| Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210) |
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| 04/09/1986 | EP0177228A1 The use of bacteriophage lambda PL promoter to produce a functional polypeptide in streptomyces |
| 04/09/1986 | EP0176971A2 Gene coding for thermostable beta-galactosidase, Bacillus subtilis having the gene, enzyme coded by the gene and a process for the production thereof |
| 04/09/1986 | EP0176916A2 Process for production of gamma-interferon |
| 04/08/1986 | CA1202918A1 Eukaryotic autonomously replicating segment |
| 04/08/1986 | CA1202917A1 Process for producing subculturable lymphokine- producing human t cell hybridomas |
| 04/08/1986 | CA1202892A1 Tumor imaging with radiolabeled monoclonal antibodies |
| 04/02/1986 | EP0176493A1 Vaccinal polypeptides |
| 04/02/1986 | EP0176429A1 Compositions and process for protecting T lymphocytes against the etiological agent of lymphadenopathy and an acquired immunodepression syndrom |
| 04/02/1986 | EP0176396A1 Probes containing modified adenine groups, their preparation and uses |
| 04/02/1986 | EP0176365A2 Human monoclonal antibody and its preparation |
| 04/02/1986 | EP0176349A2 Methods of altering cells to increase production of a desired compound, cells capable of biosynthesis of a desired compound, methods of producing desired compounds and methods of selecting mutant cells exhibiting increased production of a desired compound |
| 04/02/1986 | EP0176341A1 An improved derivative of the tryptophan operon for expression of fused gene products |
| 04/02/1986 | EP0176340A1 Method of cloning modified streptomycetes DNA |
| 04/02/1986 | EP0176321A1 Recombinant dna cosmid shuttle vectors |
| 04/02/1986 | EP0176320A1 A method for expression and secretion in bacillus |
| 04/02/1986 | EP0176319A1 Method of selecting recombinant dna-containing streptomyces |
| 04/02/1986 | EP0176199A1 Plasmid pHJL210 and related bifunctional cloning vectors for use in streptomycetes |
| 04/02/1986 | EP0176170A1 Herpes simplex virus as a vector |
| 04/02/1986 | EP0176112A1 Process for introducing foreign DNA into genome of plants |
| 04/02/1986 | EP0175966A1 Plant cell microinjection technique |
| 04/02/1986 | EP0175852A2 Method for producing useful substances using genetically engineered viral DNA |
| 04/02/1986 | EP0175699A1 Bacterial strains |
| 04/02/1986 | EP0175689A1 Method of detecting nucleic acid sequences. |
| 04/01/1986 | US4579827 Monoclonal antibodies to human gastrointestinal cancers and hybridoma method of production of the monoclonal antibodies |
| 04/01/1986 | US4579821 Fusion of dna promother/regulator with genes |
| 04/01/1986 | US4579661 Process in the purification of biologically active substances |
| 04/01/1986 | CA1202581A1 Adaptor molecules for dna and their application to synthesis of gene-derived products |
| 04/01/1986 | CA1202566A1 Separation of plasma proteins from cell culture systems |
| 03/27/1986 | WO1986001843A1 Method of obtaining cellulase deficient strains of white-rot fungi |
| 03/27/1986 | WO1986001834A1 Retroviral polypeptides associated with human cellular transformation |
| 03/27/1986 | WO1986001829A1 A vaccine utilizing an avirulent strain of a microbial pathogen |
| 03/27/1986 | WO1986001828A1 Cyclic double-stranded dna, process for its preparation, microorganism containing said cyclic double-stranded dna, and process for preparing protein containing antigen determinant site of poliovirus capside protein vp1 using the same |
| 03/27/1986 | WO1986001827A1 Cloned dna sequences, hybridizable with genomic rna of lymphadenopathy-associated virus (lav) |
| 03/27/1986 | WO1986001825A1 Bacillus strains with reduced extracellular protease levels |
| 03/27/1986 | WO1986001808A1 Monoclonal antibodies and their use |
| 03/27/1986 | WO1986001807A1 Monoclonal antibodies and their use |
| 03/27/1986 | WO1986001806A1 Monoclonal antibodies and their use |
| 03/27/1986 | WO1986001805A1 Monoclonal antibodies and their use |
| 03/27/1986 | WO1986001804A1 Monoclonal antibodies and their use |
| 03/27/1986 | WO1986001802A1 Antigens of plasmodium falciparum |
| 03/26/1986 | EP0175283A1 Recombinant dna and use thereof |
| 03/26/1986 | EP0175261A2 Hybrid particle immunogens |
| 03/25/1986 | US4578355 Plasmid cloning vector pAS1 |
| 03/25/1986 | US4578352 Culturing clostridium bacteria |
| 03/25/1986 | US4578335 Interleukin 2 receptor |
| 03/25/1986 | US4578168 Biological engineering |
| 03/25/1986 | CA1202258A1 Expression vector carrying a gene coding for a phosphate-binding protein, a method for preparing the same and a method for producing a polypeptide using the same |
| 03/25/1986 | CA1202257A1 Method for expressing a gene |
| 03/25/1986 | CA1202256A2 Microbial expression of quasi-synthetic genes |
| 03/25/1986 | CA1202255A1 Multifunctional cloning vectors for use in streptomyces, bacillus, and e. coli |
| 03/19/1986 | EP0174874A2 Hybrid cell line producing monoclonal antibody cytolytic to trichomonas vaginalis |
| 03/19/1986 | EP0174835A1 Human tissue plasminogen activator and recombinant DNA compounds |
| 03/19/1986 | EP0174810A2 Multidrug resistance in mammalian cell lines and isolation of determinant glycoprotein DNA |
| 03/19/1986 | EP0174791A2 Tryptophan overproducer mutants of cereal crops |
