Patents
Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210)
08/1985
08/13/1985US4535060 Inhibition resistant 5-enolpyruvyl-3-phosphoshikimate synthetase, production and use
08/13/1985US4535058 Characterization of oncogenes and assays based thereon
08/13/1985US4535057 Immunocapturing, with insoluble matrtix containing antibody against antigen
08/07/1985EP0151102A2 Expression of human alpha-1-antitrypsin in yeast
08/07/1985EP0151030A2 Tumor specific monoclonal antibodies
08/07/1985EP0151001A2 Nonradiometric polynucleotide probes
08/07/1985EP0150895A1 Preparation of cloning vectors for use in streptomyces, escherichia coli and related organisms
08/07/1985EP0150735A2 Protein composition exhibiting coagulation activity and method for the preparation thereof
08/07/1985EP0150572A1 Microbial expression of type 1 transforming growth factor, polypeptide analogs thereof and hybrid EGF/TGF polypeptides
08/07/1985EP0150309A2 Hybridoma antibody
08/06/1985US4533496 Method of isolating monoclonal antibodies from hybridoma cultures
08/01/1985WO1985003297A1 Deoxyribonucleic acid molecules useful as probes for detecting deleterious genes incorporated into chromosomal dna
07/1985
07/31/1985EP0150126A2 The synthesis of protein with an identification peptide
07/31/1985EP0149936A2 Mutants of Escherichia Coli capable of secreting periplasmic proteins in the extracellular space, their obtention and application to the preparation of beta-lactamases or hybrid proteins of beta-lactamases
07/31/1985EP0149915A2 Starch utilization by gram negative microorganisms
07/30/1985US4532220 Assays for the determination of carcinogenicity
07/30/1985US4532211 Coliform bacillus having a gene for the production of staphylokinase and a process for production of staphylokinase therewith
07/30/1985US4532207 Process for the preparation of polypeptides utilizing a charged amino acid polymer and exopeptidase
07/30/1985CA1191101A1 Asporogenic mutant of bacillus subtilis useful as a host in a host vector system
07/30/1985CA1191100A1 Asporogenic mutant of bacillus subtilis useful as a host in a host vector system
07/30/1985CA1191099A1 Amylase-negative, asporogenous mutant of bacillus subtilis useful as a host in a host vector system
07/30/1985CA1191097A1 Plasmid cloning vector for bacillus subtilis
07/24/1985EP0149548A2 Nucleic acid encoding a T-cell antigen receptor polypeptide
07/24/1985EP0149547A2 Neoplastic diagnosis by detection of gene rearrangements
07/24/1985EP0149539A2 Mutant strains deficient in L-serine deaminase activity and use thereof
07/24/1985EP0149430A1 Process for preparation of chimerical DNA
07/24/1985EP0149241A2 DNA base sequence containing regions involved in the production and secretion of a protein, recombinant DNA including the whole or a part of the DNA base sequence, and method of producing proteins by use of the recombinant DNA
07/24/1985EP0149162A2 Variety of Bacillus thuringiensis effective against Coleoptera and an insecticidally active preparation obtainable therefrom, or a toxine, and their use to combate Coleoptera
07/24/1985EP0149040A2 Modified live pseudorabies viruses, vaccines for pseudorabies disease containing same, methods for production of same and methods for use of same
07/24/1985EP0148922A1 Hybrid dna synthesis of epidermal growth factor
07/24/1985EP0148845A1 Cloning vector, method of constructing such, and method of concentrating and purifying product proteins produced by the cloning vector
07/23/1985US4530904 Method for conferring bacteriophage resistance to bacteria
07/23/1985US4530901 Recombinant DNA molecules and their use in producing human interferon-like polypeptides
07/23/1985CA1190873A1 Recombinant monoclonal antibodies
07/23/1985CA1190838A1 Homogeneous nucleic acid hybridization diagnostics by non-radiative energy transfer
07/18/1985WO1985003133A1 Immunoassay for biologically active human interferon-gamma
07/18/1985WO1985003132A1 Cytokeratin tumor markers and assays for their detection
07/18/1985WO1985003086A1 Process for preparing sugar-added polypeptides
07/18/1985WO1985003085A1 Process for the production of mixotrophic tissue cultures and herbicide-resistant plants
07/18/1985WO1985003079A1 HUMAN ERYTHROPOIETIN cDNA CLONES
07/17/1985EP0148668A2 Plasmid cloning and expression vectors for a protein in a microorganism, comprising at least the expression promotor of beta-glucosidase in the yeasts; these vectors containing microorganisms; fermentation process and enzymes so obtained
07/17/1985EP0148605A2 Production of erythropoietin
07/17/1985EP0148552A1 Streptomyces expression sequence and methods for expressing DNA sequences in streptomyces
07/16/1985US4529700 Hybridoma cells secreting a monoclonal antibody specific for 5-bromo and 5-iodoeoxyuridine and reagents for measuring cellular proliferation
07/16/1985US4529695 Producing a polypeptide
