Patents
Patents for C07B 57 - Separation of optically-active organic compounds (3,737)
04/2012
04/11/2012CN102408427A 莫西沙星中间体〔1s,6r〕—8—苄基—7,9—二氧—2,8—二氮杂双环[4.3.0]壬烷的制备方法 Moxifloxacin intermediate [1s, 6r] -8-benzyl-7,9-dioxo-2,8-diazabicyclo [4.3.0] nonane prepared
04/11/2012CN102408313A R-3-丁炔-2-醇的制备方法 Preparation R-3- butyn-2-ol
04/11/2012CN102408289A 一种应用蛋白质功能化磁性纳米颗粒拆分手性药物的方法 A protein function chiral drug particle method applied magnetic nanoparticles
04/11/2012CN102408288A 应用蛋白质功能化磁性纳米颗粒拆分手性药物的方法 Chiral drug particles Application protein functional magnetic nanoparticles
04/04/2012CN102399169A 一种用于手性羧酸对映体分析和拆分的化合物及其制备方法 A chiral carboxylic acid compounds and methods of analysis and resolution of enantiomers for
04/04/2012CN102399158A 一种化学制备麻黄碱的工艺 A chemical process for the preparation of ephedrine
03/2012
03/28/2012EP2183201B1 Process for the resolution of zopiclone and intermediate compounds
03/28/2012CN102391394A 6<A>-(3-methoxy chloropropylamine)-beta-cyclodextrin with broad spectrum chiral resolution capacity and preparation method and application thereof
03/28/2012CN102389782A Triazole singly-bonded fully-substituted cyclodextrin silica gel chiral fixed phase and preparation method thereof
03/15/2012WO2012033188A1 Method for producing optically active amino acid
03/15/2012WO2012033187A1 Method for producing optically active 2-aminobutyric acid
03/07/2012CN101570550B Method for synthesizing chiral ferrocene diphosphine ligand
03/01/2012US20120053179 Rho-Kinase Inhibitors
02/2012
02/22/2012EP1719758B1 Process for producing monatin
02/21/2012CA2436323C Process for preparing clopidogrel
02/16/2012US20120041235 Process for the preparation of (r)-2-(3-diisopropylamino)-1-phenylpropyl)-4methylphenol and salts thereof
02/16/2012US20120041225 Kit for automated resolving agent selection and method thereof
02/15/2012CN102356061A Method for producing bicyclic g-amino acid derivative
02/15/2012CN102351810A Resolution method of levocetirizine chiral intermediates
02/01/2012EP2412704A2 Method for obtaining optically pure amino acids
02/01/2012EP2412700A1 Method for producing bicyclic gamma-amino acid derivative
02/01/2012CN102336653A Preparation method of optically pure chiral 2-chloromandelic acid
01/2012
01/25/2012EP2280974B1 Stereoselective synthesis of certain trifluoromethyl-substituted alcohols
01/25/2012CN101735185B Racemization method for optically active 3-butyl phthalide
01/18/2012EP2407447A1 Method for producing optically active 2-hydroxy ester and novel intermediate compound
01/11/2012CN102317248A Process for producing optically active carboxylic acid
01/11/2012CN102311504A Polysaccharide derivative and preparation method thereof and separating agent
01/11/2012CN101759629B Novel preparation method for sitafloxacin intermediate
01/10/2012US8092677 Separating agent for an enantiomeric isomer
01/05/2012WO2012001571A1 New process for the synthesis of tapentadol and intermediates thereof
01/05/2012WO2012000308A1 A method for resolution of tetrabenazine
01/05/2012US20120004463 Resolution of 4,5-dimethoxy-1-(methylaminomenthyl)-benzocyclobutane
12/2011
12/29/2011DE102011101183A1 New enantiomerically enriched aromatic azo compounds useful for the preparation of enantiomerically enriched amino alcohol compound and amino acid compound
12/28/2011EP2399916A1 Process and intermediates for the preparation of aspartic acetal caspase ihnhibitors
12/28/2011EP2399915A1 Process and intermediates for the preparation of aspartic acetal caspase inhibitors
12/28/2011CN102295551A S-(-)-α-苯乙胺拆分消旋萘普生 S - (-) - α- phenethylamine Separation of racemic naproxen
12/28/2011CN101654429B 一种拆分获取s-(-)-氨氯地平的方法 One kind of split get s - (-) - amlodipine methods
12/22/2011WO2011158720A1 Method for producing (1r, 2s)-1-amino-2-vinyl cyclopropane carboxylic acid ester that has improved optical purity
12/22/2011US20110313199 processes for preparing substantially pure arformoterol and its intermediates
12/21/2011CN101940947B Method for preparing polystyrene resin-immobilized Salon-Co (III) catalyst
12/21/2011CN101544629B 一种分离罗替戈汀、苯海索对映异构体的方法 An rotigotine, trihexyphenidyl enantiomer separation method
12/14/2011EP1935866B1 Process for producing optically active fluorobenzyl alcohol
12/14/2011CN102276761A 单取代铵基正电型-β-环糊精及其制备方法 Mono-substituted ammonium group positive type -β- cyclodextrin and its preparation method
12/06/2011CA2455620C Indane acetic acid derivatives and their use as pharmaceutical agents, intermediates, and method of preparation
11/2011
11/29/2011US8067640 Method for the separation of intermediates which may be used for the preparation of escitalopram
11/23/2011CN1918112B Method for the separation of intermediates which may be used for the preparation of escitalopram
11/22/2011US8063251 Process for the preparation of optically pure R (−) salbutamol and its pharmaceutically acceptable salts
11/22/2011CA2352324C Derivatives of (-)-venlafaxine and methods of preparing and using the same
11/16/2011CN102241555A Method for preparing photoactived amino acid through resolution
11/02/2011CN102229584A Method for preparing D-(-)- or L-(+)-pantoic acid lactone by splitting pantoic acid lactone
10/2011
