Patents
Patents for C07C 257 - Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines (2,984)
02/2004
02/19/2004WO2004014844A2 Aryl and heteroaryl compounds and methods to modulate coagulation
02/19/2004WO2002091989A3 Antiviral therapies using polyamine or polyamine analog-amino acid conjugates
02/19/2004US20040034231 Amidinophenyl-4-aminoacetic acid derivative is useful for treating diseases such as thrombosis, apoplexy, cardiac infarction, inflammation and arteriosclerosis, which are associated with coagulation factors xa, IXa and thrombin
02/19/2004US20040034027 E.g.N-(carbamimidoylphenyl)-N'-((1-(4-nitrophenyl)ethyl-2-phenyl -malonamide formate; reversible enzyme inhibitors of blood factor VIIa; a strong antithrombotic to treat thrombo-embolic diseases and restenoses; cardiovascular disorders
02/19/2004CA2493008A1 Aryl and heteroaryl compounds and methods to modulate coagulation
02/18/2004CN1476424A 萘衍生物 Naphthalene Derivatives
02/12/2004WO2003097582A3 Synthesis of benzonitriles and benzimidates
02/12/2004US20040029720 Supported group 8-10 transition metal olefin polymerization catalysts
02/11/2004CN1474805A 2-amino-2-alkyl-5-heptenoic and heptynoic acid derivatives useful as nitric oxide synthase inhibitors
02/11/2004CN1474804A 2-amino-2-alkyl-4-hexenoic and hexynoic acid derivatives useful as nitric oxide synthase inhibitors
02/10/2004CA2101821C Process for the production of 2-halo-4,6-dialkoxypyrimidines
02/05/2004WO2003084938A3 Pyrimidone derivatives useful for the treatment of inflammatin and immunological diseases
02/05/2004US20040024224 Synthesis of 2-alkyl amino acids
02/04/2004EP0813525B9 Benzamidine derivatives their preparation and their use as anti-coagulants
02/03/2004US6686484 Anticoagulants; serine protease inhibitor
02/03/2004CA2084109C Novel process for preparing 4-amino-5-hexanoic acid
01/2004
01/28/2004EP1383731A1 Biaryl compounds as serine protease inhibitors
01/27/2004US6683215 N-(4-carbamimidoyl-phenyl)-glycine derivatives
01/27/2004US6683182 Method for producing lamotrigine from α-oxo-2,3-dichlorophenyl acetamidino-aminoguanidino hydrazone by ring closure reaction
01/22/2004DE10230311A1 Verfahren zur Katalysator-freien Herstellung von O-Alkyl-N-cyanformimidaten Process for the catalyst-free production of O-alkyl-N-cyanformimidaten
01/15/2004WO2004005244A1 Method for carrying out the catalyst-free production of o-alkyl-n-cyanoformimidates
01/15/2004WO2003084936A8 Amino substituted pyrimidinone derivatives useful in the treatment of inflammation and immunological
01/14/2004CN1134423C Adhesion receptor antagonists
01/14/2004CN1134264C Antithrombotic agents
01/13/2004US6677369 Antithrombotic agents
01/13/2004CA2417435C Method for producing lamotrigine from alpha-oxo-2,3-dichlorophenyl acetamidino-aminoguanidino hydrazone by ring closure reaction
01/08/2004WO2003064378A3 Novel compounds that inhibit factor xa activity
01/08/2004US20040006224 Synthesis of 2-alkyl amino acids
01/08/2004US20040006092 Amidine derivatives for treating amyloidosis
01/07/2004EP1377543A1 Oxalic acid derivatives
01/07/2004EP1377290A2 Malonyl-coa decarboxylase inhibitors useful as metabolic modulators
01/06/2004US6673338 Nitric oxide-releasing imidate and thioimidate diazeniumdiolates, compositions, uses thereof and method of making same
01/02/2004EP1373194A1 BENZAMIDE INHIBITORS OF FACTOR Xa
01/01/2004US20040002613 Synthesis of benzonitriles from substituted benzoic acid
12/2003
12/25/2003US20030236435 Synthesis of 2-alkylcysteine via substituted thiazoline ester
12/25/2003US20030236434 Condensing cysteine with cabocyclic nitriles to form 2-arylthiazoline-4-carboxylic acid, then amidation, alkylation, hydrolyzing and optionally purifying to form 2-methylcysteine
12/25/2003US20030236426 Synthesis of benzimidate from benzoic acid
12/25/2003US20030236404 Synthesis of 2-alkylcysteine via phase transfer catalysis
12/25/2003US20030236231 Polycyclic aryl and heteroaryl substituted benzenes useful for selective inhibition of the coagulation cascade
12/23/2003CA2208032C Substituted amidinonaphthyl ester derivative
12/18/2003WO2003103598A2 Amidine derivatives for treating amyloidosis
12/18/2003WO2003024407A3 Inhibitors of rnase p proteins as antibacterial compounds
12/18/2003WO2002083030A3 Bifunctional energy-reversible acyl-compositions
12/18/2003US20030232987 Process for preparing xanthine phosphodiesterase V inhibitors and precursors thereof
12/18/2003US20030232813 Novel amino substituted pyrimidinone derivatives
12/18/2003US20030232789 Salicylamides as serine protease and factor xa inhibitors
12/18/2003CA2488493A1 Amidine derivatives for treating amyloidosis
12/17/2003EP1370522A1 Phenyl derivatives and their use in the treatment of thromboembolic disorders or tumours
12/17/2003EP1051392B1 Adamantanecarboximidamide derivatives and their use as nmda antagonists
12/16/2003US6664295 Agricultural composition for combatting fungi comprising a compound of the invention in admixture with a diluent or carrier
12/11/2003WO2003101992A1 Process for preparing xanthine phosphodiesterase v inhibitors and precursors thereof
