Patents for C40B 40 - Libraries per se, e.g. arrays, mixtures (17,361)
02/1999
02/11/1999WO1999006833A1 Methods for obtaining probes of peptide function
02/11/1999WO1999006587A2 Novel method and phage for the identification of nucleic acid sequences encoding members of a multimeric (poly)peptide complex
02/11/1999WO1999006542A1 Methods for screening bacteriophage libraries
02/11/1999CA2338865A1 Methods for detecting binding events using multiple binding partners and muliple targets
02/11/1999CA2297070A1 Novel method and phage for the identification of nucleic acid sequences encoding members of a multimeric (poly)peptide complex
02/10/1999EP0895592A1 Biosensor device and method
02/10/1999EP0895536A2 Isolation of enzymes
02/09/1999US5869643 Process for preparing polynucleotides on a solid support in a tightly packed bed
02/04/1999WO1999005321A1 Amplification and other enzymatic reactions performed on nucleic acid arrays
02/04/1999WO1999005320A1 Multiple functionalities within an array element and uses thereof
02/04/1999WO1999005308A2 Apparatus and methods for arraying solution onto a solid support
02/04/1999WO1999004896A1 Polyethylenimine-based biomolecule arrays
02/04/1999CA2298017A1 Multiple functionalities within an array element and uses thereof
02/04/1999CA2297681A1 Apparatus and methods for arraying solution onto a solid support
02/04/1999CA2297661A1 Amplification and other enzymatic reactions performed on nucleic acid arrays
02/04/1999CA2297175A1 Polyethylenimine-based biomolecule arrays
02/03/1999EP0895083A2 Reaction site array, preparation of it, reaction process using it and quantitative determination method of substance in sample solution using it
02/03/1999EP0895082A2 Method of spotting probe on solid support, probe array and method of manufacturing thereof, and method of detecting target substance and method of identifying structure of target substance using probe array
02/03/1999EP0786085A4 Method and apparatus for efficient mimotope discovery
02/02/1999US5866345 Typically single-use, modules capable of receiving and rapidly conducting a predetermined assay protocol on a fluid sample.
02/02/1999US5866344 Antibody selection methods using cell surface expressed libraries
02/02/1999US5866330 Isolating and analyzing short defined sequence tags corresponding to expressed genes
02/01/1999CA2244414A1 Reaction site array, preparation process of it, reaction process using it and quantitative determination method of substance in sample solution using it
02/01/1999CA2244403A1 Method of spotting probe on solid support, probe array and method of manufacturing thereof, and method of detecting target substance and method of identifying structure of target substance using probe array
01/1999
01/28/1999WO1999003341A1 Parallel production of high density arrays
01/27/1999EP0558671B1 Synthesis of equimolar multiple oligomer mixtures, especially of oligopeptide mixtures
01/27/1999EP0542770B1 Random bio-oligomer library, a method of synthesis thereof, and a method of use thereof
01/26/1999US5863708 Forming first and second passages each extending through dielectric substrate, forming plurality of channels on said first and second surfaces of dielectric substrate, forming a plurality of reservoirs; for conducting reactions in parallel
01/26/1999US5863502 Economical, automated, high temperature microreactor with valves suitable for use in conducting multiple, parallel pcr assays, pathogen assays, combinatorial chemistry; medical diagnosis; noncontamination; seals to prevent vapor loss
01/21/1999WO1999002733A1 Identification of molecular targets
01/21/1999WO1999002266A1 A device for performing an assay, a method for manufacturing said device, and use of a membrane in the manufacture of said device
01/21/1999CA2792122A1 In vitro sorting method
01/21/1999CA2584453A1 A method for increasing the concentration of nucleic acids
01/20/1999EP0891811A1 Method and apparatus for mixing a thin film of fluid
01/19/1999US5861351 Mixing a solvent, a carboxylic acid, a radical scavenger, and an organopalladium compound
01/19/1999US5861247 Rapid method to detect duplex formation in sequencing by hybridization methods
01/19/1999US5861242 Array of oligonucleotide probes immobilized on a solid support for analysis of a target sequence from a human immunodeficiency virus
01/19/1999US5861125 Continuous flow reactor which includes a sample bearing membrane strip optionally coated with polybrene
01/13/1999EP0890651A1 Analysing chip with local heating electrodes
01/12/1999US5858804 Immunological assay conducted in a microlaboratory array
01/12/1999US5858731 Nucleotide sequences including nondegenerate and degenerate nucleotide bases which can be ligated together for longer molecules; for rapid and efficient synthesis of preselected sequences for dna sequencing, polymerase chain reaction
01/12/1999US5858670 Screening randomly synthesized oligopeptide- or oligonucleotide-solid phase libraries with acceptor molecules (e.g. antibodies), isolating solid phase support/oligomer bound to molecule, sequencing oligomer
01/12/1999US5858659 Polymorphism detection
01/12/1999US5858193 Electrokinetic pumping
01/07/1999WO1999000663A1 Compositionally different polymer-based sensor elements and methods for preparing same
01/07/1999WO1999000657A1 High density sample holder for analysis of biological samples
01/05/1999US5856101 Dna sequences
12/1998
12/30/1998WO1998059362A1 Retentate chromatography and protein chip arrays with applications in biology and medicine
12/30/1998WO1998059361A1 Retentate chromatography and protein chip arrays with applications in biology and medicine
12/30/1998WO1998059360A1 Retentate chromatography and protein chip arrays with applications in biology and medicine
12/30/1998WO1998058967A1 Self-assembling peptide surfaces for cell patterning and interactions
12/30/1998WO1998058745A1 Electrospraying solutions of substances for mass fabrication of chips and libraries
12/30/1998CA2294449A1 Electrospraying solutions of substances for mass fabrication of chips and libraries
12/30/1998CA2294417A1 Retentate chromatography and protein chip arrays with applications in biology and medicine
12/30/1998CA2294416A1 Retentate chromatography and protein chip arrays with applications in biology and medicine
12/29/1998US5854026 Human growth hormone variant having enhanced affinity for human growth hormone receptor at site 1
12/29/1998US5853668 Apparatus allowing sequential chemical reactions
12/29/1998CA1340288C Generation and selection of novel binding proteins
12/23/1998WO1998058085A1 High throughput screening for novel enzymes
12/23/1998WO1998058080A1 A method for in vitro molecular evolution of protein function
12/23/1998WO1998057980A1 Peptides and compounds that bind to the il-5 receptor
12/23/1998EP0886143A1 Apparatus for screening compound libraries
12/23/1998EP0869850A4 Method of producing micro-electrical conduits
12/23/1998EP0637999B1 Polynucleotide amplification analysis using a microfabricated device
12/23/1998CN1202929A Apparatus and methods for active programmable matrix devices
12/23/1998CA2294519A1 Peptides and compounds that bind to the il-5 receptor
12/23/1998CA2294380A1 High throughput screening for novel enzymes
12/22/1998US5852167 Totally synthetic affinity reagents
12/22/1998US5851772 Microchip method for the enrichment of specific DNA sequences
12/17/1998WO1998056915A2 Artificial antibody polypeptides
12/17/1998WO1998056770A1 Method for producing quinazoline-diones in solid phase and use of the same
12/17/1998DE19724983A1 Verfahren zur Herstellung von Chinazolindionen an fester Phase und ihre Verwendung Process for the preparation of quinazolinediones on a solid phase, and their use
12/17/1998CA2294175A1 Method for producing quinazoline-diones in solid phase and use of the same
12/16/1998EP0884394A2 Apparatus for assembly of an in situ PCR sample and reagent fluid containment system on a glass slide
12/16/1998EP0883806A1 Catalyst testing process and apparatus
12/16/1998EP0883686A1 Novel method for the identification of nucleic acid sequences encoding two or more interacting (poly)peptides
12/16/1998EP0883442A1 Electrokinetic pumping
12/15/1998US5849500 Phagemid for antibody screening
12/15/1998US5849486 Methods for hybridization analysis utilizing electrically controlled hybridization
12/10/1998WO1998055449A1 Hydroxamic acid compounds having anticancer and anti-parasitic properties
12/10/1998WO1998047343A3 Antibodies or binding protein libraries displayed on phage, cells, or other replicatable genetic packages
12/08/1998US5847105 Methods for performing multiple sequential reactions on a matrix
12/08/1998US5847019 Photoactivatable polymers for producing patterned biomolecular assemblies
12/08/1998US5846841 Motif Libraries
12/08/1998US5846765 Identification of novel substrates
12/08/1998US5846724 Highly specific surface for biological reactions having an exposed ethylenic double bond, process of using the surface, and method for assaying for a molecule using the surface
12/08/1998US5846719 Oligonucleotide tags for sorting and identification
12/08/1998US5846708 Optical and electrical methods and apparatus for molecule detection
12/08/1998US5846396 Liquid distribution system
12/03/1998WO1998041534A3 Multifunctional ceramic particles as supports for solid phase and combinatorial synthesis
12/02/1998EP0880558A1 Combinatorial process for preparing substituted indane libraries
12/02/1998EP0527839B1 Recombinant library screening methods
12/01/1998US5844076 Totally synthetic affinity reagents
12/01/1998US5843767 Microfabricated, flowthrough porous apparatus for discrete detection of binding reactions
12/01/1998US5843656 Recombinant clone selection system
12/01/1998US5843655 Methods for testing oligonucleotide arrays
11/1998
11/26/1998WO1998053103A1 Nucleic acid arrays
11/26/1998WO1998053093A1 Color-encoding and in-situ interrogation of matrix-coupled chemical compounds
11/26/1998WO1998053060A1 Nucleic acid binding proteins
11/26/1998WO1998053058A1 Nucleic acid binding proteins