Patents
Patents for C07D 405 - Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom (69,397)
01/2008
01/16/2008CN101104604A Optically pure dihydropyrimidine compounds and use for the same in preparing medicament for curing and preventing virosis
01/16/2008CN101104602A N-[(1,5-diphenyl-1H-pyrazol-3-yl)methyl]sulfamide derivative and its preparation and use
01/16/2008CN100361987C Novel ascorbic acid compounds, methods of synthesis and application use thereof
01/15/2008US7319148 Comprising reactive hydrazide function used as initial synthons for preparing compounds capable of inducing mutations or capable of inhibiting a DNA polymerase or a kinase
01/15/2008US7319132 Pendant groups linked to the polymer chain by ether, carboxyl, ester, carbamate, urea and/or amide groups; adhesives, coatings, encapsulants, and composites.
01/15/2008US7319104 hPPARs activators
01/15/2008US7318966 Luminescent element material and luminescent element comprising the same
01/15/2008CA2218479C 1,4-di-substituted piperidine derivatives
01/15/2008CA2215176C C-nucleoside derivatives and their use in the detection of nucleic acids
01/10/2008WO2008005955A2 Synthesis of heterocyclic compounds
01/10/2008WO2008005954A2 Tryphostin-analogs for the treatment of cell proliferative diseases
01/10/2008WO2008005910A2 Pyridone/hydroxypyridine 11-beta hydroxysteroid dehydrogenase type i inhibitors
01/10/2008WO2008005542A2 Antiviral phosphinate compounds
01/10/2008WO2008005348A1 Synthesis of diethyl{ i5' (3 -fluorophenyl) -pyridine-2-yl] methyl} phosphonate used in the synthesis of himbacine analogs
01/10/2008WO2008005338A1 Modulators of the histamine h3-receptor useful for the treatment of disorders related thereto
01/10/2008WO2008005262A1 Substituted bicyclic and tricyclic thrombin receptor antagonists
01/10/2008WO2008003857A1 Pyrazolylbenzimidazole derivatives, compositions containing them and use thereof
01/10/2008WO2008003665A1 Benzimidazole cannabinoid agonists bearing a substituted heterocyclic group
01/10/2008WO2008003622A1 Azolylmethyloxiranes, their use for controlling phytopathogenic fungi and agents containing said compounds
01/10/2008WO2008003607A1 Azolylmethyloxiranes, their use for controlling phytopathogenic fungi and agents containing said compounds
01/10/2008WO2008003396A1 Indazole derivatives for treating hsp90-induced diseases
01/10/2008WO2007136572A3 Antidiabetic bicyclic compounds
01/10/2008WO2007131153A3 Methods for the preparation of pyrazole-containing compounds
01/10/2008WO2007117715A3 Modulators of atp-binding cassette transporters
01/10/2008WO2007109334A3 Sip receptor modulating compounds and use thereof
01/10/2008WO2007104652A3 Non-peptidic renin inhibitors nitroderivatives
01/10/2008WO2007056389A3 Synthesis and use of novel inhibitors and inactivators of protein arginine deiminases
01/10/2008WO2007050425A3 Lxr modulators
01/10/2008US20080009632 Including N-(3,5-dichloropyrid-4-yl)-4-difluoromethoxy-8-methanesulfonamido-dibenzo[b,d]furan-1-carboxamide, starting by reacting 4-difluoromethoxy-3-hydroxybenzaldehyde with 2-bromo-1-fluoro-4-nitrobenzene; phosphodiesterase PDE IV inhibitors; anti-inflammatory treatments in airway diseases
01/10/2008US20080009531 5-Anilino-4-Heteroarylpyrazole Derivatives Useful for the Treatment of Diabetes
01/10/2008US20080009527 Inhibition of raf kinase using aryl and heteroaryl substituted heterocyclic ureas
01/10/2008US20080009524 Such as 5'-(1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-2'-methyl-N-(methylsulfonyl)biphenyl-3-carboxamide; cystic fibrosis transmembrane conductance regulator disorders
01/10/2008US20080009496 Mutagenic heterocycles
