Patents for C40B 40 - Libraries per se, e.g. arrays, mixtures (17,361)
01/1995
01/12/1995WO1995001559A2 Sample holder and its use
01/10/1995US5380495 Solid phase peptide synthesizer
01/05/1995WO1995000530A1 Hybridization and sequencing of nucleic acids
01/04/1995EP0631633A1 Reaction-based selection for expression of and concentration of catalytic moieties
12/1994
12/22/1994WO1994029719A1 Random generation and bio-specific selection of chemical compounds
12/21/1994EP0624059A4 Combinatorial strategies for polymer synthesis.
12/08/1994WO1994028424A1 Method for selection of biologically active peptide sequences
12/08/1994WO1994028145A2 Expression of urokinase plasminogen activator inhibitors
12/08/1994WO1994027719A1 Method and apparatus for conducting an array of chemical reactions on a support surface
12/08/1994CA2163620A1 Method for selection of biologically active peptide sequences
12/08/1994CA2162855A1 Expression of urokinase plasminogen activator inhibitors
12/07/1994EP0627488A1 Method for producing filamentous phages displaying on the surface of the capsid peptides capable of binding biotin, and filamentous phages and peptides thus obtained
11/1994
11/30/1994EP0349578B1 Organism carrying a Single Chain Antibody Domain at its surface.
11/30/1994CN1095759A In situ PCR amplification system
11/29/1994US5368823 Automated synthesis of oligonucleotides
11/24/1994WO1994026886A2 Process for the preparation of immunogens or diagnostic reagents, and immunogens or diagnostic reagents thereby obtainable
11/24/1994WO1994026787A1 Method for generating cell type specific phage antibody libraries
11/24/1994WO1994026775A1 Linear substituted oligoalkyleneimine libraries
11/17/1994EP0624059A1 Combinatorial strategies for polymer synthesis
11/15/1994US5364790 In situ PCR amplification system
11/15/1994US5364591 Device for moving a target-bearing solid through a liquid for detection while being contained
11/15/1994US5364068 Valve block assembly
11/09/1994EP0623626A1 Automated allyl deprotection in solid-phase synthesis
11/08/1994US5362447 Automated peptide synthesizer
10/1994
10/27/1994WO1994024278A1 Selecting genes encoding catalytic antibodies
10/18/1994US5356797 Membrane expression of heterologous genes
10/18/1994US5356596 Apparatus for isolation of synthetic peptide without mechanical loss
10/12/1994EP0619321A1 Very large scale immobilized peptide synthesis
10/05/1994EP0574511B1 Method and device for heterogeneous phase synthesis of macromolecules such as peptides, polynucleotides or oligosaccharides
09/1994
09/30/1994WO1993019172A1 Methods for producing members of specific binding pairs
09/30/1994CA2131151A1 Methods for producing members of specific binding pairs
09/20/1994US5348867 Expression of proteins on bacterial surface
09/15/1994WO1994020521A1 Process for synthesizing and selecting sequences of covalently bound components
09/15/1994DE4308410A1 Process for the synthesis and selection of sequences composed of covalently linked building blocks
09/14/1994EP0614989A1 A method for in vivo selection of ligand-binding proteins
09/07/1994EP0613400A1 Test device comprising a plate containing a multiplicity of wells with an associated metering device, as well as a kit which comprises these devices and use of the devices.
09/06/1994US5344613 Prevents splashing, agglomeration
09/01/1994WO1994019694A1 Thin film hpmp matrix systems and methods for constructing and displaying ligands
09/01/1994DE4406491A1 Cleavage apparatus
08/1994
08/31/1994EP0476014B1 Very large scale immobilized polymer synthesis
08/31/1994EP0373203B1 Method and apparatus for analysing polynucleotide sequences
08/30/1994US5342585 Apparatus for making multiple synthesis of peptides on solid support
08/24/1994EP0611598A2 In situ PCR amplification system
08/18/1994WO1994018318A1 Totally synthetic affinity reagents
08/18/1994WO1994018226A1 Automated synthesis of oligonucleotides
08/18/1994WO1994018221A1 Methods for producing polypeptide binding sites
08/18/1994WO1994018220A1 Methods for producing polypeptide metal binding sites and compositions thereof
08/18/1994WO1994018219A1 Methods for producing antibody libraries using universal or randomized immunoglobulin light chains
08/18/1994WO1994018218A1 Methods and apparatus for dna sequencing
08/18/1994DE4403967A1 Process and apparatus for simultaneous multiple solid-phase synthesis
08/18/1994CA2155186A1 Methods and apparatus for dna sequencing
08/18/1994CA2115811A1 A method for in vivo selection of ligand-binding proteins
08/17/1994CA2106360A1 In situ pcr amplification system
08/16/1994US5338831 Anchoring amino acid to inert porous material in compartments of carrier disk, dispensing measured quantity of reactant to each by rotating disk, while common synthesis steps proceed in all compartments at same time
08/03/1994EP0608779A1 Apparatus for peptide synthesis
08/02/1994US5333675 Apparatus and method for performing automated amplification of nucleic acid sequences and assays using heating and cooling steps
07/1994
07/13/1994EP0605522A1 Production of chimeric antibodies - a combinatorial approach
07/07/1994WO1994014972A1 Method and apparatus for enzymatic synthesis of oligonucleotides
07/07/1994CA2150670A1 Method and apparatus for enzymatic synthesis of oligonucleotides
07/06/1994EP0604552A1 Method of synthesizing diverse collections of oligomers.
