Patents
Patents for C07D 243 - Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms (5,961)
03/2007
03/06/2007US7186713 Farnesyl dibenzodiazepinones and methods of treating cancer using same
03/06/2007US7186400 Multidentate aza ligands able to complex metal ions and the use thereof in diagnostics and therapy
03/06/2007US7186277 hair dyes with improved colorfastness, washfastness, photostability, color uniformity and tinctorial strength
03/01/2007WO2007023273A1 Cell migration modulating compounds
03/01/2007WO2007022638A1 Benzodiazepine and benzopiperazine analog inhibitors of histone deacetylase
03/01/2007WO2006117672A3 Detection of ortho-diamine residues in analytes containing residual cyclizing agents
03/01/2007WO2005117876A8 Dual small molecule inhibitors of cancer and angiogenesis
03/01/2007US20070049580 Anxiolytic agents with reduced sedative and ataxic effects
03/01/2007CA2620414A1 Benzodiazepine and benzopiperazine analog inhibitors of histone deacetylase
02/2007
02/28/2007EP1756070A2 Crystalline forms of n-desmethylclozapine
02/28/2007CN1922162A Derivatives of alkylpiperazine- and alkylhomopiperazine-carboxylates, preparation method thereof and use of same as FAAH enzyme inhibitors
02/22/2007US20070043033 Unsolvated benzodiazepine compositions and methods
02/22/2007US20070043029 11-Phenyl-dibenzodiazepine derivatives as rxr-antagonists
02/21/2007EP1754707A2 Multicyclic compounds and their use as inhibitors of PARP, VEGFR2 and MLK3 enzymes
02/21/2007EP1753766A1 Tetraazabenzo(e)azulene derivatives and analogs thereof
02/21/2007CN1917921A Calcitonin gene related peptide receptor antagonists
02/21/2007CN1915964A Adamantyl acetamides as 11-beta hydroxysteroid dehydrogenase inhibitors
02/20/2007US7179839 For therapy of cardiovascular diseases, stable or unstable angina pectoris, coronary heart disease, stable or unstable angina pectoris, coronary heart disease, Prinzmetal angina, acute coronary syndrome, heart failure, myocardial infarction
02/20/2007CA2119745C Nonpeptidyl integrin inhibitors having specificity for gpiibiiia receptor
02/15/2007US20070036854 Therapeutic applications of pro-apoptotic benzodiazepines
02/14/2007EP1751119A1 Novel fused heterocycles and uses thereof
02/14/2007EP1750706A1 Dual small molecule inhibitors of cancer and angiogenesis
02/14/2007EP1296961B1 1,4-diazepan-2,5-dione derivatives and their use as nk-1 receptor antagonists
02/14/2007CN1911915A Lactam compound and medicinal use thereof
02/14/2007CN1300110C Hydroxamate derives useful as deacetylase inhibitors
02/13/2007US7176306 Hydroxyalkyl cyclic diamine compound
02/13/2007US7176242 N,N′-substituted-1,3-diamino-2-hydroxypropane derivatives
02/13/2007US7176195 Treatment of nocturnal enuresis, nocturia, polyuria resulting from central diabetes insipidus, urinary incontinence or bleeding disorders such a hemophilia
02/13/2007CA2285037C Novel 2-(iminomethyl)amino-phenyl derivatives, preparation, application as medicines and pharmaceutical compositions containing same
02/08/2007WO2006071775A3 Novel compounds useful for bradykinin b1 receptor antagonism
02/07/2007EP1749824A1 Benzodiazepine derivatives, their preparation and the therapeutic use thereof
02/07/2007EP1749818A2 Phenyl-piperazine derivatives as serotonin reuptake inhibitors
02/07/2007CN1910137A Aryl aniline derivatives as beta2 adrenergic receptor agonists
02/07/2007CN1298715C Non-imidazole compounds as histamine H3 antagonists
02/06/2007US7173039 Compounds that modulate or inhibit enzymes for occular diseases
02/06/2007US7173035 Arylsulfonamide compounds
02/01/2007US20070027143 Novel substituted 2,3-benzodiazepine derivatives
02/01/2007US20070027141 Derivatives of alkylpiperazine and alkylhomopiperazine-carboxylates, preparation method thereof and use of same as fatty acid amido hydrolase enzyme inhibitors
02/01/2007US20070027132 Containing a benzodiazepine ring; 2-Cyclopentylmethyl-3(S)-hydroxyl-1-oxo-5-phenylpentyl)amino-1-methyl-5-(4-fluoro-phenyl)-2,3-dihydro-1H-1,5-benzodiazepin-2-one; Alzheimer's disease and Down's Syndrome; prevent the formation of neurological deposits of amyloid protein
