| Patents for C07D 243 - Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms (5,961) |
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| 05/01/2008 | US20080103133 4-OXO-2,3,4,5-TETRAHYDRO-BENZO[b][1,4]DIAZEPINE DERIVATIVES |
| 05/01/2008 | US20080103128 Lactams substituted by cyclic succinates as inhibitors of abetta protein production |
| 04/30/2008 | CN100384825C Benzheterocyclic derivatives |
| 04/29/2008 | US7365076 for the prevention and treatment of conditions ameliorated by monoamine reuptake including, inter alia, vasomotor symptoms (VMS), sexual dysfunction, gastrointestinal and genitourinary disorders, chronic fatigue syndrome, fibromylagia syndrome, nervous system disorders |
| 04/29/2008 | US7365071 Heterocyclic compounds, preparation process and intermediates, and use as medicaments, in particular as β-lactamase inhibitors and antibacterials |
| 04/24/2008 | US20080096936 Sulfur substituted sulfonylaminocarboxylic acid N-arylamides, their preparation, their use and pharmaceutical preparations comprising them |
| 04/24/2008 | US20080096873 New compounds |
| 04/24/2008 | US20080096869 Adamantyl acetamides as 11-beta hydroxysteroid dehydrogenase inhibitors |
| 04/24/2008 | US20080096862 Lactam compounds and pharmaceutical use thereof |
| 04/23/2008 | EP1912679A2 Amine-containing lipids and uses thereof |
| 04/23/2008 | EP1689493A4 Calcitonin gene related peptide receptor antagonists |
| 04/23/2008 | CN100383129C Beta-amino heterocyclic dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes |
| 04/22/2008 | US7361687 Antagonists of the B2 receptor of bradykinin; analgesics; hyperalgesia and major algesia; cancer; nontoxic; industrial scale; 5-[[(2,4-dichloro-3-methylphenyl)sulphonyl]methylamino]-N-[[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]methyl]-N-methyl-pentanamide |
| 04/22/2008 | US7361666 Ligands for cellular receptors, including opiate receptors; side effect reduction; base structure is a saturated nitrogen-containing ring substituted with a tertiary amide that is N-substituted with an arylalkyl group |
| 04/22/2008 | US7361648 1-(4-{ethyl-[2-(4-methanesulfonylphenyl)-1-methylethyl]amino}butyl)-4-methanesulfonyl-[1,4]diazepan-2-one; repiratory system disorders: asthma and chronic obstructive pulmonary disease; nervous system, muscular,urogenital, gastrointestinal disorders; antiallergens; side effect reduction |
| 04/17/2008 | US20080090813 4-(3-hydroxy-1-propyl)-6-(3-trifluoromethylphenyl)-pyrimidine-2-carbonitrile; cysteine proteases (cathepsin K and S) inhibitor; antiinflammatory and analgesic agent; rheumatoid arthritis, multiple sclerosis, chronic and neuropathic pain |
| 04/17/2008 | US20080090803 Fatty alcohol drug conjugates |
| 04/16/2008 | EP1910315A2 Benzodiazepine derivatives, their preparation and the therapeutic use thereof |
| 04/16/2008 | CN101163685A Pharmaceutically active diazepanes |
| 04/16/2008 | CN101161678A Method for preparing diazepam artificial antigen |
| 04/15/2008 | US7358242 N-benzyl-2-[4-(1H-indol-3-ylmethyl)-5-oxo-1-phenyl-4,5-dihydro-2,3,6,10b-tetraaza-benzo[e]azulen-6-yl]-N-isopropyl-acetamide; cholecystokinin-A (CCK-A) receptor agonist; antidiabetic; obesity |
| 04/15/2008 | US7358239 Treating impaired fundic relaxation; [1(R),[A-(3 alpha ,4 alpha )]]-1-[1-[(3,4-dihydro-2H-1-benzopyran-2-yl)methyl]-3-methoxy-4-piperidinyl]-2(1H)-pyrimidinone |
| 04/10/2008 | WO2007144652A3 Parp inhibitors |
| 04/10/2008 | US20080085891 Asthma and allergic inflammation modulators |
