Patents for C07B 53 - Asymmetric syntheses (6,231)
07/2003
07/31/2003CA2471389A1 Process for the preparation of nonracemic syn-1-(4-hydroxy-phenyl)-2-(4-hydroxy-4-phenyl-piperidin-1yl)-1-propanol compounds
07/30/2003EP1330245A1 Pravastatin sodium substantially free of pravastatin lactone and epi-pravastatin, and compositions containing same
07/30/2003EP1180035A4 NON-CALCEMIC, ANTIPROLIFERATIVE, TRANSCRIPTIONALLY ACTIVE SULFUR-CONTAINING ANALOGS OF 1$g(a), 25-DIHYDROXY VITAMIN D 3?
07/30/2003CN1433397A Method for the prepararation of enantiomerically enriched compounds
07/29/2003US6600062 Enantioselectivity; epoxidizing and hydrolyzing the geranyloxy compound
07/24/2003WO2003059902A1 Method for producing thioctic acid
07/24/2003WO2003059512A1 Immobilized catalyst for heterogeneous catalysis
07/24/2003WO2003059335A1 Phenyl sulfoxides and phenyl sulfones
07/24/2003WO2003031456A3 Ligands for asymmetric reactions
07/24/2003WO2002022529A3 1,4-diaryl-2,3-difluoro-2-butene insecticidal and acaricidal agents
07/24/2003US20030139628 Process for the preparation of optically active amines or salts thereof
07/24/2003US20030139625 Hydrolysis, enantioselective hydrogenation in presence of a hydrogenation catalyst metal complexes
07/24/2003US20030139614 Catalyzing the decyclization of racemic and diastereomeric epoxides mixtures in the presence of a non-racemic, chiral catalyst; pharmaceutical synthesis
07/24/2003US20030139285 Novel asymmetric phosphine ligand
07/24/2003CA2473374A1 Phenyl sulfoxides and phenyl sulfones
07/23/2003EP1025083B1 Process for stereoselective synthesis of prostacyclin derivatives
07/22/2003US6596898 Making a 2-fluoro-2-chlorocyclopropanecarboxylic acid derivative stereoselectively in high yield by reacting a diazoacetic acid derivative with 1-fluoro-1-chloroethylene using metal catalyst having chiral ligands
07/22/2003US6596887 Reacting a ruthenium-phosphine complex with a specific optically active chiral diamine to deactivate one of the enantiomers and with another diamine to activate the other enantiomers
07/22/2003US6596870 Asymmetric hydride reductions of carbonyl groups using a chiral non-racemic phase transfer catalyst, a helper nucleophile, and a sterically bulky reagent nucleophile
07/17/2003WO2003057649A2 Ammonium ionophore
07/17/2003CA2471446A1 Ammonium ionophore
07/16/2003EP1326846A1 Process for preparation of integrin receptor antagonist intermediates
07/16/2003CN1430677A Process for preparation of enantiomerically enriched esters and alcohols
07/15/2003US6593489 Catalytic stereoselective hydrogenation
07/15/2003US6593350 For therapy of depression, obsessive compulsive disorder, panic attacks, generalized anxiety disorder, social anxiety disorder, sexual dysfunction, eating disorders, obesity, addictive disorders caused by ethanol or cocaine abuse
07/10/2003US20030130488 An asymmetric catalyst that can epoxidize unsaturated amides or ketones
07/10/2003US20030129713 Reacting the ketals or acetals with a cyanide donor in the presence of an (R)- or (S)- hydroxynitrile lyase
07/09/2003EP1325908A1 Process for the preparation of an enantiomerically enriched thio compound
07/09/2003EP1325013A2 Catalyst for asymmetric (transfer) hydrogenation
07/09/2003EP1292602A4 New chiral salen catalyst and methods for the preparation of chiral compounds from racemic epoxides by using new catalyst
07/09/2003EP1233939A4 Process for preparing optically active alpha-hydroxy acids and derivatives thereof
