Patents
Patents for C07B 57 - Separation of optically-active organic compounds (3,737)
12/2004
12/23/2004CA2529152A1 Process for the preparation of aromatic amines
12/22/2004CN1181035C Process for preparing optic pure 2-fluoro-alphar-methyl-[1,1'-diphenyl]-4-acetic acid
12/16/2004US20040254380 NK-1 receptor antagonists
12/15/2004CN1555370A Process for the preparation of 5-substituted isobenzofurans
12/08/2004EP1484315A1 Process for production of optically active beta-phenylalanine
12/08/2004EP1484314A1 Process for production of optically active beta-phenylalanine derivatives
12/08/2004EP1412341B1 Process for the preparation of racemic citalopram and/or s- or r-citalopram by separation of a mixture of r- and s-citalopram
12/07/2004US6828335 Oxazole or thiazole-ethyl-oxy-indane acetic acid derivatives; useful for the treatment of diseases such as diabetes, obesity, hyperlipidemia and atherosclerosis
12/07/2004CA2127374C Novel derivative of isoindolinone, its preparation and pharmaceutical compositions containing it
12/02/2004US20040242921 Resolution of racemic mixtures using an amine
12/01/2004CN1550553A Process for the preparation of (1S,4R) or (1R,4S)-1-amino-4-(methylol)-2-cyclopentene and its derivatives or its salts
12/01/2004CN1550500A Process for the preparation of (1S,4R) or (1R,4S)-4-(2-amino-6-chloro-9-H-purine-9-group)-2-cyclopentenyl-1-methanol or its salts
12/01/2004CN1550490A Process for the preparation of aminoalcohol and (1S,4Rú®or (1R,4S)-1-amino-4-(methylol)-2-cyclopentene or its salts
12/01/2004CN1177800C Method for the recemization of optically active amines
11/2004
11/24/2004EP1478760A1 Esterases with lipase activity
11/24/2004EP1478627A1 Method
11/18/2004US20040230065 Process for the preparation of 5-substituted isobenzofurans
11/18/2004US20040229923 Mixing a racemic mixture of enantiomers of pyrrolo[2,3-d]pyrimidine compounds in a solvent, with a resolving compound having a defined stereospecificity, to form a solution and with resolving agent being capable of binding with enantiomers to form a precipitate collecting precipitate and purifying
11/18/2004CA2524489A1 Method for the synthesis of 4-hydroxyisoleucine and the derivatives thereof
11/17/2004EP1477479A1 Process for the preparation of the D-(-)-tartrate salt of 1-(4-hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidin-1-YL)-1-propanol
11/17/2004CN1547566A Spliting method of (r)-(-)-2-hydroxyl-2-(2-chlorphenyl)acetic acid
11/16/2004US6818423 Process for the preparation of chiral α-hydroxycarboxylic acids
11/11/2004WO2004096873A1 Optically active acetylene polymer, film thereof, and optical resolution with the same
11/11/2004WO2000063175A3 Novel process
11/11/2004US20040225127 Process for manufacture of fosinopril sodium
11/10/2004EP0859764B1 PROCESS FOR THE CONTINUOUS PRODUCTION OF BASIC CYCLIC OPTICALLY ACTIVE alpha-AMINO ACIDS
11/03/2004EP1105371B1 Novel aryl sulphonamide amino acid esters and analogues
11/03/2004CN1173931C Acenaphthene derivative compound and its application
10/2004
10/27/2004EP1470121A1 Pyrimidine derivatives as rho-kinase inhibitors
10/27/2004EP1204636B1 3-oxopropane-1-sulphonic acids and sulphonates
10/26/2004US6809221 Process for preparing (+)-cis-sertraline
10/26/2004CA2120811C Improved process for manufacturing l-(-)-carnitine from waste products having opposite configuration
10/21/2004WO2004089871A1 TRANS-2-[(α-METHYLBENZYL)AMINO]CYCLOPENTANOL BEING PURE AS DIASTEREOISOMER
10/21/2004WO2003022784A9 Method for determining the enantiomer ratio trimethylcyclopentene derivatives
10/13/2004EP1465847A1 Highly homogeneous serum albumin as chiral selector
