Patents for C40B 40 - Libraries per se, e.g. arrays, mixtures (17,361)
12/1997
12/04/1997WO1997045538A1 Novel synthetic protein structural templates for the generation, screening and evolution of functional molecular surfaces
12/04/1997WO1997045115A1 Pharmaceutical for treatment of neurological and neuropsychiatric disorders
12/04/1997WO1997041139A3 A combinatorial protecting group strategy for multifunctional molecules
12/04/1997CA2619901A1 Pharmaceutical for treatment of neurological and neuropsychiatric disorders
12/03/1997EP0600866B1 Compositions and methods for identifying biologically active molecules
11/1997
11/27/1997WO1997044491A1 Methods of detection utilizing modified bacteriophage
11/26/1997EP0808456A1 A partitioned microelectronic device array
11/20/1997WO1997043641A1 Molecular diversity screening device and method
11/20/1997WO1997043629A1 Electrokinetic pumping
11/20/1997WO1997043450A1 Hybridization assays on oligonucleotide arrays
11/20/1997CA2253755A1 Electrokinetic pumping
11/18/1997US5688696 Combinatorial libraries having a predetermined frequency of each species of test compound
11/18/1997US5688666 Growth hormone variants with altered binding properties
11/18/1997US5688642 Selective attachment of nucleic acid molecules to patterned self-assembled surfaces
11/18/1997US5688474 Oxidation catalysts for exhaust systems for pollution control
11/13/1997WO1997042507A1 Peptide array and method
11/12/1997EP0805877A1 Improved method of selecting specific bacteriophages
11/12/1997EP0734530B1 Combinatorial libraries and methods for their use
11/12/1997CN1164894A Automated molecular biological diagnostic system
11/06/1997WO1997041425A1 Biosensor device and method
11/06/1997WO1997041424A1 Biosensor device and method
11/06/1997WO1997041139A2 A combinatorial protecting group strategy for multifunctional molecules
11/05/1997EP0804731A1 Method and apparatus for fabricating microarrays of biological samples
11/05/1997EP0804281A1 Apparatus and method for multiple synthesis of organic compounds on polymer support
11/04/1997US5684711 System, method, and computer program for at least partially automatically generating chemical compounds having desired properties
11/04/1997US5683899 Methods and compositions for combinatorial-based discovery of new multimeric molecules
10/1997
10/30/1997WO1997040141A2 Isolation of enzymes
10/30/1997CA2548805A1 Light-controlled electrokinetic assembly of particles near surfaces
10/30/1997CA2250922A1 Isolation of enzymes
10/29/1997EP0802983A2 Expression of urokinase plasminogen activator inhibitors
10/28/1997US5681751 Immobilized in a porous matrix; electrophoresis
10/28/1997US5681741 Cover for retaining liquid sample against slide surface during amplification of dna by polymerase chain reaction
10/28/1997US5681534 High throughput oligonucleotide synthesizer
10/28/1997US5681484 Etching to form cross-over, non-intersecting channel networks for use in partitioned microelectronic and fluidic device arrays for clinical diagnostics and chemical synthesis
10/23/1997WO1997039151A1 Photolabile polymer array synthesis methods
10/21/1997US5679773 Reagants and methods for immobilized polymer synthesis and display
10/21/1997US5679548 Inducing mutagenesis of a complementarity determining region (cdr) of an immunoglobulin heavy or light chain gene; amplification of the cdr; genetic engineering
10/15/1997EP0672049A4 Support for the synthesis of modular polymers.
