Patents for C07B 57 - Separation of optically-active organic compounds (3,737) |
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04/11/2012 | CN102408427A 莫西沙星中间体〔1s,6r〕—8—苄基—7,9—二氧—2,8—二氮杂双环[4.3.0]壬烷的制备方法 Moxifloxacin intermediate [1s, 6r] -8-benzyl-7,9-dioxo-2,8-diazabicyclo [4.3.0] nonane prepared |
04/11/2012 | CN102408313A R-3-丁炔-2-醇的制备方法 Preparation R-3- butyn-2-ol |
04/11/2012 | CN102408289A 一种应用蛋白质功能化磁性纳米颗粒拆分手性药物的方法 A protein function chiral drug particle method applied magnetic nanoparticles |
04/11/2012 | CN102408288A 应用蛋白质功能化磁性纳米颗粒拆分手性药物的方法 Chiral drug particles Application protein functional magnetic nanoparticles |
04/04/2012 | CN102399169A 一种用于手性羧酸对映体分析和拆分的化合物及其制备方法 A chiral carboxylic acid compounds and methods of analysis and resolution of enantiomers for |
04/04/2012 | CN102399158A 一种化学制备麻黄碱的工艺 A chemical process for the preparation of ephedrine |
03/28/2012 | EP2183201B1 Process for the resolution of zopiclone and intermediate compounds |
03/28/2012 | CN102391394A 6<A>-(3-methoxy chloropropylamine)-beta-cyclodextrin with broad spectrum chiral resolution capacity and preparation method and application thereof |
03/28/2012 | CN102389782A Triazole singly-bonded fully-substituted cyclodextrin silica gel chiral fixed phase and preparation method thereof |
03/15/2012 | WO2012033188A1 Method for producing optically active amino acid |
03/15/2012 | WO2012033187A1 Method for producing optically active 2-aminobutyric acid |
03/07/2012 | CN101570550B Method for synthesizing chiral ferrocene diphosphine ligand |
03/01/2012 | US20120053179 Rho-Kinase Inhibitors |
02/22/2012 | EP1719758B1 Process for producing monatin |
02/21/2012 | CA2436323C Process for preparing clopidogrel |
02/16/2012 | US20120041235 Process for the preparation of (r)-2-(3-diisopropylamino)-1-phenylpropyl)-4methylphenol and salts thereof |
02/16/2012 | US20120041225 Kit for automated resolving agent selection and method thereof |
02/15/2012 | CN102356061A Method for producing bicyclic g-amino acid derivative |
02/15/2012 | CN102351810A Resolution method of levocetirizine chiral intermediates |
02/01/2012 | EP2412704A2 Method for obtaining optically pure amino acids |
02/01/2012 | EP2412700A1 Method for producing bicyclic gamma-amino acid derivative |
02/01/2012 | CN102336653A Preparation method of optically pure chiral 2-chloromandelic acid |
01/25/2012 | EP2280974B1 Stereoselective synthesis of certain trifluoromethyl-substituted alcohols |
01/25/2012 | CN101735185B Racemization method for optically active 3-butyl phthalide |
01/18/2012 | EP2407447A1 Method for producing optically active 2-hydroxy ester and novel intermediate compound |
01/11/2012 | CN102317248A Process for producing optically active carboxylic acid |
01/11/2012 | CN102311504A Polysaccharide derivative and preparation method thereof and separating agent |
01/11/2012 | CN101759629B Novel preparation method for sitafloxacin intermediate |
01/10/2012 | US8092677 Separating agent for an enantiomeric isomer |
01/05/2012 | WO2012001571A1 New process for the synthesis of tapentadol and intermediates thereof |
01/05/2012 | WO2012000308A1 A method for resolution of tetrabenazine |
01/05/2012 | US20120004463 Resolution of 4,5-dimethoxy-1-(methylaminomenthyl)-benzocyclobutane |
12/29/2011 | DE102011101183A1 New enantiomerically enriched aromatic azo compounds useful for the preparation of enantiomerically enriched amino alcohol compound and amino acid compound |
12/28/2011 | EP2399916A1 Process and intermediates for the preparation of aspartic acetal caspase ihnhibitors |
