Patents for C40B 40 - Libraries per se, e.g. arrays, mixtures (17,361)
11/2000
11/09/2000WO2000031236A3 Vectors for gene mutagenesis and gene discovery by gene trapping
11/08/2000EP1050588A1 A device for performing an assay, use of a membrane in the manufacture of said device, kit comprising said device and method for the detection of an analyte using such device
11/07/2000US6143523 Nucleotide sequences coding somatotropin; for treatment of defect associated with reduction in somatotropin
11/07/2000US6143499 Miniaturized reaction vessel system, method for performing site-specific biochemical reactions and affinity fractionation for use in DNA sequencing
11/07/2000US6143497 Synthesizing random oligomers on particles using identification tags to facilitate identification of sequence of monomers
11/07/2000US6143252 Apparatus for multiple and parallel synthesis of different oligonucleotides
11/02/2000WO2000065326A1 Automated method for examining catalytic and spectroscopic properties of the components of combinatorial libraries
11/02/2000EP1048723A1 Biochip and method of using biochip
11/02/2000EP1047942A1 Methods and compositions for the identification of growth factor mimetics, growth factors and inhibitors
11/02/2000DE19918956A1 Verfahren zur automatisierten Untersuchung katalytischer und spektroskopischer Eigenschaften der Komponenten kombinatorischer Bibliotheken Method for the automated analysis of catalytic and spectroscopic properties of the components of combinatorial libraries
11/01/2000CN1272218A Retentate chromatography and protein chip arrays with applications in biology and medicine
10/2000
10/31/2000US6140493 Method of synthesizing diverse collections of oligomers
10/31/2000US6140135 Multifunctional surfaces
10/31/2000US6140110 Apparatus for multi-zone polymerase chain reaction
10/31/2000US6140044 Methods and devices for packaging a substrate having an array of probes fabricated on its surface are disclosed
10/31/2000US6139831 Apparatus and method for immobilizing molecules onto a substrate
10/26/2000WO2000063701A2 Microarrays of polypeptides
10/26/2000WO2000063695A1 Encoding of microcarriers
10/26/2000WO2000063437A2 Detection of nucleic acid reactions on bead arrays
10/26/2000WO2000063419A1 Combinatorial chemical library supports having indicia at coding positions and methods of use
10/26/2000WO2000020428A9 Synthesis of oligosaccharides, reagents and methods related thereto
10/26/2000WO2000020112A3 Chemical constructs and their uses
10/26/2000WO2000018905A9 Method of producing permuteins by scanning permutagenesis
10/26/2000WO2000013018B1 Support for a method for determining analytes and a method for producing the support
10/26/2000DE19960346A1 Applying materials to a support, useful for combinatorial synthesis of peptides, e.g. for diagnosis, by incorporating materials in meltable particles and delivery through a printer
10/26/2000CA2366123A1 Microarrays of polypeptides
10/26/2000CA2366093A1 Combinatorial chemical library supports having indicia at coding positions and methods of use
10/25/2000EP1046421A2 Methods and reagents for very large scale immobilized polymer synthesis
10/25/2000EP1046036A1 Methods for obtaining probes of peptide function
10/25/2000EP1045819A1 Method for producing mass-coded combinatorial libraries
10/24/2000US6138077 Method, apparatus and computer program product for determining a set of non-hybridizing oligonucleotides
10/24/2000US6136569 Accurate method for identifying genes encoding secreted and membrane-bound proteins using a starch degrading enzyme as a reporter molecule
10/24/2000US6136555 Purification method and apparatus
10/24/2000US6136269 Combinatorial kit for polymer synthesis
10/19/2000WO2000061818A1 Multiplex amplification and separation of nucleic acid sequences using ligation-dependent strand displacement amplification and bioelectronic chip technology
10/19/2000WO2000061720A2 Allele-specific strand displacement amplification primers and method
10/19/2000WO2000061594A2 Nucleoside derivatives with photo-unstable protective groups
10/19/2000WO2000061282A1 Porous silica substrates for polymers synthesis and assays
10/19/2000WO2000061281A1 Encoding scheme for solid phase chemical libraries
10/19/2000WO2000036398A3 Method and devices for detecting optical properties, especially luminescence reactions and refraction behaviour of molecules which are directly or indirectly bound on a support
10/19/2000DE19915867A1 New nucleoside derivatives with photolabile protecting groups, useful in oligonucleotide synthesis, particularly on solid phases, e.g. for hybridization testing
10/19/2000CA2367541A1 Encoding scheme for solid phase chemical libraries
10/18/2000EP1045031A2 Amplification and detection of Yersinia enterocolitica
10/18/2000EP1044375A1 Method comprising capture molecule fixed on disc surface
10/17/2000US6133436 Increased surface area for immobilization of nucleic acids; for use in hybridizations
10/17/2000US6133409 Reacting a solid support-bound n-alkylated hydroxamic acid with a carbon-nitrogen cleaving organometallic compund to liberate the product ketone