10/14/1997US5677197 Carrier dye in assay spot indicates amount of immobilized reactant present
10/14/1997US5677195 Forming oligonucleotides or peptides by forming flow channels in substrate surface, each of flow channels comprising walls which form fluid-tight seals with surface and a flow intake and outlet, flowing nucleic acids through channels to bind
10/14/1997US5677126 Bonding to nucleic acid
10/08/1997EP0799897A1 Methods and compositions for selecting tag nucleic acids and probe arrays
10/07/1997US5675700 Assembly system for in situ per amplification
10/07/1997US5674743 Cleaving single nucleotide from dna strand; incorporating in fluorescence-enhancing matrix; irradiating; identifying; repeating
10/02/1997WO1997035966A1 Methods and compositions for cellular and metabolic engineering
10/02/1997DE19612356A1 Nucleic acid hybridisation assay
10/01/1997EP0797776A1 Combinatorial libraries having a predetermined frequency of each species of test compound
10/01/1997EP0797683A1 Methods and apparatus for dna sequencing and dna identification
10/01/1997EP0797666A2 Genetically engineered human-derived kunitz domains that inhibit human neutrophil elastase
09/1997
09/25/1997WO1997035198A1 Methods for spatially-dispersed positionally-encoded combinatorial library synthesis
09/25/1997WO1997035197A1 PURIFICATION OF TISSUE PLASMINOGEN ACTIVATOR (tPA)
09/25/1997WO1997035196A1 Engineering affinity ligands for macromolecules
09/25/1997WO1997035194A2 Enantiomeric screening process, and compositions therefor
09/25/1997CA2249419A1 Methods for spatially-dispersed positionally-encoded combinatorial library synthesis
09/23/1997US5670322 Targets, electronic signals and detection of frequency dependent electrical signals
09/16/1997US5667988 Gene expression and genes with antibodies and antigens
09/16/1997US5667667 Electrochemical treatment of surfaces
09/12/1997WO1997033169A1 A method for determining the affinity of proteins for chemical agents during screening of combinatorial libraries
09/12/1997WO1997032892A1 A composite for combinatorial organic synthesis
09/10/1997EP0794001A2 Automated system for polynucleotide synthesis and purification
09/10/1997EP0793718A1 Molecular tagging system
09/09/1997US5665975 Optical detectior including an optical alignment block and method
09/04/1997WO1997032208A1 Catalyst testing process and apparatus
09/04/1997WO1997032017A1 Novel method for the identification of nucleic acid sequences encoding two or more interacting (poly)peptides
09/03/1997EP0792280A1 Method of making a library of compounds
09/03/1997EP0535242B1 Method and device for determining nucleotide sequence of dna
09/02/1997US5663143 Protein which binds and inhibits elastase
09/02/1997US5663062 Oligonucleotide libraries useful for producing primers
09/02/1997US5663046 Directly dividing the contents of each sub-pool into the sub-pools for the next step in the synthetic scheme reduces the calculable error from the that of split synthesis
08/1997
08/28/1997WO1997031256A2 Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays
08/27/1997EP0791238A1 Liquid distribution system
08/26/1997US5660985 Contacting mixture of modified single-stranded nucleic acids with target molecule, partitioning those with increased affinity, amplifying to identify ligands of target molecule
08/21/1997WO1997012680A3 Matrices with memories, sensors with memories and uses thereof
08/20/1997EP0789783A1 Antigen binding peptides (abtides) from peptide libraries
08/20/1997EP0789671A1 The combinatorial synthesis of novel materials
08/19/1997US5658802 Method and apparatus for making miniaturized diagnostic arrays
08/19/1997US5658734 Process for synthesizing chemical compounds
08/19/1997US5658727 Filamentous phage encapsulating genome encoding ligand-binding antibody comprising first and second polypeptides where first polypeptide is fused to carboxy terminal phage membrane anchor domain
08/12/1997US5656741 Process and reagents for processing synthetic oligonucleotides
08/12/1997US5656493 System for automated performance of the polymerase chain reaction
08/07/1997WO1997027940A1 Solid phase synthesizer
08/06/1997EP0787527A1 Solid phase Synthesizer
08/05/1997US5654413 Oligonucleotide tags for specific hybridization
08/05/1997US5653939 Optical and electrical methods and apparatus for molecule detection
07/1997
07/31/1997WO1997027329A1 A rapid method to detect duplex formation in sequencing by hybridization methods
07/31/1997WO1997027324A1 Parallel reaction cassette and associated devices
07/31/1997WO1997006468A3 Pattern formation, replication, fabrication and devices thereby
07/31/1997CA2244120A1 A rapid method to detect duplex formation in sequencing by hybridization methods
07/30/1997EP0786085A1 Method and apparatus for efficient mimotope discovery
07/30/1997EP0703825B1 Method and apparatus for conducting an array of chemical reactions on a support surface
07/29/1997US5651943 Apparatus and method for random polymer synthesis
07/29/1997CA1339097C Performing nucleic acid reactions
07/24/1997WO1997026540A1 Minifiltration method and apparatus
07/24/1997WO1997026539A1 Analytical biochemistry system with robotically carried bioarray
07/24/1997WO1997026300A1 Combinatorial process for preparing substituted indane libraries
07/24/1997WO1997025983A1 Indane derivatives for antipsychotic compositions
07/24/1997CA2243717A1 Indane derivatives for antipsychotic compositions
07/24/1997CA2243500A1 Combinatorial process for preparing substituted indane libraries
07/23/1997EP0785280A2 Polymorphism detection
07/23/1997EP0785274A1 An artifical recombinant substrate (rAGG-1) and native aggrecan to study the proteolytic activity of 'Aggrecanase' in cell culture systems