Patents
Patents for C07D 405 - Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom (69,397)
03/2008
03/20/2008WO2008033931A1 Para-xylylene carboxylic acids and isothiazolones useful as protein tyrosine phosphatases (ptps) in particular ptp-ib
03/20/2008WO2008033854A1 Certain substituted amides, method of making, and method of use thereof
03/20/2008WO2008033793A2 Synthesis of methyl nonactate derivatives
03/20/2008WO2008033567A1 N-methylaminomethyl isoindole compounds and compositions comprising and methods of using the same
03/20/2008WO2008032171A1 Dibenzofuran derivatives as inhibitors of pde-4 and pde-10
03/20/2008WO2008005910A3 Pyridone/hydroxypyridine 11-beta hydroxysteroid dehydrogenase type i inhibitors
03/20/2008WO2007139960A3 Compounds that modulate hsp90 activity and methods for identifying same
03/20/2008US20080070972 for an oral cytokine inhibitor of interleukin-1 beta converting enzyme; antiinflammatory agent: rheumatoid arthritis and psoriasis; wet granulated compound with the organic solvent, a first and second binding agent, porous agent, glidant, lubricant
03/20/2008US20080070951 Viricides; HIV antivirals effective against problematic drug escape mutants; N-[(1S,1aR,7bR)-4,7-difluoro-1,1a,2,7b-tetrahydrocyclopropa[c]chromen-1-yl]-N'-[5-(4-(sulfonamido)phenoxy)-2-pyridinyl]urea
03/20/2008US20080070945 4-(2-methyl-5,6,7,8-tetrahydro-quinolin-7-ylmethyl)-1,3-dihydro-imidazole-2-thione as specific alpha2b agonist and methods of using the same
03/20/2008US20080070916 Treating disorders such as proliferative diseases, and cancer; compounds can act as probes of biological function; libraries; for example, 2-ethoxy-3-(2-hydroxyethoxyethoxyethyl)-4-(1-acetylindol-3-yl)-6-(morpholinocarbonyl)-2H-3,4-dihydropyran
03/20/2008US20080070915 Poly(ADP-ribose)polymerase (PARP); ischemia, reperfusion injuries, neurological disorders, neuroprotectants, sensitizer for chemotherapy or radiotherapy, anticancer
03/20/2008US20080070906 Quinolinone derivatives
03/20/2008US20080070902 Cinnamide Compound
03/20/2008US20080070869 Malonyl-CoA Decarboxylase Inhibitors Useful as Metabolic Modulators
03/20/2008DE102007037830A1 Indolinsulfonamidverbindungen Indolinsulfonamidverbindungen
03/20/2008CA2663376A1 N-methylaminomethyl isoindole compounds and compositions comprising and methods of using the same
03/20/2008CA2663189A1 Benzimidazolone derivatives
03/20/2008CA2663178A1 Dibenzofuran derivatives as inhibitors of pde-4 and pde-10
03/20/2008CA2663113A1 Nicotinic acid derivatives as modulators of metabotropic glutanate receptors
03/20/2008CA2661654A1 Certain substituted amides, method of making, and method of use thereof
03/19/2008EP1900732A1 Novel nitrogenated heterocyclic compound and salt thereof
03/19/2008EP1899324A2 Benzimidazole-carboxamide compounds as 5-ht4 receptor agonists
03/19/2008EP1899322A1 Isoquinoline derivatives as inhibitors of rho-kinase
03/19/2008EP1899299A2 C-linked cyclic antagonists of p2y1 receptor useful in the treatment of thrombotic conditions
03/19/2008EP1898905A2 Hydroisoindoline tachykinin receptor antagonists
03/19/2008EP1824338B1 3-cyclopropyl-4-(3-amino-2-methylbenzoyl)pyrazols and the use of the same as herbicides
03/19/2008EP1660487B1 Pyrrole compositions useful as inhibitors of c-met
03/19/2008EP1646613B1 Quinoline and quinazoline derivatives having affinity for 5ht1-type receptors
03/19/2008EP1562933B1 Substituted amine derivatives and methods of use in the treatment of angiogenesis related disorders
03/19/2008EP1532132B1 Novel benzodioxoles
