| Patents for C40B 50 - Methods of creating libraries, e.g. combinatorial synthesis (5,219) |
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| 06/19/2008 | US20080146459 Protein Array and Process for Producing the Same |
| 06/19/2008 | US20080146458 Process for the preparation of oxazolidinones and method of use thereof |
| 06/19/2008 | US20080145839 Method and Nucleic Acids For the Differentiation of Astrocytoma, Oligoastrocytoma and Oligodenroglioma Tumor Cells |
| 06/17/2008 | US7387865 mixture of sulfonium or iodonium acid generators and nonionic surfactants, used to form analysis apparatus on solid substrates |
| 06/12/2008 | WO2008070375A2 Selection of dna adaptor orientation |
| 06/12/2008 | US20080139409 DNA Probe Synthesis on Chip on Demand By Mems Ejector Array |
| 06/12/2008 | US20080139408 Nucleic acid amplifier and method of nucleic acid amplification |
| 06/12/2008 | US20080139407 Segment synthesis |
| 06/12/2008 | US20080139405 Colloidal compositions for solid phase biomolecular analytical, preparative and identification systems |
| 06/12/2008 | US20080139402 Cell-based detection and differentiation of disease states |
| 06/12/2008 | US20080139395 Microarray and Spotting Apparatus |
| 06/12/2008 | CA2671553A1 Ob-fold used as scaffold for engineering new specific binders |
| 06/11/2008 | EP1444235B1 Reverse-turn mimetics and method relating thereto |
| 06/11/2008 | EP1276857B1 Signal sequence trapping |
| 06/10/2008 | US7384388 Styryl dyes with linker |
| 06/05/2008 | US20080132430 for the purely fluid or light-controlled synthesis or analysis of oligomer or polymeric probes; combinatorial chemistry; DNA, RNA, peptides |
| 06/05/2008 | US20080132429 Biological microarrays with enhanced signal yield |
| 06/05/2008 | US20080132428 Filling multidrop transfer plate with polymerase chain reaction master mix and moving into close proximity with master array for transfering; simple, accurate, low cost |
| 06/05/2008 | CA2671264A1 Improved immunoglobulin libraries |
| 06/03/2008 | US7381571 Multilayer thermoconductive metal substrate with a corrosion resistant plastic coating defining a sample-distribution network having an inlet, detection chambers loaded with detection reagents, and a channel providing a dead-end fluid connection between each chamber and the inlet |
| 06/03/2008 | US7381570 Multilayer thermoconductive metal substrate defining a sample-distribution network having an inlet, detection chambers loaded with reagents, and a channel providing a dead-end fluid connection between each chamber and the inlet; optional temperature-controller |
| 06/03/2008 | US7381569 Device and method for multiple analyte detection |
| 06/03/2008 | US7380441 High throughput screening methods for lubricating oil compositions |
| 05/29/2008 | US20080125332 Methods, Kits and Compositions Pertaining to Combination Oligomers and Libraries for Their Preparation |
| 05/29/2008 | US20080125330 Real-Time Pcr Detection of Microorganisms Using an Integrated Microfluidics Platform |
| 05/29/2008 | US20080124277 Human and Mouse Targeting Peptides Identified by Phage Display |
| 05/22/2008 | US20080119373 Receptor Specific Binder Discovery Using Intramolecular Acyl Migration Induced Dynamic Carbohydrate Library |
| 05/22/2008 | US20080119372 Microarray and Method of Fabricating the Same |
| 05/22/2008 | US20080119370 Porous substrate plates and the use thereof |
| 05/15/2008 | WO2007089382A3 Nanofactory compositions and methods of making and using nanofactories |
| 05/15/2008 | US20080113876 Probe array and associated methods |
| 05/15/2008 | US20080113872 Classification of Organisms Based on Genome Representing Arrays |
| 05/13/2008 | CA2370535C Replica amplification of nucleic acid arrays |