| 03/19/1986 | EP0174785A1 A positive retroregulatory element, plasmid and cells comprising said element and their production, a method of enhancing gene expression using said element and a method of enhancing RNA half life using said element |
| 03/19/1986 | EP0174759A1 Multispecific immunogenic proteins |
| 03/19/1986 | EP0174669A2 Process for the production of a hybrid DNA containing the complementary hepatitis A virus genome, this hybrid DNA and plasmid vector containing it, virus-specific proteins expressed by this hybrid DNA, vaccines containing and produced from these proteins |
| 03/19/1986 | EP0174608A1 Beta-actin gene and regulatory elements, preparation and use |
| 03/19/1986 | EP0174585A2 Promoters and the use thereof in the expression of unfused procaryotic or eucaryotic proteins in yeast |
| 03/19/1986 | EP0174444A2 Hepatitis surface antigen particle vaccine |
| 03/13/1986 | WO1986001539A1 Method of producing monoclonal anti-idiotypic antibodies |
| 03/13/1986 | WO1986001537A1 Application of antibiotics of the phleomycine family as selection agent in the field of genetic engineering |
| 03/13/1986 | WO1986001536A1 Bacillus thuringiensis crystal protein gene toxin segment |
| 03/13/1986 | WO1986001535A1 Molecular clones of the genome of htlv-iii |
| 03/13/1986 | WO1986001533A1 Production of chimeric antibodies |
| 03/13/1986 | WO1986001532A1 Polypeptide and polypeptide composition |
| 03/13/1986 | WO1986001517A1 Herpes virus specific immunological materials and methods |
| 03/13/1986 | WO1986001515A1 Expression of human connective tissue activator and related peptides |
| 03/13/1986 | WO1986001407A1 Monoclonal antibodies against metal chelates |
| 03/12/1986 | EP0174228A1 Process for diagnosing human Papilloma virus infections, monoclonal antibodies specific for a type of human Papilloma virus, and hybridomalines secreting them |
| 03/12/1986 | EP0174226A1 Probe and method for the detection of microorganisms, notably Legionella, in liquid media |
| 03/12/1986 | EP0174204A2 Gram-negative bacterial endotoxin blocking monoclonal antibodies and cells producing the same and formulations containing the same, and the production of all thereof |
| 03/12/1986 | EP0174166A1 Disarmed T-DNA |
| 03/12/1986 | EP0174143A1 Novel, distinct family of human leukocyte interferons, compositions containing them, methods for their production, and DNA and transfected hosts therefor |
| 03/12/1986 | EP0174096A2 Vectors for introducing DNA into bacterial chromosomes or for deleting it therefrom and for the production of protein |
| 03/12/1986 | EP0173997A1 Feline leukemia virus protein vaccines and their preparation |
| 03/12/1986 | EP0173973A2 Method for the determination of thyroid-stimulating hormone |
| 03/12/1986 | EP0173937A2 Method of increasing the permeability of yeast cells |
| 03/12/1986 | EP0173935A1 Hybrid lymphoblastoid-leukocyte human interferons |
| 03/12/1986 | EP0173924A2 Mechanical process for dislodging bacterial cells for the isolation of peptides prepared by recombinant techniques |
| 03/12/1986 | EP0173887A1 Novel interferon alphas |
| 03/11/1986 | CA1201669A1 Partition proficiency in genetically engineered plasmids for transforming gram-positive organisms |
| 03/11/1986 | CA1201668A1 Synthetic dna and method therefor |
| 03/11/1986 | CA1201667A1 Diagnostic reagent and method |
| 03/05/1986 | EP0173668A1 Recombinant saccharomyces |
| 03/05/1986 | EP0173663A2 The use of a specific tumor associated antigen, sialosyllactotetraose, in diagnostic or therapeutic procedures related to cancer deseases |
| 03/05/1986 | EP0173619A1 Method for the preparation of a strain, particularly from yeast, transformed by an expression vector, that can be propagated in a complete medium, without selection pressure, and strain thus obtained |
| 03/05/1986 | EP0173552A1 Recombinant DNA compounds and the expression of polypeptides such as tPA |
| 03/05/1986 | EP0173529A1 Molecular clones of the genome of HTLV-III |
| 03/05/1986 | EP0173494A2 Chimeric receptors by DNA splicing and expression |
| 03/05/1986 | EP0173378A2 Process for preparing a polypeptide by culturing a transformed microorganism, a transformed microorganism suitable therefor and DNA sequences suitable for preparing such microorganism |
| 03/05/1986 | EP0173341A1 Method for the determination of hormones |
| 03/05/1986 | EP0173327A2 Bialaphos producing gene |
| 03/05/1986 | EP0173280A1 Plasmids containing lambda Pl promoter, and engineered restriction site for convenient replacement of ribosomal binding site, hosts containing the plasmids and related methods |
| 03/05/1986 | EP0173254A1 DNA sequences of the EBV genome, recombinant DNA molecules, processes for producing EBV-related antigens, diagnostic compositions and pharmaceutical compositions containing said antigens |
| 03/05/1986 | EP0173215A2 Method for recovering purified growth hormones from genetically engineered microorganisms |
| 03/05/1986 | EP0173177A1 Enhancer for eukaryotic expression systems |
| 03/05/1986 | EP0173149A1 Synthetic regulation region |
| 03/04/1986 | CA1201396A1 Process for the preparation of permanent animal and human cell lines and their use |
| 02/27/1986 | WO1986001229A1 Method of removing n-terminal amino acid residues from eucaryotic polypetide analogs and polypeptides produced thereby |