01/2007
01/30/2007US7169796 Polyarylcarboxamides useful as lipid lowering agents
01/25/2007WO2006089298A3 Pyrimidine-fused diazepine derivatives and indole-fused pteridines
01/24/2007CN1901971A Cyclopropane compounds and pharmaceutical use thereof
01/23/2007US7166587 Gamma -secretase inhibitors; for treatment of Alzheimer's disease; e.g 2,3-difluoro-benzyl)-carbamic acid (S)-1-(5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-ylcarbamoyl)-ethyl ester
01/18/2007WO2006102176A3 Process for preparing crystalline form i of olanzapine
01/17/2007EP1742707A2 Treatment of cns disorders using cns target modulators
01/17/2007EP1537117B1 Benzotriazabicyclic derivatives and use thereof as beta-lactamase inhibitors and anti-bacterial agents
01/17/2007EP1341793B1 Crf receptor antagonists and methods relating thereto
01/17/2007CN1898217A Benzo'1,4-diazepin-2-one derivatives as phosphodiesterase pde2 inhibitors, preparation and therapeutic use thereof
01/11/2007WO2006020959A3 Substituted benzofused heterocycles
01/11/2007US20070010489 Saquinavir-like, a Lopinavir-like, a Ritonavir-like, a Indinavir-lik, a atazanavir-like, Nelfinavir-like.a Tipranavir-like, a Amprenavir-like, a KNI-like. a cyclic carbonyl-like phosphonate HIV protease inhibitors; drug designing
01/10/2007EP1740577A2 Selected cgrp antagonists, methods for the production thereof, and use thereof as medicaments
01/10/2007EP1740185A1 Benzodiazepines for treating or preventing rsv infection
01/10/2007CN1894217A Substituted dibenzo-azepine and benzo-diazepine derivatives useful as gamma-secretase inhibitors
01/10/2007CN1294134C Cyclohexylphenyl vasopression agonists
01/09/2007US7160880 Producing sedation, hypnosis, inducing anxiolysis, muscle relaxation; treating convulsions; CNS depressants; pharmacodynamic
01/09/2007US7160879 Melanin concentrating hormone receptor ligands: substituted 2-(4-benzyl-piperazin-1-ylmethyl)- and 2-(4-benzyl-diazepan-1-ylmethyl)-1H-benzoimidazole analogues
01/09/2007US7160878 Substituted heterocyclic amides
01/09/2007US7160875 Malonamide derivatives
01/09/2007US7160872 Methods to treat conditions mediated by chemokine receptors
01/09/2007CA2266444C Olanzapine dihydrate d
12/2006
12/28/2006WO2006136564A1 Multidentate aza ligands able to complex metal ions and the use thereof in diagnostics and therapy
12/27/2006EP1597260B1 Triazole compounds useful in therapy
12/27/2006CN1886407A Bicyclic pyrazolyl and imidazolyl compounds and uses thereof
12/26/2006US7153850 Lactam compounds and pharmaceutical use thereof
12/26/2006US7153849 5HT1A antagonist; obsessive-compulsive disorder, panic attacks, generalized anxiety disorder, and social anxiety disorder
12/21/2006WO2006104997A3 Tartaric acid salts of a dipeptidyl peptidase-iv inhibitor
12/21/2006WO2006012130A3 Polyproplene grids manufactured with a beta nucleation additive, the method of manufacture and uses thereof
12/21/2006US20060287294 Aspartyl protease inhibitors
12/21/2006US20060287293 1-(4-{ethyl-[2-(4-methanesulfonylphenyl)-1-methylethyl]amino}butyl)-4-methanesulfonyl-[1,4]diazepan-2-one; repiratory system disorders: asthma and chronic obstructive pulmonary disease; nervous system, muscular,urogenital, gastrointestinal disorders; antiallergens; side effect reduction
12/20/2006EP1733758A1 Methods for administration of a farnesyl dibenzodiazepinone
12/20/2006CN1882551A Hexahydrodiazepinones as dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes
12/20/2006CN1290500C Retroviral protease inhibitor combinations
12/19/2006US7151098 Glutamate receptor antagonists
12/14/2006US20060281734 3-[5-(3-acetamidobenzamido)-2-methylphenyl]-6-(4-methylpiperazin-1-yl)-3,4-dihydroquinazolin-4-one for example; treating rheumatoid arthritis, osteoarthritis, psoriasis, chronic obstructive pulmonary disease; inhibitor of cytokine-mediated disease
12/13/2006EP1730117A2 Thiourea compositions and uses thereof
12/12/2006US7148238 E.g., 4-[2-(4-Methylphenoxy)- or 4-[2-(4-Methylphenylsulfanyl)-phenyl]piperidine or the hydrochloride or oxalate; treating depression, anxiety disorder, and obsessive compulsive disorder.