| 05/08/2008 | WO2008052358A1 Microfluidic device having an array of spots |
| 05/08/2008 | US20080108515 Arrayed polynucleotides |
| 05/08/2008 | US20080108513 Cellular Arrays |
| 05/08/2008 | US20080108512 Method For The Site-Specific Synthesis Of Biopolymers On Solid Supports |
| 05/08/2008 | US20080108507 Method for in vitro molecular evolution of protein function |
| 05/08/2008 | US20080108082 Polymerase enzymes and reagents for enhanced nucleic acid sequencing |
| 05/08/2008 | US20080108068 Device and method for multiple analyte detection |
| 05/08/2008 | US20080108058 Using interferon expression profile as diagnostic tool in deetction of autoimmune diseases |
| 05/08/2008 | CA2666378A1 Microfluidic device having an array of spots |
| 05/06/2008 | US7367933 Screening of chemical compounds purified from biological sources |
| 05/06/2008 | CA2163637C Topologically segregated, encoded solid phase libraries |
| 05/02/2008 | WO2008051530A2 Polymerase enzymes and reagents for enhanced nucleic acid sequencing |
| 05/02/2008 | WO2008049795A1 Method and system for calibrating laser focus and position in micro-arrays |
| 05/01/2008 | US20080103063 Quality Assurance/Quality Control for High Throughput Bioassay Process |
| 05/01/2008 | US20080103062 Acoustically mediated fluid transfer methods and uses thereof |
| 05/01/2008 | US20080102462 Device and method for multiple analyte detection |
| 05/01/2008 | US20080102461 Device and method for multiple analyte detection |
| 04/29/2008 | US7364697 Apparatus comprising infrared camera for rapidly screening arrays of diverse materials on single substrate surfaces; combinatorial synthesis and characterization of libraries of diverse materials |
| 04/29/2008 | CA2254833C Pharmaceutical for treatment of neurological and neuropsychiatric disorders |
| 04/24/2008 | US20080096771 Methods, Systems and Computer Software For Designing and Synthesizing Sequence Arrays |
| 04/10/2008 | WO2008041693A1 Tool for screening of plant having useful trait and use thereof |
| 04/10/2008 | US20080085840 sequencing a nucleic acid comprising stabilizing a primer/target nucleic acid duplex on a substrate. Methods of the invention generally contemplate the use of a dual-anchored primer/target nucleic acid duplex, or a stabilizing molecule in a single molecule sequencing reaction. |
| 04/10/2008 | US20080085839 determining point mutations by means of DNA microarrays and TIRF excitation. According to said method, bonding of nucleic acids to short DNA probes on a microarray is measured at different temperatures. Melting point curves are generated from the measured values |
| 04/10/2008 | CA2664681A1 Design and construction of diverse synthetic peptide and polypeptide libraries |
| 04/09/2008 | EP1908513A1 Method for preparing and using chemical collections |
| 04/09/2008 | EP1299532B1 Improved combinatorial libraries by recombination in yeast and analysis method |
| 04/03/2008 | US20080081768 Methods of constructing and screening libraries of peptide structures |
| 04/03/2008 | US20080081074 Polymers for functional particles |
| 04/02/2008 | EP1508042A4 Biochips with surfaces coated with polysaccharide based hydrogels |
| 03/27/2008 | WO2007038829A8 Method of drug design |
| 03/27/2008 | US20080076679 Systems and methods of combinatorial synthesis using laser-assisted thermal activation |
| 03/27/2008 | US20080076678 Method of creating a library of bacterial clones with varying levels of gene expression |
| 03/27/2008 | US20080076677 Nucleic acid sample purification and enrichment with a thermo-affinity microfluidic sub-circuit |
| 03/27/2008 | US20080076673 Engineered binding proteins |
| 03/27/2008 | US20080076671 Applications of Nucleic Acid Fragments |
| 03/27/2008 | US20080075739 Attenuated Salmonella SP12 Mutants as Antigen Carriers |
