Patents
Patents for C07D 405 - Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom (69,397)
03/2008
03/12/2008EP1896411A2 Process for preparing renin inhibitors
03/12/2008EP1896410A1 Novel 2-azetidinone derivatives as cholesterol absorption inhibitors for the treatment of hyperlipidaemic conditions
03/12/2008EP1896023A2 Chemokine receptor binding compounds
03/12/2008EP1896021A1 Solid pharmaceutical preparation containing (r)-(-)-2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]-chroman
03/12/2008EP1896014A2 Chemical compounds
03/12/2008EP1708713B1 1-benzyl-5-piperazin-1-yl-3,4 dihydro-1h-quinazolin-2-one derivatives and the respective 1h-benzo(1,2,6)thiadiazine-2,2-dioxide and 1,4-dihydro-benzo(d)(1,3)oxazin-2-one derivatives as modulators of the 5-hydroxytryptamine receptor (5-ht) for the treatment of diseases of the central nervous system
03/12/2008EP1656355B1 Piperazine derivatives and methods of use
03/12/2008EP1560815B1 Novel pyrimidine-4,6-dicarboxamides for the selective inhibition of collagenases
03/12/2008EP1539693B1 Cannabinoid receptor agonists
03/12/2008EP1461330B1 3H-NAPHTHO[2,1-b]-PYRANE DERIVATIVES AND THEIR USE
03/12/2008EP1456657A4 Tagged microparticle compositions and methods
03/12/2008CN101142209A Pyrazinyl substituted piperazine-piperidines with cxcr3 antagonist activity
03/12/2008CN101142192A 1,2-diphenyl-imidazole derivatives and their use as CB1 receptor ligands
03/12/2008CN101142185A Indoles useful in the treatment of inflammation
03/12/2008CN101139345A Polymorphic forms of 1-'4-(5-cyanoindol-3-yl)butyl-4-(2-carbamoylbenzofuran-5-yl)piperazine hydrochloride
03/12/2008CN101139344A Method for extracting rohitukine
03/12/2008CN101139340A N-(substituted arylmethyl)-4-(disubstituted methyl)piperidines and piperazines
03/12/2008CN101139317A Organic semiconductor material containing carbazole unit and synthesis
03/12/2008CN100374435C Substd. pyridines and pyridazines with angiogenesis inhibiting activity
03/12/2008CN100374425C Aryl and heteroaryl urea CHK1 inhibitors for use as radiosensitizers and chamosensitizers
03/12/2008CN100374424C Heterocyclic amide derivative and use as pesticide
03/12/2008CN100374115C Substituted diketopiperazines as oxytocin antagonists
03/11/2008US7342120 Crystal forms of atorvastatin hemi-calcium and processes for their preparation as well as novel processes for preparing other forms
03/11/2008US7342118 Imidazole compounds for the treatment of neurodegenerative disorders
03/11/2008US7342115 Binding antagonist and arylpyridine for antiinflammatory agents, cardiovascular disorders and antagonist or agonist and for immunology
03/11/2008US7342114 4-O esters such as thymin-1-yl alkyl ester; cancer; type II DNA topoisomerase inhibition, enzyme mediated production of lethal DNA strand breaks
03/11/2008US7342027 1-phenylpiperidin-3-one derivatives and processes for the preparation thereof
03/11/2008US7342026 combining substituted quinolines with a carrier; leishmania/HIV infection; viricide, parasiticide
03/11/2008US7342019 5, 6-diaryl-pyrazine-2-amide derivatives as CB1 antagonists
03/11/2008US7341700 Method for recovery of metals from metal-containing materials using medium temperature pressure leaching
03/11/2008CA2485298C Substituted pyrazolyl compounds for the treatment of inflammation
03/11/2008CA2340230C Pyridazinone derivatives having cell adhesion inhibiting activity
03/11/2008CA2335104C Arylalkanoylpyridazines
03/11/2008CA2293382C Piperazine derivatives and their use as anti-inflammatory agents
03/11/2008CA2223535C 2,4-pentadienoic acid derivatives having retinoid-like biological activity
03/11/2008CA2192764C Integrin receptor antagonists
03/06/2008WO2008027542A2 5-substituted isoindoline compounds
03/06/2008WO2008027483A1 Benzofuran derivatives as modulators of the 5-ht2a receptor
03/06/2008WO2008027081A1 Processes for the purification of (3r,4s)-4-(4-hydroxy-protected-phenyl)-1-(4-fluorophenyl)-3-(4-fluorophenyl)-3-oxopropyl] azetidin-2-one
