Patents
Patents for C07B 57 - Separation of optically-active organic compounds (3,737)
12/1999
12/23/1999WO1996002535A8 Process for synthesis of substituted sulphoxides
12/22/1999EP0965588A1 Process for the preparation of 4-phenyl-1,2,3,6-tetrahydropyridine derivatives and intermediates used in this process
12/08/1999CN1237959A Process for preparation of an inorganic salt of an optically active
12/08/1999CN1047167C Process for enantioselective synthesis used as intermediates in preparation of physostigmine
11/1999
11/30/1999US5994560 Utilizes polymers containing chiral moieties in their repeat units as well as exhibiting critical solution temperature behavior in a suitable solvent. resolution of tryptophan, phenylalanine or glutamic acid.
11/30/1999US5994548 Crystallisation of levibupivacaine and analogues thereof
11/18/1999WO1999058532A1 Method for producing (s,s)-benzyl-2,8-diazabicyclo[4.3.0]nonane
11/18/1999DE19821039A1 Production of (S,S)-8-benzyl-2,8-diazabicyclo(4.3.0)nonane useful as intermediate for antibiotic moxifloxacin
11/16/1999CA2004887C Recovery of l-amino acid isomers from their racemic mixtures
11/11/1999WO1999057089A1 Process for the production of enantiomerically pure or optically enriched sertraline-tetralone using continuous chromatography
11/11/1999WO1999056699A2 Main-group metal-based asymmetric catalysts and applications thereof
11/11/1999CA2329316A1 Main-group metal-based asymmetric catalysts and applications thereof
11/09/1999US5981807 Production of optically active 2-halo-1-(substituted phenyl)ethanol and substituted styrene oxide
11/02/1999US5977409 Method of using α-substituted benzylamine chiral auxiliary synthetic reagents
10/1999
10/26/1999US5973151 Aromatic condensation compounds useful as optically active building blocks
10/21/1999WO1999052886A1 Kinetic resolution of olefins
10/21/1999CA2328299A1 Kinetic resolution of olefins
10/14/1999WO1999042192A8 Packed capillaries, especially for enantiomeric separation
10/12/1999US5964996 Electrophoresis of fluid containing the enantiomers with a macrocyclic antibiotic, which causes sequential separation of enantiomers by complexation, inclusion, hydrogen bonding, dipole stacking or steric interaction
10/06/1999EP0946496A2 Process for resolving mixtures of carbocyclic stereoisomers
10/06/1999EP0946467A1 Method for splitting 1-amino-alkan-2-ol compounds
09/1999
09/29/1999EP0664784B2 Enantiomeric resolution
09/28/1999US5959161 Method for producing para-menthane-3,8-diol
09/28/1999US5959112 Solvent extraction to liberate hydrochloric acid salt with dilute base, pipecoloxylidide is resolved by crystallization with water, alkylating with 1-halopropane in presence of catalyst, heating and removing inorganic salt by extraction
09/28/1999US5959050 Comprising spherical, uniformly shaped, and non-aggregated particles formed by suspension polymerization of two distinct acrylic monomers in the presence of imprint molecule, liquid flurocarbon, fluorocarbon polymer
09/23/1999WO1999047475A1 Method for separating a diphosphine diastereoisomers
09/23/1999WO1999047228A1 Improved method for enriching optical isomers by means of simulated mobile bed
09/23/1999CA2322986A1 Method for separating a diphosphine diastereoisomers
09/15/1999EP0752980B1 Substituted phenyl compounds and processes for preparing the same
09/15/1999CN1228423A Process for preparation of optically active indoline-2-carboxylic acid or derivative thereof
09/14/1999US5952503 Method for producing optically-active 2-piperazinecarboxylic acid derivatives
09/07/1999US5948904 Process for the preparation of aromatic carbamoyl-substituted polysaccharide derivatives