| 03/20/2008 | WO2008032574A1 TRACE mRNA AMPLIFICATION METHOD AND USE THEREOF |
| 03/20/2008 | US20080070804 Synthetic substrates and inhibitors with enhanced specificity |
| 03/20/2008 | US20080070803 Electrochemical Treatment Of Substrates |
| 03/20/2008 | US20080070802 Directed heterobifunctional linkers |
| 03/20/2008 | US20080070801 Production of nano-powder based combinatorial libraries |
| 03/20/2008 | CA2662931A1 Trace mrna amplification method and use thereof |
| 03/19/2008 | EP1899465A2 Iterated branching reaction pathways via nucleic acid-mediated chemistry |
| 03/18/2008 | US7344714 Generation preferential antibody; construct peptide library, immunize cells, isolating and purify antisera from cells |
| 03/18/2008 | CA2425634C Method and device for creating micro-arrays |
| 03/13/2008 | US20080064610 Selecting a scaffold polypeptide, possible substitutions, excluding those that express unfavorable phenotypes or genotypes; pure affinity reagents, therapeutic proteins, or designer enzymes |
| 03/13/2008 | US20080064606 Selectively binds with absolute control over orientation and density without requiring prior synthetic modification or purification to make a stable protein chip; rapid and irreversible; assaying kinase or protease activity |
| 03/12/2008 | CN100374956C A composition containing a photoacid generator monomer and carrier coated with the same and application thereof |
| 03/06/2008 | US20080058225 Efficient, specific and sensitive targeted synthesis; utilizing spatial resolution of microarrays and exponential power of combinatorial display; forming spots on solid support and immobilizing by covalent coupling and/or ionic interaction |
| 03/06/2008 | US20080058224 Substrate chemistry for protein immobilization on a rigid support |
| 03/06/2008 | US20080058223 Passaged neural stem cell-derived neuronal networks as sensing elements for detection of environmental threats |
| 03/06/2008 | US20080058222 Obtaining faithful RNA and cDNA expression libraries; extraction from intact tissue cultured in three dimensional sponge gels; tumor development prognosis |
| 03/06/2008 | US20080058217 Producing libraries; including high salt post translational incubation step |
| 03/06/2008 | US20080058215 Internal control molecule; determining optimal spotting concentrations of immunoglobulin G; increasing detectable signal |
| 03/06/2008 | DE102006039479A1 Programmierbare Oligonukleotidsynthese Programmable oligonucleotide synthesis |
| 02/28/2008 | WO2008024909A2 Directed heterobifunctional linkers |
| 02/28/2008 | WO2008022469A1 2'-DEOXY-2'-FLUORO-β-D-ARABINONUCLEOSIDE 5'-TRIPHOSPHATES AND THEIR USE IN ENZYMATIC NUCLEIC ACID SYNTHESIS |
| 02/28/2008 | US20080051298 Microarrays including probe cells formed within substrates and methods of making the same |
| 02/28/2008 | US20080050370 Stabilized polypeptide compositions |
| 02/28/2008 | CA2661640A1 Mapping of genomic interactions |
| 02/20/2008 | CN101126176A Preparation method for PCR high flux construction siRNA whole site molecule library |
| 02/19/2008 | US7331920 Glycopeptide antibiotics, combinational libraries of glycopeptide antibiotics and methods of producing same |
| 02/14/2008 | US20080039343 Randomly Ordered Arrays and Methods of Making and Using |
| 02/14/2008 | US20080038718 Method For Parallelly Sequencing A Nucleic Acid Mixture By Using a Continuous Flow System |
| 02/12/2008 | CA2090485C Method and apparatus for the rapid synthesis of substrate-bound or free peptides or oligonucleotides, flat material synthesized in this way and the use of such material |
| 02/07/2008 | US20080033706 Design and selection of genetic targets for sequence resolved organism detection and identification |
| 02/06/2008 | EP1534735A4 Coded nucleic acid carriers |