Patents
Sitemap › C07 - Organic chemistry › C07D - Heterocyclic compounds › C07D 281 - Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
Patents for C07D 281 - Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms (1,924)
04/2009
04/28/2009CA2259922C Calcium receptor active compounds
04/23/2009US20090105215 Heterocyclic compounds, methods for the preparation thereof, and uses thereof
04/15/2009EP2046739A1 Substituted aniline derivatives
04/14/2009US7517910 Alkoxyphenylpropanoic acid derivatives
04/09/2009US20090093459 2-alkoxy-3,4,5-trihydroxyalkylamide-benzothiazepines preparation thereof, compositions containing them and use thereof
03/2009
03/26/2009WO2008121415A3 Improved process for preparing quetiapine fumarate
03/26/2009WO2005084295A3 Fused heterotricyclic compounds as inhibitors of 17b-hydroxysteroid dehydrogenase 3
03/24/2009US7507816 Compounds for treatment of inflammation, antidepressants, nervous system disorders, cardiovascular disorders or analgesics from mannich reaction
03/19/2009US20090075973 Benzo-fused heterocycles
03/18/2009EP2035400A1 Methods for the preparation of salts of 2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxyl]ethanol (quetiapine) and for the purification thereof
03/18/2009CN101389615A Process for preparing dibenzothiazepine compounds
03/04/2009EP1781646A4 Process for the preparation of 11-(4-[2-(2-hydroxyethoxy)ethyl]-i-piperazinyl)dibenzo[b,f][1,4]thiazepine
02/2009
02/25/2009EP1907370B1 Novel 1,4-benzothiazepine-1,1-dioxide derivative having improved properties, method for the production thereof, medicaments containing said compound, and use thereof
02/25/2009EP1694658B1 Method for the production of a thiazolo [3,4,5-de] [4,1]benzothiazepine-type product
02/25/2009CN100463904C Process for preparing diltiazem intermediate
02/10/2009US7488821 heating quetiapine fumarate until it melts either at normal pressure or at reduced pressure, followed by cooling till it solidifies
02/04/2009CN101360725A Solid formulations
02/04/2009CN101360724A Salt forms
01/2009
01/21/2009EP0951466B1 Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds
01/15/2009WO2008140592A3 Radioactively labeled 1,4-benzothiazepines and methods of screening for compounds that bind ryanodine receptors
01/08/2009WO2007024717A3 Agents for preventing and treating disorders involving modulation of the ryr receptors
01/07/2009CN101337948A 1,5-benzothiazepines compounds, preparation method and application thereof
12/2008
12/18/2008WO2008152434A1 Synthesis for the preparation of quetiapine
12/18/2008WO2008036139A3 Inhibitors of mshc and homologs thereof, and methods of identifying same
12/11/2008US20080306041 Cardiovascular Compounds Comprising Heterocyclic Nitric Oxide Donor Groups, Compositions and Methods of Use
12/10/2008EP2000141A1 Methods for preparing crystalline quetiapine hemifumarate
12/03/2008EP1996568A2 Process for preparing dibenzothiazepine compounds
12/03/2008EP1996202A1 Chemical compounds
11/2008
11/27/2008US20080293678 Organic Nitric Oxide Donor Salts of Angiotensin Converting Enzyme Inhibitors, Compositions and Methods of Use
11/20/2008WO2008140592A2 Radioactively labeled 1,4-benzothiazepines and methods of screening for compounds that bind ryanodine receptors
11/20/2008WO2008021439A3 Compositions and methods for treatment of cardiac hypertrophy
11/06/2008WO2008133273A1 Pharmaceutical composition for treatment of alzheimer's disease
10/2008
10/29/2008CN101293879A Method for preparing quetiapin
10/23/2008US20080261948 Ligands for G-Protein Coupled Receptors
10/14/2008CA2497345C Novel quaternary ammonium compounds
10/09/2008WO2008121415A2 Improved process for preparing quetiapine fumarate
09/2008
09/18/2008WO2007104933A8 Chemical compounds
09/12/2008WO2008109577A1 Polymorphs of 7-[(3-chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoic acid s,s dioxide and methods of making and using the same
09/12/2008CA2679936A1 Polymorphs of 7-[(3-chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoic acid s,s dioxide and methods of making and using the same
