Patents
Patents for C07D 217 - Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems (11,865)
01/1995
01/31/1995US5385898 Hypertensive agents; cardiovascular disorders; renin inhibitors; glaucoma
01/26/1995WO1994026730A3 Novel aromatic nitro and nitroso compounds and their metabolites useful as anti-viral and anti-tumor agents
01/25/1995EP0635493A2 Process for the preparationof a beta-aminoalcohol
01/25/1995EP0635492A1 Glycoprotein IIb/IIIa antagonists
01/25/1995EP0635488A2 Novel process for preparing azetidinone compound and novel starting compound therefor
01/25/1995EP0634997A1 Preparation of substituted guanidines
01/25/1995CN1097737A Substituted benzoylguanide preparation and pharmaceutical application of same
01/24/1995US5384322 Nitrogen-containing bicyclic compounds and pharmaceutical compositions thereof
01/23/1995CA2128348A1 Glycoprotein iib/iiia antagonists
01/18/1995EP0634402A1 Isochinolinone derivatives, their production and use
01/18/1995EP0634401A1 MDR reversal agents
01/17/1995CA2128139A1 Mdr reversal agents
01/15/1995CA2128055A1 Heterocyclic compounds, their production and use
01/11/1995CN1097192A Retroviral protease inhibitors
01/10/1995US5380849 Process for optically pure decahydroisoqiunolines
01/05/1995WO1995000497A1 Inhibitors of farnesyl-protein transferase
01/05/1995WO1995000489A1 Isoquinoline derivatives as therapeutic agents
01/05/1995CA2165823A1 Isoquinoline derivatives as therapeutic agents
01/05/1995CA2165176A1 Inhibitors of farnesyl-protein transferase
01/04/1995CN1097006A O-aryl ethers of morphinans
01/03/1995US5378849 Substituted tetrahydroisoquinoline compounds, and process for producing them, and composition containing them
01/03/1995US5378843 5,6-disubstituted-3-pyridylmethyl ammonium halide compounds useful for the preparation of 5-(substituted methyl)-2,3-pyridinedicarboxylic acids
12/1994
12/28/1994CN1096780A Therapeutic agents
12/22/1994WO1994029273A1 Bicyclic fibrinogen antagonists
12/21/1994EP0424525B1 Novel amines and their use
12/21/1994CN1096515A New peptides
12/14/1994EP0628543A1 Substituted benzoylguanidines, process for their preparation, their use as medicament or diagnostic agent, as well as a medicament containing them
12/14/1994EP0628030A1 2,3,4,5-TETRAHYDRO-1H --3-BENZAZEPINES HAVING ANTI-PSYCHOTIC ACTIVITY, AND SYNTHESIS OF $g(a)-SUBSTITUTED-ARYLACETAMIDES
12/14/1994EP0628027A1 Azo oxime ethers and their use as fungicides
12/08/1994WO1994027971A1 Anti-arrhythmic n-substituted 3-benzazepines or isoquinolines
12/08/1994WO1994027969A1 Isoquinolinetrione derivatives as herbicides
12/08/1994WO1994027591A1 Therapeutic substituted guanidines
12/07/1994EP0627422A2 Process for the preparation of carboxamides of nitrogen-containing aromatic heterocycles, as well as their use
12/07/1994EP0626949A1 Antipsychotic nitrogen-containing bicyclic compounds
12/07/1994EP0626947A1 Hydroisoindolines and hydroisoquinolines as psychotropic drugs
12/04/1994CA2125021A1 Alpha-heteroaryloxymethyl ketones as interleukin-1 beta converting enzyme inhibitors
11/1994
11/24/1994WO1994026730A2 Novel aromatic nitro and nitroso compounds and their metabolites useful as anti-viral and anti-tumor agents
11/24/1994WO1994026717A1 Hiv protease inhibitors useful for the treatment of aids
11/24/1994CA2162556A1 Novel aromatic nitro and nitroso compounds and their metabolites useful as anti-viral and anti-tumor agents
11/24/1994CA2161334A1 Hiv protease inhibitors useful in the treatment of aids
11/23/1994EP0625507A2 Urea derivatives and their use as acat inhibitors
11/22/1994CA2123728A1 Urea derivatives and their use as acat inhibitors
11/15/1994US5364882 Acyloenzyme a: cholesterol acyltransferase inhibitors, anticholesterol
11/15/1994CA1333067C Ring substituted isoquinolines
11/09/1994EP0623592A1 Peptide analogs as irreversible interleukin-1beta protease inhibitors
11/08/1994US5362912 Process for the preparation of a substituted diaminodiol
11/08/1994US5362877 Reacting a carbamate containing compound, paraformaldehyde or trioxane and mercapto substituted heterocyclic compound
11/08/1994US5362736 Alkoxy derivatives for cardiovascular disorders
11/08/1994CA1332944C Isoquinoline derivatives, their preparation and their use
11/02/1994EP0561863B1 Amidic derivatives of glutamic, aspartic and 2-amino adipic acids with antigastrin activity
11/02/1994CN1094399A Inhibitors of HIV protease useful for the treatment of aids
