Patents for C40B 40 - Libraries per se, e.g. arrays, mixtures (17,361)
06/1999
06/03/1999WO1999026902A1 A solid-phase technology for the preparation of combinatorial libraries through amide-bond anchoring
06/03/1999CA2311490A1 A solid-phase technology for the preparation of combinatorial libraries through amide-bond anchoring
06/02/1999EP0918885A1 Nanoparticles having oligonucleotides attached thereto and uses therefor
06/02/1999EP0918845A1 Cleavable signal element device and method
06/02/1999EP0918786A1 Nuclease protection assays
05/1999
05/27/1999WO1999025818A1 Method of identifying binding site domains that retain the capacity of binding to an epitope
05/27/1999WO1999025724A2 Oligonucleotide synthesis using high boiling point solvents
05/27/1999WO1999019711B1 Method for producing arrays and devices relating thereto
05/27/1999WO1999005308A3 Apparatus and methods for arraying solution onto a solid support
05/27/1999CA2309927A1 Oligonucleotide synthesis using high boiling point solvents
05/26/1999EP0917494A1 Systems and methods for the combinatorial synthesis of novel materials
05/26/1999EP0804731B1 Method and apparatus for fabricating microarrays of biological samples
05/20/1999WO1999024822A1 Rapid screening assay methods and devices
05/20/1999WO1999024645A1 Array of functionalized micro-electrodes
05/20/1999WO1999024458A1 Carrier-reporter bead assemblies
05/20/1999WO1999010494A3 Agonist antibodies to the thrombopoietin receptor, and their therapeutic uses
05/20/1999CA2310267A1 Rapid screening assay methods and devices
05/19/1999EP0916397A2 Apparatus and method used in multiple, simultaneous synthesis of general compounds
05/19/1999EP0916396A2 Combinatorial strategies for polymer synthesis
05/19/1999EP0915897A1 Process for combining parallel oligonucleotide synthesis and preparation of oligomer chips
05/19/1999EP0675760B1 Method and apparatus for creating biopolymer arrays on a solid support surface
05/18/1999US5905024 Method for performing site-specific affinity fractionation for use in DNA sequencing
05/14/1999CA2253164A1 Apparatus and method used in multiple, simultaneous synthesis of general compounds
05/11/1999US5902723 Selectively removing a nucleotide by cleavage at terminal ends with catalytic antibodies; identifying excision site and repeating process; for concurrent parallel sequence analysis
05/06/1999WO1999022010A1 Methods for identifying nucleic acid sequences and (poly)peptides which increase the expression yields of functional periplasmic proteins
05/06/1999EP0913485A1 Method and apparatus for fabricating microarrays of biological samples
05/06/1999EP0912728A1 Novel synthetic protein structural templates for the generation, screening and evolution of functional molecular surfaces
05/06/1999CA2305631A1 Methods for identifying nucleic acid sequences and (poly)peptides which increase the expression yields of functional periplasmic proteins
05/05/1999CN1215995A Reactor and method for solid phase peptide synthesis
05/04/1999US5901069 System, method, and computer program product for at least partially automatically generating chemical compounds with desired properties from a list of potential chemical compounds to synthesize
05/04/1999US5900481 Bead linkers for immobilizing nucleic acids to solid supports
04/1999
04/29/1999WO1999020749A1 Method to screen phage display libraries with different ligands
04/29/1999WO1999007888A9 Surface-bound, bimolecular, double-stranded dna arrays
04/29/1999WO1998049286A9 Directed evolution of enzymes and antibodies
04/28/1999EP0911396A2 Methods for generating polynucleotides having desired characteristics by iterative selective and recombination
04/28/1999EP0910670A1 Covalent attachment of nucleic acid molecules onto solid-phases via disulfide bonds
04/28/1999EP0910467A1 Electrochemical solid phase synthesis of polymers
04/28/1999EP0876509A4 Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
04/27/1999US5897838 Apparatus for rapid evaporation of aqueous solutions
04/22/1999WO1999019724A1 Radiation activation and screening of catalyst libraries for catalyst evaluation and reactors therefor
04/22/1999WO1999019711A1 Method for producing arrays and devices relating thereto
04/22/1999WO1999019344A1 Coding combinatorial libraries with fluorine tags
04/22/1999WO1998058745A9 Electrospraying solutions of substances for mass fabrication of chips and libraries
04/22/1999WO1998021221A3 1-thiogalactose derivatives
04/22/1999CA2306970A1 Method for producing arrays and devices relating thereto
04/22/1999CA2306256A1 Radiation activation and screening of catalyst libraries for catalyst evaluation and reactors therefor
04/22/1999CA2305771A1 Coding combinatorial libraries with fluorine tags
04/21/1999EP0909176A1 Reactor and method for solid phase peptide synthesis
04/15/1999WO1998059360A9 Retentate chromatography and protein chip arrays with applications in biology and medicine
04/15/1999WO1998047343A9 Antibodies or binding protein libraries displayed on phage, cells, or other replicatable genetic packages
04/14/1999EP0907887A1 Engineering affinity ligands for macromolecules
04/14/1999EP0907625A1 Fluorous reaction and separation systems
04/13/1999US5894068 Reduction of NOx in the exhaust gases from internal combustion engines containing excess oxygen
04/07/1999EP0906418A1 Methods and compositions for cellular and metabolic engineering
04/06/1999US5891648 Reaction-based selection for expression of and concentration of catalytic moieties
04/06/1999US5891630 Identifying molecular structures within a sample substance using an array having a plurality of test sites upon which the sample substance is applied.