| 04/09/2008 | CN101160290A 7-membered ring compound, process for producing the same, and medicinal use thereof |
| 04/09/2008 | CN100379735C 1,2,3,4,7,8-hexahydro-6h-[1,4]diazepino[6,7,1-1j]quinoline derivatives as antipsychotic and antiobesity agents |
| 04/08/2008 | US7355042 Sleep disorders; side effect reduction |
| 04/08/2008 | US7354914 1-[3-Methyl-1-(5-methyl-6-oxo-benzo[b]-1,4-oxazepin-7-ylcarbamoyl)-butyl]-cyclohexanecarboxylic acid amide; inhibit processing of amyloid precursor protein (production of A beta -peptide); neurological disorders related to beta -amyloid production: Alzheimer's disease, Down's Syndrome |
| 04/03/2008 | WO2008038600A1 1,4-benzodiazepine derivative, pharmaceutical composition comprising the same, and use of the same for medical purposes |
| 04/02/2008 | EP1904460A1 Multidentate aza ligands able to complex metal ions and the use thereof in diagnostics and therapy |
| 04/02/2008 | CN100378096C Diazepanes derivatives useful as LFA inhibitors |
| 04/01/2008 | US7351839 Process for the preparation of 1,2,3,4,8,9,10, 10a-octahydro-7bH-cyclopenta[b][1,4]diazepino-[6,7,1-hi]indole derivatives |
| 04/01/2008 | US7351825 4-[5-((1S,2R)-1-Carboxy-2-phenyl-cyclopropylsulfamoyl)-thiophen-2-yl]-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester; aggrecanase and matrix metalloproteinase (with zinc in the catalytic active center) (MMP) inhibitor; antiarthritic agent: osteoarthritis, rheumatoid arthritis |
| 04/01/2008 | CA2298974C Thiazolobenzoheterocycles, preparation and medicines containing same |
| 03/27/2008 | WO2008034735A2 4-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]diazepine derivatives |
| 03/27/2008 | CA2663240A1 4-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]diazepine derivatives |
| 03/26/2008 | EP1556362B1 Beta-amino heterocyclic dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes |
| 03/26/2008 | CN100376575C [1,4]diazepino[6,7,1-ij]quinoline derivatives as anti psychotic and antiobesity agents |
| 03/26/2008 | CN100376569C Inhibitors of farnesyl protein transferase |
| 03/25/2008 | US7348347 Serotonin reuptake inhibitors; for depression and pain; 2-cyclohexyl-N-{4-[4-(2-dimethylaminoethyl)piperazin-1-carbonyl]-4,5,6,7-tetrahydrobenzthiazol-2-yl)-acetamide |
| 03/20/2008 | WO2007140154A3 Salts and crystal modifications thereof |
| 03/20/2008 | US20080070894 Anticancer agents; PLK1 inhibitors; PLK=polo-like kinase; imidazo(1,2-a)pyridines such as 5-bromo-4-[8-(difluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[(1S)-1-phenylethyl]-2-pyrimidinamine |
| 03/20/2008 | CA2663161A1 Quinazolinone and isoquinolinone acetamide derivatives |
| 03/19/2008 | EP1490344B1 Anxiolytic agents with reduced sedative and ataxic side effects |
| 03/13/2008 | WO2007052167A3 Stable composition for a pharmaceutical formulation containing olanzapine |
| 03/13/2008 | US20080064684 Sub-type selective serotonin receptor agonists; antidepressants; schizophrenia, Alzheimer's Disease, Parkinson's Disease; alkylation or amidation of the heterocyclylbenzazole with an alkylhalide or acylhalide |
| 03/13/2008 | US20080064682 1,5-diaryl-3-N-heterocycylcarbonylpyrazoles; antiagglomerants that do not inhibit cyclooxygenases; antiischemic agents |
| 03/12/2008 | EP1656355B1 Piperazine derivatives and methods of use |
| 03/12/2008 | CN101142197A N-hydroxyamides omega-substituted with tricyclic groups as histone deacetylase inhibitors, their preparation and use in pharmaceutical formulations |
| 03/12/2008 | CN101142196A Ligands for G-protein coupled receptors |
