Patents
Patents for C07B 57 - Separation of optically-active organic compounds (3,737)
07/2003
07/09/2003EP1098871B1 alpha-AMINO ACID PHENYL ESTER DERIVATIVES
07/09/2003EP1064244B1 Method for separating a diphosphine diastereoisomers
07/09/2003CN1429188A Novel process for prepaing (+)-cis-sertraline
07/09/2003CN1113834C Separating agent for optical isomers, and its use and process for producing same
07/08/2003CA2153549C New benzothiadiazine derivative, process for preparing the same and pharmaceutical compositions containing said derivative
07/03/2003US20030125563 Asymmetric 1,4-reductions of and 1,4-additions to enoates and related systems
07/02/2003EP1322958A2 Selective binding materials
07/01/2003US6586436 Serotonergic agents
07/01/2003US6586434 Method for the preparation of tetrahydrobenzothiepines
06/2003
06/26/2003WO2003051861A1 Method for the preparation of escitalopram
06/26/2003WO2003051852A1 Intermediate and process for producing optically active compound from the intermediate
06/26/2003CA2470225A1 Method for the preparation of escitalopram
06/25/2003EP1135417B1 Polysaccharide chiral esters, one of the methods for preparing them and their uses for obtaining optically enriched acids or chiral chromatography
06/25/2003EP1091932B1 Chiral stationary phases for enantiomers separation and their preparation
06/19/2003WO2003050062A2 PRODUCTION OF CHIRALLY PURE α-AMINO ACIDS ADN N-SULFONYL α-AMINO ACIDS
06/19/2003CA2470111A1 Production of chirally pure .alpha.-amino acids and n-sulfonyl .alpha.-amino acids
06/18/2003EP1268584A4 Compositions and methods for selectively binding amines or amino acid enantiomers over their counter-enantiomers
06/12/2003WO2003048080A1 Methods for the separation of isomers
06/11/2003EP0718625B1 Separating agent
06/10/2003CA2133427C Enantiomeric 1-phenyl-2-(2-pyridinyl) ethylamine for the treatment of neurodegenerative disorders
06/05/2003WO2002088149A3 A process for manufacture of fosinopril sodium
06/05/2003US20030105364 Process for the preparation of optically pure or enriched racemic tetralone
06/04/2003EP1316542A1 3-amino-1-indanole, method of synthesizing the same and method of optical resolution
06/04/2003EP1315493A1 2-3-disubstituted quinuclidines as modulators of monoamine transporters and therapeutic and diagnostic methods based thereon
06/04/2003EP0773940B1 Process for synthesis of substituted sulphoxides
05/2003
05/28/2003EP1313547A2 Liquid membrane separation of enantiomers
05/28/2003EP0912528B1 Processes for producing phenoxy propionic acid derivatives
05/27/2003US6570036 Co-crystallization process
05/22/2003WO2003042132A1 Recovery and recycling of chiral tartaric acid resolving agents
05/22/2003WO2003041702A1 Production of pure stereoisomers of tricyclo[5.2.1.02.6]-dec-9-yl xanthogenate and medicaments therefrom
05/22/2003US20030097002 Enantioselective reactions using two-component chiral phase transfer catalysts in multiphasic systems
05/22/2003CA2465294A1 Recovery and recycling of chiral tartaric acid resolving agents
05/20/2003US6566298 Diphosphines
05/15/2003US20030092773 Process for the separation of the cis trans diasteroisomers of tramadol
05/15/2003US20030092142 Process for the preparation of chiral alpha-hydroxycarboxylic acids
05/14/2003EP1310477A2 Process for the preparation of chiral alpha-hydroxycarboxylic acids
05/14/2003EP1156864B1 Co-crystallization process
05/13/2003US6562967 Drug screening; purity
05/13/2003US6562966 Combining a racemic or a diastereomeric mixture of a chiral substrate with a nucleophile, in the presence of a chiral non-racemic catalyst
05/08/2003WO2003037840A1 Process for the preparation of optically pure or enriched racemic tetralone
05/08/2003WO2002100804A3 Novel use of sulfamic acids as resolving agent.