06/1994
06/29/1994EP0603672A2 Process for the production of recombinant and synthetic peptides and their use
06/28/1994US5324633 Exposing immobilized polymers to a fluorescently-labelled receptor in solutions of varying concentration
06/28/1994US5324483 Apparatus for multiple simultaneous synthesis
06/24/1994CA2112193A1 Process for preparing recombinant and synthetic peptides, and their use
06/23/1994WO1994013804A1 Multivalent and multispecific binding proteins, their manufacture and use
06/15/1994EP0600866A1 Compositions and methods for identifying biologically active molecules
06/07/1994US5318679 Photoprotected amines attached to support surface are selectively irradiated to deprotect preselected area so that support surface are subjected to chemical reaction to link aminoacids to the selectively deprotected area
05/1994
05/31/1994US5316954 Chemical reactors with multicompartment tubes and means for detaching, coupling and joining
05/31/1994US5316922 Binding proteins, ligation polynucleotides and insertion gene coding
05/31/1994US5316034 For dispensing reactive fluids
05/26/1994WO1994011530A1 Positional sequencing by hybridization
05/26/1994WO1994011496A1 Soluble peptides having constrained, secondary conformation in solution and method of making same
05/26/1994WO1994011388A1 Support for the synthesis of modular polymers
05/26/1994CA2148838A1 Soluble peptides having constrained, secondary conformation in solution and method of making same
05/26/1994CA2148591A1 Support for the synthesis of modular polymers
05/11/1994EP0558671A4 Synthesis of equimolar multiple oligomer mixtures, especially of oligopeptide mixtures
05/11/1994EP0516672B1 Process and device for the simultaneous synthesis of several polypeptides
05/11/1994EP0344177B1 Porous wafer for segmented synthesis of biopolymers
04/1994
04/28/1994WO1994008759A1 Method and apparatus for robotically performing sanger dideoxynucleotide dna sequencing reactions
04/28/1994WO1994008711A1 Apparatus and method for multiple simultaneous synthesis
04/27/1994EP0593422A1 Method of synthesizing oligonucleotides adaptable to large scale syntheses.
04/20/1994EP0592968A1 Automated peptide synthesizer
04/19/1994US5304487 Device for analyzing fluid cell-containing sample consisting of solid substrate with inlet port, flow channel, cell handling region with lysing structure, detection system
04/06/1994EP0590057A1 MIMIC PEPTIDES OF gp120
03/1994
03/31/1994WO1994006920A1 Recombinant viruses displaying a nonviral polypeptide on their external surface
03/31/1994CA2145063A1 Recombinant viruses displaying a nonviral polypeptide on their external surface
03/29/1994US5298259 Subunit delivery composition and method
03/22/1994US5296375 Mesoscale sperm handling devices
03/17/1994WO1994005781A1 Phagemids coexpressing a surface receptor and a surface heterologous protein
03/17/1994WO1994005394A1 Specification method and apparatus for peptide synthesis and screening
03/17/1994WO1993025912A3 Automated preparation of nucleic acids
03/16/1994EP0586600A1 Parallel sequential reactor.
03/10/1994DE4230089A1 A laboratory robot for automated processing of proteins - uses a filtration aid, e.g. diatomite, after peptide pptn., and is useful for the parallel purificn. of several peptide(s)
03/09/1994EP0585287A1 Methods for producing members of specific binding pairs
03/03/1994WO1993022055A3 Fluid handling in microfabricated analytical devices
02/1994
02/22/1994US5288644 High speed, automatic detection of mass weights of DNA fragments; mass spectrometry
02/22/1994US5288468 Parallel sequential reactor
02/22/1994US5288464 Peptide synthesis
02/15/1994US5286789 Solid phase multiple peptide synthesis
02/03/1994WO1993022678A3 Optical and electrical methods and apparatus for molecule detection