12/11/2003WO2002062778A3 Anti-thrombotic compounds, production and use thereof as medicaments
12/11/2003US20030229231 Forming chelate compounds
12/11/2003US20030229072 Cyclic and acyclic amidines and pharmaceutical compositions containing them for use as progesterone receptor binning agents
12/11/2003US20030228978 Catalysts containing per-ortho aryl substituted aryl or heteroaryl substituted nitrogen donors
12/11/2003CA2483923A1 Process for preparing xanthine phosphodiesterase v inhibitors and precursors thereof
12/10/2003EP0971885B1 Process for preparing indane-like compounds
12/09/2003US6660885 Polycyclic aryl and heteroaryl substituted benzenes useful for selective inhibition of the coagulation cascade
12/09/2003US6660677 Supported group 8-10 transition metal olefin polymerization catalysts
12/04/2003US20030225287 Synthesis of chiral 2-alkyl amino acids
12/04/2003US20030225228 A catalyst for the polymerization of olefins, contains a titanium zirconium or hafnium complex of a dianionic bidentate ligand, (at least one of donor atoms of the ligand is a nitrogen atom substituted by a pyrrolyl group)
12/04/2003US20030225086 Polycyclic aryl and heteroaryl substituted 1,4-quinones useful for selective inhibition of the coagulation cascade
12/04/2003US20030225075 Novel pyrimidone derivatives
12/03/2003EP1366017A2 Non-natural basic amino acids, their preparation and use
12/03/2003EP1366016A2 Process for the preparation of arylethanoldiamines useful as agonists of the beta-3-adrenoceptor
12/02/2003US6656967 Aromatic fungicide compound containing N=C-G group wherein G= O, S, S=O, S(O)2 or N(NRR')
12/02/2003US6656869 Bidentate ligands bonded to nickel, palladium, cobalt, or iron, and optionally, one or more neutral Lewis acids
11/2003
11/27/2003WO2003097622A2 Synthesis of 2-alkylcysteines, 2-(hydroxylated phenyl)-4-alkylthiazoline-4-carboxylic acids and derivatives thereof
11/27/2003WO2003097582A2 Synthesis of benzonitriles and benzimidates
11/27/2003US20030220504 Forming a phenyl-thiazoles chemical intermediates for making antioxidants, ferrielectric liquid crystal dopant, picornaviral viricides, antiinflammatory agents, anti-asthma agents, and fibringoen antagonists
11/27/2003US20030220496 3-(optionally hydroxyl)-4-(cyclopropylcarbonyl)-cumene intermediate
11/26/2003EP1364985A1 Water-absorbent resin, process for production thereof, and water-absorbent resin composition
11/26/2003EP1363890A2 Melanocortin-4 receptor binding compounds and methods of use thereof
11/26/2003EP1363875A2 Novel benzamidine derivatives having anti-inflammatory and immunosuppressive activity
11/20/2003WO2003027076A3 1h-imidazole derivatives having cb1 agonistic, cb1 partial agonistic or cb1- antagonistic activity
11/13/2003WO2003093242A2 Substituted 5-membered polycyclic compounds useful for selective inhibition of the coagulation cascade
11/13/2003WO2003093224A1 Amidinylphenyl compounds and their use as fungicides
11/13/2003WO2003029200A3 Compounds useful as reversible inhibitors of cysteine proteases
11/13/2003US20030212071 Controlling blood coagulation
11/13/2003CA2462645A1 Substituted 5-membered polycyclic compounds useful for selective inhibition of the coagulation cascade
11/12/2003EP1361212A1 Peptide derivatives as antithrombotic agents
11/12/2003EP1206444B1 Compounds that inhibit tryptase activity
11/11/2003US6645992 Malonamid and malonamic ester derivatives with antithrombotic activity, their preparation, and their use
11/06/2003US20030207859 Novel substituted succinic acid metallo-beta-lactamase inhibitors and their use in treating bacterial infections
11/05/2003CN1126743C Substituted quinazoline derivatives
11/04/2003US6642252 Anticoagulants in treating and preventing cardiovascular diseases, as anti-inflammatory agents, and as metastasis inhibitors in treating cancer.
10/2003
10/30/2003WO2002064136A3 Malonyl-coa decarboxylase inhibitors useful as metabolic modulators
10/29/2003EP1357134A2 Catalyst compositions for the polymerization of olefins
10/29/2003EP1357108A1 Benzamidine derivatives and process for production thereof
10/22/2003EP1353662A2 Methods for the treatment of diseases using malonyl-coa decarbox ylase inhibitors
10/22/2003EP1140745B1 Colchinol derivatives as vascular damaging agents
10/16/2003WO2003084938A2 Pyrimidone derivatives useful for the treatment of inflammatin and immunological diseases
10/16/2003WO2003084937A2 Pyrimidinedione derivatives useful for the treatment of inflammation and immunological diseases
10/16/2003WO2003084936A2 Amino substituted pyrimidinone derivatives useful in the treatment of inflammation and immunological
10/16/2003WO2003084935A2 Diaryl pyrimidinone derivatives useful for the treatment of inflammation and immunogolical diseases
10/16/2003US20030195223 Antithrombotic agents
10/15/2003EP1351938A1 Phenyl derivatives
10/09/2003US20030191310 Cyclization of dihydrochloride salt of iminoguanidine derivative
10/09/2003US20030191255 Metal complexes of iminohydroxamic acids
10/08/2003CN1446804A Compound possessing fungicidal property and its usage
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