03/19/2008EP1499316B1 (1-4-piperidinyl)benzimidazole derivatives useful as histamine h3 antagonists
03/19/2008EP1458380B1 Cis-2,4,5- triphenyl-imidazolines and their use in the treatment of tumors
03/19/2008EP1303496B9 Pyrimidine derivatives
03/19/2008EP1149091B1 4-(heterocyclylsulfonamido)-5-methoxy-6-(2-methoxyphenoxy)-2-phenyl- or pyridylpyrimidines as endothelin receptor antagonists
03/19/2008EP1042293B1 Substituted pyridine and pyridazine compounds and their pharmaceutical use
03/19/2008CN101146799A Cgrp-antagonists, process for their preparation as well as their use as medicaments
03/19/2008CN101146798A Novel heterocyclic benzo[C]chromene derivatives useful as modulators of the estrogen receptors
03/19/2008CN101146797A 4-2-(cycloalkylamino)pyrimidin-4-YL!- (phenyl)- imidazolin-2-one derivatives as p38 map-kinase inhibitors for the treatment of inflammatory diseases
03/19/2008CN101146786A Piperazinyl and piperidinyl ureas as modulators of fatty acid amide hydrolase
03/19/2008CN101146769A Azolylacylguanidines as beta-secretase inhibitors
03/19/2008CN101146530A 3, 4-substituted pyrrolidine derivatives for the treatment of hypertension
03/19/2008CN101143864A Novel triazolo pyrimidine compounds
03/18/2008US7345175 Biphenyl derivatives
03/18/2008US7345090 Galenical formulation
03/18/2008US7345085 Indoles having anti-diabetic activity
03/18/2008US7345079 Treatment of disorder related to low cyclic GMP levels
03/18/2008US7345077 4-(substituted cycloalkylmethyl) imidazole-2-thiones, 4-(substituted cycloalkenylmethyl) imidazole-2-thiones, 4- (substituted cycloalkylmethyl) imidazol-2-ones and 4- (substituted cycloalkenylmethyl) imidazol-2-ones and related compounds
03/18/2008US7345064 5-(4-pyridyl)valeric acid N-[2-(1-adamantyl)ethyl]-N-pentylamide; Autoimmune diseases such as rheumatoid arthritis, allergy and diabetes
03/18/2008US7345059 Diphenylpyridine derivatives, preparation and therapeutic application thereof
03/18/2008US7345054 Heterocyclic inhibitors of ERK2 and uses thereof
03/18/2008US7345052 Arylindenopyridines and arylindenopyrimidines and related therapeutic and prophylactic methods
03/18/2008US7345051 For controlling mucin over-production associated with diseases such as chronic obstructive pulmonary diseases including asthma and chronic bronchitis, inflammatory lung diseases, cystic fibrosis and acute or chronic respiratory infections
03/18/2008US7345044 Sodium channel blockers
03/18/2008US7344701 For conjugation with biomolecules, drugs, and toxins
03/18/2008CA2277893C 4-(3-heterocyclyl-1-benzoyl)pyrazoles and their use as herbicides
03/18/2008CA2206125C N-substituted hydrazinophenylsulphonylureas, as herbicides and plant growth regulators
03/13/2008WO2008030448A1 Phenethylamide derivatives with kinase inhibitory activity
03/13/2008WO2008029924A1 Cyclic aminoalkylcarboxamide derivative
03/13/2008WO2008029876A1 Salt of 5-[2-amino-4-(2-furyl)pyrimidin-5-yl]-1- methylpyridin-2(1h)-one and crystal thereof
03/13/2008WO2008029825A1 Imidazole derivative
03/13/2008WO2008029257A2 Improved method for preparing 1,3-disubstituted pyrrolidine compounds
03/13/2008WO2008028691A1 N-(1-hetarylpiperidin-4-yl)(het)arylamides as ep2 receptor modulators
03/13/2008WO2008028624A1 Fungicides
03/13/2008WO2007148185A3 Substituted 3 -amino- pyrrolidino-4 -lactams as dpp inhibitors
03/13/2008WO2007146376A3 Substituted 3-cyanopyridines as protein kinase inhibitors
03/13/2008WO2007136302A8 Active substances, pharmaceutical composition and a method for the production and use thereof
03/13/2008WO2007136116A3 C-phenyl glycitol compound for the treatment of diabetes