07/16/1985US4528773 Method for producing genes conferring resistance to herbicides, growth regulators or other chemical agents in vascular plants
07/16/1985CA1190491A1 Plasmid and production thereof
07/16/1985CA1190490A1 Method for stabilizing and selecting recombinant dna containing host cells
07/10/1985EP0148075A2 Anti-PGE specific monoclonal antibodies, their preparation and their biological applications
07/10/1985EP0147819A2 Purification of recombinant interleukin-2
07/09/1985US4528266 Method of inserting unique DNA sequences into DNA vectors
07/04/1985WO1985002909A1 Anti-idiotype antibodies induced by synthetic polypeptides
07/03/1985EP0147198A2 Fermentation processes and their products
07/03/1985EP0147178A2 Expression plasmids for improved production of heterologous protein in bacteria
07/03/1985EP0147175A2 Novel basic polypeptides and a method of producing thereof
07/03/1985EP0147145A2 Streptomycete host cells of reduced restriction activity
07/03/1985EP0147118A1 Monoclonal antibody
07/03/1985EP0146929A2 Microorganism of the genus Serratia containing a hybrid plasmid and process for preparing the same
07/03/1985EP0146903A2 Production of a vector encoding a novel hybrid interferon species
07/03/1985EP0146901A1 A promotor and use thereof
07/03/1985EP0146785A1 Process for the preparation of protease inhibitors
07/03/1985EP0146743A2 Gene fragments derived from human immunoglobulin gene
07/03/1985EP0146627A1 Novel immunoglobulin-coding dna
07/03/1985EP0146589A1 Process for genetic mapping and cross-breeding thereon for plants
07/03/1985EP0146563A1 Immunoassay for human chorionic gonadotropin
06/1985
06/26/1985EP0146462A2 Cloning and expression vectors for gamma interferon, transformed bacterias and process for the preparation of gamma-interferon
06/26/1985EP0146416A1 Vector modified by at least a part if not the whole of gene Lam B and microorganisms transformed with this vector and made capable of synthesizing a determined external membrane protein, encoded by an insert also included in said vector
06/26/1985EP0146413A2 Interferons with novel cysteine pattern
06/26/1985EP0146368A2 Cosmid cloning vectors
06/26/1985EP0146354A2 Recombinant gamma interferons and pharmaceutical compositions containing them
06/26/1985EP0146050A2 Site selective plasminogen activator and method of making and using same
06/26/1985EP0146026A2 DNA encoding rabbit TNF, vector having said DNA inserted thereinto, host transformed with said vector, rabbit TNF polypeptide, and process for production thereof
06/26/1985EP0145949A2 Monoclonal antibody to ovarian and uterine human cancers
06/25/1985CA1189467A1 Stabilizing and selecting recombinant dna host cells
06/25/1985CA1189466A1 Recombinant dna techniques
06/20/1985WO1985002628A1 Nucleic acid hybridization assay
06/20/1985WO1985002625A1 Feline leukemia virus vaccine
06/20/1985WO1985002624A1 VECTOR FOR THE CLONING AND EXPRESSION OF gamma-INTERFERON, TRANSFORMED BACTERIA AND PROCESS FOR THE PREPARATION OF gamma-INTERFERON
06/20/1985WO1985002610A1 Production of erythropoietin
06/19/1985EP0145486A2 Microbiological process
06/19/1985EP0145390A2 A method for producing non-glycosylated human interleukin-2 protein
06/19/1985EP0145356A2 Method of assay of DNA or RNA from virus particles
06/19/1985EP0145338A1 Octopine T-DNA promoters
06/19/1985EP0145333A2 Candida albicans cytoplasmic antigen, monoclonal antibodies against it and methods for the preparation
06/19/1985EP0145174A1 Novel, physiologically active polypeptides and production method thereof
06/19/1985EP0145156A1 Expression vectors, host cells comprising such vectors and methods of making desired compounds using such cells
06/19/1985EP0145111A1 DNA sequence coding for a plant toxin of the ricin type, or a portion thereof
06/18/1985US4524025 Hybridoma cell lines and monoclonal antibodies to theophylline
06/12/1985EP0144064A2 Method for producing interferons
06/12/1985EP0143841A1 Hybrid viral plasmid and microorganisms containing same.
06/12/1985EP0143836A1 Expression and secretion vectors and method of constructing vectors
06/12/1985EP0143834A1 Heat regulated production of selected and fused proteins in yeast
06/12/1985EP0143821A1 Production of catechol 2,3-oxygenase by means of yeasts, plasmide for the implementation thereof and application
06/12/1985EP0143807A1 Method for immobilizing proteins or enzymes
06/11/1985CA1188642A1 Human nonsecretory plasmacytoid cell line
06/06/1985WO1985002415A1 Non radioactive probe and process for the characterization of a dtermined nucleotide sequence and means for the production of said non radioactive probe
06/06/1985WO1985002414A1 Method of catalyzing chemical reactions
06/05/1985EP0143648A2 Process of preparing a component of a cell growth medium
06/05/1985EP0143615A2 Repetitive sequences derived from certain nitrogen fixing bacterial species
06/05/1985EP0143367A2 Method for production of monoclonal antibodies for cancer diagnosis and therapy