| 03/11/2008 | US7342008 Containing a benzodiazepine ring; 2-Cyclopentylmethyl-3(S)-hydroxyl-1-oxo-5-phenylpentyl)amino-1-methyl-5-(4-fluoro-phenyl)-2,3-dihydro-1H-1,5-benzodiazepin-2-one; Alzheimer's disease and Down's Syndrome; prevent the formation of neurological deposits of amyloid protein |
| 03/11/2008 | US7342007 prevent the formation of neurological deposits of amyloid protein; Alzheimer's disease, cognitive impairment; novel lactarns; N2-[(3,5-difluorophenyl)acetyl]-N1-[(3S,7S)-1-methyl-2-oxo-7-phenyl-2,3,4,7-tetrahydro-1H-azepin-3-yl]-L-alaninamide; secretase inhibitors |
| 03/05/2008 | EP1893218A2 Unsolvated benzodiazepine compositions and methods |
| 03/05/2008 | CN101134755A Quinazoline(di) ones for invertebrate pest control |
| 02/28/2008 | WO2008023847A1 P2x4 receptor antagonist |
| 02/28/2008 | US20080051388 Novel Compounds That Inhibit Factor Xa Activity |
| 02/26/2008 | US7335774 Quinolinone derivatives |
| 02/21/2008 | US20080045509 Substituted benzyl amine compounds |
| 02/21/2008 | US20080045508 Substituted aminomethyl benzamide compounds |
| 02/21/2008 | US20080045507 Substituted benzamide modulators of the histamine h3 receptor |
| 02/21/2008 | US20080045506 Pyrrolidine Derivatives as Histamine Receptors Ligands |
| 02/21/2008 | US20080045505 1-(isopropyl)-4-{[4-(tetrahydro-2H-pyran4-yloxy)phenyl]carbonyl}hexahydro-1H-1,4-diazepine, used in the treatment of nervous system and psychological disorders such as Alzheimer's disease or as cognition activators |
| 02/21/2008 | US20080045500 Nerve Regeneration Stimulator |
| 02/21/2008 | US20080045497 Substituted aniline derivatives |
| 02/20/2008 | EP1436271B1 Phenyl-piperazine derivatives as serotonin reuptake inhibitors |
| 02/20/2008 | EP1289968B1 Cyclic urea compounds and preparation thereof |
| 02/19/2008 | US7332524 Adamantyl acetamides as 11-beta hydroxysteroid dehydrogenase inhibitors |
| 02/19/2008 | US7332483 3-(5-benzamido-2-chlorophenyl)-7-methoxy-3,4-dihydroquinazolin-4-one;cytokines (tumor necrosis factor and interleukins) inhibitor; antiinflammatory agent, rheumatoid arthritis, osteoarthritis, psoriasis, chronic obstructive pulmonary disease |
| 02/14/2008 | WO2008018778A1 New heterocyclic compounds containing nitrogen atoms or pharmaceutically acceptable salts thereof, process for the preparation thereof and pharmaceutical composition comprising the same for treatment of cancer |
| 02/14/2008 | US20080039449 [1,4]benzodiazepine derivatives, used for treating osteoarthritis, pancreatitis, glomerulonephritis, rheumatoid arthritis, inflammatory bowel disease, Crohn's disease, psoriasis, graft vs host disease, leukemia, septic shock, multiple sclerosis, and inflammatory bowel disease |
| 02/14/2008 | US20080039447 CDK-Inhibitory pyrimidines, their production and use as pharmaceutical agents |
| 02/14/2008 | US20080039446 Substituted isoindoles and their use |
| 02/14/2008 | CA2661131A1 New heterocyclic compounds containing nitrogen atoms or pharmaceutically acceptable salts thereof, process for the preparation thereof and pharmaceutical composition comprising the same for treatment of cancer |
| 02/12/2008 | US7329653 (4-cyclohexyl-phenyl)-(4H, 10H-3a,5,9-triaza-benzo[f]azulen-9-yl)-methanone; antidiuretic, anticoagulant, diabetes insipidus, nocturnal enuresis, nocturia, urinary incontinence, delay of urination, or bleeding |
| 02/07/2008 | WO2007035722B1 Methods and compositions for stimulating neurogenesis and inhibiting neuronal degeneration |