10/26/2011CN102225974A Double-substituted 6-alkyl imidazolium-6-ammonium-beta-cyclodextrin with double positive electricity centers and preparation method thereof
10/26/2011CN102225936A Processes for producing compound
10/26/2011CN102225885A Method for increasing optical purity of alpha-terpineol
10/20/2011WO2011129365A1 Antitumor agent
10/13/2011WO2011124934A1 Industrial process for the synthesis of (s)-(+)-pregabalin
10/13/2011US20110251407 Process for production of optically active organic carboxylic acid
10/11/2011CA2400482C Bupropion metabolites and methods of their synthesis and use
10/05/2011EP1676852B1 Process for producing optically active dihydropyridinephosphonic ester
10/05/2011CN102207494A Method for simultaneously determining four optical isomers of palonosetron hydrochloride
10/05/2011CN102206138A Method for separating and purifying two fragrance precursors from tobacco
09/2011
09/28/2011EP2368871A1 Process for the preperation of (1R,2R)-3-(3-dimethylamino-1-ethyl-2-methylpropyl)-phenol
09/28/2011EP2368870A1 Process for producing optically active carboxylic acid
09/28/2011CN102203047A Process for production of optically active organic carboxylic acid
09/14/2011CN101412680B Preparation of high-purity eptazocine intermediate
09/14/2011CN101328161B Method for separating and detecting nebivolol hydrochloride impurity by liquid phase chromatography
09/13/2011CA2691149C Process for the preparation of racemic citalopram and/or s- or r-citalopram by separation of a mixture of r-and s-citalopram
08/2011
08/31/2011CN102167827A Optically active thermotropic liquid crystal polyesterimide based on trimellitic anhydride, preparation method and application thereof
08/31/2011CN102167826A Optically active polyamide imide and preparation method as well as application thereof
08/25/2011WO2011102388A1 Method for producing 1-amino-1-alkoxycarbonyl-2-vinylcyclopropane
08/24/2011EP2360160A1 Intermediates and their use for producing benzoxazine derivative
08/24/2011EP2360150A1 Method for the separation of intermediates which may be used for the preparation of escitalopram
08/17/2011CN102153483A Axial chirality vicinal diamine compound and preparation method thereof
08/17/2011CN101429180B Process for producing S-tetrahydrochysene furoic acid
08/17/2011CN101230080B simulated moving bed chromatography separation of 20(S) and 20(R)-ginsenoside Rg3 enantiomer
08/10/2011EP1609781B1 Optical resolution of (1-benzyl-4-methylpiperidin-3-yl)-methylamine
08/09/2011CA2428039C Serotonergic agents
08/03/2011EP2351729A1 Process for production of optically active organic carboxylic acid
08/03/2011CN102143928A Process for enantioseparation of chiral systems with compound formation using two subsequent crystallization steps
08/03/2011CN101597277B Novel method for preparing S-pantoprazole and salt
07/2011
07/27/2011CN102134310A Optical-rotation polyester imide based on symmetrical imide diacid and preparation method and application thereof
07/21/2011WO2011086566A1 Method of resolution of (rs) - 1, 1 ' - bi - 2 - naphthol for obtaining enantiomeric pure i.e. (s) - (-) " 1, 1 ' "bi - 2 -naphthol and/or (r) - ( ) - 1, 1 ' - bi - 2 - naphthol via co - crystal formation with optically active derivatives of gamma -amino acids
07/20/2011EP2344435A2 Process of isolating enantiomer components from enantiomer mixtures by particle-size-controlled crystallization
07/20/2011CN102126944A Method for preparing single configuration mandelic acid or mandelic acid derivative by using chiral resolving agent
07/06/2011CN101037411B Splitting method of tetrahydroisoquinoline racemes
06/2011
06/30/2011WO2011078172A1 Process for production of optically active 3-substituted glutaric acid monoamide
06/29/2011CN102112425A Process of isolating enantiomer components from enantiomer mixtures by particle-size-controlled crystallization
06/23/2011WO2011073300A1 Process for the resolution of enantiomers by preferential evaporative crystallization
06/23/2011CA2784236A1 Process for the resolution of enantiomers by preferential evaporative crystallization
06/22/2011EP2334620A2 Process for enantioseparation of chiral systems with compound formation using two subsequent crystallization steps
06/16/2011WO2011070028A1 Kinetic resolution
06/15/2011EP2332895A1 Kinetic Resolution
06/15/2011CN102099331A Method for producing optically active aminoalcohol derivative
06/15/2011CN102093152A Method for splitting chiral medicament
06/15/2011CN101186561B 4,4',6,6'-tetra(trifluoromethyl)diphenyl-2,2'-diol and synthesizing method thereof
06/15/2011CN101045664B Method for the separation and purifiction
06/08/2011CN1950364B Processes and intermediates for the preparation of aspartic acetal caspase inhibitors
06/08/2011CN101468987B Method for splitting 2-heterocycle substituted dihydropyrimidine racemic compound
06/08/2011CN101463024B Method for preparing RRRS and SSSR type nebivolol intermediate mixture
05/2011
05/31/2011CA2172282C Chiral surfactants and methods for their use in chiral separations
05/26/2011WO2011061934A1 Method for producing optically active bicyclo [3.1.0] hexane derivative using oxygen
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