03/06/2008WO2008027073A1 Insecticidal n-substituted (heteroaryl)cycloalkyl sulfoximines
03/06/2008WO2008026704A1 Isoquinoline derivative
03/06/2008WO2008025886A1 Metal chelates and chelating agents containing triazolyl subunits
03/06/2008WO2008025798A1 Pyridine compounds for treating gpr119 related disorders
03/06/2008WO2008025735A1 Substituted oxindole derivatives and their use as vasopressin and/or oxytocin receptor ligands
03/06/2008WO2008006499A8 Substituted furyl sulfonylamino(thio)carbonyl triazoline(thi)ones
03/06/2008WO2007146225A3 Heterocyclic aspartyl protease inhibitors
03/06/2008WO2007144129A3 Pyrrolidine derivatives useful against diseases that depends on activity of renin
03/06/2008WO2007131201A3 Compounds and compositions as hedgehog pathway modulators
03/06/2008WO2007117607A9 Quinazolines for pdk1 inhibition
03/06/2008US20080058543 Process for making chiral 1,4-disubstituted piperazines
03/06/2008US20080058525 Novel dye complexes and use thereof in imaging members and methods
03/06/2008US20080058524 Novel dyes and use thereof in thermal imaging members and methods
03/06/2008US20080058519 Quinazoline ditosylate salt compounds
03/06/2008US20080058516 Epoxycarboxamide compound, azide compound, and amino alcohol compound, and process for preparing alpha-keto amide compound using them
03/06/2008US20080058514 ceramide-like inhibitors; novel intermediates formed during the synthesis; Glycosphingolipids
03/06/2008US20080058386 1-(4-Methoxy-benzenesulfonyl)-2,3-dihydro-1H-indol-7-ylamine; inhibiting tubulin polymerization; anticarcinogenic; mitotic arrest of microtubule structure, neovascularization; angiogenesis inhibitor: atherosclerosis, rheumatoid arthritis or Crohn's disease, diabetic retinopathy, psoriasis
03/06/2008US20080058383 Such as 2-methyl-2-(4-nitro-3-trifluoromethyl-phenylamino)-propan-1-ol; prostate cancer; cardiovascular disorders; psychological disorders
03/06/2008US20080058376 Useful in treatment of diseases through the inhibition of sodium ion flux through voltage-dependent sodium channels; treatment of central or peripheral nervous system disorders, particularly pain and chronic pain by blocking sodium channels; neuropathic pain
03/06/2008US20080058372 2,5-bis{[alkyl(or aryl)imino]aminophenyl}furans and thiophenes; "reversed" amidines; DNA-binding affinities; microbiocide; mycobacterial, fungal, protozoal infection; Mycobacterium tuberculosis, Trypanosoma spp., Candida albicans, Aspergillus spp., Cryptosporidium parvum, Giardia lamblia, Plasmodium spp.
03/06/2008US20080058359 1-[[3-[(1,4,5,6-Tetrahydro-2-pyrimidinyl)amino]phenyl]acetyl]-4-piperidinepropanoic acid; new class of selective modulator of beta 3, beta 5 or dual integrin receptors; anticarcinogenic, antiinflammatory, antidiabetic agent
03/06/2008US20080058356 2,6 Bisheteroaryl-4-Aminopyrimidines as Adenosine Receptor Antagonists
03/06/2008US20080058334 Dermatological or oncological disorders; N-(4-fluorophenyl)-N'-[4-[1-(1H-imidazol-1-yl)-2-methylpropyl]phenyl]urea for example
03/06/2008US20080058311 Antagonizing N-type calcium channels; use as analgesic, neurodegenerative diseases, brain injury, bronchial asthma, unstable angina and irritable colitis, drug withdrawal symptoms; t-butyl 2-[4-(5H-dibenzo[a,d][7]annulen-5-ylidene)-1-piperidinyl]-2-oxoethylcarbamate for example
03/06/2008US20080058304 Inhibitors of UPD-3-O (R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase, an enzyme present in gram negative bacteria; azetidine, pyrrolidine, or 3-pyrroline 2-carboxylic acid hydroxyamides; 1-(3,4-dimethoxy-5-propylbenzoyl)pyrrolidine-2R-carboxylic acid hydroxyamide for example
03/06/2008CA2670271A1 Substituted oxindole derivatives, medicinal products containing them, and use thereof
03/06/2008CA2661480A1 Insecticidal n-substituted (heteroaryl)cycloalkyl sulfoximines
03/06/2008CA2660806A1 5-substituted isoindoline compounds