12/28/2011 | EP2399915A1 Process and intermediates for the preparation of aspartic acetal caspase inhibitors |
12/28/2011 | CN102295551A S-(-)-α-苯乙胺拆分消旋萘普生 S - (-) - α- phenethylamine Separation of racemic naproxen |
12/28/2011 | CN101654429B 一种拆分获取s-(-)-氨氯地平的方法 One kind of split get s - (-) - amlodipine methods |
12/22/2011 | WO2011158720A1 Method for producing (1r, 2s)-1-amino-2-vinyl cyclopropane carboxylic acid ester that has improved optical purity |
12/22/2011 | US20110313199 processes for preparing substantially pure arformoterol and its intermediates |
12/21/2011 | CN101940947B Method for preparing polystyrene resin-immobilized Salon-Co (III) catalyst |
12/21/2011 | CN101544629B 一种分离罗替戈汀、苯海索对映异构体的方法 An rotigotine, trihexyphenidyl enantiomer separation method |
12/14/2011 | EP1935866B1 Process for producing optically active fluorobenzyl alcohol |
12/14/2011 | CN102276761A 单取代铵基正电型-β-环糊精及其制备方法 Mono-substituted ammonium group positive type -β- cyclodextrin and its preparation method |
12/06/2011 | CA2455620C Indane acetic acid derivatives and their use as pharmaceutical agents, intermediates, and method of preparation |
11/29/2011 | US8067640 Method for the separation of intermediates which may be used for the preparation of escitalopram |
11/23/2011 | CN1918112B Method for the separation of intermediates which may be used for the preparation of escitalopram |
11/22/2011 | US8063251 Process for the preparation of optically pure R (−) salbutamol and its pharmaceutically acceptable salts |
11/22/2011 | CA2352324C Derivatives of (-)-venlafaxine and methods of preparing and using the same |
11/16/2011 | CN102241555A Method for preparing photoactived amino acid through resolution |
11/02/2011 | CN102229584A Method for preparing D-(-)- or L-(+)-pantoic acid lactone by splitting pantoic acid lactone |
10/26/2011 | CN102225974A Double-substituted 6-alkyl imidazolium-6-ammonium-beta-cyclodextrin with double positive electricity centers and preparation method thereof |
10/26/2011 | CN102225936A Processes for producing compound |
10/26/2011 | CN102225885A Method for increasing optical purity of alpha-terpineol |
10/20/2011 | WO2011129365A1 Antitumor agent |
10/13/2011 | WO2011124934A1 Industrial process for the synthesis of (s)-(+)-pregabalin |
10/13/2011 | US20110251407 Process for production of optically active organic carboxylic acid |
10/11/2011 | CA2400482C Bupropion metabolites and methods of their synthesis and use |
10/05/2011 | EP1676852B1 Process for producing optically active dihydropyridinephosphonic ester |
10/05/2011 | CN102207494A Method for simultaneously determining four optical isomers of palonosetron hydrochloride |
10/05/2011 | CN102206138A Method for separating and purifying two fragrance precursors from tobacco |
09/28/2011 | EP2368871A1 Process for the preperation of (1R,2R)-3-(3-dimethylamino-1-ethyl-2-methylpropyl)-phenol |
09/28/2011 | EP2368870A1 Process for producing optically active carboxylic acid |
09/28/2011 | CN102203047A Process for production of optically active organic carboxylic acid |
09/14/2011 | CN101412680B Preparation of high-purity eptazocine intermediate |
09/14/2011 | CN101328161B Method for separating and detecting nebivolol hydrochloride impurity by liquid phase chromatography |
09/13/2011 | CA2691149C Process for the preparation of racemic citalopram and/or s- or r-citalopram by separation of a mixture of r-and s-citalopram |
08/31/2011 | CN102167827A Optically active thermotropic liquid crystal polyesterimide based on trimellitic anhydride, preparation method and application thereof |
