Patents
Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210)
04/1985
04/11/1985WO1985001516A1 Vectors for the expression of an antigenic protein of rabies in eucaryotic cells and application thereof to the preparation of a vaccine
04/11/1985WO1985001515A1 T-cell growth factor of the gibbon ape
04/11/1985WO1985001503A1 Superoxide dismutase cloning and expression in microorganisms
04/10/1985EP0136907A2 A xenogeneic expression control system, a method of using it, expression vectors containing it, cells transformed thereby and heterologous proteins produced therefrom
04/10/1985EP0136835A2 Process for the preparation of antibody compositions of therapeutic agents having an extended serum half-life
04/10/1985EP0136829A2 Improved expression vector and use thereof
04/10/1985EP0136694A2 Production of monomeric human gamma-interferon
04/10/1985EP0136620A1 Homogeneous immune interferon fragment
04/10/1985EP0136573A1 Novel double-stranded DNA
04/10/1985EP0136521A2 Novel, double-stranded DNA
04/10/1985EP0136490A2 DNA plasmids
04/10/1985EP0136489A1 Analogs of human interleukin II and their preparation
04/10/1985EP0136472A1 Production of secretin
04/10/1985EP0136359A1 Process for preparing l-histidine
04/10/1985EP0136353A1 Serum-free animal cell culture medium and method for the primary culture and obtention of cell lines using such medium.
04/09/1985US4510245 Yeast expression vector; genetic engineering
04/09/1985CA1185197A1 Lysozyme-sensitive microorganism
04/03/1985EP0136090A2 Improvements in or relating to expression plasmids
04/03/1985EP0136035A2 Associations of prokaryotic organisms and eukaryotic plant cells
04/03/1985EP0135953A2 Process for cell disruption
04/03/1985EP0135712A2 Antigens and monoclonal antibodies reactive against sporozoites of eimeria spp.
04/02/1985US4508827 Plasmid containing dna vectors
04/02/1985US4508826 Bacteriophage DNA cloning vector TG1 and microorganisms containing TG1
04/02/1985US4508824 Transconjugal mating to transmit plasmid
04/02/1985US4508823 Genetic engineering-chromosomal dna splitting with enzyme, then joining to hgive plasmid/-
04/02/1985US4508738 Non-sucrose fermenting Pedioccus pentosaceus
03/1985
03/28/1985WO1985001297A1 Inviable phages, their production and dna thereof
03/28/1985WO1985001296A1 Yeast hybrid vectors
03/27/1985EP0135347A1 Human renin and cDNA encoding therefor
03/27/1985EP0135291A1 A modified antibiotic resistance gene
03/27/1985EP0135278A2 Plasmid vector for mammalian cells
03/27/1985EP0135159A2 Monoclonal antibody having specificity for the double-stranded conformation of native DNA and diagnostic methods using same
03/27/1985EP0135094A1 Microbial expression of insulin-like growth factor
03/27/1985EP0135073A2 Antigens and monoclonal antibodies reactive against merozites of eimeria spp.
03/27/1985EP0135045A2 A novel plasmid and methods for its use
03/27/1985EP0134803A1 Monoclonal antibody
03/20/1985EP0134773A1 Yeast copper-metallothionein gene
03/20/1985EP0134673A1 Improved plasmid vector and use thereof
03/20/1985EP0134662A1 Production of bovine calf chymosin
03/20/1985EP0134631A1 Peptides, pharmaceutical compositions, genes, vectors, host organisms, processes for their production and diagnostic reagents
03/20/1985EP0134552A2 Monoclonal antibody with a high affinity for digoxin
03/20/1985EP0134536A2 Process for obtaining and multiplying defective, non infectious virus genomes
03/19/1985US4506044 Microbial heteropolysaccharide
03/19/1985US4506017 Modified Pasteurella haemolytica bacteria
03/19/1985US4506014 Plasmid pAC 1, a process for obtaining it and its use
03/19/1985US4506013 Stabilizing and selecting recombinant DNA host cells
03/14/1985WO1985001067A1 Recombinant materials and methods for producing human connective tissue-activating peptide-iii and analogs thereof
03/14/1985WO1985001066A1 Process for producing peptide
03/14/1985WO1985001051A1 Oligonucleotide polymeric support system
03/14/1985WO1985000974A1 Antibody compositions of therapeutic agents having an extended serum half-life
03/13/1985EP0134085A1 DNA encoding a GRF precursor
03/13/1985EP0134048A1 Molecular cloning and expression in industrial microorganism species
03/13/1985EP0133978A2 Process for cell fusion
03/12/1985US4504581 Method for producing L-histidine by fermentation
03/06/1985EP0133756A2 Vector for expression of polypeptides
03/05/1985US4503155 Antibiotic resistance
03/05/1985US4503151 Recombinant cDNA construction method and hybrid nucleotides useful in cloning
