Patents
Patents for C07D 217 - Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems (11,865)
05/1990
05/09/1990EP0366669A1 Malic acid derivative containing renin inhibiting peptides
05/08/1990US4923993 Unsaturated hydrazone and halide, diels-alder
05/02/1990EP0366273A1 Benzopyran derivatives with smooth muscle relaxant activity
05/01/1990US4921955 Process for the synthesis of 1-substituted imidazole-5-carboxylic acids and carboxylic acid derivatives
04/1990
04/25/1990EP0365324A1 Spiro-isoquinoline-pyrrolidine tetrones and analogs thereof useful as aldose reductase inhibitors
04/18/1990EP0364313A1 Non-linearly optically active organic compounds and electrooptical devices containing them
04/18/1990EP0363671A2 Use of ACE inhibitors against the formation of neo-intima after vascular infliction
04/17/1990US4918073 Diarylalkyl-substituted alkylamines and medicaments containing them
04/17/1990CA1267903C Trifluoromethanesulfonates and a process for their preparation
04/11/1990EP0363212A2 Novel heterocyclic compounds and anticancer-drug reinforcing agents containing them as effective components
04/10/1990US4916156 Antiseptic or preservatives in pharmacy, cosmetology or food stuff
03/1990
03/27/1990US4912225 Benzothiazolones, and their production and use
03/27/1990US4912221 Hydrogenating in presence of a cationic catalyst
03/27/1990US4912220 Mixing a nitroaryl compound with an unsaturated silane under anhydrous conditions; adding a fluoride compound and an electrophilic compound
03/27/1990US4912115 Heteroaromatic amine derivatives, pharmaceutical compositions containing these compounds and processes for preparing them
03/27/1990CA1267146A1 2-naphthalens substituted quinoline compounds
03/21/1990EP0359112A2 Carbazate derivatives, their production and use
03/21/1990EP0358957A1 Fused tetrahydropyridineacetic acid derivatives, process for their preparation, and use of such compounds for the cardioprotection
03/20/1990CA1266864A1 Radiopharmaceuticals and chelating agents useful in their preparation
03/13/1990US4908361 Pharmaceuticals
03/08/1990WO1990002119A1 1,2,3,4-tetrahydroisoquinoline derivatives
03/08/1990WO1990002112A1 Substituted aryl ureas as high potency sweeteners
02/1990
02/28/1990EP0355819A1 Substituted aryl ureas as high potency sweeteners
02/28/1990EP0355750A1 Substituted dihydroisoquinolinones and related compounds as potentiators of the lethal effects of radiation and certain chemotherapeutic agents; selected compounds, analogs and process
02/27/1990US4904675 Phamacologically active 5-carboxy-2-(5-tetrazolyl) pyridines
02/27/1990US4904300 Imidazole derivatives
02/20/1990US4902817 Process for the synthesis of alpha n alkylated amino acids and esters thereof, application to the synthesis of carboxyalkyl dipeptides
02/20/1990US4902695 Isoquinoline derivatives; nervous system disorders
02/14/1990EP0354553A2 Aryl cyanoguanidines: potassium channel activators and method of making same
02/14/1990CN1039591A Enamine quaternary compounds, methods of making and their use as muscle relaxants
02/13/1990US4900823 Phenyl ketone derivatives
02/13/1990CA1265806A1 1-cyclohexyl-3,4-dihydroisoquinoline derivatives, process for their preparation and pharmaceutical compositions containing them
02/08/1990WO1990001025A1 Enamine quaternary compounds, methods of making and their use as muscle relaxants
02/06/1990US4898876 Benzoylpiperazine esters and a process for their production
01/1990
01/30/1990US4897391 Tricyclic anti-allergy, antiinflammatory and anti-hyperproliferative compounds
01/30/1990CA1265141A1 1-¬bis(hydroxymethyl)-methyl|-2-substituted- isoquinoline derivatives and pharmaceutical compositions containing them
01/02/1990CA1264160A1 Amides, their preparation, and pharmaceuticals containing same
12/1989
12/26/1989US4889934 Organic mixed complex
12/26/1989US4889851 Bone disorders
12/20/1989EP0346847A2 Amino acid derivatives
12/20/1989EP0174342B1 Brain-specific analogues of centrally acting amines
11/1989
11/23/1989EP0343050A1 6-Phenyl-3-piperazinylalkyl 1H,3H-pyrimidinedione-2,4 derivatives, their preparation and their use in therapy
11/21/1989US4882339 Antiinflammatory, antiallergens
11/21/1989US4882338 Substituted isoquinoline derivatives and anti-ulcer agents
11/15/1989EP0341562A1 Process for preparing(+)-and(-)-beta-[(2-amino-1-naphthalenyl)thio]-alpha-hydroxy-4-methoxy-benzenepropanoic acid
11/14/1989US4880817 O-functionalized derivatives of substituted isoquinolin-3-ols having cardiotonic and/or phosphodiesterase fraction III inhibiting properties and/or renal vasodilating properties