| 02/07/2008 | WO2006136564A9 Multidentate aza ligands able to complex metal ions and the use thereof in diagnostics and therapy |
| 02/07/2008 | US20080032968 New compounds |
| 02/06/2008 | CN101119717A Substituted phenols as active agents inhibiting vegf production |
| 02/05/2008 | US7326789 E.g., 2-(4-Chloro-phenylsufonylamino)-4,5-dimethoxy-N-(4-(thiomorpholine-4-sulfonyl)-phenyl)-benzamide; cardiovascular disorders; hypotensive agents; angina pectoris, cardiac insufficiency, thrombolytic agents; atherosclerosis; activating soluble guanylate cyclase to adjust a disturbed cyclic GMP balance |
| 02/05/2008 | US7326701 Lactam compounds and pharmaceutical use thereof |
| 01/31/2008 | US20080027042 Novel Aminopyridine Derivatives Having Aurora a Selective Inhibitory Action |
| 01/31/2008 | US20080027038 N-Acylated lipophilic amino acid derivatives |
| 01/29/2008 | US7323458 Dihydrobenzodiazepins and their use for treating dyslipidemia |
| 01/29/2008 | US7323457 Containing a perhydro-4-benzodiazepinylphenyl group 1-substituted with a methylaminoacetyl-, 4-piperidinylcarbonyl- or 2-pyrrolidinylcarbonyl- group: 4-(Piperidin-4-yl)carbonyl-1-{[2-(2-benzofuranoyl)amino]-4-[1-aminocarbonyl-2-(2-naphthyl)ethylamino]carbonylaminophenyl}homopiperazine; osteoporosis |
| 01/24/2008 | WO2008009758A1 Compound that can inhibit ubc13-uev interactions, pharmaceutical compositions and therapeutic uses |
| 01/24/2008 | US20080021019 immunodeficiencies, cancers, cardiovascular diseases, endocrine disorders, Parkinson's disease, metabolic diseases, tumorigenesis, Alzheimer's disease, heart disease, diabetes, neurodegeneration, inflammation, kidney disease, atherosclerosis and airway disease; substituted pyrazine compounds |
| 01/24/2008 | US20080021018 (S)-(-)-1-(4-Fluoroisoquinolin-5-Yl)Sulfonyl-2-Methyl-1,4-Homopiperazine Hydrochloride Dihydrate |
| 01/24/2008 | US20080021014 CYCLIC MALONAMIDES AS INHIBITORS OF Abeta PROTEIN PRODUCTION |
| 01/24/2008 | CA2658327A1 Compound that can inhibit ubc13-uev interactions, pharmaceutical compositions and therapeutic uses |
| 01/23/2008 | EP1880208A2 Detection of ortho-diamine residues in analytes containing residual cyclizing agents background of the invention |
| 01/23/2008 | EP1879872A1 Seven-membered heterocyclic carbenes and their metal complexes |
| 01/23/2008 | EP1196404B1 Piperazine derivatives as modulators of chemokine receptor activity |
| 01/22/2008 | USRE40033 Process for preparing 2-methyl-thieno-benzodiazepine |
| 01/22/2008 | US7321001 carboxylic acid derivatives which modulate the function and/or expression of proteins involved in atopic diseases, inflammatory conditions and cancer |
| 01/17/2008 | US20080015184 Urea Substituted Imidazopyridines, Imidazoquinolines, and Imidazonaphthyridines |
| 01/16/2008 | EP1878728A2 Derivatives of piperazine and higher homologues thereof for the treatment of inflammation-related disorders |
| 01/16/2008 | EP1687288B1 Substituted aryl cycloalkanol derivatives and methods of their use |
| 01/16/2008 | CN101106998A Mitotic kinesin inhibitors |
| 01/15/2008 | US7319097 Treatment of type II diabetes with benzenesulfonamide substituted with an N-heterocycle: N-[2-amino-5-(1,4-diazepan-1-yl)phenyl]benzenesulfonamide, N-[4-amino-5-(piperazinyl)phenyl]benzenesulfonamide, 3-amino-4-(5-methyl-2,5-diaza-bicyclo[2.2.1]hept-2-yl)-N-phenyl-benzenesulfonamide hydrochloride |
| 01/10/2008 | WO2007135295A3 Derivatives of 2-alkoxy-3,4,5-trihydroxy-alkyl amides, preparation and use thereof, and compositions containing the same |