08/31/2011 | CN102167826A Optically active polyamide imide and preparation method as well as application thereof |
08/25/2011 | WO2011102388A1 Method for producing 1-amino-1-alkoxycarbonyl-2-vinylcyclopropane |
08/24/2011 | EP2360160A1 Intermediates and their use for producing benzoxazine derivative |
08/24/2011 | EP2360150A1 Method for the separation of intermediates which may be used for the preparation of escitalopram |
08/17/2011 | CN102153483A Axial chirality vicinal diamine compound and preparation method thereof |
08/17/2011 | CN101429180B Process for producing S-tetrahydrochysene furoic acid |
08/17/2011 | CN101230080B simulated moving bed chromatography separation of 20(S) and 20(R)-ginsenoside Rg3 enantiomer |
08/10/2011 | EP1609781B1 Optical resolution of (1-benzyl-4-methylpiperidin-3-yl)-methylamine |
08/09/2011 | CA2428039C Serotonergic agents |
08/03/2011 | EP2351729A1 Process for production of optically active organic carboxylic acid |
08/03/2011 | CN102143928A Process for enantioseparation of chiral systems with compound formation using two subsequent crystallization steps |
08/03/2011 | CN101597277B Novel method for preparing S-pantoprazole and salt |
07/27/2011 | CN102134310A Optical-rotation polyester imide based on symmetrical imide diacid and preparation method and application thereof |
07/21/2011 | WO2011086566A1 Method of resolution of (rs) - 1, 1 ' - bi - 2 - naphthol for obtaining enantiomeric pure i.e. (s) - (-) " 1, 1 ' "bi - 2 -naphthol and/or (r) - ( ) - 1, 1 ' - bi - 2 - naphthol via co - crystal formation with optically active derivatives of gamma -amino acids |
07/20/2011 | EP2344435A2 Process of isolating enantiomer components from enantiomer mixtures by particle-size-controlled crystallization |
07/20/2011 | CN102126944A Method for preparing single configuration mandelic acid or mandelic acid derivative by using chiral resolving agent |
07/06/2011 | CN101037411B Splitting method of tetrahydroisoquinoline racemes |
06/30/2011 | WO2011078172A1 Process for production of optically active 3-substituted glutaric acid monoamide |
06/29/2011 | CN102112425A Process of isolating enantiomer components from enantiomer mixtures by particle-size-controlled crystallization |
06/23/2011 | WO2011073300A1 Process for the resolution of enantiomers by preferential evaporative crystallization |
06/23/2011 | CA2784236A1 Process for the resolution of enantiomers by preferential evaporative crystallization |
06/22/2011 | EP2334620A2 Process for enantioseparation of chiral systems with compound formation using two subsequent crystallization steps |
06/16/2011 | WO2011070028A1 Kinetic resolution |
06/15/2011 | EP2332895A1 Kinetic Resolution |
06/15/2011 | CN102099331A Method for producing optically active aminoalcohol derivative |
06/15/2011 | CN102093152A Method for splitting chiral medicament |
06/15/2011 | CN101186561B 4,4',6,6'-tetra(trifluoromethyl)diphenyl-2,2'-diol and synthesizing method thereof |
06/15/2011 | CN101045664B Method for the separation and purifiction |
06/08/2011 | CN1950364B Processes and intermediates for the preparation of aspartic acetal caspase inhibitors |
06/08/2011 | CN101468987B Method for splitting 2-heterocycle substituted dihydropyrimidine racemic compound |
06/08/2011 | CN101463024B Method for preparing RRRS and SSSR type nebivolol intermediate mixture |
05/31/2011 | CA2172282C Chiral surfactants and methods for their use in chiral separations |
05/26/2011 | WO2011061934A1 Method for producing optically active bicyclo [3.1.0] hexane derivative using oxygen |