Patents
Patents for C07B 57 - Separation of optically-active organic compounds (3,737)
05/2008
05/28/2008EP1924540A2 Method for separating compound-forming chiral systems
05/28/2008CN101186561A 4,4',6,6'-tetra(trifluoromethyl)diphenyl-2,2'-diol and synthesizing method thereof
05/28/2008CN100390111C Separation of diastereoisomers
05/20/2008CA2155802C Enantiomerically pure pyridylcycloalkylethylamines and the salts thereof and processes for preparing them
05/15/2008US20080113864 (-)-Enantiomer of the 2-[2-(1-chloro-cyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-2,4-dihydro-[1,2,4]-triazole-3-thione
05/14/2008EP1919912A1 Process for enantiomeric separation of zopiclone
05/14/2008CN101177407A Extraction separating method of citalopram intermediate
05/13/2008US7371885 Cis-trans isomerisation of semicarbazone compounds
05/08/2008WO2008053652A1 Process for production of hydroxyadamantaneamine
05/07/2008EP1917235A1 Process for preparing enantiomerically enriched beta-amino acid derivatives
04/2008
04/29/2008US7365142 Polyelectrolyte complex films for analytical and membrane separation of chiral compounds
04/23/2008CN100383130C Process for resolving aimines that are useful for the treatment of disorders associated with insulin resistance syndrome.
04/23/2008CN100383119C Process for preparation of optically active indoline-2-carboxylic acid or derivative thereof
04/16/2008CN101161642A Method for decomposing chiral mobile phase additive RP-HPLC of fudosteine enantiomer
04/15/2008US7358396 can be resolved using optically active carboxylic acids or enzymes; compounds such as 1-benzyloxy-3-aminobutane
04/15/2008US7358386 Indane acetic acid derivatives and their use as pharmaceutical agents, intermediates, and method of preparation
04/15/2008US7358073 Process for the preparation of aminoalcohol derivatives and their further conversion to (1R, 4S)-4(2-amino-6-chloro-5-formamido-4- pyrimidinyl)-amino-2-cyclopentenyl-1-methanol
04/15/2008CA2337452C Process for the preparation of 4,5-diamino shikimic acid derivatives
04/08/2008CA2203183C Process for producing derivatives of 4a,5,9,10,11,12,-hexahydro-6h-benzofuro[3a,3,2-ef][2]benzazepine
04/03/2008WO2008038300A1 Organic-inorganic hybrid chiral sorbent and process for the preparation thereof
04/03/2008US20080081897 Separating agent for enantiomeric isomers and method of producing the same
04/03/2008CA2664855A1 Organic-inorganic hybrid chiral sorbent and process for the preparation thereof
04/02/2008CN101153020A (3S,4R)-4-(fluorophenyl)-3-hydroxymethyl-1-methyl piperidine and split method of antipodism thereof
03/2008
03/19/2008CN101143863A Resolution for 5-methyltetrahydrofolic acid and salifying method thereof
03/18/2008US7345202 Use of sulfamic acids as resolving agent
03/13/2008WO2008029785A1 Polysaccharide derivative and separating agent for optical isomer containing the same
03/12/2008EP1414809B1 Indane acetic acid derivatives and their use as pharmaceutical agents, intermediates, and method of preparation
03/11/2008CA2150355C Process of resolving phenylpropionic acids using alpha-methylbenzylamine
03/05/2008CN101137602A Process for preparing enantiopure E-(2S)-alkyl-5-halopent-4-enoic acids and esters
03/04/2008US7338945 (1R,4S) or (1S,4R)-1-Amino-4-(hydroxymethyl)-2-cyclopentene D- or L-hydrogen tartrate intermediates
02/2008
02/20/2008CN100369897C Diastereomeric salts of terfenadine
02/19/2008US7332553 Functional monomers for molecular recognition and catalysis
02/13/2008EP1885692A2 Process for the preparation of tamsulosin
02/13/2008CN100367948C Production of pure stereoisomers of tricyclo[5.2.1.02.6]-dec-9-yl xanthogenate and medicaments therefrom
02/07/2008WO2008015689A1 A process for the preparation of optically pure r (-) salbutamol and its pharmaceutically acceptable salts
