Patents for C07D 295 - Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms (34,005) |
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03/23/1999 | US5886024 Thiophene-containing butonic acid derivatives as matrix metalloprotease inhibitors |
03/23/1999 | US5885999 Treatment or prevention of pain, inflammation, migraine, emesis and postherpetic neuralgia |
03/23/1999 | US5885990 Fibrinolysis promoting action; thrombolysis action |
03/23/1999 | US5885985 Antiinflammatory agents |
03/23/1999 | US5885984 Blockade of ion channels and the treatment of arrhythmias. |
03/23/1999 | CA2092794C Naphthylalkylamines, process for their preparation and pharmaceutical compositions that contain them |
03/18/1999 | WO1999012889A1 Quaternary ammonium phosphate compound and method of preparing the same |
03/18/1999 | WO1999012877A1 Enantioselective reduction of ketones with a silane agent/metal compound/chiral ligand system |
03/18/1999 | CA2298533A1 Reduction enantioselective de cetones avec un systeme agent silanique/compose metallique/ligand chiral |
03/17/1999 | EP0902014A1 Process for producing aryl carbamates |
03/17/1999 | EP0901469A1 Arylalkylpiperazine compounds as antioxidants |
03/16/1999 | US5883257 N-piperidinyl- and N-tetrahydropyridinyl-2-anthracenecarboxamides: dopamine receptor subtype specific ligands |
03/16/1999 | US5883096 Di-n-substituted piperazine derivatives; alzheimer*s disease, cognition activators; synergistic mixtures with acetylcholinesterase inhibitors |
03/16/1999 | US5883092 Pyrimidine derivatives as endothelin antagonists |
03/16/1999 | CA2158108C Compositions containing sertraline and a 5-ht1d receptor agonist or antagonist |
03/16/1999 | CA2146906C Reductive amination catalysts |
03/11/1999 | WO1999011608A1 Malonic acid based matrix metalloproteinase inhibitors |
03/11/1999 | WO1999011606A2 Inhibitors of protein tyrosine phosphatase |
03/11/1999 | WO1999011258A1 Lymphocyte function antigen-1 antagonists |
03/11/1999 | WO1998056771A3 Piperazine derivatives and their use as anti-inflammatory agents |
03/11/1999 | CA2302037A1 Malonic acid based matrix metalloproteinase inhibitors |
03/11/1999 | CA2298601A1 Inhibitors of protein tyrosine phosphatase |
03/10/1999 | EP0900190A1 Novel acetals of hydroxy carboxylic acids, derivatives thereof and process for the preparation thereof |
03/09/1999 | US5880151 Treating or preventing disease characterized by high levels of low density lipoprotein particles or cholesterol in blood |
03/09/1999 | US5880147 Amide derivatives having ACAT inhibitory activity, their preparation and their therapeutic and prohylactic use |
03/09/1999 | US5880120 Treating depression by administering an antidepressant |
03/09/1999 | US5879681 Compounds and compositions for delivering active agents |
03/04/1999 | WO1999010316A1 3-amidinoaniline derivatives, activated blood coagulation factor x inhibitors, and intermediates for producing both |
03/04/1999 | WO1999010313A1 N-aroylphenylalanine derivatives |
03/04/1999 | WO1999010312A1 N-alkanoylphenylalanine derivatives |
03/04/1999 | CA2301559A1 3-amidinoaniline derivatives, activated blood coagulation factor x inhibitors, and intermediates for producing both |
03/04/1999 | CA2300121A1 N-alkanoylphenylalanine derivatives |
03/03/1999 | EP0899268A2 Process for the preparation of omeprazole and intermediate compounds |
03/03/1999 | EP0898567A1 Novel n-aminoalkyl-1-biphenylenyl-2-carboxamides; new dopamine receptor subtype specific ligands |
03/03/1999 | CN1209803A Conformationally restricted aromatic inhibitors of microsomal triglyceride transfer protein and method therefor |
03/03/1999 | CN1209754A Perfluoroalkyl-containing metal complexes, its preparing method and use in NMR diagnostics |
03/02/1999 | US5877342 Skin disorders; respiratory system disorders; cardiovascular disorders |
03/02/1999 | US5877317 Heterocyclic compounds for the treatment of CNS and cardiovascular disorders |
03/02/1999 | US5877315 Dimeric N-Alkyl ammonium acetonitrile bleach activators |
03/02/1999 | US5877219 Non-steroidal ligands for the estrogen receptor |
03/02/1999 | US5877203 Treatment for atherosclerosis and other cardiovascular and inflammatory diseases |
03/02/1999 | US5876710 Drug delivery; using a brominated benzamide compound |
03/02/1999 | CA2117250C Alkoxyphenylalkylamine derivatives |
02/25/1999 | WO1999009015A1 2-{3-[4-(2-t-butyl-6- trifluoromethylpyridin-4-yl) piperazin-1-yl] propylmercapto} pyrimidin-4-ol-fumarate |
02/25/1999 | WO1999009002A1 Phenol derivatives |
02/25/1999 | WO1999009000A2 Novel inhibitors of aggrecanase and matrix metalloproteinases for the treatment of arthritis |
02/25/1999 | DE19837386A1 New CCR-3 antagonist piperazine derivatives and analogues |
02/25/1999 | CA2301297A1 2-{3-[4-(2-t-butyl-6- trifluoromethylpyridin-4-yl) piperazin-1-yl] propylmercapto} pyrimidin-4-ol-fumarate |
02/25/1999 | CA2301038A1 Novel inhibitors of aggrecanase and matrix metalloproteinases for the treatment of arthritis |
02/24/1999 | EP0897382A1 Alkoxy acetic acid derivatives |
