Patents
Patents for C07B 57 - Separation of optically-active organic compounds (3,737)
11/2009
11/25/2009CN101585761A Industrial continuous preparation method of optically pure mandelic acid
11/24/2009CA2451124C Method for the preparation of escitalopram
11/19/2009WO2009137853A1 Enantioselective zwitterionic ion-exchanee material
11/18/2009CN101580482A Method for preparing rivastigmine hydrogen tartrate and application thereof
11/11/2009EP2114155A1 Enantiomers of amino-phenyl-acetic acid octadec- 9- (z) enyl ester, their salts and their uses
11/11/2009CN101578257A Process for production of hydroxyadamantaneamine
11/05/2009WO2009134737A1 Stereoselective synthesis of certain trifluoromethyl-substituted alcohols
11/05/2009CA2722285A1 Stereoselective synthesis of certain trifluoromethyl-substituted alcohols
11/04/2009EP2113769A1 Optical isomer separating filler
11/03/2009US7612214 Organic amine salts of glutamic acid derivatives and their application
10/2009
10/28/2009CN101568380A Organic-inorganic hybrid chiral sorbent and process for the preparation thereof
10/21/2009CN101560204A Antihypertensive drug cilazapril intermediate and preparation method thereof
10/21/2009CN101560184A N-chiral quaternary ammonium salt derived from amino acid and preparation method thereof
10/14/2009CN100548974C Extraction separating method of citalopram intermediate
10/14/2009CN100548939C Method for the separation of intermediates which may be used for the preparation of escitalopram
10/08/2009WO2009094569A3 Method for the enzymatic kinetic resolution of acyloxyalkyl thiocarbonates used for the synthesis of acyloxyalkyl carbamates
10/07/2009EP1686114B1 Process for producing optically active 2-alkylcysteine, derivative thereof, and processes for production
10/01/2009WO2009119700A1 Manufacturing method for a piperidine-3-ylcarbamate compound and optical resolution method therefor
09/2009
09/30/2009CN101544629A Method for separating enantiomers of rotigotine and trihexyphenidyl
09/30/2009CN101544597A Method for preparing amlodipine
09/29/2009CA2438891C Method for preparing optically active dihydropyrones
09/23/2009CN101538242A Synthetic method of Benazepril key intermediate S-amino substance
09/22/2009US7592480 Process for producing optically active carboxylic acid
09/17/2009WO2009113428A1 Method for producing optically active ester and method for producing optically active carboxylic acid
09/17/2009DE102008013500A1 Neue chirale Selektoren und stationäre Phasen zur Trennung von Enantiomerengemischen New chiral selectors and stationary phases for the separation of enantiomers
09/16/2009EP2099740A1 A process for the preparation of optically pure r (-) salbutamol and its pharmaceutically acceptable salts
09/08/2009CA2547733C Process for the preparation of enantiomerically enriched amino acids
09/03/2009WO2009107571A1 Method for optical resolution of alkylpiperidin-3-yl carbamate and intermediate therefor
09/01/2009US7582780 Method for the separation of intermediates which may be used for the preparation of escitalopram
08/2009
08/26/2009CN101514194A Method for preparing optical pure 6-Fluoro-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid
08/20/2009WO2009025791A3 Purification of armodafinil
08/19/2009CN100528850C Indane acetic acid derivatives and their use as pharmaceutical agents, intermediates, and method of preparation
08/19/2009CN100528828C Production method of racemiation3-hydroxy-3- (2-phenylethyl) hexanoic acid C1-6 alkyl ester
08/13/2009WO2009098935A1 Method for purifying optically active 1-(2-trifluoromethylphenyl)ethanol
08/13/2009DE69322992C5 Optisch reines Cis-oxalato(trans-l-1,2-Cyclohexandiamine)Pt(II) und Verfahren zur Auflösung von optischen Isomeren einer Platinkomplexverbindung Optically pure cis-oxalato (trans-l-1,2-Cyclohexandiamine) Pt (II) and methods for the resolution of optical isomers of a platinum complex compound
08/12/2009EP2088136A1 Process for production of hydroxyadamantaneamine
08/11/2009CA2367410C Novel process for the preparation of 1-phenyl-2-(2-piridyl)ethanamine
08/05/2009CN101501001A Processes for optical resolution of 1-phenyl-1,2,3,4-tetrahydroisoquinoline
08/05/2009CN101497575A Method for splitting S-(+)-o-chlorobenzene glycine methyl ester
07/2009
07/30/2009WO2009094569A2 Method for the enzymatic kinetic resolution of acyloxyalkyl thiocarbonates used for the synthesis of acyloxyalkyl carbamates
07/30/2009CA2706575A1 Enantiomerically resolving acyloxyalkyl thiocarbonates used in synthesizing acyloxyalkyl carbamate prodrugs
07/23/2009WO2009090957A1 Process for production of optically active amines
07/23/2009CA2711934A1 Process for production of optically active amines
07/16/2009WO2009087959A1 Optically active 2,2'-biphenol derivative and method for producing the same
07/14/2009USRE40851 3,3-diphenylpropylamines, their use and preparation
07/14/2009CA2464648C Process for resolution of tamsulosin
07/14/2009CA2362365C Method for the racemization of optically active amines
07/02/2009WO2009080708A1 Use of enantiopure n-sulphonyl pyroglutamic acid as resolving agent
07/02/2009US20090166292 Using a solvent-resistant column for use in high pressure liquid chromatography in which a polysaccharide derivative is used as an asymmetry recognition agent and based on an elution time of a first peak obtained by a gradient analysis; two component solvent system; isocratic conditions
06/2009