02/07/2008US20080031939 Process for the preparation of armodafinil
01/2008
01/31/2008WO2008012047A1 Process for the preparation of (1r,2r)-3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol
01/31/2008WO2007092264B1 Kit for automated resolving agent selection and method thereof
01/31/2008CA2657104A1 Process for the preparation of (1r,2r)-3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol
01/29/2008US7323101 Separating agent for optical isomer and method for preparation thereof
01/24/2008WO2007060412A8 Improved apparatus and method for temperature controlled processes
01/24/2008US20080021110 Producing (-)-gossypol acetic acid co-crystals from (-)-gossypol acetone co-crystals, by substituting acetone in (-)-gossypol acetone co-crystals with acetic acid; use of gossypol acetic acid co-crystals and (-)-gossypol acetic acid co-crystals for inducing and for sensitizing cells to apoptosis
01/24/2008DE102006032061A1 Verfahren zur Herstellung von optisch aktiven Aminen A process for producing optically active amines
01/22/2008CA2431400C Process for preparing isomers of salbutamol
01/10/2008WO2007088571A3 A process for resolving racemic mixtures and a diastereoisomeric complex of a resolving agent and an enantiomer of interest
01/08/2008US7317127 Heating the tomoxetine racemate, a lower alcohol, an aromatic solvent, and (S)-(+)-mandelic acid; crystallizing (R)-(-)-tomoxetine (S)-(+)-mandelate
12/2007
12/21/2007WO2007111706A3 Organic compounds
12/19/2007EP1115693B9 SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL $i(TERTIARY)-HETEROALKYLAMINES USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY
12/18/2007CA2219308C New process for the preparation of ropivacaine hydrochloride monohydrate
12/13/2007US20070287860 Optical resolution of 3-carbamoylmethyl-5-methyl hexanoic acid
12/13/2007US20070287859 Intermediate in the synthesis of (S)-Pregabalin; precipitation
12/11/2007US7306734 Method for separation of enantiomeric isomers by simulated moving bed chromatography
12/05/2007CN100352437C Piperazine derivatives, their preparation and their use for treating central nervous system (CNS) disorders
11/2007
11/29/2007WO2007092264A3 Kit for automated resolving agent selection and method thereof
11/27/2007US7301044 Simultaneous resolution and salt formation of enantiomeric forms; simple, high yield
11/27/2007US7301023 Immunosuppressants; grafting of organs; rheumatic diseases
11/21/2007EP1856008A1 Process for preparing enantiopure e-(2s)-alkyl-5-halopent-4-enoic acids and esters
11/21/2007CN101074217A Method for obtaining endicawil critical intermediate by chromatogram separation
11/14/2007EP1294659B1 Process for isolating enantiomers of cetamine
11/06/2007US7291739 Chiral catalysts for asymmetric acylation and related transformations
10/2007
10/24/2007EP0946496B1 Process for resolving mixtures of carbocyclic stereoisomers
10/17/2007CN101056849A Process for the preparation of enantiomers of amidoacetonitrile compounds from their racemates
10/04/2007WO2007111706A2 Organic compounds
10/04/2007CA2629351A1 Organic compounds
10/03/2007EP1364933B1 Optical resolver and method of optically resolving alcohol with the same
10/03/2007CN101045664A Method for the separation and purifiction
09/2007
09/27/2007US20070225519 transforming optically active sec-alcohol into an activated compound with a leaving group; alkyating malonic acid in ether or ester solvents; added cosolvent is not hexamethyl phosphoric acid triamide; decarboxylation; 3-methylhexanoic acid; industrial scale; stereoselective inversion; no racemization
09/27/2007US20070225490 Cationic Oligomer of a Saccharide for Resolving Enantiomers and Asymmetric Synthesis