11/09/1989DE3814361A1 Process for an improved alkaline oxidation
11/02/1989EP0339496A2 Aminoguanidine derivatives
11/01/1989CN1036758A Bicyclic amine compound and process for preparation thereof
10/1989
10/25/1989EP0338877A1 Selective binding compounds for 5-hydroxytryptamine 1-A-receptors and pharmaceutical compositions containing them
10/25/1989EP0338352A2 Salicylic acid derivatives
10/24/1989US4876261 Urogenital disorders; nephrovascular dilators; act on dopamine receptor
10/18/1989EP0195817B1 Carboxyalkyldipeptides, their preparation and pharmaceutical compositions containing them
10/11/1989EP0336228A1 Tetrahydroisoquinolines and tetrahydrobenzazepines and a process for the preparation thereof
10/11/1989EP0336142A2 Novel antagonists of platelet activating factor
10/03/1989US4871846 Cyclization of quinoline or isoquinoline derivatives with amide component
10/03/1989US4871735 Naphthyl derivatives, pharmaceutical compositions containing these compounds and processes for preparing them
09/1989
09/26/1989CA1261332A1 Ester substituted aminoalkanoylureido amino and imino acid and ester compounds
09/26/1989CA1261331A1 1-heteroaryl-4-aryl-pyrazolin-5-ones
09/26/1989CA1260468A1 Compounds with histamine h.sub.2-receptor antagonistic activities
09/21/1989WO1989008450A1 Squalene oxide cyclase inhibitors and therapeutic use thereof
09/19/1989US4868304 Synthesis of nitrogen heterocycles
09/13/1989CN1035502A 2-amino-tetrahydro-isoquinoline derivatives and process for preparing them, pharmaceutical containing them
09/12/1989US4866173 Hypotensive agents
09/12/1989US4866087 Hypotensive agents
09/12/1989US4866076 Thromboxane antagonists
09/06/1989EP0330910A1 Propane derivatives
09/05/1989US4864058 Process for making optically active naphtho[1,2-b][1,4]thiazepin-4(5H)-ones
09/05/1989US4863948 Isoindolinone sulfonamide anti-arrhythmic agents
09/05/1989US4863946 Hypoglycemic and hypotensive agents
09/05/1989US4863940 N-acetonyl-substituted amides and phytopathogenic fungicidal use thereof
09/05/1989US4863932 Squalene oxide cyclase inhibitors and therapeutic use thereof
09/05/1989US4863918 Enamine quaternary compounds, methods of making and their use as muscle relaxants
09/05/1989CA1259070A1 Substituted 2-¬monoannelated(3,4-,4,5-, and 5,6-)- pyridylalkylenesulfinyl|-benzimidazoles
08/1989
08/30/1989EP0330469A2 Tetrahydroisoquinoline derivatives
08/30/1989EP0330468A2 Use of heterocyclic derivatives as kappa-opioid receptor agonists in the treatment of cerebral ischaemia
08/30/1989EP0330360A1 1,2,3,4-Tetrahydroisoquinolines, processes for their preparation, and their use as kappa-receptor agonists
08/29/1989US4861888 Process for the preparation of 3,4-dihydroisoquinoline
08/15/1989US4857648 Isoquinoline derivatives
08/15/1989CA1258456A1 Aryl or hetero-aryl derivatives of 1-hydroxy-pentane or 1-hydroxy-hexane for treating inflammation and allergies
08/08/1989US4855476 3,4-dibenzyloxy-5-fluorobenzylcyanide from 2-fluoro-6-methoxyp henol
08/02/1989EP0326386A2 Isoquinolinones
08/01/1989US4853400 Fungicides
08/01/1989CA1258148A1 Process for the preparation of n-alkylated dipeptides and their esters
07/1989
07/25/1989US4851537 Process for preparing N-acyltetrahydroisoquinoline
07/25/1989US4851399 Isoquinoline derivatives and their use as anti-cancer agents
07/20/1989DE3900233A1 Isoquinoline derivatives and their use
07/19/1989EP0324184A2 2-Amino-1,2,3,4-tetrahydroisoquinoline derivatives, method for their preparation and their use as medicines
07/11/1989US4847264 Antiulcer agents, antisecretory agents
07/11/1989US4846880 2-(Dichloroacetyl)-3-substituted-1,2,3,4-tetrahydroisoquinolines as herbicide antidotes
07/05/1989CN1033622A Heterocyclic insecticides
07/04/1989US4845228 Pyridyl-cyclohexanone compounds
06/1989
06/27/1989US4843081 Aryl and heteroaryl substituted cycloalkyl compounds
06/27/1989US4843077 Isoquinoline derivatives having renal vasodilating properties and/or cardiotonic properties and/or phosphodiesterase inhibiting properties
06/21/1989EP0321296A1 Lipid derivatives their preparation and use
06/21/1989EP0321274A1 Derivatives of thioformamide
06/21/1989EP0320753A2 Derivatives of cyclic aminoacids, their preparation, compounds containing them, and their use
06/15/1989WO1989005289A1 Novel amines and their use
05/1989
05/31/1989EP0317991A2 1-Aryl-3-quinoline- and 1-aryl-3-isoquinoline-carboxamides, a process for their preparation and their use as medicaments
05/24/1989EP0317259A2 Heterocyclic insecticides