Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210) |
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08/13/1985 | US4535060 Inhibition resistant 5-enolpyruvyl-3-phosphoshikimate synthetase, production and use |
08/13/1985 | US4535058 Characterization of oncogenes and assays based thereon |
08/13/1985 | US4535057 Immunocapturing, with insoluble matrtix containing antibody against antigen |
08/07/1985 | EP0151102A2 Expression of human alpha-1-antitrypsin in yeast |
08/07/1985 | EP0151030A2 Tumor specific monoclonal antibodies |
08/07/1985 | EP0151001A2 Nonradiometric polynucleotide probes |
08/07/1985 | EP0150895A1 Preparation of cloning vectors for use in streptomyces, escherichia coli and related organisms |
08/07/1985 | EP0150735A2 Protein composition exhibiting coagulation activity and method for the preparation thereof |
08/07/1985 | EP0150572A1 Microbial expression of type 1 transforming growth factor, polypeptide analogs thereof and hybrid EGF/TGF polypeptides |
08/07/1985 | EP0150309A2 Hybridoma antibody |
08/06/1985 | US4533496 Method of isolating monoclonal antibodies from hybridoma cultures |
08/01/1985 | WO1985003297A1 Deoxyribonucleic acid molecules useful as probes for detecting deleterious genes incorporated into chromosomal dna |
07/31/1985 | EP0150126A2 The synthesis of protein with an identification peptide |
07/31/1985 | EP0149936A2 Mutants of Escherichia Coli capable of secreting periplasmic proteins in the extracellular space, their obtention and application to the preparation of beta-lactamases or hybrid proteins of beta-lactamases |
07/31/1985 | EP0149915A2 Starch utilization by gram negative microorganisms |
07/30/1985 | US4532220 Assays for the determination of carcinogenicity |
07/30/1985 | US4532211 Coliform bacillus having a gene for the production of staphylokinase and a process for production of staphylokinase therewith |
07/30/1985 | US4532207 Process for the preparation of polypeptides utilizing a charged amino acid polymer and exopeptidase |
07/30/1985 | CA1191101A1 Asporogenic mutant of bacillus subtilis useful as a host in a host vector system |
07/30/1985 | CA1191100A1 Asporogenic mutant of bacillus subtilis useful as a host in a host vector system |
07/30/1985 | CA1191099A1 Amylase-negative, asporogenous mutant of bacillus subtilis useful as a host in a host vector system |
07/30/1985 | CA1191097A1 Plasmid cloning vector for bacillus subtilis |
07/24/1985 | EP0149548A2 Nucleic acid encoding a T-cell antigen receptor polypeptide |
07/24/1985 | EP0149547A2 Neoplastic diagnosis by detection of gene rearrangements |
07/24/1985 | EP0149539A2 Mutant strains deficient in L-serine deaminase activity and use thereof |
07/24/1985 | EP0149430A1 Process for preparation of chimerical DNA |
07/24/1985 | EP0149241A2 DNA base sequence containing regions involved in the production and secretion of a protein, recombinant DNA including the whole or a part of the DNA base sequence, and method of producing proteins by use of the recombinant DNA |
07/24/1985 | EP0149162A2 Variety of Bacillus thuringiensis effective against Coleoptera and an insecticidally active preparation obtainable therefrom, or a toxine, and their use to combate Coleoptera |
07/24/1985 | EP0149040A2 Modified live pseudorabies viruses, vaccines for pseudorabies disease containing same, methods for production of same and methods for use of same |
07/24/1985 | EP0148922A1 Hybrid dna synthesis of epidermal growth factor |
07/24/1985 | EP0148845A1 Cloning vector, method of constructing such, and method of concentrating and purifying product proteins produced by the cloning vector |
07/23/1985 | US4530904 Method for conferring bacteriophage resistance to bacteria |
07/23/1985 | US4530901 Recombinant DNA molecules and their use in producing human interferon-like polypeptides |
07/23/1985 | CA1190873A1 Recombinant monoclonal antibodies |
07/23/1985 | CA1190838A1 Homogeneous nucleic acid hybridization diagnostics by non-radiative energy transfer |
07/18/1985 | WO1985003133A1 Immunoassay for biologically active human interferon-gamma |
07/18/1985 | WO1985003132A1 Cytokeratin tumor markers and assays for their detection |
07/18/1985 | WO1985003086A1 Process for preparing sugar-added polypeptides |
07/18/1985 | WO1985003085A1 Process for the production of mixotrophic tissue cultures and herbicide-resistant plants |
07/18/1985 | WO1985003079A1 HUMAN ERYTHROPOIETIN cDNA CLONES |
07/17/1985 | EP0148668A2 Plasmid cloning and expression vectors for a protein in a microorganism, comprising at least the expression promotor of beta-glucosidase in the yeasts; these vectors containing microorganisms; fermentation process and enzymes so obtained |
07/17/1985 | EP0148605A2 Production of erythropoietin |
07/17/1985 | EP0148552A1 Streptomyces expression sequence and methods for expressing DNA sequences in streptomyces |
07/16/1985 | US4529700 Hybridoma cells secreting a monoclonal antibody specific for 5-bromo and 5-iodoeoxyuridine and reagents for measuring cellular proliferation |
07/16/1985 | US4529695 Producing a polypeptide |