09/11/2008US20080221081 Polymorphs of 7-[(3-chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoic acid s,s dioxide and methods of making and using the same
09/11/2008US20080220048 implantable medical equipment coated with biocompatible polymers based on modified [1,4]oxazepan-7-one, used as in situ time-release agents or drug delivery devices; prevention of restenosis, aneurysms and plaque
09/02/2008US7420051 Antitumor agents; microbiocides; antibiotics; forming a 1,4 bridge using a 1-labile, 10-hydroxy, 18-protected hydroxyl, di-6,8-en-5-one fused ring compound. After formation of the 1,4 brige, C-18 protection is removed before spiroamine introduction
08/2008
08/28/2008WO2008102908A1 Haloalkylsulfonanilide derivative
08/28/2008US20080207592 Novel 1,4-benzothiazepine-1,1-dioxide derivative having improved properties, method for the production thereof, medicaments containing said compound, and use thereof
08/26/2008US7417040 hormone sensitive diseases such as prostate hypertrophia, benign prostatic hyperplasia, adenomas and neoplasies of the prostate, prostate cancer, hirsutism, and polycystic ovary syndrome; dibenz[b,f]azocine, dibenzo[b,f][1,4]thiazocine, dibenz[b,f][1,5]oxazocine derivatives; anticancer, antitumor agents
08/12/2008US7411095 obtained using specific secondary amines are unexpectedly stable against water; reacting an aldehyde or ketone with an amine and treating the resulting reaction mixture with an acidic aqueous solution
08/06/2008EP1951694A2 Salt forms
08/06/2008EP1951693A2 Solid formulations
07/2008
07/30/2008EP1948628A1 Quetiapine hemifumarate purification by crystallization
07/24/2008US20080176830 Compounds, Compositions, and Methods
07/17/2008US20080171869 Condensation of 10H-dibenzo-[b,f][1,4]-thiazepin-11-one with a piperazine derivative in the presence of a titanium alkoxide catalyst; Titanium catalyst easier to handle, have low toxicity, not chlorinated, much less harmful for the environment
07/16/2008CN101223151A 1,4-benzothiazepine 1,1-dioxide derivative, process for its preparation, medicaments comprising this compound, and use thereof as a hypolipidaemic
07/09/2008EP1942105A1 Aminodihydrothiazine derivative
07/09/2008EP1276729B1 New neurokinin antagonists for use as medicaments
07/09/2008CN101218217A Novel 1,4-benzothiazepine-1,1-dioxide derivative having improved properties, method for the production thereof, medicaments containing said compound, and use thereof
07/02/2008EP1937677A1 Cb-1 modulating compounds and their use
06/2008
06/12/2008US20080139811 Reacting an amino, hydroxy substituted amide with a heterocyclic substituted carboxylic acid to produce (2S,3S,5S)-2-(2,6-Dimethylphenoxyacetyl) amino-3-hydroxy-5-[2S-1-imidazolidin-2-onyl)-3-methyl-butanoyl] amino-1,6-diphenylhexane; inhibitors of HIV infection
06/11/2008EP1928850A2 Agents for preventing and treating disorders involving modulation of the ryr receptors
06/11/2008EP1928849A1 New crystallization process of quetiapine hemifumarate
06/11/2008CN101198599A Process for preparing quetiapine fumarate
06/10/2008CA2369070C 1,4-benzothiazepine-1,1-dioxide derivatives substituted by sugar radicals, methods for the production thereof, medicaments containing these compounds and the use thereof
06/05/2008US20080132483 Administering (3R,5S)-N-propanesulfonyl-7-chloro-5-(2,3-dimethoxyphenyl)-1-(3-hydroxy-2,2-dimethylpropyl)-1,2,3,5-tetrahydro-4,1-benzoxazepine-3-acetamide; cerebral infarction
06/05/2008US20080132482 3-(2(R)-Cyclopentylmethyl-3 (S)-hydroxyl-1-oxo-5-phenylpentyl)amino-1-methyl-5-(4-fluoro-phenyl)-2,3-dihydro-1H-1,4-benzodiazepin-2-one; neurological disorders related to beta -amyloid production, Alzheimer's disease, Down's Syndrome
06/05/2008DE60129697T2 Kondensierte azepinderivate und ihre verwendung als antidiuretisches mittel Condensed azepine derivatives and their use as antidiuretic agent
06/04/2008CN101190902A Method for preparing pharmaceutical pure quetiapine fumarate
06/03/2008US7381743 Macrocycles for the treatment of cancer