03/05/1985US4503142 Genetic engineering, cloning, immunoassay
03/05/1985CA1183470A1 Hybrid cell line for producing monoclonal antibody to a human prothymocyte antigen, antibody, and methods
03/05/1985CA1183469A1 Hybrid cell line for producing complement-fixing monoclonal antibody to human suppressor t cells, antibody, and method
03/05/1985CA1183468A2 Hybrid cell line for producing monoclonal antibody to a human t cell antigen, antibody, and methods
03/05/1985CA1183361A1 Compositions containing and methods of use of an infectivity-cured hr plasmid-bearing microorganism
02/1985
02/28/1985WO1985000832A1 Production of streptococal m protein immunogens and molecular probes
02/28/1985WO1985000831A1 Microbial expression of insulin-like growth factor
02/28/1985WO1985000829A1 Dna plasmids
02/28/1985WO1985000828A1 Associations of prokaryotic organisms and eukaryotic plant cells
02/28/1985WO1985000817A1 Microbial expression of interleukin ii
02/28/1985WO1985000813A1 Nucleic acid branched junctions with precisely defined migrational mobility
02/28/1985WO1985000807A1 Polypeptide-induced monoclonal antibodies to oncoproteins
02/28/1985WO1985000750A1 Hybridoma cell line producing suppressive factor of allergy
02/27/1985EP0133599A2 Vaccines and compositions against hepatitis B viral infections
02/27/1985EP0133551A2 Monoclonal antibody which recognizes a structure which is common to the human interleukin-2 (TCGF) and to the light chain lambda of human immunoglobulin, and hybridoma cell lines producing this monoclonal antibody
02/27/1985EP0133540A1 Receptor assays using labeled monoclonal anti-idiotypic antibodies
02/27/1985EP0133473A2 In vivo labelling of polynucleotide sequences
02/26/1985CA1183090A1 Genetically engineered microorganisms for massive production of amylolytic enzymes and process for preparing same
02/20/1985EP0133403A2 Nucleotide sequence coding for the signal peptide of diphteria toxin, vector containing this nucleotide sequence, its use in the transformation of microorganisms and peptide compositions obtained therefrom.
02/20/1985EP0133321A1 DNA gene, process for production thereof and plasmid containing the same
02/20/1985EP0133288A2 Bacterial detection by nucleic acid hybridization, labeled probes and test kit therefore
02/20/1985EP0133282A1 Preparation of acidamide-carboxy-terminal polypeptides
02/19/1985US4500640 Resistant to streptomycin and/or spectinomycin- cloning vector
02/14/1985WO1985000621A1 Process for the definite cross-linking of double helix dna fragments by means of a linkage dna as well as oligonucleotides used as linkage dna
02/13/1985EP0133123A1 Immunogens of papilloma viruses
02/13/1985EP0133046A2 A method of introducing a donor DNA into a strain of the genus Lactobacillus
02/13/1985EP0133044A1 Stabilising foreign proteins, and plasmids for use therein
02/13/1985EP0132621A2 Autoradiographic gene-screening method
02/12/1985US4499189 Bacteria carrying plasmid having temperature dependent plasmid copy number
02/12/1985US4499188 Bacterial production of heterologous polypeptides under the control of a repressible promoter-operator
02/12/1985CA1182409A1 Plasmids constructed by gene manipulation, strains of escherichia coli carrying them, and process of tryptophan production using said strains
02/12/1985CA1182408A1 Method and vector organism for transported cloned heterologous gene products in bacillus subtilis
02/12/1985CA1182407A1 MICROBIOLOGICAL SYNTHESIS OF .beta. ENDORPHIN
02/12/1985CA1182406A1 Hybrid cell line for producing complement-fixing monoclonal antibody to human t cells, antibody, and methods
02/05/1985US4497796 Gene transfer in intact mammals
01/1985
01/31/1985WO1985000382A1 Molecular cloning and expression in industrial microorganism species
01/31/1985WO1985000381A1 Proteins, pharmaceutical compositions, genes, vectors, host organisms and processes for their production
01/31/1985WO1985000369A1 Hybrid dna synthesis of epidermal growth factor
01/31/1985WO1985000314A1 Method and device for performing microoperations on cells
01/30/1985EP0132309A2 Novel regulatable eukaryotic promoter element
01/30/1985EP0132308A1 Biosynthetic 2,5-diketogluconic acid reductase, processes, recombinant cells and expression vectors for its production, and its use in preparing 2-keto-L-gulonic acid
01/29/1985CA1181702A1 Hybrid cell line for producing monoclonal antibody to a human thymocyte antigen, antibody, and methods
01/23/1985EP0131878A2 Process for producing human monoclonal antibodies