Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210) |
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04/11/1985 | WO1985001516A1 Vectors for the expression of an antigenic protein of rabies in eucaryotic cells and application thereof to the preparation of a vaccine |
04/11/1985 | WO1985001515A1 T-cell growth factor of the gibbon ape |
04/11/1985 | WO1985001503A1 Superoxide dismutase cloning and expression in microorganisms |
04/10/1985 | EP0136907A2 A xenogeneic expression control system, a method of using it, expression vectors containing it, cells transformed thereby and heterologous proteins produced therefrom |
04/10/1985 | EP0136835A2 Process for the preparation of antibody compositions of therapeutic agents having an extended serum half-life |
04/10/1985 | EP0136829A2 Improved expression vector and use thereof |
04/10/1985 | EP0136694A2 Production of monomeric human gamma-interferon |
04/10/1985 | EP0136620A1 Homogeneous immune interferon fragment |
04/10/1985 | EP0136573A1 Novel double-stranded DNA |
04/10/1985 | EP0136521A2 Novel, double-stranded DNA |
04/10/1985 | EP0136490A2 DNA plasmids |
04/10/1985 | EP0136489A1 Analogs of human interleukin II and their preparation |
04/10/1985 | EP0136472A1 Production of secretin |
04/10/1985 | EP0136359A1 Process for preparing l-histidine |
04/10/1985 | EP0136353A1 Serum-free animal cell culture medium and method for the primary culture and obtention of cell lines using such medium. |
04/09/1985 | US4510245 Yeast expression vector; genetic engineering |
04/09/1985 | CA1185197A1 Lysozyme-sensitive microorganism |
04/03/1985 | EP0136090A2 Improvements in or relating to expression plasmids |
04/03/1985 | EP0136035A2 Associations of prokaryotic organisms and eukaryotic plant cells |
04/03/1985 | EP0135953A2 Process for cell disruption |
04/03/1985 | EP0135712A2 Antigens and monoclonal antibodies reactive against sporozoites of eimeria spp. |
04/02/1985 | US4508827 Plasmid containing dna vectors |
04/02/1985 | US4508826 Bacteriophage DNA cloning vector TG1 and microorganisms containing TG1 |
04/02/1985 | US4508824 Transconjugal mating to transmit plasmid |
04/02/1985 | US4508823 Genetic engineering-chromosomal dna splitting with enzyme, then joining to hgive plasmid/- |
04/02/1985 | US4508738 Non-sucrose fermenting Pedioccus pentosaceus |
03/28/1985 | WO1985001297A1 Inviable phages, their production and dna thereof |
03/28/1985 | WO1985001296A1 Yeast hybrid vectors |
03/27/1985 | EP0135347A1 Human renin and cDNA encoding therefor |
03/27/1985 | EP0135291A1 A modified antibiotic resistance gene |
03/27/1985 | EP0135278A2 Plasmid vector for mammalian cells |
03/27/1985 | EP0135159A2 Monoclonal antibody having specificity for the double-stranded conformation of native DNA and diagnostic methods using same |
03/27/1985 | EP0135094A1 Microbial expression of insulin-like growth factor |
03/27/1985 | EP0135073A2 Antigens and monoclonal antibodies reactive against merozites of eimeria spp. |
03/27/1985 | EP0135045A2 A novel plasmid and methods for its use |
03/27/1985 | EP0134803A1 Monoclonal antibody |
03/20/1985 | EP0134773A1 Yeast copper-metallothionein gene |
03/20/1985 | EP0134673A1 Improved plasmid vector and use thereof |
03/20/1985 | EP0134662A1 Production of bovine calf chymosin |
03/20/1985 | EP0134631A1 Peptides, pharmaceutical compositions, genes, vectors, host organisms, processes for their production and diagnostic reagents |
03/20/1985 | EP0134552A2 Monoclonal antibody with a high affinity for digoxin |
03/20/1985 | EP0134536A2 Process for obtaining and multiplying defective, non infectious virus genomes |
03/19/1985 | US4506044 Microbial heteropolysaccharide |
03/19/1985 | US4506017 Modified Pasteurella haemolytica bacteria |
03/19/1985 | US4506014 Plasmid pAC 1, a process for obtaining it and its use |
03/19/1985 | US4506013 Stabilizing and selecting recombinant DNA host cells |
03/14/1985 | WO1985001067A1 Recombinant materials and methods for producing human connective tissue-activating peptide-iii and analogs thereof |
03/14/1985 | WO1985001066A1 Process for producing peptide |
03/14/1985 | WO1985001051A1 Oligonucleotide polymeric support system |
03/14/1985 | WO1985000974A1 Antibody compositions of therapeutic agents having an extended serum half-life |
03/13/1985 | EP0134085A1 DNA encoding a GRF precursor |
03/13/1985 | EP0134048A1 Molecular cloning and expression in industrial microorganism species |
03/13/1985 | EP0133978A2 Process for cell fusion |
03/12/1985 | US4504581 Method for producing L-histidine by fermentation |
03/06/1985 | EP0133756A2 Vector for expression of polypeptides |
03/05/1985 | US4503155 Antibiotic resistance |