06/30/2009CA2254693C Process for the preparation of aminoalcohol derivatives and their further conversion to (1r,4s)-4-((2-amino-6-chloro-5-formamido-4-pyrimidinyl)amino)-2-cyclopentenyl-1-methanol
06/18/2009WO2009075359A1 Method of separating isomers of chiral substances and apparatus therefor
06/10/2009EP2066440A1 Organic-inorganic hybrid chiral sorbent and process for the preparation thereof
06/09/2009CA2355720C New substituted 3-phenoxy and 3-phenylalkyloxy-2-phenyl-propylamines
06/04/2009WO2009067904A1 Methods for resolution of the mixture of the optical isomers, especially the racemate of pinocembrin
06/04/2009CA2703927A1 Method for resolution of a mixture of pinocembrin optical isomers, especially a pinocembrin racemate
06/03/2009EP2065365A2 Functional monomers for molecular recognition and catalysis
06/02/2009CA2436185C Method for obtaining 4-(n-alkylamine)-5, 6-dihydro-4h-thieno-(2,3-b)-thiopyran-2-sulfamide-7, 7-dioxides and intermediate products
06/02/2009CA2362185C Methods for preparing 3-aryloxy-3-arylpropylamines and intermediates thereof
05/2009
05/27/2009CN101440079A Process for the preparation of racemic citalopram and/or S- or R-citalopram
05/27/2009CN101440056A Method for splitting docetaxel side chain intermediate
05/26/2009US7537933 quick and reliable; capillary gas chromatography; stationary phase contains a cyclodextrin derivatives and polysiloxanes
05/20/2009EP2060588A1 Polysaccharide derivative and separating agent for optical isomer containing the same
05/20/2009CN201241044Y Tandem continuous multilevel chiral disassemble apparatus
05/20/2009CN101434552A Method for splitting 4,5- dimethoxy-1-(methyl amino methyl)-benzocyclobutane
05/13/2009CN101429186A Split method for pinocembrin racemate
05/13/2009CN101429180A Process for producing S-tetrahydrochysene furoic acid
05/12/2009CA2261453C Process for the preparation of an optically active indoline-2-carboxylic acid or derivative thereof
05/07/2009WO2008038300A8 Organic-inorganic hybrid chiral sorbent and process for the preparation thereof
05/07/2009WO2006027798A3 A process for preparation of an antidepressant compound
05/05/2009CA2448281C Optical resolution of (1-benzyl-4-methylpiperidin-3-yl)-methylamine and the use thereof for the preparation of pyrrolo 2,3-pyrimidine derivatives as protein kinases inhibitors
04/2009
04/23/2009WO2007038277A3 Resolution of alpha-(phenoxy) phenylacetic acid derivatives with naphthyl-alkylamines
04/22/2009CN101412680A Preparation of high-purity eptazocine intermediate
04/16/2009WO2009047408A1 Continuous crystallisation method
04/15/2009EP2046724A1 Process for the preparation of (1r,2r)-3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol
04/15/2009EP1446372B1 Recovery and recycling of chiral tartaric acid resolving agents
04/09/2009CA2701114A1 Production of monatin stereoisomers
04/08/2009EP1299426B1 Improved microgels and films
04/07/2009CA2256828C Process for the manufacture of bis(phosphine oxide)-and bis(phosphonate)- compounds
03/2009
03/25/2009EP1934159B1 Method for fractionating stereoisomeric compounds
03/25/2009CN101395104A An improved process for the preparation of armodafinil
03/18/2009CN101386583A Resolution of escitalopram
03/11/2009EP1611111B1 Process for resolving 2,4-diamino-3,6-dihydro-1,3,5-triazines, useful for the treatment of disorders associated with insulin resistance syndrome
03/04/2009CN101379029A A process for resolving racemic mixtures and a diastereoisomeric complex of a resolving agent and an enantiomer of interest
02/2009
02/26/2009WO2009025791A2 Purification of armodafinil
02/26/2009WO2009025169A1 Method for purification of optically active α-fluorocarboxylic acid esters
02/25/2009CN100463892C Resolution process for salicylic acid and its isomer using hydrotalcite
02/19/2009US20090048429 aspartic acid aldehyde moieties via reduction, deprotecting, reacting with benzyloxycarbonyl-tert-leucine under coupling conditions, deprotection conditions to provide amine and reacting amine and 4-amino-3-chlorobenzoic; for preparing caspase inhibitors and/or prodrugs
02/19/2009US20090047687 Indane Acetic Acid Derivatives and Their Use as Pharmaceutical Agents, Intermediates, and Method of Preparation
02/11/2009CN101363191A Method for preparing chiral recognition functional fiber
02/11/2009CN101362696A New preparation method of 3-aminomethyl-5-methyl butylacetic acic
02/05/2009WO2009016251A1 Process for the resolution of zopiclone and intermediate compounds
02/05/2009CA2695254A1 Process for the resolution of zopiclone and intermediate compounds
02/04/2009EP2020403A1 Process for the resolution of zopiclone and intermediate compounds
02/04/2009CN101357925A Pentaerythritols chiral spiro compound and synthesis and resolution method thereof
02/04/2009CN100457746C Method for the preparation of escitalopram
01/2009
01/29/2009US20090030210 Process for Producing Optically Active 2-Alkylcysteine, Derivative Thereof, and Processes for Production
01/22/2009US20090023931 Alanine racemase chiral binaphthol derivative with powerful hydrogen bond donor, and optical resolution and optical transformation methods using the same
01/21/2009EP2017244A2 Chiral binaphtol derivatives as alanine racemase mimics with powerful hydrogen bond donors: their use for optical resolution and optical inversion
01/21/2009CN101351447A Organic compounds and manufacture thereof
01/21/2009CN100453542C Resolution method for 2-hetero ring substituted dihydropyrimidine racemic compounds
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