05/2008
05/20/2008CA2231971C Hypolipidemic 1,4-benzothiazepine-1,1-dioxides
05/13/2008US7371853 Ring structuresC6.C6.C14N2O, C6.C6.C15N2O, C6.C6.C16N2O and C6.C6.C17N2O
05/08/2008US20080108597 New Use of Quetiapine
05/08/2008US20080108596 Antiserotonine agents; psycholgical disorders; headaches; kits
04/2008
04/23/2008EP1912960A1 1,4-benzothiazepine 1,1-dioxide derivative, process for its preparation, medicaments comprising this compound and use thereof as a hypolipidaemic
04/23/2008EP1565448A4 METHOD OF PREPARING 10H-DIBENZO b,f 1,4 THIAZEPIN-11-ONE
04/09/2008EP1907370A2 Novel 1,4-benzothiazepine-1,1-dioxide derivative having improved properties, method for the production thereof, medicaments containing said compound, and use thereof
04/08/2008US7355042 Sleep disorders; side effect reduction
04/08/2008US7354914 1-[3-Methyl-1-(5-methyl-6-oxo-benzo[b]-1,4-oxazepin-7-ylcarbamoyl)-butyl]-cyclohexanecarboxylic acid amide; inhibit processing of amyloid precursor protein (production of A beta -peptide); neurological disorders related to beta -amyloid production: Alzheimer's disease, Down's Syndrome
04/01/2008US7351824 Intermediates for oxazolidinone antibacterials; N-[3-Chloro-2-(R)-hydroxypropyl]-3-fluoro-4-morpholinyl aniline
04/01/2008CA2298974C Thiazolobenzoheterocycles, preparation and medicines containing same
03/2008
03/27/2008US20080076752 substituted structure of 3-amino-2-(2,5-difluorophenyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one; 6-amino-7-phenyl-1,4-thiazepan-5-one; -amino-2-phenyl-2,3-dihydro-1,5-benzoxazepin-4(5H)-one for treating neurological disorders such as Alzheimer's; inhibit the production of amyloid beta protein
03/26/2008EP1901752A2 Compositions and methods for viral inhibition
03/20/2008US20080070885 disorders related to beta-amyloid such as Alzheimer's disease, Down's Syndrome, memory and cognitive impairment, dementia, amyloidosis; (2R,4S) N-Butyl-4-hydroxy-2-methyl-4-((10S,13S)-10-methyl-8,11-dioxo-2-oxa-9,12-diaza-bicyclo[13.3.1]nonadeca-1(18),15(19),16-trien-13-yl)-butyramide for example
03/19/2008CN101146785A Novel anti-arrythmic and heart failure drugs that target the leak in the ryanodine receptor (RYR2)
03/13/2008WO2008028958A1 Cyclic sulfones useful as mitochondrial sodium-calcium exchangers
03/13/2008CA2661975A1 Benzothiazepines as antagonists for the mitochondrial sodium-calcium exchanger
03/12/2008CN101142197A N-hydroxyamides omega-substituted with tricyclic groups as histone deacetylase inhibitors, their preparation and use in pharmaceutical formulations
03/12/2008CN101142196A Ligands for G-protein coupled receptors
03/04/2008US7338948 Use of quetiapine
02/2008
02/13/2008CN101124209A Controlled release compositions comprising an antipsychotic agent
02/07/2008WO2007102074A3 Salts of quetiapine
01/2008
01/31/2008WO2008012524A1 Substituted aniline derivatives
01/31/2008US20080027038 N-Acylated lipophilic amino acid derivatives
01/31/2008CA2658913A1 Substituted aniline derivatives
01/24/2008US20080021005 Pegylated Ion Channel Modulating Compounds
01/23/2008EP1879874A2 Process for preparing quetiapine and quetiapine fumarate
01/10/2008WO2008003270A1 METHODS FOR THE PREPARATION OF SALTS OF 2-[2-(4-DIBENZO[B,F][l,4]THIAZEPIN-11-YL-1-PIPERAZINYL)ETHOXYL]ETHANOL (QUETIAPINE) AND FOR THE PURIFICATION THEREOF
01/10/2008WO2007102352A3 Process for preparing dibenzothiazepine compounds
01/10/2008WO2007050425A3 Lxr modulators
01/01/2008US7314930 Reducing 2-nitro-2'-carboxy-diphenylsulfide derivative in presence of hydrogen gas and reduction catalyst; subjecting 2-amino-2'-carboxy-diphenylsulfide derivative to dehydration-condensation to produce dibenzo[b,f][1,4]thiazepin-11-one compound
12/2007
12/27/2007US20070299050 TNF alpha inhibitors; inflammatory diseases such as rheumatoid arthritis, Crohn's disease, septic shock syndrome and atherosclerosis
12/26/2007EP1869007A1 Process for preparing quetiapine fumarate
12/26/2007CN100356916C Pharmaceutical compositions
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