| Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210) |
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| 07/02/1986 | EP0186643A1 Method for the production of vector plasmids capable of transforming an Escherichia coli host bacterium and to promote and control the expression of heterologous DNA |
| 07/02/1986 | EP0186631A1 PSM112 plasmid vector for expression in bacillus subtilis |
| 07/02/1986 | EP0186522A1 Cancer-specific DNA |
| 07/02/1986 | EP0186425A2 A selectable marker for development of vectors and transformation systems in plants |
| 07/02/1986 | EP0186379A1 Gene for insecticidal protein |
| 07/02/1986 | EP0186371A2 Monoclonal antibodies specific to antigens of Hepatitis B virus |
| 07/02/1986 | EP0186271A1 Method of characterising a test sample of genomic DNA |
| 07/02/1986 | EP0186098A1 Equine interferons |
| 07/02/1986 | EP0186069A2 New expression control sequence |
| 07/02/1986 | EP0186066A1 Glycoamylase gene |
| 07/02/1986 | EP0185870A2 Immunoassays for denatured protein analytes, particularly HB Alc, and monoclonal antibodies thereto |
| 07/02/1986 | EP0185700A1 Purifying recombinant dna products and checking product purity and efficiency of purification |
| 07/02/1986 | CA1206898A Monoclonal antibodies specific to an antigen on the surface of mature human t cells |
| 07/01/1986 | US4598049 General purpose gene synthesizer |
| 07/01/1986 | US4598048 Preparation of a maltogenic amylase enzyme |
| 07/01/1986 | US4598046 Biosynthesis |
| 06/25/1986 | EP0185573A1 Expression and excretion of polypeptides in eucaryotes under the control of an adenovirus promoter |
| 06/25/1986 | EP0185547A2 Polynucleotide hybridization assays employing catalyzed luminescence |
| 06/25/1986 | EP0185512A1 Method for stabilizing extra-chromosomal elements in bacteria during cultivation, extra-chromosomal elements, transformed bacteria and a method of producing a desired product in transformed bacteria |
| 06/25/1986 | EP0185444A2 Cloning and expression of HTLV-III DNA |
| 06/25/1986 | EP0185327A2 Process for producing alcohol |
| 06/25/1986 | EP0185135A2 Novel monoclonal antibody |
| 06/25/1986 | EP0185092A1 Process for preparing 5'-guanylic acid |
| 06/24/1986 | CA1206433A1 Production of biological products using resting cells |
| 06/19/1986 | WO1986003520A1 Method for the production of erythropoietin |
| 06/19/1986 | WO1986003519A1 Recombinant methods for production of serine protease inhibitors and dna sequences useful for same |
| 06/19/1986 | WO1986003517A1 Dna sequence encoding a hirudin-like protein and process for preparing such protein |
| 06/19/1986 | WO1986003516A1 Plant tranformation vector |
| 06/19/1986 | WO1986003410A1 A cloning vehicle for cloning a large fragment of dna and a vaccine comprising 987p fimbrial protein |
| 06/19/1986 | WO1986003408A1 Recombinant alveolar surfactant protein |
| 06/18/1986 | EP0185005A2 Insertion of the bacillus thuringiensis crystal protein gene into plant-colonizing microorganisms and their use |
| 06/17/1986 | US4595660 Molecular cloning with bifunctional plasmid vectors in Bacillus subtilis, mutants and substantially stably transformed mutants of Bacillus subtilis, and methods for utilizing the transformed mutants |
| 06/17/1986 | US4595658 Method for facilitating externalization of proteins synthesized in bacteria |
| 06/17/1986 | US4595654 With IgG mouse antibody produced by mouse lymphocyte myeloma hybridoma cell which specifically binds to human Clq but does not bind to human Cl |
| 06/17/1986 | CA1206109A1 E. coli having gene for production of staphylokinase and process for production of staphylokinase therewith |
| 06/17/1986 | CA1206108A1 Process for transforming microorganism by means of plasmid introduction |
| 06/11/1986 | EP0184576A1 Promoters for the expression of foreign genes in yeast, plasmids comprising them, and uses thereof for the production of polypeptides |
| 06/11/1986 | EP0184575A2 Transformed yeasts producing lysozyme, plasmids used for this transformation, and uses thereof |
| 06/11/1986 | EP0184438A2 Transforming aspergillus niger, and plasmids for use therein |
| 06/11/1986 | EP0184370A2 Monoclonal antibody specific for a mammary tumor cytoplasmic antigen |
| 06/11/1986 | EP0184369A2 Monoclonal antibody specific for a mammary tumor cell surface antigen |
| 06/11/1986 | EP0184355A2 Improvements in or relating to a process for purifying proteins |
| 06/11/1986 | EP0184187A2 Mouse-human chimaeric immunoglobulin heavy chain, and chimaeric DNA encoding it |
| 06/11/1986 | EP0184169A2 Method of producing heterologous proteins |
| 06/11/1986 | EP0184163A2 Preparation of a multicopy yeast vector |
| 06/11/1986 | EP0184086A2 Novel non-reverting salmonella live vaccines |
| 06/11/1986 | EP0184056A2 Large scale production of DNA probes |
| 06/11/1986 | EP0184017A2 Enhancement of nucleic acid hybridization by anionic polymers |
| 06/11/1986 | EP0183964A1 DNA sequence |
