| Patents for C07D 225 - Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom (1,649) |
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| 06/05/2008 | US20080132485 Amide substituted heterocylic compound; anticarcinogen; inducing apoptotic cell death, sensitizing cells to inducers of apoptosis |
| 05/27/2008 | US7378407 Geldanamycin compounds and method of use |
| 05/22/2008 | WO2008061134A1 Derivatives of 18-amino substituted analogs of the geldamycin hydroquinon with cytotoxic activity for the treatment of cancer |
| 05/22/2008 | CA2669820A1 Derivatives of 18-amino substituted analogs of the geldamycin hydroquinon with cytotoxic activity for the treatment of cancer |
| 05/21/2008 | EP1923061A1 Process for preparing 17-Allyl amino geldanamycin (17-AAG) and other ansamycins |
| 05/20/2008 | US7375217 Reduction of the benzoquinone moiety to form a hydroquinone, and salt formation, producing 17-ammonium hydroquinone ansamycin analogs with improved solubility and air stability; antiproliferative and anticarcinogenic agents |
| 05/15/2008 | WO2008056189A1 18, 21-didesoxymacbecin derivatives for the treatment of cancer |
| 05/15/2008 | WO2008056188A2 Novel compounds and methods for their production |
| 05/15/2008 | CA2669054A1 18, 21-didesoxymacbecin derivatives for the treatment of cancer |
| 05/15/2008 | CA2669047A1 Novel compounds and methods for their production |
| 05/13/2008 | US7371772 Bicyclic compound, production and use thereof |
| 05/08/2008 | WO2008034895A3 Ansamycin derivatives |
| 05/08/2008 | US20080108694 Inhibit the growth of or kill Rb negative cancer cells; inhibit the activity of Heat shock protein 90; antibiotics, antimalarial agents, anticancer agents, antitumor agents; cytotoxicity; to treat glioblastoma, lung cancer and retinoblastoma |
| 05/08/2008 | CA2667826A1 Inhibitors of histone deacetylase |
| 05/07/2008 | EP1918272A1 Pharmaceutically active compounds and methods of use |
| 05/06/2008 | US7368444 4-Hydroxy-1-toluenesulfonyl-2,3,4,5-tetrahydro-1H-1-benzazepine, for example; useful as the preventive and/or treatment medicine against diseases caused by stress |
| 05/06/2008 | US7368100 Backbone-substituted bifunctional DOTA ligands, complexes and compositions thereof, and methods of using same |
| 05/06/2008 | CA2327468C Semi-synthetic ecteinascidins |
| 04/30/2008 | CN100384834C Epothilone derivatives |
| 04/23/2008 | CN101166526A Method of treating multiple myeloma using 17-AAG or 17-AG or a prodrug of either in combination with a proteasome inhibitor |
| 04/22/2008 | US7361648 1-(4-{ethyl-[2-(4-methanesulfonylphenyl)-1-methylethyl]amino}butyl)-4-methanesulfonyl-[1,4]diazepan-2-one; repiratory system disorders: asthma and chronic obstructive pulmonary disease; nervous system, muscular,urogenital, gastrointestinal disorders; antiallergens; side effect reduction |
| 04/22/2008 | US7361647 hydroquinone derivatives of the Geldanamycin family; heat shock protein (chaperone) Hsp90 antagonist; improved solubility and air stability; antiproliferative and anticarcinogenic agents |
| 04/17/2008 | WO2008045668A1 Heterocyclic derived metalloprotease inhibitors |
| 04/17/2008 | WO2007143745A3 Substituted phenyl acetic acids as dp-2 antagonists |
| 04/17/2008 | CA2665629A1 Heterocyclic derived metalloprotease inhibitors |
| 04/10/2008 | WO2007144652A3 Parp inhibitors |
| 04/03/2008 | DE102006044472A1 Geldanamycin-Derivate Geldanamycin derivatives |
| 04/02/2008 | EP1904057A2 Methods of treatment using hydroquinone ansamycins |
| 04/02/2008 | CN100378079C Process for preparing 17-allyl amino geldanamycin (17-AAG) and other ansamycins |
| 03/27/2008 | WO2008034895A2 Ansamycin derivatives |
| 03/25/2008 | US7348290 Arene-ruthenium complexes immobilized on polymers, catalysts consisting of the complexes, and processes for organic syntheses with the same |