10/13/2004EP1383779B1 A process for manufacture of fosinopril sodium
10/07/2004US20040198974 applying deemed racemates to continuos enantioselective liquid chromatography like SMB (simulated moving bed); for industrial scale production of pure enantiomers of amino acids useful as intermediates in organic synthesis such as N-benzyloxycarbonyl-tert-leucine
10/06/2004EP1463699A2 Process for the production of 3-phenylisoserine
10/05/2004US6800766 Catalyzing the decyclization of racemic and diastereomeric epoxides mixtures in the presence of a non-racemic, chiral catalyst; pharmaceutical synthesis
09/2004
09/29/2004EP1461332A2 Production of chirally pure alpha-amino acids and n-sulfonyl alpha-amino acids
09/29/2004EP1071676A4 Kinetic resolution of olefins
09/23/2004US20040186298 Novel use of sulfamic acids as resolving agent
09/23/2004US20040186137 Heating a solution of a racemic mixture of terfenadine, carboxyterfenadine or an ester derivative and an equimolar amount of optically active resolving agent, (+)-di-para-toluoyltartaric acid or mandelic acid to solubilize the diastereomeric salt;cooling to precipitate the target salt; hydrolysis
09/23/2004US20040186042 2,6-dimethyl-2-(4-methylpent-4-enyl)-1-oxaspiro[2.5]oct-5-ene is converted to iso- beta -bisabolol by reductive opening of the epoxy group;
09/22/2004EP1458701A1 Method for the preparation of escitalopram
09/22/2004EP1458661A1 Separation of diastereoisomers
09/22/2004EP1163200B1 Method of industrial-scale purification of lactic acid
09/21/2004US6794544 Method for the preparation of tetrahydrobenzothiepines
09/21/2004CA2347758C Method for racemate splitting of 2-hydroxypropionic acids
09/16/2004US20040180952 Derivatives of (-)- and (+)-venlafaxine and methods of preparing and using the same
09/15/2004EP1457494A1 Processes for preparation of sulphostin and its analogues or intermediates thereof
09/15/2004CN1166633C New alpha-amino acid sulfuryl compounds, its preparing method and medicinal composition containing them
09/09/2004US20040176460 Use of L-(+)-tartaric acid in the separation of (R, R)-3-phenylisoserine or a derivative thereof from racemic mixtures
09/07/2004US6787655 Transition-metal-catalyzed asymmetric 1,4-addition of a nucleophile, e.g., hydride, to cyclic and acyclic enoates and enones and the catalyst containing a copper and an asymmetric bidentate bisphosphine ligand
09/01/2004CN1525963A Method for producing biperiden i
08/2004
08/25/2004EP1449842A1 Process for the preparation of pyrazolopyridine tartrates
08/24/2004US6781012 Process for the preparation of optically and chemically highly pure (R)- or (S)-α-hydroxycarboxylic acids
08/24/2004US6781006 Active catalysts for stereoselective ring-opening reactions
08/19/2004US20040159610 Macrocyclic antibiotics as separation agents
08/18/2004EP1446372A1 Recovery and recycling of chiral tartaric acid resolving agents
08/12/2004US20040157795 Derivatives of hyaluronan
08/12/2004US20040154987 Materials comprising saccharide cross-linked and chemically bonded to a support via urea linkages useful for chromatography and electrophoresis applications
08/11/2004EP1444188A1 Process for the preparation of optically pure or enriched racemic tetralone
08/11/2004EP1443921A1 PRODUCTION OF PURE STEREOISOMERS OF TRICYCLO 5.2.1.0 sp 2.6 /sp -DEC-9-YL XANTHOGENATE AND MEDICAMENTS THEREFROM
08/11/2004CN1520405A Process for prepn. of racemic citalopram and/or S-or R-citalopram by separation of mixture of R-and S-citalopram
08/11/2004CN1161335C Method for preparing substituted piperidine
08/05/2004US20040149660 Separatory agent for optical isomer