04/01/1999WO1999015897A1 Subtractive protein screening for gene identification
03/1999
03/31/1999EP0904541A1 PURIFICATION OF TISSUE PLASMINOGEN ACTIVATOR (tPA)
03/31/1999EP0904540A1 Methods for spatially-dispersed positionally-encoded combinatorial library synthesis
03/30/1999US5889165 Photolabile nucleoside protecting groups
03/25/1999WO1999014318A1 Method for the complete chemical synthesis and assembly of genes and genomes
03/25/1999WO1998051819A9 Methods for electronic fluorescent perturbation for analysis and electronic perturbation catalysis for synthesis
03/25/1999WO1998049286A3 Directed evolution of enzymes and antibodies
03/24/1999EP0739413B1 Method of selecting specific bacteriophages
03/23/1999US5885837 Very large scale immobilized polymer synthesis using mechanically directed flow paths
03/23/1999US5885793 Production of anti-self antibodies from antibody segment repertoires and displayed on phage
03/23/1999US5885780 Method of obtaining small conformationally rigid conopeptides
03/23/1999US5885577 Possess binding specificities that are similar to the binding specificities of the antibodies or receptors; may be used in place of antibodies in many assays or therapeutic applications
03/18/1999WO1999013313A1 Method of making high density arrays
03/17/1999EP0902034A2 Very large scale immobilized peptide synthesis
03/11/1999WO1999011777A1 Methods for protein screening
03/11/1999WO1999011754A1 Dna capillary
03/11/1999WO1999011654A1 Randomly generated glycopeptide combinatorial libraries
03/11/1999CA2302472A1 Randomly generated glycopeptide combinatorial libraries
03/04/1999WO1999010494A2 Agonist antibodies to the thrombopoietin receptor, and their therapeutic uses
03/04/1999WO1999010485A1 Methods using phage display for selecting internalizing ligands for gene delivery
03/04/1999WO1999010321A2 Antimicrobial compounds
03/04/1999WO1999010014A2 Receptor-mediated gene delivery using bacteriophage vectors
03/04/1999WO1998056915A3 Artificial antibody polypeptides
03/04/1999CA2302293A1 Receptor-mediated gene delivery using bacteriophage vectors
03/04/1999CA2302292A1 Methods using phage display for selecting internalizing ligands for gene delivery
03/03/1999EP0898575A2 A combinatorial protecting group strategy for multifunctional molecules
03/03/1999EP0797683A4 Methods and apparatus for dna sequencing and dna identification
03/02/1999US5876925 Generating bacteriophage display library expressing heterologous protein which bonds antigen on magnetically labeled cells; incubating with labeled and unlabeled cells, separating out label cells, isolating dna
02/1999
02/25/1999WO1999009394A1 Apparatus for performing assays at reaction sites
02/25/1999WO1999009217A1 Methods and compositions for detection or quantification of nucleic acid species
02/25/1999WO1998032017A3 Modulators of insulin receptor activity
02/25/1999CA2301095A1 Apparatus for performing assays at reaction sites
02/25/1999CA2300940A1 Methods and compositions for detection or quantification of nucleic acid species
02/23/1999US5874554 Dispensing a mixture of acetonitrile with a stabilizing co-solvent which is an organic solvent having a boiling point or flash point greater than about 100.degree. c., and is miscible with acetonitrile
02/23/1999US5874532 Method for solution phase synthesis of oligonucleotides and peptides
02/23/1999US5874219 Methods for concurrently processing multiple biological chip assays
02/23/1999US5874214 Useful for identification, tracking and categorization of components of complex mixtures of diverse molecules; drug delivery
02/18/1999WO1999007888A1 Surface-bound, bimolecular, double-stranded dna arrays
02/18/1999WO1999007842A1 Materials and methods for selecting phage displaying ligand binders
02/16/1999US5872209 Artificial recombinant substrate (rAGG 1) and native aggrecan to determine the proteolytic activity of `aggrecanase` in cell culture systems
02/16/1999US5872015 Molecular diversity screening method
02/16/1999US5871974 Recombinant expression of heteromeric receptors on the surface of filamentous bacteriophage
02/16/1999US5871928 Methods for nucleic acid analysis
02/16/1999US5871907 Methods for producing members of specific binding pairs