| Patents for C07D 225 - Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom (1,649) |
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| 03/08/2005 | US6864250 N-acylated lipophilic amino acid derivatives |
| 03/03/2005 | WO2005019181A1 Migrastatin analog cell migration inhibitors |
| 03/03/2005 | WO2005018545A2 Macrocyclic beta-secretase inhibitors for the treatment of alzheimer's disease |
| 03/03/2005 | CA2535337A1 Macrocyclic beta-secretase inhibitors for the treatment of alzheimer's disease |
| 02/17/2005 | WO2004080391A3 Novel antibacterial agents |
| 02/15/2005 | US6855705 Non-polyene and ansa macrolide antibiotics such as 11-O-methyl -17-(1-azetidinyl)-17-demethoxygeldanamycin, used as antiproliferative or anticarcinogenic agents |
| 02/10/2005 | WO2003050295A3 Assays and implements for determining and modulating hsp90 binding activity |
| 02/08/2005 | US6852713 Lactam derivatives and methods of their use |
| 02/02/2005 | EP1297175A4 Methods and compounds for modulating nuclear receptor coactivator binding |
| 02/02/2005 | CN1187342C Substituted 1-aminoalkyl-lactams compound and their use as muscarinic receptor antagonists |
| 02/01/2005 | US6849597 Administering a growth hormone secretagogue to a mammal, for preventing nerve cells degeneration or death of neurons |
| 01/27/2005 | WO2005007618A1 Method for production of $g(a),$g(b)-unsaturated amide compounds |
| 01/27/2005 | CA2531603A1 Method for production of .alpha., .beta.-unsaturated amide compounds |
| 01/12/2005 | EP1165532B1 Antibacterial agents |
| 01/12/2005 | CN1562975A Method for preparing 1-methyl-3-ethyl-3-(3-hydroxy phenyl)-hexa hydrogen-1 H azepin hydrochloride |
| 01/05/2005 | EP1493738A1 Epothilone derivatives |
| 12/29/2004 | EP1435939A4 Process for preparing 17-allyl amino geldanamycin (17-aag) and other ansamycins |
| 12/29/2004 | CN1558757A Process for preparing 17-allyl amino geldanamycin (17-AAG) and other ansamycins |
| 12/23/2004 | US20040259876 Bicyclic compound, production and use thereof |
| 12/22/2004 | EP1489106A1 Arene-ruthenium complexes immobilized on polymers, catalysts consisting of the complexes, and processes for organic syntheses with the same |
| 12/08/2004 | EP1484322A1 Process for producing optically active sulfoxide derivative |
| 12/08/2004 | EP1483395A1 Process to prepare and isolate geldanamycin |
| 12/08/2004 | CN1178922C Substituted 1-aminoalkyl-lactams compound and their use as muscarinic receptor antagonists |
| 12/02/2004 | US20040242553 Drugs to improve synaptic transmission |
| 11/18/2004 | WO2004034970A3 Macrocyclic lactams |
| 11/16/2004 | US6818645 2-amino-trihydroindole or tetrahydronapthalene-2-yl derivatives, useful for disease state associated with smooth muscle disorders, such as gastrointestinal and urogenital disorders |
| 11/11/2004 | US20040224936 Macrocyclic compounds useful as pharmaceuticals |
| 11/04/2004 | WO2004093796A2 Lactam derivatives and methods of their use |
| 11/04/2004 | WO2004087673A3 Migrastatin analogs and uses thereof |
| 11/03/2004 | EP1472230A2 Ansamycins having improved pharmacological and biological properties |
| 11/03/2004 | CN1543452A 1,4-disubstituted benzenes as insecticides |
| 10/28/2004 | WO2004082357A3 Novel method for the synthesis of derivatives of (2s, 3as, 7as)-1-[(s)-alanyl]-octahydro-1h-indole-2-carboxylic acid and application thereof to the synthesis of perindopril |
| 10/21/2004 | US20040209857 Pharmaceutical compositions containing the compounds and methods for their use are also disclosed. Binding opioid receptors to treat a condition or disease selected from the group consisting of: gastrointestinal dysfunction, ileus, |
| 10/20/2004 | EP1468990A1 Piperazine derivative |
| 10/20/2004 | EP1289964B1 Substituted 1-aminoalkyl-lactams and their use as muscarinic receptor antagonists |
