Patents for C40B 40 - Libraries per se, e.g. arrays, mixtures (17,361)
02/1994
02/02/1994EP0580737A1 Heterodimeric receptor libraries using phagemids
01/1994
01/20/1994WO1994001215A1 Fluid delivery system utilizing multiple port valve
01/20/1994WO1994001214A1 On-line process flow and reaction monitor
01/20/1994WO1994001213A1 Synthesis reaction column
01/06/1994WO1994000471A1 Trityl monitor for automated polynucleotide synthesis
12/1993
12/29/1993EP0575485A1 Process for the development of binding mini-proteins
12/28/1993US5273718 Applying gas pressure to the wells of a microtiter plate; and an inflatable collar for sealing
12/28/1993US5273715 Automated system for providing a sequence of chemicals to a reaction process
12/28/1993US5273656 System for solid phase reactions
12/23/1993WO1993025912A2 Automated preparation of nucleic acids
12/23/1993WO1993025709A1 Preparation of nucleic acids
12/21/1993US5272075 System for solid phase reactions
12/15/1993EP0573611A1 Improved epitode displaying phage
12/15/1993EP0573603A1 Inhibitors of human neutrophil elastase and human cathepsin g
12/14/1993US5270183 Polymerase chain reaction to amplify DNA
12/09/1993WO1993024625A1 Gene macromolecule reaction method and apparatus therefor
12/08/1993EP0573098A2 Device and method for providing confined reaction and detection
12/08/1993EP0572433A1 Antigen-presenting capsid with fusion ms2-coat protein
11/1993
11/16/1993US5262530 Solid phase synthesis on polystyrene support, phosphoramidite chemistry
11/11/1993WO1993022680A1 Spatially-addressable immobilization of oligonucleotides and other biological polymers on surfaces
11/11/1993WO1993022678A2 Optical and electrical methods and apparatus for molecule detection
11/11/1993WO1993022480A1 Electrochemical treatment of surfaces
11/11/1993WO1993022421A1 Microfabricated sperm handling devices
11/11/1993WO1993022058A1 Polynucleotide amplification analysis using a microfabricated device
11/11/1993WO1993022055A2 Fluid handling in microfabricated analytical devices
11/11/1993WO1993022054A1 Analysis based on flow restriction
11/11/1993WO1993022053A1 Microfabricated detection structures
11/11/1993WO1993018163A3 Delivery and expression of a hybrid surface protein on the surface of gram positive bacteria
11/02/1993US5258289 Specific cleavage of immunoglobulin E class peptides, allergy treatment
10/1993
10/27/1993EP0431059B1 A method for carrying out organic chemical reactions and apparatus for carrying out that method
10/14/1993WO1993020130A1 Apparatus for processing biopolymer-containing columns
10/14/1993WO1993020096A1 Oligonucleotide libraries useful for producing primers
10/13/1993EP0564531A1 Enrichment method for variant proteins with altered binding properties
10/12/1993US5252743 Using cage binding compound
10/12/1993US5252296 Method and apparatus for biopolymer synthesis
10/05/1993CA1322745C Porous wafer for segmented synthesis of biopolymers
09/1993
09/29/1993EP0562047A1 Sequencing by hybridization of a target nucleic acid to a matrix of defined oligonucleotides
09/29/1993EP0562025A1 Very large scale immobilized polymer synthesis
09/16/1993WO1993018163A2 Delivery and expression of a hybrid surface protein on the surface of gram positive bacteria
09/16/1993WO1993017785A1 Device for simultaneously or successively carrying out chemical reactions
09/16/1993DE4206488A1 Vorrichtung zur durchfuehrung zeitgleich oder sequentiell ablaufender chemischer reaktionen Apparatus for carrying out simultaneously or sequentially occurring chemical reactions
09/16/1993CA2131995A1 Delivery and expression of a hybrid surface protein on the surface of gram positive bacteria
09/08/1993EP0558671A1 Synthesis of equimolar multiple oligomer mixtures, especially of oligopeptide mixtures
09/07/1993US5243540 Computer-driven amino acid indexer for peptide synthesis
09/07/1993US5242974 Polymer reversal on solid surfaces
09/02/1993WO1993017126A1 Novel oligonucleotide arrays and their use for sorting, isolating, sequencing, and manipulating nucleic acids
09/02/1993WO1993017124A1 Reaction-based selection for expression of and concentration of catalytic moieties
09/02/1993CA2130562A1 Novel oligonucleotide arrays and their use for sorting, isolating, sequencing, and manipulating nucleic acids
09/02/1993CA2125405A1 Reaction-based selection for expression of and concentration of catalytic moieties
09/01/1993EP0558050A1 Apparatus and method for isolation of synthetic peptide without loss of reagents
09/01/1993EP0557897A1 Antigen binding proteins and methods for their production
08/1993
08/31/1993US5240680 Automated apparatus for use in peptide synthesis
08/29/1993CA2089966A1 Antigen binding proteins and methods for their production
08/18/1993EP0555706A1 Agitation stabilizer in solidphase peptide synthesizer
08/11/1993EP0535242A4 Method and device for determining nucleotide sequence of dna
08/02/1993EP0604552A4 Method of synthesizing diverse collections of oligomers.