01/10/2008US20080009494 Cycloalkyl Substituted Pyrimidinediamine Compounds And Their Uses
01/10/2008US20080009493 Substituted Benzimidazoles and Imidazo-[4,5]-Pyridines
01/10/2008US20080009488 protein kinase inhibitors such as Methyl {5-[2-(5-chloro-2-methylphenyl)-1-hydroxy-3-oxo-2,3-dihydro-1H-isoindol-1-yl]-1H-benzimidazol-2-yl}carbamate, used to modulate cellular activities such as proliferation, differentiation, apoptosis, migration and chemoinvasion
01/10/2008US20080008708 Tyrosine kinase inhibitors
01/10/2008CA2656458A1 Indazole derivatives for the treatment of hsp90-induced diseases
01/10/2008CA2656265A1 Synthesis of diethyl{ i5" (3 -fluorophenyl) -pyridine-2-yl] methyl} phosphonate used in the synthesis of himbacine analogs
01/10/2008CA2655720A1 Substituted bicyclic and tricyclic thrombin receptor antagonists
01/10/2008CA2654246A1 Benzimidazole cannabinoid agonists bearing a substituted heterocyclic group
01/09/2008EP1876174A1 Quinoline and quinazoline derivatives having affinity for 5HT1-type receptors
01/09/2008EP1874762A1 Method for the production of 5-(4-[4-(5-cyano-3-indolyl)-butyl]-1-piperazinyl)-benzofuran-2-carboxamide
01/09/2008EP1874761A2 4h-1,2,4-triazin-5-one derivatives, their preparation and their use as alpha 7 nicotinic acetylcholine receptors
01/09/2008EP1874749A1 FURAN COMPOUNDS USEFUL AS EPl RECEPTOR ANTAGONISTS
01/09/2008EP1874739A1 Pharmaceutically active diazepanes
01/09/2008EP1874734A1 1h-imidiazole derivatives as cannabinoid cb2 receptor modulators
01/09/2008EP1874712A2 Preparations of 11c methyl iodide and of the radioligand 11c gb67
01/09/2008EP1874303A1 Pyrazole compounds as prostaglandin receptors ligands
01/09/2008EP1663936B1 Biaryloxymethylarene-carboxylic acids
01/09/2008EP1638934B1 3-aminopyrrolidines as inhibitors of monoamine uptake
01/09/2008EP1385845B1 N-aroyl cyclic amines
01/09/2008EP1307237B9 Complexes containing perfluoroalkyl with polar radicals, method for the production and use thereof
01/09/2008EP1239877B1 Composition comprising a tnf-alpha inhibitor and an integrin alphavbeta3 receptor antagonist
01/09/2008EP1176956B1 Carboxylic acid derivatives that inhibit the binding of integrins to their receptors
01/09/2008EP0850227B1 Pyridazin-3-one derivatives, their use, and intermediates for their production
01/09/2008CN101103026A Bicyclic heteroaryl derivatives for treating viruses
01/09/2008CN101103025A Crystals of 5-[2-amino-4-(2-furyl) pyrimidin-5-yl]-1-methylpyridin-2(1H)-one and processes for preparing the same
01/09/2008CN101103024A Pyrimidine compound crystal or amorphous form and process for producing the same
01/09/2008CN101103015A 5-thioxo-1,5-dihydro-2h-pyrrol-2-one derivatives as liver X receptor modulators
01/09/2008CN101103005A Quinazoline derivatives, preparation methods and uses thereof
01/09/2008CN101100466A Non-reversible protein tyrosine phosphorus acylase inhibitor and its preparation and application
01/09/2008CN101099740A Substituted alkylaminopyridazinone derivatives, process for the preparation thereof and pharmaceutical composition containing the same
01/09/2008CN100360523C 1,2,4 furodazole-phenoxyalkyl substituted derivative of iso-oxazole, preparation method and anti virus application
01/09/2008CN100360521C 4,4-disubstituted piperidine derivatives having CCR3 antagonism
01/09/2008CN100360514C Novel, ascorbic acid compounds, methods of synthesis and application use thereof
01/09/2008CN100360507C Inhibition of raf kinase using substituted heterocyclic ureas
01/09/2008CN100360505C Quinazoline derivatives as angiogenesis inhibitors
01/09/2008CN100360499C Propanoic acid derivatives that inhibit binding of integrins to their receptors
01/09/2008CN100360130C 1-(4-piperidinyl) benzimidazolones as histamine H3 antagonists