| 06/11/1986 | EP0183876A1 Monoclonal antibodies for endotoxin core and their use |
| 06/11/1986 | EP0183776A1 A process for isolating a substantially insoluble polypeptide using non-ionic detergents. |
| 06/10/1986 | US4594325 High fusion frequency fusible lymphoblastoid cell line |
| 06/10/1986 | US4594323 Extrachromosomal element |
| 06/10/1986 | US4594318 Isolation and localization of DNA segments |
| 06/10/1986 | CN85106190A Hepatitis b virus surface antigen and production thereof |
| 06/10/1986 | CA1205764A1 Cloning vectors for polypeptide expression in microbial hosts |
| 06/05/1986 | WO1986003227A1 An assay for nucleic acid sequences, particularly genetic lesions |
| 06/05/1986 | WO1986003226A1 Transmissible, mammalian genes associated with tumor metastasis |
| 06/05/1986 | WO1986003225A1 cDNA CLONES CODING FOR POLYPEPTIDES EXHIBITING HUMAN GRANULOCYTE MACROPHAGE AND EOSINOPHIL CELLULAR GROWTH FACTOR ACTIVITY |
| 06/05/1986 | WO1986003223A1 Onco-fetal specific monoclonal antibodies, methods of preparation and use |
| 06/05/1986 | WO1986003123A1 Novel non-reverting salmonella live vaccines |
| 06/04/1986 | EP0183571A2 Cosmid vectors |
| 06/04/1986 | EP0183469A1 Phage resistant E. Coli bacterium and method for making the same |
| 06/04/1986 | EP0183350A2 DNA Encoding human colony stimulating factor, peptide encoded thereby,vectors and transformed hosts containing such DNA, and the production of all thereof |
| 06/04/1986 | EP0183272A2 Vector capable of efficient gene expression and utilization of such vector |
| 06/04/1986 | EP0183198A1 A method for purifying a physiologically active substance produced by recombinant DNA technique |
| 06/04/1986 | EP0183175A1 Coryneform bacteria carrying recombinant DNA and a process for producing aromatic amino acids using said bacteria |
| 06/04/1986 | EP0183071A2 Regulatory region for heterologous gene expression in yeast |
| 06/04/1986 | EP0183070A2 Transformation of yeasts of the genus pichia |
| 06/04/1986 | EP0183006A2 A recombinant DNA-molecule, coryneform bacteria carrying recombinant DNA and process for producing an aromatic amino acid by using the same |
| 06/04/1986 | EP0182838A1 Eukarygotic hybrid vectors and preparation of polypeptides |
| 06/03/1986 | US4593003 Using Pseudomonas |
| 06/03/1986 | US4593002 Insertion of nucleotide into virus |
| 06/03/1986 | CA1205400A1 Hla typing method and cdna probes used therein |
| 05/28/1986 | EP0182636A2 Vectors for high-level gene expression |
| 05/28/1986 | EP0182634A2 Diagnostic methods employing antibodies |
| 05/28/1986 | EP0182562A2 Process for a thermo-inducible gene expression in Gram positive bacteria, Bacillus subtilis strains containing plasmids which induce such an expression and portable vector systems |
| 05/28/1986 | EP0182495A1 Immunoassay means and methods useful in human native prothrombin and human abnormal prothrombin determinations |
| 05/28/1986 | EP0182467A2 Human hybridoma fusion partner for production of human monoclonal antibodies |
| 05/28/1986 | EP0182448A2 Production of factor VIII and related products |
| 05/28/1986 | EP0182383A1 Process for the preparation of oligo- and polydeoxyribonucleotides |
| 05/28/1986 | EP0181930A1 Ltr vectors, methods of preparation and use |
| 05/27/1986 | US4591564 Transferase enzymes which modify the 3'-termini of ribonucleic acid and methods |
| 05/27/1986 | US4591562 Genetic engineering, incorporating recombinant plasmid dna derivedfrom bacillus |
| 05/27/1986 | US4591504 Human leucocyte pepsin-like enzyme as a therapeutic agent for treating allergic disorders and immune complex diseases |
| 05/27/1986 | CA1205030A1 Process for the separation of lymphocyte activating factors from incubation media of cell populations, particularly from a granulocyte-macrophagic line, by an antigen-antibody reaction utilizing anti-mdp antibodies |
| 05/27/1986 | CA1205027A1 Chimeric plasmids that replicate in bacteria and yeast and microorganisms transformed therewith |
| 05/27/1986 | CA1205026A1 Expression of polypeptides in yeast |
| 05/27/1986 | CA1205025A1 Cloning and expression vector and yeast transformed by said vector |
| 05/22/1986 | WO1986002948A1 Polynucleotide probes |
| 05/22/1986 | WO1986002947A1 Human lysozyme synthesizing gene |
| 05/22/1986 | WO1986002929A1 Nucleotide analogs for nucleic acid labeling and detection |
| 05/21/1986 | EP0181634A2 Synthetic gene for human lysozyme |
| 05/21/1986 | EP0181524A2 Novel lymphokine |
| 05/20/1986 | US4590163 Broad host range DNA cloning system for gram-negative bacteria |
| 05/20/1986 | US4590162 Inserting foreign dna into chromosome of gramnegative bacterium |
| 05/20/1986 | US4590159 Incorporate mutant in genes |
| 05/20/1986 | US4589987 Separating animal cells from a liquid culture |
| 05/20/1986 | CA1204682A1 Adaptors, and synthesis and cloning of proinsulin genes |
| 05/20/1986 | CA1204681A1 Method and vector organism for controlled accumulation of cloned heterologous gene products in bacillus subtilis ii |