03/06/2008CA2660699A1 Pyridine compounds for treating gpr119 related disorders
03/05/2008EP1894921A2 9, 10-Alpha, Alpha-Oh-Taxane analogs and methods for production thereof
03/05/2008EP1893598A1 Alkylquinoline and alkylquinazoline kinase modulators
03/05/2008EP1893588A1 Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
03/05/2008EP1893577A1 Biphenyl compounds useful as muscarinic receptor antagonists
03/05/2008EP1893576A1 Treatment of protein folding disorders
03/05/2008EP1893574A2 Peptide deformylase (pdf) inhibitors 4
03/05/2008EP1893571A2 Process for production of 4-biphenylyazetidin-2-ones
03/05/2008EP1893197A1 Chromane substituted benzimidazole derivatives as acid pump antagonists
03/05/2008EP1713797B1 1-isopropyl-2-oxo-1,2-dihydropyridine-3-carboxamide derivatives having 5-ht4 receptor agonistic activity
03/05/2008EP1633748B1 Quinoline derivatives as phosphodiesterase inhibitors
03/05/2008EP1560811B9 Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-iv (dpp-iv)
03/05/2008EP1045836B1 Pyridones as src family sh2 domain inhibitors
03/05/2008CN101137652A Pyrimidine compounds having tie2 (tek) inhibitory activity
03/05/2008CN101137648A Crystalline and amorphous 4-cyano-n-{(2r)-2-[4-(2,3-dihydro-benzo[1,4]dioxin-5-yl)-piperazin -1-yl]-propyl}-n-pyridin-2-yl-benzamide hydrochloride
03/05/2008CN101137647A Synthesis of himbacine analogs
03/05/2008CN101137645A Aryl piperazine derivatives for the treatment of neuropsychiatric disorders
03/05/2008CN101137638A Substituted aminoalkyl- and amidoalkyl-benzopyran derivatives
03/05/2008CN101137636A Exo-selective synthesis of himbacine analogs
03/05/2008CN101137622A Substituted gamma lactams as therapeutic agents
03/05/2008CN100372840C Intermediate for the preparation of epimino
03/05/2008CN100372838C Piperidine-benzenesulfonamide derivatives
03/05/2008CN100372532C Imidazolin-2-ylaminophenyl amides as IP antagonists.
03/04/2008US7339061 3-(4-oxo-4H-chromen-2-yl)-(1H)-quinolin-4-one derivatives, method for preparing same and pharmaceutical compositions containing same
03/04/2008US7339059 Benzofuran-2-yl-carbonyl- and indol-2-yl-carbonyl-trans-2,5-dimethyl-piperazine derivatives; rheumatoid arthritis, multiple sclerosis, systemic lupus erythematosus, inflammatory bowel disease, asthma; inhibit the interaction between inflammatory chemokines and their receptor
03/04/2008US7339045 High affinity for streptavidin/avidin; biotinyl moiety linked to a photoreactive group covalently bound to substrate (proteins, peptides, amino acids, lipids, cells, virus particles, fatty acids, polysaccharides)
03/04/2008US7338965 Enzyme inhibitors of beta-secretase which cleaves amyloid precursor protein present in Alzheimer's disease; Trisomy 21 (Down's Syndrome); Hereditary Cerebral Hemorrhage; cognition activators; Parkinson's disease
03/04/2008US7338959 N2-isopropyl-N5,1-dimethyl-N5-[2-({4-[(methylsulfonyl)methyl]phenyl}amino)pyrimidin-4-yl]-1H-benzimidazole-2,5-diamine; vascular endothelial growth factor (VEGF) receptor-2 and tyrosine kinase containing Ig and EGF homology domains (TIE) -2 inhibitor; antiproliferation and antihypoxic agent
03/04/2008US7338951 N-{2-[2-(3,4-Dimethoxy-phenyl)-ethoxy]-6-morpholin-4-yl-pyridin-4-yl}-N'-(1 H-indol-3-ylmethylene)-hydrazine; interleukin IL-12 overproduction-related disorder; antiinflammatory agent; autoimmune diseases: multiple sclerosis, sepsis, neuropathies, cirrhosis, hepatitis, diabetes, arthritis
03/04/2008US7338950 Amide compounds as ion channel ligands and uses thereof
03/04/2008US7338947 monocyte chemotactic proteins (MCP)-1 receptor antagonist or agonist; 2-{1-[(1,2-cis)-2-(4-Methylsulfanyl-benzoylamino)-cyclohexyl]-2-oxo-pyrrolidin-3-ylcarbamoyl}-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester; antiinflammatory agent, antiallergen; asthma, rheumatoid arthritis, atherosclerosis
03/04/2008US7338720 Organic electroluminescent element
02/2008
02/28/2008WO2008024974A1 Pyrimidine and pyrazine derivatives