05/08/2003US20030088105 Process for the preparation of substituted thiazolines and their intermediates
05/08/2003US20030087950 New alpha-amino acid sulphonyl compounds
05/08/2003CA2464916A1 Process for the preparation of optically pure or enriched racemic tetralone
05/07/2003EP1307440A1 2,2-disubstituted 1,3-dioxolanes as antitussive agents
05/07/2003CA2411218A1 Process for the preparation of chiral alpha-hydroxycarboxylic acids
05/06/2003US6559338 Method for racemate splitting of 2-hydroxypropionic acids
05/06/2003US6559334 Polymers chromatographic separation of enantiomers
05/06/2003CA2126180C Isomerisation process
05/02/2003EP1305270A1 Kinetic resolutions of chiral 2- and 3-substituted carboxylic acids
04/2003
04/24/2003US20030078429 Diastereomeric salt between (R)-(+)- alpha -(4-(1,1-dimethylethyl or dimethylacetic acid or ester )phenyl)-4-hydroxydiphylphenylmethyl)-1 pipridinebutanol and either mandelic acid or di-para-toluoyltartaric acid
04/23/2003CN1413188A Resolution of intermediates in synthesis of substantially pure bicalutamide
04/22/2003US6552227 Process for preparing (+)-cis-sertraline
04/17/2003US20030073719 Chiral salt resolution
04/16/2003EP1302467A2 Process for the preparation of substituted thiazoline derivatives and their intermediate
04/16/2003EP1301452A2 Process for preparing (-)menthol and similar compounds
04/16/2003EP1067127B1 Novel beta-diketone compounds, beta-diketone compounds coordinated to metal, method of organic synthesis with these, and catalyst
04/09/2003EP1300391A1 Process for producing 3-amino-2-hydroxypropionic acid derivatives
04/08/2003US6545050 Aryl sulphonamide amino acid esters and analogues
04/02/2003CN1407967A Stereoselective synthesis of cyclic amino acids
04/02/2003CN1104416C Racemisation and asymmetric transformation process used in manufacture of levobupivacaine and analogues thereof
04/01/2003US6541668 Methods for preparing 3-arloxy-3-arylpropylamines and intermediates thereof
04/01/2003US6541634 Process for preparing growth hormone secretagogues
03/2003
03/27/2003US20030060656 Contacting organic compound with: an oxidizing agent, and catalyst comprising a metal and a chiral ligand, producing an oxidized organic compound and a single enantiomer of the organic compound
03/26/2003EP1294659A2 Process for isolating enantiomers of racemic cetamine
03/20/2003WO2003022784A1 Method for determining the enantiomer ratio trimethylcyclopentene derivatives
03/19/2003CN1403458A (8S,18S)-1,4,10,13,16-pentazatricyclo [16.3.0.0 4.8] heneicosane-9,17-diketone and its prepn process
03/18/2003US6534657 Chiral ferrocene phosphines and their use in asymmetric catalytic reactions
03/18/2003US6533936 Method for separation of optical isomers
03/12/2003EP1091954B1 Process for producing (8-chloro-3,10-dibromo-6,11-dihydro-5h-benzo 5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-piperidine
03/06/2003US20030045713 Diphosphines
03/05/2003EP1286984A2 Method for the preparation of tetrahydrobenzothiepines
03/05/2003EP1286982A2 Process for the preparation of benzoyl substituted bicylic compounds and chiral bnezopyran derivatives
03/05/2003EP1286951A1 Process for the separation of the cis trans diastereoisomers of tramadol
03/05/2003CN1400960A Packing material for separation of optical isomer and method of separating optical isomer with the same
03/05/2003CN1102561C Method of resolving racemic mixtures
03/04/2003US6528642 Alkenylated cyclodextrin compounds and polymers made tthereof ; made by reacting an alkenyl halide with cyclodextrin; use as support for separation of enantiomers, other isomers, and hydrophobic organic molecules, or as catalyst support
02/2003
02/27/2003WO2003016245A1 Chromatographic separation of enantiomers of protected amino acids via smb-method
02/26/2003CN1399687A Method for producing optically active amines
02/26/2003CN1102137C Method for splitting ibuprofen by two-component chiral reagent
02/25/2003US6525214 Contacting 2-(4-isobutylphenyl)propionic acid of high enantiomorph purity with sodium base; salt formation to form sodium ibuprofen; analgesics, antipyretics, antiinflammatory agents
02/25/2003CA2039401C Preparation of optically active norbornyl amine derivatives
02/18/2003US6521561 Main-group metal based asymmetric catalysts and applications thereof
02/13/2003WO2003011846A2 Process for the preparation of 5-substituted isobenzofurans
02/13/2003WO2003011842A1 Indane acetic acid derivatives and their use as pharmaceutical agents, intermediates, and method of preparation
02/13/2003WO2003011802A1 Iso-$g(b)-bisabolol as fragrance and aroma substance
02/13/2003WO2003011799A1 Kinetic resolutions of chirat 3- and 3-substituted carboxylic acids
02/13/2003CA2753329A1 Indane acetic acid derivatives and their use as pharmaceutical agents, intermediates, and method of preparation
02/13/2003CA2456166A1 Kinetic resolutions of chiral 2- and 3-substituted carboxylic acids
02/13/2003CA2456004A1 Process for the preparation of 5-substituted isobenzofurans
02/12/2003EP1104414B1 Enantioselective synthesis
02/11/2003US6518432 The invention relates to a novel process for the preparation of certain pharmaceutically active pyridyl compounds. NMDA receptor antagonist activity. The compound known as (S)-1-phenyl-2-(2- pyridyl)ethanamine is of particular
02/11/2003CA2041818C Separation of enantiomers of cimaterol, (-)-cimaterol and the use thereof as pharmaceutical compositions or as performance enhancers
02/05/2003EP1281707A1 Process for the preparation of 5-subtituted isobenzofurans
02/05/2003EP1280759A1 Optically active 2-aminotetralin derivatives, the processes for the preparation thereof and the therapeutical use of pharmaceutical compositions containing them
02/05/2003CN1394849A Acenaphthene derivative compound and its application
02/04/2003US6514407 Chloro-, hydroxy- and alkoxysilane derivatives of polysaccharides or oligosaccharides, polymerizable and cross-linkable, their synthesis and their use as sources of novel support materials
01/2003
01/30/2003US20030022901 Serotonergic agents
01/29/2003EP1192145A4 Process for preparing chiral cyclopropane carboxylic acids and acyl guanidines
01/23/2003US20030018083 Methods of treating and preventing pain, anxiety, and incontinence using derivatives of (-)-venlafaxine
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