| 03/20/2008 | US20080071081 Using metal catalyst in presence of solvent and amine; salt formation of amine with released hydrogen chloride |
| 03/12/2008 | EP1897871A1 Benzenoid ansamycin derivative |
| 03/12/2008 | EP1896036A1 Anti-inflammatory agents |
| 03/12/2008 | EP1896012A2 Anti-inflammatory agents |
| 02/27/2008 | EP1435939B1 Process for preparing 17-allyl amino geldanamycin (17-aag) and other ansamycins |
| 02/27/2008 | CN101133029A Macrocyclic tertiary amine beta-secretase inhibitors for the treatment of alzheimer's disease |
| 02/20/2008 | EP1889839A1 Bicyclic compound, production and use as HIV inhibitors |
| 02/12/2008 | US7329746 Ring structures C6.C6.C13N and C6.C6.C12NO |
| 02/07/2008 | US20080031951 Compositions and methods for the inhibition of phospholipase A2 |
| 01/31/2008 | US20080027038 N-Acylated lipophilic amino acid derivatives |
| 01/29/2008 | US7323455 1,2,3,5-Tetrahydro-4,1-benzoxazepine derivatives: 4-methyl-5-(5-methyl-2-oxo-5-phenyl-1,2,3,5-tetrahydro-4,1-benzoxazepin-7-yl)thiophene-2-carbonitrile; contraceptives; hormone replacement therapy |
| 01/16/2008 | CN100361993C Method for total synthesizing bromization derivative pyrrole hetero ring alkaloid |
| 01/09/2008 | EP1876180A2 Semi-synthetic ecteinascidins |
| 01/09/2008 | EP1874297A1 Method of treating multiple myeloma using 17-aag or 17-ag or a prodrug of either in combination with a proteasome inhibitor |
| 01/03/2008 | WO2007128829A3 18,21-didesoxymacbecin derivatives for the treatment of cancer |
| 01/03/2008 | WO2007128827A8 17-oxymacbecin derivatives and their use in the treatment of cancer and/or b-cell malignancies |
| 12/27/2007 | US20070297980 Geldanamycin and Derivatives Inhibit Cancer Invasion and Identify Novel Targets |
| 12/25/2007 | US7311970 Cardiac pacemaker; surface treatment using superoxidase dismutase |
| 12/21/2007 | WO2007113266A3 Novel compounds and methods for their production |
| 12/21/2007 | WO2006036395A3 Inhibitors of akt activity |
| 12/19/2007 | EP1115693B9 SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL $i(TERTIARY)-HETEROALKYLAMINES USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY |
| 12/19/2007 | EP1032556B1 Pharmaceutically active compounds and methods of use |
| 12/13/2007 | US20070287829 Preparation of metallotexaphyrins |
| 12/13/2007 | CA2654784A1 Substituted phenylacetic acids as dp-2 antagonists |
| 12/12/2007 | EP1863769A2 Hsp90 inhibitors, methods of making and uses therefor |
| 11/29/2007 | WO2007113269A3 15-desmethoxymacbecin derivatives for the treatment of cancer diseases |
| 11/22/2007 | WO2007133945A2 Gerotor motor and brake assembly |
| 11/22/2007 | US20070270396 17-(Quaternary nitrogen(N-oxide)-alkylamino)-substituted; extracellular heat shock protein-90 inhibitors, anticarcinogenic agent; better bioavailability, less tixicity |
| 11/22/2007 | US20070269855 Recombinant polynucleotides encoding pro-geldanamycin producing polyketide synthases and accessory proteins, and uses thereof |
| 11/15/2007 | WO2007128829A2 18,21-didesoxymacbecin derivatives for the treatment of cancer |
| 11/15/2007 | WO2007128827A1 17-oxymacbecin derivatives and their use in the treatment of cancer and/or b-cell malignancies |
| 11/15/2007 | US20070265184 Process for preparing cyclododecatriene |
| 11/15/2007 | CA2651558A1 Novel compounds |
| 11/15/2007 | CA2651557A1 17-oxymacbecin derivatives and their use in the treatment of cancer and/or b-cell malignancies |
| 11/13/2007 | US7294631 Substituted 8′-pyri(MI)dinyl-dihydrospiro-[cycloalkylamine]-pyrimido[1,2-a]pyrimidin-6-one derivatives |
| 11/06/2007 | US7291727 Can be aligned to form an ordered architecture that can facilitate charge transport in the direction along the columns, processed to form a large area single crystalline thin film, and respond to external light irradiation; high-efficiency photovoltaic materials and organic light emitting devices |
| 11/01/2007 | WO2007122084A1 Layout of power semiconductor contacts on a cooling surface |
