Patents
Patents for C07B 57 - Separation of optically-active organic compounds (3,737)
09/2000
09/06/2000CN1056145C Prepn. of 1,3-oxathiolane nucleoside analogue medicine composition
08/2000
08/31/2000WO2000050378A2 Synthesis of nitroalcohol diastereomers
08/31/2000CA2364266A1 Synthesis of nitroalcohol diastereomers
08/30/2000EP1031575A1 Process for preparing growth hormone secretagogues
08/30/2000EP0828702B1 Process for resolving chiral acids with 1-aminoindan-2-ols
08/30/2000EP0763010B1 Enantioselective preparation of optically pure albuterol
08/30/2000CN1055911C Process for preparing high antimer pure (R) -(+)-and (S)-(-)-1, 1-bi-2-naphthol
08/29/2000CA2184104C Production of optically active 2-halo-1-(substituted phenyl)ethanol and substituted styrene oxide
08/24/2000WO2000048987A1 Novel substituted 3-phenoxy and 3-phenylalkyloxy-2-phenyl-propylamines
08/24/2000DE19907385A1 New 3-(phenoxy or phenylalkoxy)-2-phenyl-propylamines, useful for treating e.g. arrhythmia, spasms, pain or neurodegenerative diseases, are tension-dependent sodium channel blockers
08/22/2000CA2042421C A method for the preparation in a non-racemic form of furo (3,4-c) pyridine derivatives
08/17/2000WO2000047546A1 Method for the racemization of optically active amines
08/17/2000WO2000047545A1 Method for the racemization of optically active amines
08/17/2000DE19905838A1 Verfahren zur Racemisierung von optisch aktiven Aminen A process for the racemization of optically active amines
08/17/2000DE19905837A1 Verfahren zur Racemisierung von optisch aktiven Aminen A process for the racemization of optically active amines
08/16/2000EP0584108B1 Pharmaceutical composition comprising ibuprofen salt
08/09/2000EP1026135A1 Production of optically active 2-halo-1-(substituted phenyl)-ethanol and substituted styrene oxide
07/2000
07/26/2000EP0738284B1 Polysaccharide derivatives and their use for preparing stationary chiral phases suitable for separating isomers
07/25/2000US6093846 Process for preparing optically active 2-hydroxy-methyl-3-phenylpropionic acid
07/25/2000US6093823 By continuous racemate splitting via diastereomeric salt pairs with re-racemisation of the residual amino acid or amino acid derivative in the mother liquid with the aid of an optically active acid
07/19/2000EP1019363A1 Process for the preparation of an inorganic salt of an optically active phenylglycine derivative
07/19/2000CN1054605C Method for preparing optically active 2-tetrahydrofuran formic acid
07/19/2000CN1054603C Tri-substituted phenyl derivatives and medicinal composition containing same
07/18/2000US6090250 Chiral surfactants and methods for their use in chiral separations
07/13/2000WO2000040539A1 Use of substituted 4-biarylbutyric and 5-biarylpentanoic acid derivatives as matrix metalloprotease inhibitors for the treatment of respiratory diseases
07/13/2000CA2356053A1 Use of substituted 4-biarylbutyric and 5-biarylpentanoic acid derivatives as matrix metalloprotease inhibitors for the treatment of respiratory diseases
07/05/2000EP0759904B1 Process and diastereomeric salts useful for the optical resolution of racemic 4-[4-[-4-(hydroxydiphenylmethyl)-1-piperidinyl]-1-hydroxybutyl]-alpha,alpha-dimethylbenzene acetic acid.
06/2000
06/28/2000CN1053902C Hydrogenation process
06/21/2000CN1053669C Processfor preparing [L]- or [D]-homoalamin-4 YL-(methyl phosphinic acid and its salts by racemic resolution
06/21/2000CN1053655C Process for the preparation of an optically pure aminoalcohol
06/08/2000WO2000032638A1 Polysaccharide chiral esters, one of the methods for preparing them and their uses for obtaining optically enriched acids or chiral chromatography
06/08/2000WO2000032556A1 Derivatives of (-)-venlafaxine and methods of preparing and using the same
06/08/2000WO2000032555A1 Derivatives of (+)-venlafaxine and methods of preparing and using the same
06/08/2000WO2000032554A1 Process for the resolution of tramadol
06/08/2000CA2353702A1 Polysaccharide chiral esters, one of the methods for preparing them and their uses for obtaining optically enriched acids or chiral chromatography
06/08/2000CA2353549A1 Process for the resolution of tramadol
06/08/2000CA2352321A1 Derivatives of (+)-venlafaxine and methods of preparing and using the same
05/2000
05/18/2000WO2000027778A1 Resolution method for a racemic mixture of aldehydes
05/18/2000WO1999056699A3 Main-group metal-based asymmetric catalysts and applications thereof
05/18/2000CA2349918A1 Resolution method for a racemic mixture of aldehydes
05/17/2000CN1253539A Production of enantiomer-free biarylketocarboxylic acids
05/11/2000WO2000026170A1 Method for racemate splitting of 2-hydroxypropionic acids
05/11/2000WO2000025885A1 Separation method and device with chromatographic zones with variable length
05/10/2000CN1052155C Process for preparing pharmaceutical composition containing new steriod compounds
05/04/2000WO2000024711A1 Synthesis of methylthiophenyl hydroxyketones
05/04/2000DE19850301A1 Verfahren zur Racematspaltung von 2-Hydroxypropionsäuren A method for resolution of 2-hydroxypropionic
05/04/2000CA2347768A1 Synthesis of methylthiophenyl hydroxyketones
04/2000
04/27/2000WO2000023414A2 Synthesis of optically active cyclohexylphenylglycolic acid and its esters
