Patents
Patents for C07B 57 - Separation of optically-active organic compounds (3,737)
04/1996
04/25/1996CA2202911A1 Process for separating enantiomers from a racemic mixture
04/23/1996US5510530 Optically active sulphur-containing amino acid derivatives
04/23/1996US5510520 Reacting optically active bifunctional resolving agent with bifunctional compound to form liquid material, precipitating crystals, separating, treating with acid and/or base, heating liquid, cooling, separating crystals, treating as before
04/23/1996US5510519 Optically active secondary amine compound, process for producing optically active secondary amine compound and process for producing optically active carboxylic acid by using said compound
04/17/1996EP0706982A1 Method of separating optical isomers
04/03/1996EP0703903A1 Enantiomers of 4-(5-fluoro-2,3-dihydro-1h-inden-2-yl)-1h-imidazole
03/1996
03/28/1996WO1996009290A1 Racemisation and asymmetric transformation processes used in the manufacture of levobupivacaine and analogues thereof
03/27/1996EP0703229A2 Process for the preparation of (R)-3-amino-5-methoxychroman
03/27/1996EP0703212A1 Process for optically resolving 2-(3-benzoylphenyl) propionic acid
03/27/1996CA2145822A1 Process for optically resolving 2-(3-benzoylphenyl) propionic acid
03/26/1996US5502199 Process for preparing sodium 3R,5S-(+)-erythro-(E)-7- 4-(4-fluorophenyl)-2,6-diisopropyl-5-methoxymethyl-pyrid-3-yl!-3,5-dihydroxy-hept-6-enoate
03/13/1996EP0700381A1 Process for the enantioselective synthesis of intermediates used in the preparation of physostigmine
03/13/1996EP0516686B1 Separation by carrier mediated transport
03/12/1996US5498752 Process for recovering optical isomers and solvent, process for using solvent by circulation and process for reusing optical isomers in optical resolution
03/06/1996EP0530336B1 Chiral phosphines
03/05/1996US5496937 Polysaccharide substances, process for producing them and use of them
02/1996
02/27/1996US5495012 Process for preparing optically active 4-mercapto-2-pyrrolidone derivative and intermediate therefor
02/27/1996US5494915 Isoindolinone derivative, preparation thereof, and pharmaceutical compositions containing same
02/21/1996EP0697404A1 New enantiomerically pure pyridyl cycloalkylethyl amines and their salts as well as process for their production
02/14/1996EP0532664B1 Supported chiral liquid membrane for the separation of enantiomers
02/13/1996US5491260 Acylating carnitine nitrile or amide, hydrolyzing under acid conditions, lactonizing by treating with base, converting to carnitine by treating with base
02/13/1996US5491223 Polysaccharide derivative and separating agent
02/07/1996EP0672029A4 SELECTIVE PRECIPITATION OF -g(a)-ARYL CARBOXYLIC ACID SALTS.
02/06/1996US5489684 Acidification of the racemic alkali salt mixture with a non-oxidizing acid while stereospecific crystallization
02/06/1996CA1338034C Process for the optical resolution of a racemic acid
02/01/1996WO1996002535A1 Process for synthesis of substituted sulphoxides
01/1996
01/30/1996US5488172 Chiral phosphorus compounds
01/25/1996WO1996001995A1 Separating agent
01/17/1996EP0692484A1 Benzothiadiazine derivative process for its preparation and pharmaceutical compositions containing it
01/16/1996US5484530 Separation of enantiomers of non-steroidal anti-inflammatory drugs and chiral selector therefor
01/02/1996US5481026 Addition polymerizable to chromatographic supports for separation of racemic mixtures
01/02/1996US5481008 Process for the preparation of optically active compounds
12/1995
12/27/1995EP0688760A1 Addition salts of acyl-amino acids and alpha-aryl-amines and process for the optical resolution of alpha-arylamines
12/26/1995US5478958 Methyldioxolan
12/26/1995US5478954 Recrystallizing mixture of two enantiomers in an organic solvent mixture comprising aliphatic and aromatic hydrocarbons, halogenated aliphatic and aromatic hydrocarbons, ethers. esters, and amides
12/22/1995CA2148172A1 Addition salt of acyl-amino acid and .alpha.-aryl amine and process for optical resolution of .alpha.-arylamine
12/20/1995EP0687264A1 Method for preparing n-methyl 2-(3-pyridyl) (1r,2r)-2-tetrahydrothiopyrancarbothioamide-1-oxide
12/14/1995WO1995033749A1 A process for the preparation and separation of diastereomeric salts of folinic acid
12/05/1995US5473075 Diastereomer salt of optically active quinolinemevalonic acid
12/05/1995US5472599 Optical resolution of isomers
11/1995
11/30/1995WO1995032178A1 Enantioselective preparation of optically pure albuterol
11/29/1995EP0570443B1 Aminoalcohols useful as optical resolving agents
11/28/1995CA1337659C Optical isomers of an imidazole derivative
11/23/1995WO1995031436A1 PROCESS AND DIASTEREOMERIC SALTS USEFUL FOR THE OPTICAL RESOLUTION OF RACEMIC α-[4-(1,1-DIMETHYLETHYL)PHENYL]-4-(HYDROXYDIPHENYLMETHYL)-1-PIPERIDINEBUTANOL AND DERIVATIVE COMPOUNDS
11/23/1995WO1995031420A1 Separating agent for optical isomers
11/15/1995EP0682267A1 Nmr chiral shift reagent comprising sugar derivative
11/02/1995WO1995029142A1 Method of separating optical isomers
11/01/1995CN1111057A Optical isomer separating agent and process for producing the same
11/01/1995CN1030195C Hypoglycemic thiazolidinediones and intermediates
10/1995
10/25/1995EP0598765B1 2-aminonaphthyridine derivative, its preparation and use
10/24/1995US5461175 Method for separating enantiomers of aryloxipropanolamine derivatives, and chiral solid-phase chromatography material for use in the method
10/18/1995CN1030079C Process for preparation of (6S)-and (6R)-tetrahydrofolic acid
10/12/1995WO1995026950A1 Substituted phenyl compounds and processes for preparing the same
10/10/1995US5457224 Separating the racemic mixture by reacting with optical active dibenzoyltartaric acid or ditoluoyltartaric acid in a water mixture of methanol or acetone and inorganic acid, crystallization
10/10/1995US5457212 Resolution of a thienopyran derivative using methylbenzyl isocyanate; nitration
10/10/1995US5457202 Adding N-ethyl-2-aminomethylpyrrolidine to a racemic mixture to form a precipitating salt; heating to dissolve one stereoisomer
10/10/1995US5456825 Simulated moving bed separation system
09/1995
09/20/1995EP0672030A1 Process for preparing substantially pure enantiomers of phenylpropionic acids.