09/07/1999US5948789 Process for synthesis of substituted sulphoxides
09/02/1999WO1999043668A1 NOVEL β-DIKETONE COMPOUNDS, β-DIKETONE COMPOUNDS COORDINATED TO METAL, METHOD OF ORGANIC SYNTHESIS WITH THESE, AND CATALYST
09/01/1999CN1227210A Liquid phase chromatography device and method for separating optical isomeric compound
08/1999
08/26/1999WO1999042192A1 Packed capillaries, especially for enantiomeric separation
08/26/1999DE19807063A1 Production of capillaries with a chiral sorbent bed
08/25/1999EP0937714A1 Process for the preparation of an optically active indoline-2-carboxylic acid or derivative thereof
08/25/1999EP0937056A1 A process for the preparation of (-)-3,4-trans-diarylchromans
08/17/1999US5939409 Processes for the production of anti-inflammatory steroids
08/10/1999US5936118 Process for chiral enrichment of optically active carboxylic acids or salts or esters thereof
08/05/1999WO1999038594A1 Separation of substance mixtures using polysaccharides
08/05/1999DE19803415A1 Trennung von Stoffgemischen unter Einsatz von Polysacchariden Separation of mixtures of substances using polysaccharides
08/05/1999CA2319386A1 Separation of substance mixtures using polysaccharides
08/04/1999EP0933360A1 Synthesis of new beta-lactams
07/1999
07/28/1999CN1224019A Process for manufacture of bis (phosphine oxide)- and bis (phosphonate) -compounds
07/28/1999CN1044367C (S)-alpha-phenyl-2-pyridine-ethylamine, its preparing method and composition contg. same
07/27/1999US5929232 Stereoselective ring opening reactions
06/1999
06/30/1999EP0926152A1 Process for the manufacture of bis(phosphine oxide)-and bis(phosphonate)-compounds
06/30/1999EP0926131A2 Process for the preparation of aminoalcohol derivatives and their further transformation zu (1R,4S)-4-((2-amino-6-chlor-5-formamido-4-pyrimidinyl)-amino)-2-cyclopenten-1-methanol
06/30/1999CN1221418A Preparation of (7S, trans)-2-(2-pyrimidinyl)-7-(hydroxymethyl) octahydro-2h-pyrido [1,2-A] pyrazine
06/30/1999CN1221413A Enantiomer separation from dioxide pyranium ester
06/23/1999CN1220664A Process for producing phenoxy propionic acid derivatives
06/22/1999CA2256865A1 Synthesis of new .beta.-lactams
06/16/1999CN1043645C New benzothiadiazine compound, process for its preparation and pharmaceutical compositions which contain it
06/09/1999CN1218795A Process for preparation of aminoalcohol derivatives and their further conversion to (1R,4S)-4-((2-amino-6-chloro-5-formamido-4-pyrimidinyl) amino)-2-cyclopentenyl-1-methanol
06/02/1999EP0918744A1 Racemic separation of ketamine
05/1999
05/27/1999CA2591571A1 Process for the preparation of aminoalcohol derivatives and their further conversion to (1s,4r)- or (1r,4s)-1-amino-4-(hydroxymethyl)-2-cyclopentene
05/19/1999EP0915849A2 Process for the preparation of 3,3-disubstituted piperidines
05/19/1999EP0813574B1 Process for the preparation of aromatic carbamoyl-substituted polysaccharide derivatives
05/19/1999CN1216972A Improved process for prodn. of enantiomerically-pure azetidine-2-carboxylic acid
05/12/1999EP0915335A1 A separating agent comprising an optically active polymer and polystyrene cristalline deposited on a carrier
05/06/1999WO1999021811A1 Method of separating optical isomers
05/06/1999EP0912569A1 Preparation of (7s,trans)-2-(2-pyrimidinyl)-7-(hydroxymethyl)octahydro-2h-pyrido 1,2-a]pyrazine
05/06/1999EP0912528A1 Processes for producing phenoxy propionic acid derivatives
05/04/1999US5900144 Separating agent comprising bonded conalbumin
04/1999
04/15/1999WO1999018052A1 Separating agent for optical isomers and process for producing the same