| 11/01/2007 | US20070255055 Epothilone derivatives |
| 11/01/2007 | US20070254869 modulators of Cholesterol ester transfer protein activity, such as 5-[Acetyl-(3,5-bis-trifluoromethyl-benzyl)-amino]-7-trifluoromethyl-2,3,4,5-tetrahydro-benzo[b]azepine-1-carboxylic acid isopropyl ester, for treating or preventing cardiovascular disorders |
| 10/25/2007 | WO2007120953A2 Attack and disaster resilient cellular storage systems and methods |
| 10/16/2007 | US7282493 Analogs of benzoquinone-containing ansamycins and methods of use thereof |
| 10/11/2007 | WO2007113270A1 15-o-desmethylmacbecin derivatives and their use in the treatment of cancer or b-cell malignancies |
| 10/11/2007 | WO2007113269A2 15-desmethoxymacbecin derivatives for the treatment of cancer diseases |
| 10/11/2007 | WO2007113268A1 4, 5-dihydromacbecin derivatives and their use in the treatment of cancer or b-cell malignancies. |
| 10/09/2007 | US7279573 Benzodiazepine derivatives that may be fused to a pyrroline or piperidine ring; e.g., N-[1 (R)-(3-Aminopropylcarbamoyl)-2-(naphthalen-2-yl)ethyl]-3-(5,11-dioxo-2,3-dihydro-1H-(11aS)-pyrrolo[2,1-c][1,4]benzodiazepin-10-yl)propionamide; increasing levels of endogenous growth hormones in humans and animals |
| 09/27/2007 | WO2005112952A3 Geldanamycin compounds and method of use |
| 09/20/2007 | WO2007105482A1 Process for production of amides or lactams |
| 09/20/2007 | US20070218010 Contrast Agents for Magnetic Resonance Imaging |
| 09/18/2007 | US7271160 Firt and second hsp(heat shock protein)-binding moieties joined by a linker, which bind to the pocket of hsp90 with which ansamycin antibiotics bind; linked geldanamycin, for example; treating cancer |
| 08/30/2007 | US20070203110 17-Allylamino-17-demethoxygeldanamycin polymorphs and formulations |
| 08/21/2007 | US7259156 17-(Quaternary amino-, phosphono- phosphino-, sulfo-, or carboxy-alkylamino)-substituted; extracellular heat shock protein-90 inhibitors, used as anticancer agents |
| 08/15/2007 | EP1067933B1 Semi-synthetic ecteinascidins |
| 08/08/2007 | CN101012196A Fragrant geldanamycin derivative and its preparing method and use |
| 08/02/2007 | US20070179293 Method for the production of o-substituted hydroxylamine compounds |
| 07/26/2007 | WO2007059116A3 Geldanamycin derivatives and pharmaceutical compositions thereof |
| 07/24/2007 | US7247756 1,4-disubstituted benzenes as insecticides |
| 07/18/2007 | CN100999496A Compound of polyphenols with aza-containing heterocyclic modified and use thereof |
| 07/18/2007 | CN100999495A Compound of styryl with axa-containing heterocyclic modified and use thereof |
| 07/11/2007 | CN1997632A Geldanamycin and derivatives inhibit cancer invasion and identify novel targets |
| 07/11/2007 | CN1995020A Radioactive iodine-17- allylamino-17-demethoxygeldanamycin and its preparation method |
| 07/10/2007 | US7241755 E.g., pentamethyl-16-[1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-1-aza-13(Z)-cyclohexadecene-2,6-dione and 4S-[4R*,7S*,8R*,9R*,15R*(E)]]-4,8-dihydroxy-5,5,7,9,13,16-hexamethyl-16-[1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-1-oxa-13-cyclohexadecene-2,6-dione; antiproliferative agents |
| 07/10/2007 | US7241754 2-Desmethyl ansamycin compounds |
| 07/05/2007 | WO2007074347A1 21-deoxymacbecin analogues useful as antitumor agents |
| 07/05/2007 | WO2006098761A3 Hsp90 inhibitors, methods of making and uses therefor |
| 07/05/2007 | WO2006055434A3 Macrocyclic tertiary amine beta-secretase inhibitors for the treatment of alzheimer's disease |
| 07/05/2007 | US20070152189 Light-harvesting discotic liquid crystalline porphyrins and metal complexes |
| 07/05/2007 | CA2628728A1 21-deoxymacbecin analogues useful as antitumor agents |
| 06/27/2007 | CN1986546A Geldanamycin derivative and its preparing method and use |
| 06/14/2007 | WO2007066492A1 Process for production of lactam |