03/05/1985 | US4503151 Recombinant cDNA construction method and hybrid nucleotides useful in cloning |
03/05/1985 | US4503142 Genetic engineering, cloning, immunoassay |
03/05/1985 | CA1183470A1 Hybrid cell line for producing monoclonal antibody to a human prothymocyte antigen, antibody, and methods |
03/05/1985 | CA1183469A1 Hybrid cell line for producing complement-fixing monoclonal antibody to human suppressor t cells, antibody, and method |
03/05/1985 | CA1183468A2 Hybrid cell line for producing monoclonal antibody to a human t cell antigen, antibody, and methods |
03/05/1985 | CA1183361A1 Compositions containing and methods of use of an infectivity-cured hr plasmid-bearing microorganism |
02/28/1985 | WO1985000832A1 Production of streptococal m protein immunogens and molecular probes |
02/28/1985 | WO1985000831A1 Microbial expression of insulin-like growth factor |
02/28/1985 | WO1985000829A1 Dna plasmids |
02/28/1985 | WO1985000828A1 Associations of prokaryotic organisms and eukaryotic plant cells |
02/28/1985 | WO1985000817A1 Microbial expression of interleukin ii |
02/28/1985 | WO1985000813A1 Nucleic acid branched junctions with precisely defined migrational mobility |
02/28/1985 | WO1985000807A1 Polypeptide-induced monoclonal antibodies to oncoproteins |
02/28/1985 | WO1985000750A1 Hybridoma cell line producing suppressive factor of allergy |
02/27/1985 | EP0133599A2 Vaccines and compositions against hepatitis B viral infections |
02/27/1985 | EP0133551A2 Monoclonal antibody which recognizes a structure which is common to the human interleukin-2 (TCGF) and to the light chain lambda of human immunoglobulin, and hybridoma cell lines producing this monoclonal antibody |
02/27/1985 | EP0133540A1 Receptor assays using labeled monoclonal anti-idiotypic antibodies |
02/27/1985 | EP0133473A2 In vivo labelling of polynucleotide sequences |
02/26/1985 | CA1183090A1 Genetically engineered microorganisms for massive production of amylolytic enzymes and process for preparing same |
02/20/1985 | EP0133403A2 Nucleotide sequence coding for the signal peptide of diphteria toxin, vector containing this nucleotide sequence, its use in the transformation of microorganisms and peptide compositions obtained therefrom. |
02/20/1985 | EP0133321A1 DNA gene, process for production thereof and plasmid containing the same |
02/20/1985 | EP0133288A2 Bacterial detection by nucleic acid hybridization, labeled probes and test kit therefore |
02/20/1985 | EP0133282A1 Preparation of acidamide-carboxy-terminal polypeptides |
02/19/1985 | US4500640 Resistant to streptomycin and/or spectinomycin- cloning vector |
02/14/1985 | WO1985000621A1 Process for the definite cross-linking of double helix dna fragments by means of a linkage dna as well as oligonucleotides used as linkage dna |
02/13/1985 | EP0133123A1 Immunogens of papilloma viruses |
02/13/1985 | EP0133046A2 A method of introducing a donor DNA into a strain of the genus Lactobacillus |
02/13/1985 | EP0133044A1 Stabilising foreign proteins, and plasmids for use therein |
02/13/1985 | EP0132621A2 Autoradiographic gene-screening method |
02/12/1985 | US4499189 Bacteria carrying plasmid having temperature dependent plasmid copy number |
02/12/1985 | US4499188 Bacterial production of heterologous polypeptides under the control of a repressible promoter-operator |
02/12/1985 | CA1182409A1 Plasmids constructed by gene manipulation, strains of escherichia coli carrying them, and process of tryptophan production using said strains |
02/12/1985 | CA1182408A1 Method and vector organism for transported cloned heterologous gene products in bacillus subtilis |
02/12/1985 | CA1182407A1 MICROBIOLOGICAL SYNTHESIS OF .beta. ENDORPHIN |
02/12/1985 | CA1182406A1 Hybrid cell line for producing complement-fixing monoclonal antibody to human t cells, antibody, and methods |
02/05/1985 | US4497796 Gene transfer in intact mammals |
01/31/1985 | WO1985000382A1 Molecular cloning and expression in industrial microorganism species |
01/31/1985 | WO1985000381A1 Proteins, pharmaceutical compositions, genes, vectors, host organisms and processes for their production |
01/31/1985 | WO1985000369A1 Hybrid dna synthesis of epidermal growth factor |
01/31/1985 | WO1985000314A1 Method and device for performing microoperations on cells |
01/30/1985 | EP0132309A2 Novel regulatable eukaryotic promoter element |
01/30/1985 | EP0132308A1 Biosynthetic 2,5-diketogluconic acid reductase, processes, recombinant cells and expression vectors for its production, and its use in preparing 2-keto-L-gulonic acid |
01/29/1985 | CA1181702A1 Hybrid cell line for producing monoclonal antibody to a human thymocyte antigen, antibody, and methods |
01/23/1985 | EP0131878A2 Process for producing human monoclonal antibodies |