12/12/2006CA2245926C 7-phenyl-1,4-diazepane compounds, process for their preparation, and pharmaceutical compositions containing them
12/07/2006US20060276456 Such as [1,1-biphenyl]-4-yl-(5,11-dihydro-10H-dibenzo[b,e][1,4]diazepin-10-yl)methanone; for treatment of diabetes insipidus, nocturnal enuresis, nocturia, urinary incontinence, or hemophilia
12/06/2006CN1875005A Malonamide derivatives blocking the activtiy of gamma-secretase
12/06/2006CN1872854A Antibiotic in lactam class, and prepartion method
12/05/2006US7144884 E.g., 4-[2-(4-Methylphenoxy)- or 4-[2-(4-Methylphenylsulfanyl)-phenyl]-3,6-dihydro-2H-pyridine or piperazine or the hydrochloride or oxalate; treating depression, anxiety disorder, and obsessive compulsive disorder.
12/05/2006US7144883 Substituted fused ring sulfonamides containing, e.g., naphthalene, isoquinoline, quinoline, benzofuran or benzothiophene rings; treatment of conditions relating to obesity, type II diabetes and CNS disorders
12/05/2006US7144880 Compositions relating to novel compounds and targets thereof
11/2006
11/29/2006EP1726952A1 Method of in vivo screening of therapeutic agent for memory/learning dysfunction by schizophrenia
11/29/2006EP1725236A1 Novel m3 muscarinic acetylcholine receptor antagonists
11/29/2006CN1871223A 8-chloro-2,3-benzodiazepine derivatives
11/28/2006US7141563 Used for prophylaxis and therapy of central nervous system disorders, including obsessive-compulsive disorder, depression, anxiety, generalized anxiety disorder, schizophrenia, panic disorder, migraine, sleep disorders
11/28/2006US7141561 Substituted diaryl heterocycles, process for their preparation and their use as medicaments
11/23/2006WO2006084870A3 Alkyl substituted homopiperazine derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
11/23/2006US20060264420 Tteating cell proliferation disease by modulation of kinesin and treatment of cancer
11/23/2006US20060264417 N-(3-tetrahydrobenzodiazepinonyl)succamides: 2R,3S)N1-[1,3,4,5-tetrahydro-1-(3-phenoxybenzyl)-2-oxo-5-(phenyl)-2H-1,5-benzodiazepin-3-yl]-2-(2-methylpropyl)-3-(propyl)-butanediamide; inhibit production of A beta -peptide, preventing neurological amyloid deposits; Alzheimer's disease
11/22/2006EP1723955A1 Medicine for prevention and/or treatment of ischemic circulatory disease
11/22/2006EP1351933B1 Il-8 receptor antagonists
11/21/2006US7138407 Phenyl-piperazine derivatives as serotonin reuptake inhibitors
11/21/2006CA2511750C Dibenzodiazepinone analogues, processes for their production and their use as pharmaceuticals
11/21/2006CA2247257C Novel aryl glycinamide derivatives, method of producing said derivatives and pharmaceutical compositions containing these compounds
11/16/2006WO2006088541A3 Quinoline derivatives and uses thereof
11/16/2006US20060258638 Succinoylamino lactams as inhibitors of A-beta protein production
11/15/2006EP1720848A1 Derivatives of alkylpiperazine- and alkylhomopiperazine- carboxylates, preparation method thereof and use of same as faah enzyme inhibitors
11/15/2006CN1863797A Cyclic amine BACE-1 inhibitors having a benzamide substituent
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