11/01/1994US5360908 Isomeriation, assymetric hydrogenation
10/1994
10/30/1994CA2122227A1 Peptide analogs as irreversible interleukin-1.beta. protease inhibitors
10/27/1994WO1994024108A1 Michellamines useful as antiviral agents
10/27/1994CA2160869A1 Michellamines useful as antiviral agents
10/26/1994EP0620820A1 Novel substituted oxazinoisoquinoline derivatives, pharmaceutical compositions containing them and process for preparing same
10/25/1994US5359074 Process for the preparation of racemic and optically active 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid and its precursors
10/25/1994US5359072 Nonlinearly optically active compounds
10/25/1994US5358957 Agrochemicals; pesticides
10/13/1994WO1994022863A1 Second messenger cell signaling inhibitors
10/13/1994WO1994022846A1 Compounds enhancing antitumor activity of other cytotoxic agents
10/13/1994WO1994022812A1 Imino-substituted phenylacetic acid amides, their preparation and fungicides containing them
10/13/1994CA2158066A1 Imino-substituted phenylacetamides, their preparation and fungicides containing them
10/12/1994EP0619296A1 Phenylalkan(en)oic acids with leukotriene B4 antagonistic activity
10/12/1994EP0618889A1 Tri-substituted phenyl derivatives and processes for their preparation
10/12/1994EP0552158B1 Derivatives of aspartic acid and glutamic acid having anti-cholecystokinin activity
10/12/1994EP0541802B1 Diphenylmethylpiperazine derivative
10/11/1994US5354866 Treating HIV infections
10/11/1994US5354763 Smooth muscle relaxants
10/11/1994US5354749 For treating arterial hypertension and atheroschlerosis
10/11/1994CA1332415C 1,2,3,4-tetrahydroisoquinoline antiarrhythmic agents
10/05/1994EP0618221A2 Heterocyclic inhibitors of farnesyl protein transferase
10/05/1994EP0618197A1 Synthesis of CIS-decahydroisoquinoline-3-carboxylic acids
10/05/1994EP0618196A1 Stereocontrolled synthesis of cis-bicyclic compounds
10/05/1994CN1026046C Compound killing fungus and preparation of same
10/03/1994CA2118985A1 Heterocyclic inhibitors of farnesyl protein transferase
10/01/1994CA2119732A1 Stereocontrolled synthesis of cis-bicyclic compounds
10/01/1994CA2119730A1 Synthesis of cis-decahydroisoquinoline-3-carboxylic acids
09/1994
09/29/1994WO1994021621A1 Guanidine derivatives useful in therapy
09/28/1994EP0617022A1 6,7, dialkoxy-3,4-dihydroisoquinolin-8-ol, process for preparation thereof and process for preparation of 6,7-dialkoxy-1,2,3,4-tetrahydroisoquinolin-8-ol using the compound
09/28/1994EP0616532A1 Use of peripheral-type benzodiazepine sites for treatment of cns trauma or disease
09/27/1994US5350761 Indolyl substituted hydroxylamine derivatives
09/27/1994US5350759 Bis-aryl amide antagonists of platelet activating factor
09/27/1994US5350757 Substituted 1,2,3,4-tetrahydroisoquinolines with angiotensin II receptor antagonist properties
09/21/1994EP0615448A1 Sex steroid activity inhibitors
09/21/1994CN1092410A Inhibitors of HIV protease useful for the treatment of aids
09/15/1994WO1994020454A1 New derivatives of glutamic and aspartic acids, a method of preparing them, and their use as drugs for enhancing memory and learning
09/07/1994EP0613879A1 Phellodendrine analogs and allergy type iv suppressor containing the same as active ingredient
09/07/1994EP0514420B1 Hydrazine derivatives
09/07/1994EP0485583B1 Use of tetrahydroisoquinoline derivatives for preparing antitumoral drugs
09/06/1994US5344978 Fungicides
09/06/1994US5344843 Carnitine acryltransferase enzyme inhibitors as antiischemic agents and for cardiovascular disorders
08/1994
08/31/1994EP0612730A1 O-aryl ethers of morphinans
08/31/1994EP0612723A1 Substituted benzoylguanidines, process for their preparation, their use as medicament, as inhibitor of the cellular Na+/H+ exchange or as diagnostic agent and medicament containing them
08/26/1994CA2116294A1 6,7-dialkoxy-3,4-dihydroisoquinolin-8-ol, process for preparation thereof and process for preparation of 6,7-dialkoxy-1,2,3,4-tetrahydroisoquinolin-8-ol using the compound
08/24/1994EP0611774A1 Production of amides and peptides without racemization in the presence of catalytic amounts of a N-hydroxy-compound
08/24/1994CN1091129A Excitatory amino acid receptor antagonists
08/23/1994US5340820 Useful for treatment of ocular diseases, angina pectoris, hypertension and arrhythmia
08/23/1994US5340811 Bronchodilator agent
08/23/1994CA1331615C Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids