Patents for C40B 40 - Libraries per se, e.g. arrays, mixtures (17,361)
01/1997
01/14/1997US5594123 Oligonucleotide primers which hybridize with conserved regions of the nucleic acid sequences of the aids virus, for polymerase chain reactions
01/14/1997US5593853 Displacemnt, oligomerization, reduction, alkylation, activation, protection, deprotection, oxidation, alkolation, thiolation, nitrilation, sulfitation, carbanation, fractionation and testing
01/14/1997US5593839 Computer-aided engineering system for design of sequence arrays and lithographic masks
01/14/1997US5593838 Analyzing nucleic acids in samples, positioning and isolation
01/14/1997US5593642 Containment of solid support within a gas dispersion tube
01/09/1997WO1997001098A1 Process for detection, quantification and/or identification of a peptide
01/08/1997EP0752008A1 Dna mutagenesis by random fragmentation and reassembly
01/08/1997CN1139912A Preparation of hydrogen cyanide
01/07/1997US5591646 Method and apparatus for peptide synthesis and screening
01/07/1997US5591604 Recombinant antibodies at the surface of E. coli
01/03/1997WO1997000267A1 Conformationally-restricted combinatorial library composition and method
01/02/1997EP0750629A1 Method and apparatus for performing multiple sequential reactions on a matrix
12/1996
12/27/1996WO1996042004A2 Method and system for inhibiting cross-contamination in fluids of combinatorial chemistry device
12/24/1996US5587128 Polymerase chain reaction
12/19/1996WO1996041180A1 Anchor libraries and identification of peptide binding sequences
12/19/1996WO1996041011A1 Oligonucleotide tags for sorting and identification
12/19/1996WO1996040733A1 A system and method for the modification and purification of peptides
12/19/1996WO1996040201A1 Combinatorial libraries of substrate-bound cyclic organic compounds
12/19/1996CA2332731A1 Oligonucleotide tags for sorting and identification
12/19/1996CA2223183A1 Anchor libraries and identification of peptide binding sequences
12/19/1996CA2221508A1 Combinatorial libraries of substrate-bound cyclic organic compounds
12/17/1996US5585275 Pilot apparatus for peptide synthesis and screening
12/17/1996US5585069 Substrates with wells connected by channels controlled by valves, for concurrent analysis of several liquid samples
12/12/1996WO1996039417A1 Chemical, biochemical and biological processing in thin films
12/12/1996WO1996039260A1 Method of producing micro-electrical conduits
12/12/1996WO1996039252A1 Electrokinetic pumping
12/12/1996CA2223496A1 Chemical, biochemical and biological processing in thin films
12/12/1996CA2223166A1 Method of producing micro-electrical conduits
12/12/1996CA2223099A1 Electrokinetic pumping
12/11/1996EP0746621A1 Expression of proteins on bacterial surface
12/10/1996US5583211 Forming nucleophiles on polypropylene support selected from groups consisting of-nh2,-sh, and -oh; reacting biomonomers
12/10/1996US5582801 Apparatus for multiple simultaneous synthesis
12/04/1996EP0744958A1 Polyclonal antibody libraries
12/03/1996US5580723 Comparing the activities of a segment-substituted polypeptide and the parent polypeptide; borrowing receptor binding properties from functionally divergent hormones
12/03/1996US5580717 Recombinant library screening methods
11/1996
11/27/1996EP0744028A1 Highly specific surfaces for biological reactions, method of preparation and utilization
11/27/1996EP0743988A1 Method for ordering macromolecules by means of a moving meniscus, and uses thereof
11/27/1996EP0743986A1 Heterologous dimeric proteins produced in heterokaryons
11/27/1996EP0743952A1 Generation and screening of synthetic drug libraries
11/27/1996EP0668932A4 Positional sequencing by hybridization.
11/21/1996WO1996036436A1 Remotely programmable matrices with memories and uses thereof
11/21/1996CA2216645A1 Remotely programmable matrices with memories and uses thereof
11/20/1996EP0742837A1 Methods for discovering ligands
11/20/1996EP0742821A1 Method for preparing a multicombinatorial library of antibody gene expression vectors
11/20/1996EP0742781A1 Preparation of hydrogen cyanide
11/19/1996US5576220 Thin film HPMP matrix systems and methods for constructing and displaying ligands
11/14/1996WO1996035781A1 Method of inhibiting the activity of an intracellular constituent
11/14/1996CA2219774A1 Method of inhibiting the activity of an intracellular constituent
11/13/1996EP0589877B1 METHODS FOR PRODUCING FUNCTIONAL, SINGLE-CHAIN Fv ANTIBODY FRAGMENTS ON THE SURFACE OF BACTERIOPHAGE PARTICLES
11/12/1996US5574656 System and method of automatically generating chemical compounds with desired properties
11/06/1996CN1135220A Self-addressable self-assembling microelectronic system and devices for molecular biological analysis and diagnostics
11/05/1996US5571698 Genetic package, chimeric
11/05/1996US5571639 Computer-aided engineering system for design of sequence arrays and lithographic masks
10/1996
10/31/1996WO1996033971A1 Photoactivatable polymers for producing patterned biomolecular assemblies
10/30/1996EP0739980A2 DNA encoding CD 19
10/30/1996EP0739413A1 Method of selecting specific bacteriophages
10/30/1996EP0739349A1 Polymer-supported solution synthesis of oligosaccharides
10/24/1996WO1996020278A3 Genetically engineered human-derived kunitz domains that inhibit human neutrophil elastase
10/23/1996CN1134156A Synthesizing and screening molecular diversity
10/22/1996US5567391 Multicompartment chemical reactors
10/15/1996US5565332 Production of chimeric antibodies - a combinatorial approach
10/15/1996US5565173 Apparatus and method for multiple simultaneous synthesis
10/10/1996WO1996031625A1 Polypeptides having a functional domain of interest and methods of identifying and using same
10/10/1996CA2217641A1 Polypeptides having a functional domain of interest and methods of identifying and using same
10/03/1996WO1996030393A1 A method for the synthesis of mixtures of compounds
10/03/1996WO1996030392A1 Process for the production of combinatorial compound libraries
10/02/1996EP0734530A1 Combinatorial libraries and methods for their use
10/02/1996EP0734397A1 Apparatus and method for polymer synthesis using arrays
09/1996
09/19/1996WO1996028248A1 Disposable reagent storage and delivery cartridge
09/19/1996CA2215417A1 Disposable reagent storage and delivery cartridge
09/18/1996EP0732404A1 Novel expression screening vector
09/18/1996EP0731842A1 Recombinant binding proteins and peptides
09/18/1996EP0731837A1 Bacteria used to produce stable fusion proteins and method for their identification
09/17/1996US5556961 Nucleosides with 5'-O-photolabile protecting groups
09/17/1996US5556762 Scanning synthetic peptide combinatorial libraries: oligopeptide mixture sets having a one predetermined residue at a single, predetermined position, methods of making and using the same
09/17/1996US5556752 Solid supporrt with oligonucleotides, spacers, linking groups and double strands
09/11/1996EP0730663A1 Arrays of nucleic acid probes on biological chips
09/10/1996US5554501 Genetic analysis of patient samples
09/04/1996EP0649341B1 On-line process flow and reaction monitor
09/03/1996US5552270 Methods of DNA sequencing by hybridization based on optimizing concentration of matrix-bound oligonucleotide and device for carrying out same
08/1996
08/28/1996EP0728520A1 Printing molecular library arrays
08/27/1996US5550215 Polymer reversal on solid surfaces
08/27/1996US5549974 Immobilization
08/21/1996EP0727045A1 Self-addressable self-assembling microelectronic systems and devices for molecular biological analysis and diagnostics
08/21/1996EP0726906A1 Synthesizing and screening molecular diversity
08/20/1996US5547839 Contacting polynucleotides with surface of solid substrate, hybridizing using nucleic acid polymerase and labeled nucleotide
08/14/1996EP0725682A1 Microfabricated, flowthrough porous apparatus for discrete detection of binding reactions
08/13/1996US5545531 Methods for making a device for concurrently processing multiple biological chip assays
08/08/1996WO1996024061A1 Methods and apparatus for synthesizing labeled combinatorial chemical libraries
08/08/1996CA2186943A1 Methods and apparatus for synthesizing labeled combinatorial chemical libraries
07/1996
07/31/1996EP0637998B1 Fluid handling in microfabricated analytical devices
07/30/1996US5541314 Method for automated synthesis of oligonucleotides
07/25/1996WO1996022393A1 Improved method of selecting specific bacteriophages
07/25/1996WO1996022157A1 Apparatus and method for multiple synthesis of organic compounds on polymer support
07/25/1996CA2211029A1 Apparatus and method for multiple synthesis of organic compounds on polymer support
07/25/1996CA2210567A1 Improved method of selecting specific bacteriophages
07/24/1996EP0722495A1 A method for displaying proteins
07/23/1996US5538694 Device for simultaneously or sequentially carrying out chemical reactions
07/10/1996EP0721016A2 Nucleic acid library arrays, methods for synthesizing them and methods for sequencing and sample screening using them
07/10/1996EP0586600B1 Parallel sequential reactor