09/26/2007EP1338588B1 Method of resolving optical isomers of amino acid derivative
09/26/2007CN101041658A Resolution method for 2-hetero ring substituted dihydropyrimidine racemic compounds
09/20/2007WO2007105729A1 Process for production of cyclopropylamide compound
09/20/2007US20070219389 Process for Production of Cyclopentenenitrile Derivatives
09/20/2007US20070215549 high asymmetric recognizability in an aqueous mobile phase, or a separating agent for enantiomeric isomers containing a polysaccharide alicyclic ester derivative free from an aromatic group as an effective component; no large UV absorption
09/19/2007CN101037411A Splitting method of tetrahydroisoquinoline racemes
09/19/2007CN100338068C Process for preparing clopidogrel
09/19/2007CN100337996C method for synthesis of (2s)-indoline-2-carboxylic acid and use in the synthesis of perindopril
09/13/2007WO2007103221A2 An improved process for the preparation of armodafinil
09/13/2007WO2007075609A3 Production of chiral materials using crystallization inhibitors
09/13/2007CA2634133A1 An improved process for the preparation of armodafinil
09/12/2007EP1831132A2 Resolution of racemic organic acids with (1s, 4s)-4[3,4-dichlorophenyl]-1,2,3,4- tetrahydro-n-methyl-1-naphthaloneamine
09/06/2007DE102006009518A1 Organische Salze sowie Verfahren zur Herstellung von chiralen organischen Verbindungen Organic salts as well as methods for preparing chiral organic compounds
09/05/2007EP1366809B1 Separating agent for optical isomer
08/2007
08/30/2007WO2007097336A1 Process for producing (2r,3r)- and (2s,3s)-3-phenylisoserine derivatives
08/29/2007CN101024621A 2-nitro-benzoyl-imino-acenaphthylene derivative compound and use thereof
08/23/2007WO2007093764A1 Process for the cyanation of imines
08/22/2007CN1332933C Process for the synthesis of (is)-4,5-dimethoxy-1-(methylaminomethyl)-benzocyclobutane and uses thereof
08/22/2007CN101020626A Prepn process of high-purity optically active (-)-or(+)-gossypol
08/16/2007US20070190624 esterification with a cyclic anhydride or imide; acylated derivative containing a carboxylic acid group precipitates, easy to separate
08/15/2007CN101016251A Method of extracting and splitting phenylalanine by D-dialkyl tartrate
08/09/2007WO2007088571A2 A process for resolving racemic mixtures and a diastereoisomeric complex of a resolving agent and an enantiomer of interest
08/09/2007CA2638014A1 A process for resolving racemic mixtures and a diastereoisomeric complex of a resolving agent and an enantiomer of interest
08/08/2007EP1498404B1 Separating agent for optical isomer and method for preparation thereof
08/08/2007CN101014555A Methods for the separation of modafinil
08/08/2007CN101012176A Resolution method of optically pure 2-amino-2'-hydroxy-1,1-dinaphthalene (NOBIN)
08/01/2007EP1812385A1 Process for the preparation of enantiomers of amidoacetonitrile compounds from their racemates
07/2007
07/31/2007CA2367361C (-)-enantiomer of the 2-[2-(1- chlorocyclopropyl)-3- (2-chlorophenyl) -2- hydroxypropyl] -2,4- dihydro- [1,2,4] -triazole -3-thione
07/25/2007CN101003486A Preparation method of cycloamino alcohol of chirality fat
07/18/2007CN100999460A Decomposing process for salicylic acid and its isomer using hydrotalcite
07/12/2007DE19981703B4 Verfahren zur Erhöhung der Reinheit der racemischen Form von Metallocenkomplexen A process for increasing the purity of the racemic form of metallocene
07/12/2007DE102006000839A1 Preparation of optically active 3-phenylpropionic acid derivatives, used for preparing halo-phenyl compounds, comprises hydrogenating cis-isomer mixture of phenyl compound, crystallizing enantiomer mixture and isolating solid material
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