08/04/2004EP0918744B1 Racemic separation of ketamine
08/04/2004CN1160358C (8S,18S)-1,4,10,13,16-pentazatricyclo [16.3.0.04.8] heneicosane-9,17-diketone and its prepn process
07/2004
07/28/2004CN1515570A Preparation method of pyrazolo [4,3-C] pyridine-3-ketone L-tartate
07/22/2004WO2003037840A8 Process for the preparation of optically pure or enriched racemic tetralone
07/22/2004US20040142436 Process for the preparation of aminoalcohol derivatives and their further conversion to (1R,4S)-4-(2-amino-6-chloro-5-formamido-4-pyrimidinyl)-amino)-2-cyclopentenyl-1-methanol
07/08/2004WO2002072514A8 Methods and compositions for enantioselective oxidation reactions
07/08/2004US20040132998 Compositions and methods for separating amines and amino acids from their counter-enantiomers
07/01/2004WO2003003804A3 Process for the production of optically active 3-phenylisoserine
07/01/2004US20040127740 3, 4-disubstituted pyridine compounds;
06/2004
06/29/2004CA2133089C Novel cyclic amino acids and derivatives thereof
06/24/2004WO2004052883A2 Process for the separation of enantiomers
06/23/2004CN1154636C Process for preparnig intermediate in preparation of substd. peperidines
06/23/2004CN1154500C Process for preparing 1,3-oxygen-sulphur cyclopentane nucleotide like medicine composition
06/22/2004CA2084137C Optically active bead polymers containing fillers
06/16/2004EP1427684A1 Method for determining the enantiomer ratio trimethylcyclopentene derivatives
06/16/2004EP1339406B1 Piperazine derivatives, their preparation and their use for treating central nervous system (cns) disorders
06/16/2004EP1329453B1 Method for obtaining 4-(n-alkylamine)-5, 6-dihydro-4h-thieno-(2,3-b)-thiopyran-2-sulfonamide-7, 7-dioxides and intermediate products
06/10/2004US20040110957 producing racemic 3-hydroxy-3-(2-phenylethyl)-hexanoic acid at rapid reaction rates to form [R (R*,R*)]-N-[3-[1-[5,6-dihydro-4-hydroxy-2-oxo-6-(2-phenylethyl)-6-propyl-2H-pyran-3-yl]propyl]phenyl]-5-(trifluoromethyl)-2-pyridinesulfonamide
06/03/2004WO2004046714A1 Separating agent for optical isomer
06/03/2004WO2004026247A3 Compositions and methods for separating amines and amino acids from their counter-enantiomers
06/02/2004EP1424321A1 Synthesis of optically active cyclohexylphenylglycolate esters
06/01/2004US6743949 Process of obtainment of racemic cetamine enantiomers; process of obtainment of pharmaceutically acceptable salts from racemic cetamine enantiomes and use of pharmaceutically acceptable salts obtained by means of said mentioned process
06/01/2004US6743922 3-substituent highly resistant to rotation-4-tertiary amino-pyridine
06/01/2004US6743914 Using tertiary amine catalyst
06/01/2004US6743373 Reagent based on enantiopure amino acid in which amino group carries activating group to form active precursor of isocyanate group and carboxyl group is substituted; separation of enantiomers having free functional group
05/2004
05/27/2004WO2004043908A1 Process for converting a cis-trans mixture of substituted benzylidene amines into the pure cis isomer
05/27/2004US20040102652 For treatment of cardiovascular disorders/heart failure
05/27/2004US20040102646 Method of resolving optical isomers of amino acid derivative
05/27/2004CA2505797A1 Process for converting a cis-trans mixture of substituted benzylidene amines into the pure cis isomer
05/26/2004EP1422521A1 Separatory agent for optical isomer
05/19/2004EP1419125A1 Kinetic resolutions of chirat 3- and 3-substituted carboxylic acids
05/18/2004US6736967 Separating agent for enantiomeric isomers
05/18/2004CA2122254C The resolution of racemic verapamil
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