03/13/2008WO2007135527A3 Benzimidazolyl compounds
03/13/2008WO2007123939A8 Novel arylamino n-heteraryls as mek inhibitors
03/13/2008US20080064873 Oxidizing an amino alcohol (obtained by ring opening the epoxy, aziding, reducing and reacting it with a carboxylic acid); stereoselectivity; protease inhibitors: antiallergens; anticarcinogenic and hypotensive agents
03/13/2008US20080064726 Dipeptidyl peptidase-IV (DPP-IV) inhibitor; diabetes mellitus, insulin-resistant diseases, obesity, hypoglycemia ; 2-[4-({2-[(2S,4S)-2-cyano-4-fluoropyrrolidin-1-yl]-2-oxoethyl}amino)-4-methylpiperdin-1-yl]-2-oxoethyl acetate monofumarate
03/13/2008US20080064720 Very Late Antigen-4 dependent inflammatory disease; asthma, allergic rhinitis, sinusitis, conjunctivitis, food allergy, inflammatory skin disorders, autoimmune disorders, or atherosclerosis, inflammatory skin disorder; methyl 3-[2-(2,6-dichlorophenyl)-6-quinolinyl]-2-hydroxy-2-propenoate
03/13/2008US20080064706 Piperidine Derivatives as Histamine H3 Receptor Ligands
03/13/2008US20080064704 1,4-Diaryl-Dihydropyrimidin-2-Ones and Their Use as Human Neutrophil Elastase Inhibitors
03/13/2008US20080064700 Aryl triazines as LPAAT-beta inhibitors and uses thereof
03/13/2008US20080064695 Neuronal nicotinic acetylcholine receptor modulators; such as ethyl 1-[4-(aminosulfonyl)phenyl]-5-(4-bromophenyl)-2-methyl-1H-pyrrole-3-carboxylate
03/13/2008US20080064690 Neuropathic or inflammatory pain relief; inhibiting ion flux through channel including PN3 subunit; potency
03/13/2008US20080064679 Water Soluble Cannabinoids
03/13/2008US20080064677 S1P receptor modulating compounds and use thereof
03/13/2008US20080064661 Dihydroxyl compounds and compositions for cholesterol management and related uses
03/13/2008CA2662839A1 Improved method for preparing 1,3-disubstituted pyrrolidine compounds
03/13/2008CA2662281A1 N-(1-hetarylpiperidin-4-yl)(het)arylamides as ep2 receptor modulators
03/13/2008CA2662259A1 Fungicides
03/13/2008CA2662112A1 Imidazole derivatives and their use as cannabinoid type 2 (cb2) receptor modulators
03/12/2008EP1897878A1 Stable crystal of protected pseudouridine
03/12/2008EP1896467A2 Tricyclic opioid modulators
03/12/2008EP1896460A1 Benzofuranyl derivatives as 5-ht6-receptor inhibitors
03/12/2008EP1896459A1 Novel 2-azetidinone derivatives as cholesterol absorption inhibitors for the treatment of hyperlipidaemic conditions
03/12/2008EP1896458A1 New 2-azetidinone derivatives as cholesterol absorption inhibitors for the treatment of hyperlipidaemic conditions
03/12/2008EP1896457A1 New 2-azetidinone derivatives useful in the treatment of hyperlipidaemic conditions
03/12/2008EP1896456A2 Novel tetracyclic tetrahydrofuran derivatives containing a cyclic amine side chain
03/12/2008EP1896454A1 AMlNO-5-(5-MEMBERED)HETEROARYLIMIDAZOLONE COMPOUNDS AND THE USE THEREOF FOR -SECRETASE MODULATION
03/12/2008EP1896453A1 Carbon-linked substituted piperidines and derivatives thereof useful as histamine h3 antagonists
03/12/2008EP1896448A1 AMINO-5-(6-MEMBERED)HETEROARYLIMIDAZOLONE COMPOUNDS AND THE USE THEREOF FOR ß-SECRETASE MODULATION
03/12/2008EP1896438A1 Phenyl-pyrazole derivatives as non-steroidal glucocorticoid receptor ligands
03/12/2008EP1896428A1 Pyrimidine derivatives for the treatment op gaba b mediated nervous system disorders
03/12/2008EP1896422A2 Tyrosine kinase inhibitors
03/12/2008EP1896421A2 Benzocycloheptapyridines as inhibitors of the receptor tyrosine kinase met
03/12/2008EP1896417A1 Linear urea mimics antagonists of p2y1 receptor useful in the treatment of thrombotic conditions