09/20/1995EP0672029A1 SELECTIVE PRECIPITATION OF $g(a)-ARYL CARBOXYLIC ACID SALTS
09/20/1995EP0671975A1 Chiral adsorbents and preparation thereof as well as compounds on which the adsorbents are based and preparation of these compounds
09/20/1995CN1108655A 1,3-oxathiolane nucleoside analogues
09/12/1995US5449778 Peptide intermediates
09/12/1995US5449728 Optically active acetylene polymer, membrane thereof and optical resolution method using the same
09/08/1995WO1995023805A1 Process for preparing [l]- or [d]-homoalanin-4-yl-(methyl)phosphinic acid and its salts by racemic resolution
09/08/1995CA2184718A1 Process for preparing [l]- or [d]-homoalanin-4-yl-(methyl)phosphinic acid and its salts by racemic resolution
09/07/1995DE4407197A1 Verfahren zur Herstellung von /L/-Homoalanin-4-yl-(methyl)phosphinsäure und deren Salze durch Racematspaltung A process for preparing / L / -homoalanin-4-yl (methyl) phosphinic acid and salts thereof by racemate resolution
09/06/1995EP0625153B1 Isoindolinone derivative, preparation thereof, and pharmaceutical compositions containing same
09/06/1995EP0478721B1 New benzocycloalkene carboxylic acid and process for producing it
08/1995
08/30/1995EP0668861A1 Process for preparing enantiomerically pure 6- (4-chlorophenyl)(1h --triazol-1,2,4-triazol-1-yl)methyl]-1-methyl-1h --benzotriazole
08/29/1995US5445963 Alcohol-ester separation by recrystallization
08/24/1995WO1995022521A1 Aminoalkylcyclopropane derivative
08/24/1995WO1995022390A1 Macrocyclic antibiotics as separation agents
08/23/1995EP0667852A1 Novel 3,3-diphenylpropylamines, their use and preparation
08/09/1995EP0363428B1 Conversion of pyrethroid isomers to more active species
08/08/1995US5439979 Separating materials
08/03/1995WO1995020590A1 Enantioselective receptors for amino acid derivatives, and other compounds
08/02/1995EP0664784A1 Enantiomeric resolution.
08/02/1995EP0664783A1 Enantiomeric resolution
08/02/1995EP0664782A1 Enantiomeric resolution
08/02/1995EP0664781A1 Enantiomeric resolution
08/02/1995CN1106002A Hydrogenation process
07/1995
07/26/1995EP0663897A1 Process for separating enantiomers from a racemic mixture.
07/25/1995US5435919 Optically-active, amhiphilic, water-soluble free-radical addition copolymers and their use in the resolution of racemic mixtures
07/18/1995US5434299 Process for recovering optical isomers and solvent, process for using solvent by circulation and process for reusing optical isomers in optical resolution
07/18/1995US5434298 Process for recovering optical isomers and solvent, process for using solvent by circulation and process for reusing optical isomers in optical resolution
07/13/1995WO1995018833A1 Polysaccharide derivatives and their use for preparing stationary chiral phases suitable for separating isomers
07/11/1995US5432252 Acrylamide derivatives; use as polymeric adsorbent in separation of racemic mixtures into their optical antipodes
07/11/1995US5432251 Acrylamide derivatives; use as polymeric adsorbent in separation of racemic mixtures into their optical antipodes
06/1995
06/29/1995WO1995017433A1 Use of mono-3,6-anhydro-cyclodextrins for solubilising a hydrophobic compound and monitoring the purity of an enantiomer, and method for preparing said cyclodextrins
06/28/1995EP0659172A1 Analogues of vpa used as anti-epileptica.
06/21/1995EP0658550A2 Amino acid salts of and methods for preparing antihypercholesterolemic tetrazole compounds
06/16/1995CA2137049A1 Amino acid salts of and methods for preparing antihypercholesterolemic tetrazole compounds
06/15/1995WO1995015953A1 Novel substituted oxazolidines
06/13/1995US5424446 Process for preparing optically active 4-mercapto-2-pyrrolidone derivative and intermediate therefor
06/13/1995US5424428 (-)-[[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]-hydrazono]pr
06/07/1995EP0656333A1 Optical isomer separating agent and process for producing the same
06/06/1995US5422417 Substituted phenyl compounds and processes for preparing the same
06/06/1995US5422004 Monocyclic or polycyclic aromatic amide moiety; increased enantioselectivity
06/01/1995WO1995014934A1 Nmr chiral shift reagent comprising sugar derivative
05/1995
05/30/1995US5420319 Cis-oxalato(trans-1-1,2-cyclohexanediamine) Pt(II) complex having high optical purity and process of preparing same
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