| 10/14/2004 | WO2004087673A2 Migrastatin analogs and uses thereof |
| 10/14/2004 | WO2004087672A1 Migrastatin analog compositions and uses thereof |
| 10/14/2004 | US20040204395 Water-soluble drugs and methods for their production |
| 10/14/2004 | CA2520377A1 Migrastatin analog compositions and uses thereof |
| 10/07/2004 | WO2004084809A2 Neuroprotective macrocylic compounds and methods for their use |
| 09/30/2004 | WO2004083237A1 Novel method for the synthesis of (2s, 3as, 7as)-perhydroindole-2-carboxylic acid and the esters thereof and application to the synthesis of perindopril |
| 09/30/2004 | WO2004082357A2 Novel method for the synthesis of derivatives of (2s, 3as, 7as)-1-[(s)-alanyl]-octahydro-1h-indole-2-carboxylic acid and application thereof to the synthesis of perindopril |
| 09/23/2004 | WO2004080391A2 Novel antibacterial agents |
| 09/23/2004 | CA2801100A1 Novel antibacterial agents |
| 09/15/2004 | EP1322325A4 Inhibiting hepatitis c virus processing and replication |
| 08/11/2004 | CN1519233A 12-(imino ether)-1, 15-pentadelactam, as well as preparation method and its application in bactericide |
| 08/04/2004 | CN1518447A Synthesis and evaluation of novel phthalimide mimics as anti-angiogenic agents |
| 08/03/2004 | US6770668 Pharmaceutically active compounds and methods of use |
| 07/28/2004 | CN1515563A Aryl substituted piperazine for curing benign prostatauxe |
| 07/28/2004 | CN1515556A Intermediate compound for preparing aryl substituted piperazine |
| 07/20/2004 | US6765023 Use of substituted N, N-disubstituted reverse aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity |
| 07/14/2004 | EP1435939A2 Process for preparing 17-allyl amino geldanamycin (17-aag) and other ansamycins |
| 07/14/2004 | EP0983248B1 Analogs of duocarmycin and cc-1065 |
| 07/14/2004 | CN1157189C Semi-synthetic ecteinascidins |
| 07/08/2004 | US20040132997 Macrocyclic lactams |
| 07/01/2004 | WO2004054624A1 Cytotoxins and diagnostic imaging agents comprising hsp90 ligands |
| 07/01/2004 | CA2549463A1 Cytotoxins and diagnostic imaging agents comprising hsp90 ligands |
| 06/30/2004 | EP0945436B1 Cytotrienins, process for preparing the same, and antitumor agent |
| 06/29/2004 | US6756500 Subjecting substituted alpha, omega-diene in presence of ruthenium, osmium or molybdenum homogeneous or heterogeneous catalyst to metathesis reaction in presence of ionic liquid to form cyclic compound |
| 06/24/2004 | US20040122030 Substituted phthalimide and isoquinoline derivatives; thalidomide analogs that lack the piperidine-2,6-dione moiety of thalidomide |
| 06/23/2004 | EP1429783A2 Multi-use multimodal imaging chelates |
| 06/22/2004 | US6753429 1,4-disubstituted benzenes as insecticides |
| 06/17/2004 | WO2004050623A1 Methods for preparing phenylalkyne derivatives |
| 06/17/2004 | CA2507875A1 Methods for preparing phenylalkyne derivatives |
| 06/10/2004 | WO2003066005A3 Ansamycins having improved pharmacological and biological properties |
| 06/08/2004 | US6747055 Water-soluble drugs and methods for their production |
| 06/03/2004 | US20040106788 asymmetric hydrogenation of a lactam-enamide; multi-step synthesis |
| 06/03/2004 | US20040106593 Highly enantiomerically pure lactam-substituted propanoic acid derivatives and methods of making and using same |
| 06/02/2004 | EP1423376A1 Bicyclic compound, production and use thereof |
| 05/26/2004 | EP1420747A2 Benzoquinone ansamycins |
| 05/12/2004 | CN1149081C Arylsubstituted piperazines useful in the threatement of bening prostatic hyperlasia |
| 05/06/2004 | US20040087581 Heterocyclylalkylamines as muscarinic receptor antagonists |
| 04/29/2004 | WO2004034970A2 Macrocyclic lactams |