01/08/2008US7317107 Imidazole 4-carboxamide compounds with adenosine deaminase inhibiting activity
01/08/2008US7317102 Diarylmethyl and related compounds
01/08/2008US7317032 Imidazolyl inhibitors of 15-lipoxygenase
01/08/2008US7317031 3-(SO2-substituted anilino)-5-amino-1-((hetero)aryl-carbonyl- or sulfonyl)-1H-1,2,4-triazoles: 4-[[5-amino-1-[(3-methyl-2-thienyl)carbonyl]-1H-1,2,4-triazol-3-yl]amino]-benzenesulfonamide; for treating melanoma; cervical, ovarian and prostate adenocarcinoma; colon carcinoma and breast cancer
01/08/2008US7317028 Antitumor agents; autoimmune disease; skin disorders; anticancer agents
01/08/2008US7317026 Sleep disorders; side effect reduction ; antihistamine antagonist
01/08/2008US7317022 3-isopropyl-2-oxo-2,3-dihydrobenzoimidazole-1-carboxylic acid [(1S,3R,5R)-8-((S)-2-hydroxy-3-methylamino-propyl)-8-azabicyclo[3.2.1]oct-3-yl]-amide; bioavailability upon oral administration; medical conditions mediated by 5-HT4 receptor activity
01/08/2008US7317013 such as N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-{4-[1-(2-hydroxyethyl)piperidin-4-yl]butyl} guanidine dihydrochloride and optionally with g-coupled receptor agonist or bronchodilators, used for promoting hydration of mucosal surfaces; improved pharmacokinetics
01/08/2008CA2225830C Dialkyl phenyl halide-substituted keto-enols for use as herbicides and pesticides
01/08/2008CA2172513C Aminocyclohexylesters and uses thereof
01/03/2008WO2008002974A1 Pyrrole derivatives and their methods of use
01/03/2008WO2008002245A2 Imidazol-pyrimidine derivatives for treatment of diseases related to glycogen synthase kinase (gsk3)
01/03/2008WO2008002244A2 Imidazol-pyrimidine derivatives for treatment of diseases related to glycogen synthase kinase (gsk3)
01/03/2008WO2008000645A1 Tetrazole-substituted arylamides
01/03/2008WO2007125331A3 Amino-ethyl-amino-aryl (aeaa) compounds and their use
01/03/2008WO2007122333A3 Process for preparing disulphides and thiosulphinates and compounds prepared
01/03/2008WO2007120729A3 Pyridyl amide t-type calcium channel antagonists
01/03/2008WO2007117961A3 Renin inhibitors
01/03/2008WO2007089626A3 Anabaseine derivatives, pharmaceutical compositions and methods of use thereof
01/03/2008WO2007054978A3 Process for preparing paroxetine hydrochloride hemihydrate
01/03/2008WO2005019200A3 Aryl piperidine derivatives as vla-1 integrin antagonists and uses thereof
01/03/2008US20080004449 Synthesis of diethyl{[5-(3-fluorophenyl)-pyridine-2yl]methyl}phosphonate
01/03/2008US20080004331 for hepatitis C; histone deacetylase inhibitors; N-hydroxy-4-{[(naphthyl-carbonylamino]alkoxy}benzamides; anticarcinogenic agent; acute promyelocytic leukemia; cell-cycle arrest in late G1 phase or at the G2/M transition
01/03/2008US20080004330 Aminomethyl-Azacycle Derivatives as Inhibitors of Monoamine Uptake
01/03/2008US20080004318 Substituted Bicyclic and Tricyclic Thrombin Receptor Antagonists
01/03/2008US20080004294 Heterocyclic compounds
01/03/2008US20080004288 Indazole Sulphonamide Derivatives
01/03/2008US20080004278 (1-phenyl-5-propyl-1H-pyrazol-4-yl)-(3-amino-N-cyclopropyl-4-methyl-benzamide)-amine; p38 mitogen-activated protein kinase inhibitor; reduced levels of TNF- alpha expression; antiinfammatory agent: rheumatoid arthritis, psoriasis, multiple sclerosis, endotoxin shock, osteoporosis, Alzheimer's disease
01/03/2008US20080004275 Antiviral 4-Aminocarbonylamino-Substituted Imidazole Compounds
01/03/2008US20080004268 e.g. 4-tert-Butyl-N-[3-phenyl-2-(pyrrolidine-1-carbonyl)-1H-indol-5-yl]-benzenesulfonamide; contraceptive; for male fertility control; act on testicular stem cells and mature sperm