07/09/2003EP1173430B1 Enantiomers of mercapto lactones and processes for their synthesis
07/09/2003EP1155024B1 Chiral diazaphospholidine ligands
07/09/2003EP1064244B1 Method for separating a diphosphine diastereoisomers
07/09/2003CN1429206A 磺酰胺衍生物 Sulfonamide derivatives
07/09/2003CN1429204A Process for preparing biphenyl compounds
07/09/2003CN1429197A Shortened synthesis of 3,3-diarylpropylamine derivatives
07/09/2003CN1113874C Benzocycloalkylazolethione derivatives
07/08/2003CA2153549C New benzothiadiazine derivative, process for preparing the same and pharmaceutical compositions containing said derivative
07/03/2003WO2003053916A1 Process for preparing 2-(substituted phenyl) - 2 - hydroxy-ethyl carbamates
07/03/2003WO2003053886A1 Volume gassing
07/03/2003WO2003053176A2 Method and compositions for imparting cooling effect to tobacco products
07/03/2003WO2002094849A3 Process for the production of 6, 7 - dihydroxy steroid compounds by allylic oxidation of steroid - 5 - ene compounds to steroid - 5 - ene - 7 - one compounds followed by hydroboration and oxidation and intermediates of this process
07/03/2003US20030125575 Process for the preparation of(R)-2-bromo-3-phenyl -propionic acid
07/03/2003US20030125563 Asymmetric 1,4-reductions of and 1,4-additions to enoates and related systems
07/03/2003CA2681964A1 Process for preparing 2-(substituted phenyl) - 2 - hydroxy-ethyl carbamates
07/02/2003EP1323828A2 Method for the preparation of enantiomerically enriched cyanohydrines using acetals or ketals as substratess
07/02/2003EP1323724A2 Novel ruthenium complexes and process for preparing alcoholic compounds using these
07/02/2003EP1322652A1 Stereoselective process for preparing cyclohexyl amine derivatives
07/02/2003CN1427840A Azabicyclic carbamates and their use as alpha-7 nicotinic acetyl choline receptor agonists
07/02/2003CN1427829A Substituted phenylacetamides and their use as glucokinase activators
07/01/2003US6586616 Process for preparing(R)-4-cyano-3-hydroxybutyric acid ester
07/01/2003US6586456 Corticotropin releasing factor (CRF) antagonists such as (4-(2-chloro-4-methoxy-5-methylphenyl)-5-methylthiazol-2-yl)(( (1-(3-fluoro-4-methylphenyl)-2-methoxyethyl))prop-2-ynylamine, prepared by alkylation with propagyl bromide
07/01/2003US6586434 Method for the preparation of tetrahydrobenzothiepines
07/01/2003CA2120919C New ligands for asymmetric dihydroxylation: multiple cinchona alkaloid units attached to a central heterocyclic core
06/2003
06/28/2003CA2414265A1 Novel ruthenium complexes and process for preparing alcoholic compounds using these
06/27/2003CA2415168A1 Process for preparing enantiomer-enriched cyanohydrins using acetals orketals as substrates
06/26/2003WO2003051827A1 Process for the preparation of an enantiomerically enriched thio compound
06/26/2003US20030120122 Hydrogenation catalysts
06/26/2003US20030120091 Method for producing optically active lactone compounds by using salen cobalt complexes having a cis-beta structure
06/26/2003US20030120088 Hydrogenation catalyst for asymmetrically reducing prochiral ketone or imine
06/26/2003US20030119664 Hydrogenation catalyst containing phosphite group
06/26/2003US20030119659 Ligands and asymmetric catalysts made by using the same
06/26/2003US20030118483 Pressurized chemical reactor; sealing
06/25/2003EP1321452A2 Process for the preparation of optically active amines or salts thereof