04/14/1999EP0907663A1 Thermally immobilized polysaccharide derivatives
04/07/1999EP0906906A1 Process for preparing optically active 2-piperazinecarboxylic acid derivatives
04/07/1999EP0906900A1 A process for preparing optically active 2-hydroxy-methyl-3-phenylpropionic acid
04/07/1999EP0906302A1 Enantiomer separation from chromane acid esters
04/07/1999EP0906255A1 Improved process for the production of enantiomerically-pure azetidine-2-carboxylic acid
04/07/1999EP0804405B1 Process for producing optically active 2-halogen propionic acids
04/07/1999EP0570454B1 Novel steroids
04/06/1999US5892098 Inhibit activity of phosphodiesterase iv and production of tumor necrosis factor; treating asthma
03/1999
03/30/1999US5889186 Resolution using fluidized bed chromatography
03/30/1999US5889180 Separation; resolution; adsorption
03/23/1999US5886214 Catalytic asymmetric hydrogenation of enol esters bearing a vinyllic or an acetylenic substituent by using a chiral rhodium(i) hydrogenation catalyst prepared from a suitable rhodium salt and an optically pure phosphine ligand
03/23/1999CA2022611C Optical resolution method for 3s-(3-carboxybenzyl)-6-(5-fluoro-2-benzothiazolyl)methoxy-4s-chromanol
03/17/1999EP0736045B1 Use of mono-3,6-anhydro-cyclodextrins for solubilising a hydrophobic compound and monitoring the purity of an enantiomer, and method for preparing said cyclodextrins
03/10/1999CN1042418C Optical isomer separating agent and process for prodcuing the same and its use
03/04/1999WO1998054228A3 Amide containing molecular imprinted polymers
03/03/1999EP0899272A1 Mono and di-derivatives of cyclodextrins, their synthesis and purification and their use as carrier
03/03/1999EP0612322B1 Method of separating the enantiomers of 5-methyl-tetrahydrofolic acid
02/1999
02/28/1999CA2243640A1 Mono and di-derivatives of cyclodextrins, their synthesis and purification and their use as support
02/23/1999US5874005 Separation of enantiomorphs in solution; chromatography, electrophoresis
02/16/1999US5872198 Molecularly imprinted polymer supports capable of separating or resolving amino-acids, amino-acid derivatives, pharmaceutical compounds and polysaccharides
02/09/1999USRE36092 Cyclodextrins which have been alkylated or alkenylated, optionally acylated
02/09/1999US5869668 Processes for preparing L!- or D!-homoalanin-4-yl-(methyl) phosphinic acid and salts thereof by racemate resolution
02/09/1999US5868938 Chromatographic supports
02/03/1999EP0894087A2 Method for obtaining pure enantiomers of a pyridazinone derivative
02/03/1999EP0748325B1 Process for preparing [l]- or [d]-homoalanin-4-yl-(methyl)phosphinic acid and its salts by racemic resolution
02/03/1999EP0632794B1 Method for separating enantiomers of aryloxipropanolamine derivatives, and chiral solid-phase chromatography material for use in the method
01/1999
01/27/1999EP0893453A2 Chiral separation of pharmaceutical compounds with charged cyclodextrins using capillary electrophoresis
01/07/1999EP0888367A1 Isolated rna molecules which bind to arginine and uses thereof
01/05/1999US5856579 Adduct salts of novel substituted benzylamines and a process for optically resolving them
12/1998
12/24/1998DE19717429A1 Herstellung enantiomerenreiner Biarylketocarbonsäuren Preparation of enantiomerically pure Biarylketocarbonsäuren
12/23/1998EP0720595B1 Method of resolution of two enantiomers by crystallization
12/22/1998US5852209 Process for optically resolving 2-(3-benzoylphenyl) propionic acid
12/15/1998US5849961 Optically active 1,1'-biphenanthryl-2,2'-diol, process for preparing the same, and resolving reagent comprising the same
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