Patents
Patents for C07B 57 - Separation of optically-active organic compounds (3,737)
01/2002
01/17/2002US20020006960 Neuraminidase inhibitors
01/16/2002EP1171417A1 Methods for preparing 3-aryloxy-3-arylpropylamines and intermediates thereof
01/08/2002US6337328 Bupropion metabolites and methods of use
01/03/2002WO2002000601A1 Process for producing 3-amino-2-hydroxypropionic acid derivatives
01/03/2002US20020002283 Process for preparing growth hormone secretagogues
01/02/2002CN1329587A Process for resolution of tramadol
12/2001
12/27/2001WO2001098370A1 Materials comprising oligo- or polysaccharide cross linked and chemically bonded to a support via urea linkages useful for chromatography and electrophoresis applications
12/27/2001WO2001098265A2 Process for isolating enantiomers of racemic cetamine
12/25/2001US6333426 Chiral adsorbents and preparation thereof as well as compounds on which the absorbents are based and preparation of the compounds
12/19/2001EP1163200A1 Method of industrial-scale purification of lactic acid
12/19/2001CN1326922A Process for preparing optic pure 2-fluoro-alphar-methyl-[1,1'-diphenyl]-4-acetic acid
12/19/2001CN1326743A Process for preparing 1,3-oxygen-sulphur cyclopentane nucleotide like medicine composition
12/13/2001WO2001094333A2 Process for the preparation of benzoyl substituted bicyclic compounds and chiral benzopyran derivatives
12/13/2001WO2000023414A3 Synthesis of optically active cyclohexylphenylglycolic acid and its esters
12/13/2001US20010051747 Diastereomer complex of at least three compounds, at least one is a resolving agent in optically active form, and at least one is an enantiomer in optically active form; rapid separation
12/12/2001EP0830338B1 Method of making 3-(aminomethyl)-5-methylhexanoic acid
12/11/2001US6329408 Hypocholesterolemic agents; optically pure
12/05/2001EP1159253A2 Synthesis of nitroalcohol diastereomers
12/05/2001EP1159252A1 Method for the racemization of optically active amines
12/05/2001CN1325375A Method for racemate splitting of 2-hydroxypropionic acids
12/04/2001CA2000553C Process for the preparation of 7-substituted-hept-6-enoic and -heptanoic acids and derivatives and intermediates thereof
11/2001
11/28/2001EP1156864A1 Co-crystallization process
11/27/2001US6323368 Resolving racemic tramadol by classical salt resolution using a substantially single enantiomer of o,o-di-p-toluoyltartaric acid as a resolving agent
11/22/2001WO2001032691A8 Hcv ns3 protease inhibitors
11/22/2001WO2001019761A3 Asymmetric 1,4-reductions of and 1,4-additions to enoates and related systems
11/22/2001US20010044471 Hydrogenation of racemic 6-alkoxy-1H-indene-1,2(3H)-dione-2-oxime, with chiral acid, resolution, alkylation, bromination, carboxamidation
11/21/2001EP1154983A1 Novel substituted 3-phenoxy and 3-phenylalkyloxy-2-phenyl-propylamines
11/15/2001WO2001085668A1 Optically active 2-aminotetralin derivatives, the processes for the preparation thereof and the therapeutical use of pharmaceutical compositions containing them
11/15/2001US20010041359 Process for the preparation of optically and chemically highly pure (R) - or (S) -alpha- hydroxycarboxylic acids
11/14/2001EP0763513B1 Production of optically active 2-halo-1-(substituted phenyl)-ethanol and substituted styrene oxide
11/14/2001CN1322200A Enantioselective synthesis
11/14/2001CN1321638A Method for preparing methylsulfonate trihydrate of 1-(4-hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperid-1-yl)-1-propanol
11/13/2001US6316613 Used to separate optical isomers
11/13/2001US6316235 Preparation and use of magnetically susceptible polymer particles
11/08/2001WO2001083422A1 Process for the separation of the cis trans diastereoisomers of tramadol
11/08/2001WO2000017133A3 Lta4 hydrolase inhibitors
11/08/2001EP1144348A3 Lta 4? hydrolase inhibitors
11/07/2001EP1151995A1 Process for the preparation of the mesylate salt trihydrate of 1-(4-Hydroxyphenyl)-2-(4-Hydroxy-4-Phenylpiperidin-1-YL)-1-Propanol
11/07/2001EP1150941A1 Method for the racemization of optically active amines
11/07/2001EP0626939B1 Tri-substituted phenyl derivatives as phosphodiesterase inhibitors
10/2001
10/31/2001EP0828711B1 New process for the preparation of ropivacaine hydrochloride monohydrate
10/25/2001WO2001079174A1 A pyridine-1-oxide derivative, and process for its transformation into pharmaceutically effective compounds
10/24/2001EP1148042A2 Method for producing optically and chemically pure (R)- and (S)-hydroxycarboxylic acids
10/24/2001CN1319085A Method for producing (-)-alpha-(difluoromethyl) ornithine-monohydrochloride monohydrate
10/18/2001US20010031875 Optically active ionic liquid
10/17/2001EP1144348A2 Lta 4? hydrolase inhibitors
10/17/2001CN1073085C Process for prepn. O-desmethyl tramadol antimer
10/17/2001CA2344004A1 Process for the preparation of optically and chemically highly pure (r)- or (s)-a-hydroxycarboxylic acids
10/16/2001US6303796 Chemical intermediates; optically active compounds useful as optical resolution agents; metal-coordinated compounds useful as asymmetric catalysts
10/11/2001US20010029282 Crosslinked support for separation of enantiomorphs
10/10/2001EP1140768A1 Use of substituted 4-biarylbutyric and 5-biarylpentanoic acid derivatives as matrix metalloprotease inhibitors for the treatment of respiratory diseases
