 Heterocyclic ester such as quinoxaline-2-carboxylic acid (4(R) -carbamoyl-1(S)-(3-fluoro-benzyl)-2(S),7-dihydroxy-7-methyl-octyl)-amide, used as preferential antagonists of macrophage inflammatory proteins
02/22/2005US6858741 Use as pesticides and herbicides
02/22/2005US6858740 2-oxo-1-pyrrolidine derivatives, process for preparing them and their uses