06/25/2003EP1320518A2 Preparation of enantiomerically-enriched cyclopropylalanine derivatives
06/25/2003EP1235792A4 Preparation of [4s-(4alpha,7alpha,10abeta)]-4-amino-octahydro-5-oxo-7h-pyrido 2,1-b] 1,3]thiazepine-7-carboxylic acid, methyl ester and salts thereof via novel disulfides
06/25/2003CN1425655A Method for preparing pyrimidine derivative
06/25/2003CN1112354C Stereo specific prepn. of chiral 1-aryl-and 1-heteroaryl-2-substituted ethyl-2-amines
06/24/2003US6583309 Ureas and compositions thereof for treating cancer, inflammation, or a viral infection
06/24/2003US6583306 Forming dioxolane derivative of citramalic acid; replacing free carboxylic acid with leaving group; coupling with hydroxyl, amino, thiol, sulphinyl or sulphonyl reactive compound; deprotecting; amidation with aniline derivitive
06/24/2003US6583305 Ferrocene-based diphosphonites for asymmetrical catalysis
06/19/2003WO2003050063A2 PROCESS FOR THE SYNTHESIS OF CHIRALLY PURE β-AMINO-ALCOHOLS
06/19/2003WO2003050062A2 PRODUCTION OF CHIRALLY PURE α-AMINO ACIDS ADN N-SULFONYL α-AMINO ACIDS
06/19/2003WO2003049681A2 Synthesis of 4,5-dihydro-pyrazolo [3,4-c] pyrid-2-ones
06/19/2003WO2003029267A3 METHOD OF PRODUCING 17β-(SUBSTITUTED)-3-OXO-Δ1,2-4-AZASTEROIDS AND INTERMEDIATES
06/19/2003CA2470111A1 Production of chirally pure .alpha.-amino acids and n-sulfonyl .alpha.-amino acids
06/19/2003CA2469021A1 Process for the synthesis of chirally pure .beta.-amino-alcohols
06/18/2003EP1319660A1 Optically active azetidincarboxamide-coordinated transition metal complexes as catalysts in asymmetric reduction
06/18/2003EP1318990A1 Process for preparing optically active epoxides
06/18/2003EP0757677B1 Benzocyclohexylimidazolethione derivatives
06/17/2003US6580003 Catalytic asymmetric desymmetrization of meso compounds
06/12/2003WO2003048173A1 Chiral ligands for asymmetric catalysis
06/12/2003WO2003048117A2 Propanolaminomethyltetralines, their preparation and pharmaceutical composition comprising same
06/12/2003WO2003048102A1 Method for the production of dihydroxycarboxylate esters
06/12/2003US20030109712 Preparation of optically active alpha-hydroxyethers
06/12/2003CA2468437A1 Method for the production of dihydroxycarboxylate esters
06/11/2003EP1318156A1 Novel asymmetric phosphine ligand
06/11/2003EP1318155A1 Novel asymmetric phosphine ligand
06/11/2003EP1317461A1 4-cyclohexyl-1,3,2-oxazaborolidine chiral accessories
06/11/2003EP1317460A1 Compounds containing oxazolidinone moiety and uses thereof
06/11/2003EP1317427A1 Method for producing chiral compounds
06/10/2003US6576772 Chiral phosphines, transition metal complexes thereof and uses thereof in asymmetric reactions
06/05/2003WO2003045878A2 2,w-diaminocarboxylic acid compounds
06/05/2003US20030105341 Process for producing optically active gamma-butyrolactone
06/05/2003US20030105306 Transition metal oxo, sulfido and amido complexes as catalysts of nucleophilic addition reactions
06/05/2003US20030105113 Enantiomers of 1-[ (4-chlorophenyl) phenylmethyl ] -4-[ (4-methylphenyl) sulfonyl ] piperazine
06/05/2003US20030105112 Enantiomers of 1-[(4-chlorophenyl) phenylmethyl]-4-[(4-methylphenyl) sulfonyl] piperazine
06/05/2003CA2467665A1 2,w-diaminocarboxylic acid compounds
06/03/2003US6573395 Zinc complex with a chiral ligand, such as diethylzinc((S,S)-N-N'-ethylene-bis-(1-phenylethylamine))
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