07/1993
07/27/1993US5231029 Spraying, incubation
07/21/1993EP0551438A1 Surface expression libraries of randomized peptides
07/14/1993EP0550645A1 Surface expression libraries of heteromeric receptors
06/1993
06/29/1993US5223409 Directed evolution of novel binding proteins
06/29/1993US5223408 Method for making variant secreted proteins with altered properties
06/24/1993WO1993012427A1 Automated apparatus for use in peptide synthesis
06/23/1993EP0547201A1 Phagemide for screening antibodies
06/23/1993EP0547200A1 Recombinant antibodies at the surface of e. coli
06/16/1993EP0546393A1 Peptide synthesizer
06/10/1993WO1993011236A1 Production of anti-self antibodies from antibody segment repertoires and displayed on phage
06/02/1993EP0239600B1 Apparatus for, and methods of, operating upon a fluid
05/1993
05/27/1993WO1993010214A1 Expression of proteins on bacterial surface
05/27/1993WO1993010161A1 Polymer reversal on solid surfaces
05/27/1993WO1993009872A1 Test device comprising a plate containing a multiplicity of wells with an associated metering device, as well as a kit which comprises these devices and use of the devices
05/27/1993WO1993009668A1 Combinatorial strategies for polymer synthesis
05/27/1993CA2123801A1 Test device comprising a plate containing a multiplicity of wells with an associated metering device, as well as a kit which comprises these devices and use of the devices
05/27/1993CA2123676A1 Expression of proteins on bacterial surface
05/26/1993EP0543550A1 Method and apparatus for molecule detection
05/26/1993EP0542770A1 Random bio-oligomer library, a method of synthesis thereof, and a method of use thereof
05/12/1993EP0541340A2 Biopolymer synthesis apparatus and method
05/05/1993EP0502060A4 Spatially-addressable immobilization of anti-ligands on surfaces
04/1993
04/29/1993CA2121807A1 Method and apparatus for controlling liquid level in a knot drainer
04/20/1993US5204455 Oligonucleotides having internal phosphonate linkages from a fast and efficient solid phase synthesis
04/20/1993US5203368 Matrix of valves
04/13/1993US5202418 Method of performing multiple synthesis of peptides on solid carrier
04/07/1993EP0535242A1 Method and device for determining nucleotide sequence of dna
04/07/1993EP0535151A1 Peptide library and screening systems
04/01/1993WO1993006213A1 Production of chimeric antibodies - a combinatorial approach
04/01/1993WO1993006121A1 Method of synthesizing diverse collections of oligomers
04/01/1993CA2118806A1 Method of synthesizing diverse collections of oligomers
03/1993
03/31/1993EP0498801A4 Solid surface for peptide synthesis
03/30/1993US5198346 Generation and selection of novel DNA-binding proteins and polypeptides
03/18/1993WO1993004756A1 System for solid phase reactions
03/18/1993CA2116360A1 System for solid phase reactions
03/03/1993EP0529573A1 Solid-phase synthesizer
03/03/1993EP0529504A2 Apparatus for the simultaneous synthesy of different peptides
02/1993
02/24/1993EP0527839A1 Recombinant library screening methods
02/23/1993US5188733 Apparatus and process for effecting sequential peptide syntheses
02/23/1993US5188148 Conduit plate for fluid delivery system
02/18/1993WO1993002992A1 Synthesis of chain chemical compounds
02/17/1993EP0527149A1 Methods and apparatus allowing sequential chemical reactions.
02/16/1993US5186898 Single coupling
02/16/1993US5186824 Rotating processor; sequential separation by fluid density
02/10/1993EP0526691A2 Apparatus for carrying out chemical processes on a sample of chemical material