| 04/22/2004 | US20040077058 Domains of geldanamycin and herbimycin polyketide synthases, polynucleotides that encode such enzymes, and to host cells in which such encoding polynucleotides can be advantageously expressed |
| 04/20/2004 | US6723753 Substituted n-benzyl-n-phenyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity |
| 03/25/2004 | US20040059109 Alanine 2, 6-dialkoxyphenyl ester derivatives as hypnotics |
| 03/24/2004 | CN1484639A Geldanamycin derivative and method of treating cancer same |
| 03/23/2004 | US6710089 Substituted N-fused-phenyl-N-benzyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity |
| 03/23/2004 | US6710073 Drugs that induce long term potentiation (ltp) and enhance cognitive function in mammals |
| 03/18/2004 | WO2003106653A3 Recombinant polynucleotides encoding pro-geldanamycin producing polyketide synthases and accessory proteins, and uses thereof |
| 03/18/2004 | US20040053909 Administering to a cancer patient a geldanamycin derivative containing dimethylaminoethylamine (at 17the position) group attached to the ring, for the treatment of cancer |
| 03/16/2004 | CA2096460C Dual action inhibitors |
| 03/04/2004 | WO2003013430A3 Benzoquinone ansamycins |
| 03/02/2004 | US6699988 By reacting phosgene and lactam in the presence of a non-nucleophilic aliphatic tertiary amine, such as n,n-diisopropylethylamine; high purity, good yields |
| 03/02/2004 | US6699898 Method of treating coronary artery disease or other cetp-mediated disorders in a subject by administering a therapeutically effective amount of a compound of one of claims |
| 02/25/2004 | EP1073629B1 Anion-complexing compound, method of preparing the same, an ion-selective membrane and a sensor provided with such a compound or membrane |
| 02/24/2004 | US6696472 Substituted N-phenoxy-N-phenyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity |
| 02/24/2004 | US6696435 For treating atherosclerosis, other coronary artery diseases; 3-((3-(3-trifluoromethoxyphenoxy)phenyl)((3-(1,1,2,2-tetrafluoroethoxy) -phenyl)methyl) amino)-1,1,1-trifluoro-2-propanol for example |
| 02/19/2004 | US20040034018 2-amino-trihydroindole or tetrahydronapthalene-2-yl derivatives, useful for disease state associated with smooth muscle disorders, such as gastrointestinal and urogenital disorders |
| 02/18/2004 | EP1389103A2 Synthesis and evaluation of novel phthalimide mimics as anti-angiogenic agents |
| 02/03/2004 | US6686477 Multistep chemical synthesis, including asymmetric hydrogenation of a lactam-enamide to produce an intermediate that can be used to make unspecified pharmaceuticals |
| 01/27/2004 | US6683099 Substituted N,N-disubstituted cycloalkyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity |
| 01/20/2004 | US6680314 Azacyclooctane and heptane derivatives, their preparation and use in therapy |
| 01/13/2004 | US6677382 Halogenated oxyamines, used as enzyme inhibitors for prophylaxis of atherosclerosis and cardiovascular disorders, and as antilipemic agents |
| 01/13/2004 | US6677380 Antilipemic agents such as 3(3-(4-chloro-3-ethyl-phenoxy)-phenyl)((3-(1,1,2,2 -tetrafluoroethoxy)phenyl)methyl))amino)-1,1,1-trifluro-2-propanthiol, used for prophlaxis of cardiovascular disorders and atherosclerosis |
| 01/13/2004 | US6677379 Such as 3-((3-(3-trifluoromethoxyphenoxy)phenyl)((3-(1,1,2,2-tetrafluoroethoxy) -phenyl)methyl) amino)-1,1,1-trifluoro-2-propanol for treatment of coronary artery disease |
| 01/13/2004 | US6677375 Substituted N,N-bis-benzyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity |
| 01/13/2004 | US6677353 Substituted N-phenyl-N-heteroaralkyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity |
| 01/02/2004 | EP1373215A1 Geldanamycin derivative and method of treating cancer using same |
| 01/02/2004 | EP1373188A1 Alanine 2,6-dialkoxyphenyl ester derivatives as hypnotics |