02/24/1999 | EP0800541B1 Siloxane-containing networks |
02/24/1999 | CN1209124A Novel compounds with analgesic effect |
02/23/1999 | US5874616 Preparation of bis (fluoroalkylenesulfonyl) imides and (fluoroalkysulfony) (fluorosulfonyl) imides |
02/23/1999 | US5874530 Cyclic depsipeptide sulfonylation, sulfenylation and phosphorylation process |
02/23/1999 | US5874473 Substituted cycloalkanecarboxylic acid derivatives as matrix metalloprotease inhibitors |
02/23/1999 | US5874434 10,11-methanodibenzosuberane derivatives |
02/18/1999 | WO1999007689A1 Aniline derivatives as calcium channel blockers |
02/18/1999 | WO1999007672A1 Derivatives of 2,5- and 3,5-disubstituted anilines, their preparation and use |
02/18/1999 | WO1999007668A1 Non-steroidal ligands for the estrogen receptor |
02/18/1999 | WO1999007666A1 Amine derivatives and process for producing the same |
02/18/1999 | WO1999007377A1 1-[4-(substituted alkoxy)benzyl]naphthalene compounds having estrogen inhibitory activity |
02/18/1999 | DE19735410A1 New stable fumarate salt of pyrimidinol derivative dopamine D3 receptor ligand, having improved solubility and suitable for oral administration |
02/18/1999 | CA2300273A1 Amine derivatives and method for producing the same |
02/18/1999 | CA2298651A1 1-¬4-(substituted alkoxy)benzyl|naphthalene compounds having estrogen inhibitory activity |
02/18/1999 | CA2245043A1 Ccr-3 receptor antagonists |
02/17/1999 | EP0896590A1 Rapid purification by polymer supported quench |
02/17/1999 | EP0896533A2 Pentafluorobenzenesulfonamides and analogs |
02/17/1999 | CN1208409A Novel benzoyl guanidine derivatives process for their preparation and their use in the preparation of medicines |
02/16/1999 | US5872256 Cyclobutenedione derivative, process for preparing the same, and nonlinear optical element |
02/16/1999 | US5872138 Thrombin inhibitors |
02/16/1999 | US5872125 Polymorphs of lesopitron dihydrochloride and its hydrated forms, preparation processes and compositions containing it |
02/16/1999 | US5872119 2-Naphthamide derivatives and their therapeutic applications |
02/16/1999 | US5872118 Relaxation of skeletal muscle in spastic, hypertonic and hyperkinetic conditions |
02/16/1999 | US5872117 Treating cerebrovascular dementia, senile dementia, alzheimer's dementia, sequelae of ischemic encephalopathy and cerebral apoplexy |
02/16/1999 | US5872115 Compounds for treatment of hypercholesterolemia, ischemic heart disease, cerebrovascular disease or atherosclerosis |
02/11/1999 | WO1999006384A1 1-(n-phenylaminoalkyl)-piperazine derivatives substituted at position 2 of the phenyl ring |
02/11/1999 | WO1999006383A1 Piperazine derivatives active on the lower urinary tract |
02/11/1999 | WO1999006381A1 A crystalline dibenzothiazepine derivative and its use as an antipsychotic agent |
02/11/1999 | WO1999006351A1 Process for converting propargylic amine-n-oxides to enaminones |
02/11/1999 | WO1999006340A2 Sulfonylamino substituted hydroxamic acid derivatives as metalloprotease inhibitors |
02/11/1999 | CA2298617A1 Acyclic metalloprotease inhibitors |
02/11/1999 | CA2298595A1 Process for converting propargylic amine-n-oxides to enaminones |
02/11/1999 | CA2297095A1 1-(n-phenylaminoalkyl)-piperazine derivatives substituted at position 2 of the phenyl ring |
02/10/1999 | EP0895993A1 Process for the preparation of N-aryl-N'aklyl-piperazines |
02/10/1999 | EP0895989A1 1-[4-(Substituted alkoxy)benzyl] naphthalene compounds having estrogen inhibitory activity |
02/10/1999 | EP0895988A1 Arylsulfonylamino hydroxamic acid derivatives |
02/10/1999 | CN1207734A Metalloproteinase inhibitors, pharmaceutical compositions contg. them and their pharmaceutical uses, and methods and intermediates useful for their preparation |
02/10/1999 | CN1042029C 1,4-di(phenylalkyl) piperizine deriv. and pharmaceutical composition contg. same |
02/09/1999 | US5869661 Condensing a 6-fluoroquinolonecarboxylic acid with a saturated heterocyclic amine with or without a solvent |
02/09/1999 | US5869655 Diamine compounds, methods of making same, method of use of same and intermediates |
02/09/1999 | US5869484 Treating diseases derived by acetylcholine deficiency; alzheimer*s disease |
02/04/1999 | WO1999005134A1 Substituted 1,2,3,4-tetrahydronaphthalene derivatives |
02/04/1999 | WO1999005133A1 Benzamide cycloalkyl stimulating high and low gastrointestinal motricity |
02/04/1999 | WO1999005096A2 Urokinase inhibitors |
02/04/1999 | WO1999005095A1 Aminocycloalkane compounds |
02/04/1999 | WO1999005093A1 Isocyanoalkyl carbonic acid derivatives, their conversion into secondary amidoalkyl carbonic acid derivatives by isocyanide-multicomponent reactions, as well as these secondary amidoalkyl carbonic acid derivatives. |
02/04/1999 | WO1999005091A1 Novel compound having effect of promoting neuron differentiation |
02/04/1999 | WO1999004796A1 Fibrinogen receptor antagonists |
02/04/1999 | WO1999004794A1 Cyclic amine modulators of chemokine receptor activity |
02/04/1999 | WO1999004778A1 Pharmaceutical compounds |