09/2001
09/26/2001EP1135417A1 Polysaccharide chiral esters, one of the methods for preparing them and their uses for obtaining optically enriched acids or chiral chromatography
09/26/2001EP1135359A1 Derivatives of (-)-venlafaxine and methods of preparing and using the same
09/26/2001EP1135358A1 Derivatives of (+)-venlafaxine and methods of preparing and using the same
09/26/2001EP1135357A1 Process for the resolution of tramadol
09/26/2001CN1314336A Method for splitting ibuprofen by two-component chiral reagent
09/20/2001WO2001068729A1 Compositions and methods for selectively binding amines or amino acid enantiomers over their counter-enantiomers
09/20/2001WO2001068637A2 Method for the preparation of tetrahydrobenzothiepines
09/20/2001WO2001068566A1 Novel process for preparing (+)-cis-sertraline
09/20/2001CA2402656A1 Process for preparing(+)-cis-sertraline
09/20/2001CA2402241A1 Compositions and methods for selectively binding amines or amino acid enantiomers over their counter-enantiomers
09/19/2001CN1071292C Improved process for prodn. of enantiomericallypure azetidine-2-carboxylic acid
09/13/2001US20010021779 Acetonitrile eluent
09/05/2001EP1128881A1 Separation method and device with chromatographic zones with variable length
09/05/2001CN1311770A Derivatives of alpha-amino acid phenyl ester
09/05/2001CN1070489C Process for synthesis of substituted sulphoxides
08/2001
08/30/2001WO2001062712A1 (2s)-aminoindan derivatives, a process for their preparation and their use as selective dopamine d3 ligands
08/30/2001WO2001062257A2 Bupropion metabolites and methods of their synthesis and use
08/29/2001EP1127872A1 Tamiflu via Diels-Alder
08/29/2001EP1127037A1 Resolution method for a racemic mixture of aldehydes
08/29/2001EP0711742B1 Separating agent for optical isomers
08/29/2001CN1310170A Process for producing 4,5-diamino shikimic acid derivative
08/28/2001US6281391 Reacting hydroxyamide compound with lithiating agent comprising 4-methylthiophenyllithium in non-reacting solvent to form methylthiophenyl-hydroxyketone compound
08/23/2001US20010016665 Condensing isovaleraldehyde with methyldiester compound to form an intermediate, reacting the product with cyanide souce to form cyanide derivative of diesters, decarboxylation and then hydrolysis with a metal hydroxide and hydrogenation
08/22/2001EP1124798A1 Synthesis of methylthiophenyl hydroxyketones
08/22/2001EP1124782A1 Method for racemate splitting of 2-hydroxypropionic acids
08/22/2001CN1309121A Method for resolution of alpha-[4-(1,1-dimethylethyl) phenyl]-4-(hydroxy-diphenylmethyl)-1-piperidyl butanol and its derivs.
08/21/2001US6277782 Chiral adsorbents and preparation thereof as well as compounds on which the adsorbents are based and preparation of these compounds
08/16/2001WO2001058835A1 Resolution of dl-racemic mixtures
08/16/2001WO2001058588A1 Chiral ferrocene phosphines and their use in asymmetric catalytic reactions
08/16/2001CA2400183A1 Chiral ferrocene phosphines and their use in asymmetric catalytic reactions
08/15/2001CN1069630C Process for producing optically active 2-halogen propionic acids
08/15/2001CN1069624C Production of derivatives of 4a,5,9,10,11,12,-bexahydro-6H-benzofuro[3a,3,2-ef][2] benzazepine
08/14/2001US6274736 Chromatographic enantiomer separation of lactones
08/14/2001US6274735 Process and intermediates for preparation of substituted piperidines
08/14/2001US6274686 Amide containing molecular imprinted polymers
08/14/2001CA2150712C Chiral adsorbents and preparation thereof as well as compounds on which the adsorbents are based and preparation of these compounds
08/08/2001EP0906302B1 Enantiomer separation from chromane acid esters
08/02/2001WO2001055095A1 Functional monomers for molecular recognition and catalysis
08/02/2001WO2001055060A2 Chiral ionic liquids
08/02/2001DE10003708A1 Neuartige chirale ionische Flüssigkeiten und Verfahren zu ihrer Darstellung in enantiomerenreiner oder enantiomerenangereicherter Form Novel chiral ionic liquids and methods for their representation in enantiomerically pure or enantiomerically enriched form
07/2001
07/25/2001EP1118623A1 Process for producing chitin derivative
07/25/2001CN1068871C 2-aryl-2-alkyl-W-alkylaminoalkane nitrile recemate separation process
07/24/2001US6265615 Chiral recognition polymer and its use to separate enantiomers
07/19/2001WO2001051453A1 Racemic and optically pure metabolites of sibutramine, their preparation, compositions comprising them and their use as dopamine reuptake inhibitors
07/19/2001CA2396950A1 Racemic and optically pure metabolites of sibutramine, their preparation, compositions comprising them and their use as dopamine reuptake inhibitors
07/18/2001EP1115696A1 Method for producing (-)-alpha-(difluoromethyl)ornithine-monohydrochloride monohydrate
07/18/2001EP1115695A1 (r)-chiral halogenated 1-substitutedamino-(n+1)-alkanols useful for inhibiting cholesteryl ester transfer protein activity
07/18/2001EP1115693A1 SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL $i(TERTIARY)-HETEROALKYLAMINES USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY
07/18/2001EP0721446B1 Chiral surfactants and methods for their use in chiral separations
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