07/16/1985 | US4528773 Method for producing genes conferring resistance to herbicides, growth regulators or other chemical agents in vascular plants |
07/16/1985 | CA1190491A1 Plasmid and production thereof |
07/16/1985 | CA1190490A1 Method for stabilizing and selecting recombinant dna containing host cells |
07/10/1985 | EP0148075A2 Anti-PGE specific monoclonal antibodies, their preparation and their biological applications |
07/10/1985 | EP0147819A2 Purification of recombinant interleukin-2 |
07/09/1985 | US4528266 Method of inserting unique DNA sequences into DNA vectors |
07/04/1985 | WO1985002909A1 Anti-idiotype antibodies induced by synthetic polypeptides |
07/03/1985 | EP0147198A2 Fermentation processes and their products |
07/03/1985 | EP0147178A2 Expression plasmids for improved production of heterologous protein in bacteria |
07/03/1985 | EP0147175A2 Novel basic polypeptides and a method of producing thereof |
07/03/1985 | EP0147145A2 Streptomycete host cells of reduced restriction activity |
07/03/1985 | EP0147118A1 Monoclonal antibody |
07/03/1985 | EP0146929A2 Microorganism of the genus Serratia containing a hybrid plasmid and process for preparing the same |
07/03/1985 | EP0146903A2 Production of a vector encoding a novel hybrid interferon species |
07/03/1985 | EP0146901A1 A promotor and use thereof |
07/03/1985 | EP0146785A1 Process for the preparation of protease inhibitors |
07/03/1985 | EP0146743A2 Gene fragments derived from human immunoglobulin gene |
07/03/1985 | EP0146627A1 Novel immunoglobulin-coding dna |
07/03/1985 | EP0146589A1 Process for genetic mapping and cross-breeding thereon for plants |
07/03/1985 | EP0146563A1 Immunoassay for human chorionic gonadotropin |
06/26/1985 | EP0146462A2 Cloning and expression vectors for gamma interferon, transformed bacterias and process for the preparation of gamma-interferon |
06/26/1985 | EP0146416A1 Vector modified by at least a part if not the whole of gene Lam B and microorganisms transformed with this vector and made capable of synthesizing a determined external membrane protein, encoded by an insert also included in said vector |
06/26/1985 | EP0146413A2 Interferons with novel cysteine pattern |
06/26/1985 | EP0146368A2 Cosmid cloning vectors |
06/26/1985 | EP0146354A2 Recombinant gamma interferons and pharmaceutical compositions containing them |
06/26/1985 | EP0146050A2 Site selective plasminogen activator and method of making and using same |
06/26/1985 | EP0146026A2 DNA encoding rabbit TNF, vector having said DNA inserted thereinto, host transformed with said vector, rabbit TNF polypeptide, and process for production thereof |
06/26/1985 | EP0145949A2 Monoclonal antibody to ovarian and uterine human cancers |
06/25/1985 | CA1189467A1 Stabilizing and selecting recombinant dna host cells |
06/25/1985 | CA1189466A1 Recombinant dna techniques |
06/20/1985 | WO1985002628A1 Nucleic acid hybridization assay |
06/20/1985 | WO1985002625A1 Feline leukemia virus vaccine |
06/20/1985 | WO1985002624A1 VECTOR FOR THE CLONING AND EXPRESSION OF gamma-INTERFERON, TRANSFORMED BACTERIA AND PROCESS FOR THE PREPARATION OF gamma-INTERFERON |
06/20/1985 | WO1985002610A1 Production of erythropoietin |
06/19/1985 | EP0145486A2 Microbiological process |
06/19/1985 | EP0145390A2 A method for producing non-glycosylated human interleukin-2 protein |
06/19/1985 | EP0145356A2 Method of assay of DNA or RNA from virus particles |
06/19/1985 | EP0145338A1 Octopine T-DNA promoters |
06/19/1985 | EP0145333A2 Candida albicans cytoplasmic antigen, monoclonal antibodies against it and methods for the preparation |
06/19/1985 | EP0145174A1 Novel, physiologically active polypeptides and production method thereof |
06/19/1985 | EP0145156A1 Expression vectors, host cells comprising such vectors and methods of making desired compounds using such cells |
06/19/1985 | EP0145111A1 DNA sequence coding for a plant toxin of the ricin type, or a portion thereof |
06/18/1985 | US4524025 Hybridoma cell lines and monoclonal antibodies to theophylline |
06/12/1985 | EP0144064A2 Method for producing interferons |
06/12/1985 | EP0143841A1 Hybrid viral plasmid and microorganisms containing same. |
06/12/1985 | EP0143836A1 Expression and secretion vectors and method of constructing vectors |
06/12/1985 | EP0143834A1 Heat regulated production of selected and fused proteins in yeast |
06/12/1985 | EP0143821A1 Production of catechol 2,3-oxygenase by means of yeasts, plasmide for the implementation thereof and application |
06/12/1985 | EP0143807A1 Method for immobilizing proteins or enzymes |
06/11/1985 | CA1188642A1 Human nonsecretory plasmacytoid cell line |
06/06/1985 | WO1985002415A1 Non radioactive probe and process for the characterization of a dtermined nucleotide sequence and means for the production of said non radioactive probe |
06/06/1985 | WO1985002414A1 Method of catalyzing chemical reactions |
06/05/1985 | EP0143648A2 Process of preparing a component of a cell growth medium |
06/05/1985 | EP0143615A2 Repetitive sequences derived from certain nitrogen fixing bacterial species |
06/05/1985 | EP0143367A2 Method for production of monoclonal antibodies for cancer diagnosis and therapy |