10/17/2000US6133046 Microsystems for biological analyses, their use for detecting analytes, and method for producing them
10/17/2000US6132970 Rearranging nucleotide sequences; extending chains of nucleotide sequence with regions of both homogeneity and heterogeneity in multiple cycles, screening rearranged nucleotide sequences to detect desired properties
10/17/2000CA2163781C Method and apparatus for conducting an array of chemical reactions on a support surface
10/12/2000WO2000060356A1 Miniaturized cell array methods and apparatus for cell-based screening
10/12/2000WO2000060345A1 Method for screening crystallization conditions in solution crystal growth
10/12/2000WO2000060126A2 Quantitative assay for expression of genes in microarray
10/12/2000WO2000060125A2 High resolution dna detection methods and devices
10/12/2000WO2000060116A1 High throughput and high sensitivity detection assays
10/12/2000WO2000060070A1 A polypeptide structure for use as a scaffold
10/12/2000WO2000059627A1 Formulation arrays and use thereof
10/12/2000WO2000035940A3 Method and devices for applying substances to a support, especially monomers for the combinatorial synthesis of molecule libraries
10/12/2000WO2000023182A3 Method of bonding bio-molecules to a test site
10/12/2000WO2000017643A3 A system for cell-based screening
10/12/2000CA2369935A1 Method for screening crystallization conditions in solution crystal growth
10/12/2000CA2368773A1 Miniaturized cell array methods and apparatus for cell-based screening
10/12/2000CA2367405A1 High resolution dna detection methods and devices
10/12/2000CA2367212A1 A polypeptide structure for use as a scaffold
10/12/2000CA2365851A1 Formulation arrays and use thereof
10/12/2000CA2303303A1 Amplification and detection of yersinia enterocolitica
10/11/2000EP1042357A1 Process for the preparation of solid polymer composites
10/11/2000EP1042337A2 Oligonucleotide synthesis using high boiling point solvents
10/11/2000EP1042279A1 Substituted beta-alanines
10/11/2000EP1042060A1 Method and apparatus for chemical synthesis
10/11/2000EP1041877A1 Parallel production of high density arrays
10/11/2000CN1269883A Method of making high density arrays
10/10/2000US6130046 Designing nucleic acid probes which will bind to control sequence and have been formed with at least one common and at least one different nucleotide addtion cycle
10/10/2000US6130044 Surfaces for biological reactions, process for preparing them and process for their use
10/10/2000US6130037 Biosensor device and method
10/10/2000US6129896 Biosensor chip and manufacturing method
10/08/2000CA2268695A1 Apparatus and method for analyzing information in arrays of information sites
10/05/2000WO2000058504A1 High throughput screening method for determining enantioselectivity
10/05/2000WO2000058211A2 Catalyst system for producing carbon fibrils
10/05/2000WO2000058003A1 Method for preparing and screening catalysts
10/05/2000WO2000013004A9 Combinatorial polymer synthesis of sensors for polymer-based sensor arrays
10/05/2000DE10011400A1 Targeted photolytic deprotection of nucleoside derivatives, useful for synthesis of DNA chips, includes coating with a gel or viscous liquid before illumination
10/05/2000CA2368749A1 High-throughput-screening method for determining enantioselectivity
10/04/2000EP1041514A2 Method and apparatus for selectively displaying measurement result and corresponding images
10/04/2000EP1041385A2 Method and apparatus for detecting an organism-originated substance
10/04/2000EP1040352A1 Solid-phase tips and uses relating thereto
10/04/2000EP1040348A1 Method for combinatorial material development using differential thermal images
10/04/2000CN1268979A Multiple functionilities within an array element and uses thereof
10/04/2000CN1268905A Laminated assembly for active bioelectronic device
10/03/2000US6127190 Method for producing combinatorial libraries having a predetermined frequency of each species of test compound
10/03/2000US6127132 Aggregation of expression vectors which code fusion protein for the isolation of high receptivity antibodies
10/03/2000US6127125 Sample application method and device
10/03/2000US6126904 Apparatus and methods for the preparation of chemical compounds
09/2000
09/28/2000WO2000056934A1 Continuous porous matrix arrays
09/28/2000WO2000056927A2 Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays
09/28/2000WO2000056724A1 Oxazole and thiazole combinatorial libraries
09/28/2000WO2000056681A1 Thiourea and urea liquid-phase combinatorial libraries: synthesis and apoptosis induction
09/28/2000WO2000056455A2 Pressure-pulse actuated liquid dispensing apparatus
09/28/2000WO2000056445A1 Polymer synthesizer
09/28/2000WO2000056444A2 Spatially directed interaction on a solid surface
09/28/2000DE19913858A1 High-Throughput-Screening-Verfahren zur Bestimmung der Enantioselektivität asymmetrisch verlaufender Reaktionen High-throughput screening method for determining the enantioselectivity of asymmetric extending reactions