04/27/2000CA2347736A1 Synthesis of optically active cyclohexylphenylglycolic acid and its esters
04/11/2000US6049007 Racemization of optically active amines
04/06/2000WO2000018724A1 (R)-CHIRAL HALOGENATED 1-SUBSTITUTEDAMINO-(n+1)-ALKANOLS USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY
04/06/2000WO2000018721A1 Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity
04/05/2000EP0808302B1 2-aryl-2-alkyl-omega-alkylaminoalkane nitrile racemate separation process
04/05/2000EP0805793B1 Preparation of optically active aliphatic carboxylic acids
04/04/2000US6046353 Method of making (S)-3-(aminomethyl)-5-methylhexanoic acid
03/2000
03/30/2000WO2000017153A1 METHOD FOR PRODUCING (-)-α-(DIFLUOROMETHYL)ORNITHINE-MONOHYDROCHLORIDE MONOHYDRATE
03/30/2000WO2000017133A2 Lta4 hydrolase inhibitors
03/30/2000CA2345112A1 Process for the preparation of (-)-a-difluoromethylornithine monohydrochloride monohydrate
03/29/2000EP0988544A2 Amide containing molecular imprinted polymers
03/28/2000US6043359 Processes for the preparation of derivatives of 4a,5,9,10,11,12-hexahydro-6H-benzofuro-[3a,3,2-ef][2]benzazepine
03/28/2000US6042723 Mono- and di-derivatives of cyclodextrins, synthesis thereof and purification and use thereof in a support
03/21/2000US6040479 Reacting racemic ketamine with an enantiomeric form of tartaric acid; isolating the salt formed; reacting the salt with an alkali to isolate an isomer; using water or a mixture of water and an alcohol and/or ketone, ether or ester
03/15/2000EP0985682A1 Polysaccharides and oligosaccharides crosslinked with bissilane-, bisthioether-, bissulphoxyde-, bissulphone- and butanediyl-derivatives and their shaping as substrate materials
03/15/2000EP0985681A1 Chloro-, hydroxy- and alcoxysilanes derivatives of polysaccharides or oligosaccharides, polymerizables and crosslinkables, process for their preparation and their use as substrate materials
03/02/2000WO2000010968A2 Novel aryl sulphonamide amino acid esters and analogues
03/02/2000CA2341028A1 Novel aryl sulphonamide amino acid esters and analogues
03/01/2000CN1245800A Method for preparing substituted piperidine
03/01/2000CN1049883C Separating agent for optical isomers
02/2000
02/24/2000WO2000009493A1 Enantioselective synthesis
02/24/2000WO2000009463A1 Stereoselective ring opening reactions
02/24/2000DE19837627A1 New aminoacid esters of arylsulfonamides are useful for e.g. treating neurodegenerative diseases, pain, convulsions or bacterial or viral infections
02/24/2000CA2339618A1 Stereoselective ring opening reactions
02/23/2000EP0980860A1 Optically active secondary alcohol and process for the production thereof
02/22/2000US6028217 Chemical intermediate for renin inhibitor or enkephalinase enzyme inhibitor
02/22/2000US6027648 A separating agent comprising a stationary phase in which ovomucoid part of which has been modified and a carrier on which the modified ovomucoid has been immobilized, contacting the separating agent with the mixture of optical isomers
02/16/2000EP0979819A1 Process for the production of substituted 3-hydroxypiperidines
02/15/2000US6025531 Processes for preparing optically active alcohols and optically active amines
02/09/2000EP0978498A1 Separating agent for optical isomers and process for producing the same
02/09/2000EP0977724A1 Process for chiral enrichment of optically active carboxylic acids, or salts or esters thereof
02/09/2000EP0977717A1 Production of enantiomer-free biarylketocarboxylic acids
02/08/2000US6022409 Method of resolution of two enantiomers by crystallization
02/03/2000WO2000005196A1 α-AMINO ACID PHENYL ESTER DERIVATIVES
02/03/2000CA2337945A1 .alpha.-amino acid phenyl ester derivatives
01/2000
01/26/2000EP0973705A1 Chromatographic enantiomer separation of lactones
01/26/2000CN1242358A Process for prepn. of optically pure aminoalcohol
01/20/2000WO2000002834A1 Asymmetric metathesis reactions involving achiral and meso substrates
01/19/2000EP0840752B1 Photochemically cross-linked polysaccharide derivatives having no photopolymerisable functional groups
01/18/2000US6015903 Method of resolving racemic mixtures
01/13/2000WO2000001689A1 Process for producing (8- chloro-3,10- dibromo-6,11- dihydro- 5h-benzo [5,6]cyclohepta [1,2-b]pyridin-11-yl)- 1-piperidine
01/13/2000WO2000001642A1 Chiral recognition polymer and its use to separate enantiomers
01/13/2000CA2335967A1 Process for producing (8- chloro-3,10- dibromo-6,11- dihydro- 5h-benzo ¬5,6|cyclohepta ¬1,2-b|pyridin-11-yl)- 1-piperidine
01/12/2000EP0970936A1 A method for resolving optical isomers
01/12/2000EP0970935A1 Method of separating optical isomers
01/12/2000CN1241173A Separating agent for optical isomers and process for producing same
01/12/2000CN1241172A Method of separating optical isomers
01/06/2000WO2000000464A1 Chiral stationary phases for enantiomers separation and their preparation
01/06/2000CA2336105A1 Chiral stationary phases for enantiomers separation and their preparation
01/06/2000CA2276901A1 A method for resolving optical isomers
01/05/2000EP0787115B1 PROCESS FOR PRODUCING DERIVATIVES OF 4a,5,9,10,11,12,-HEXAHYDRO-6H-BENZOFURO[3a,3,2-ef][2]BENZAZEPINE
01/04/2000US6011149 Esterification; carbamylation
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