Patents
Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210)
08/1981
08/26/1981EP0034307A2 Method for the production of human leucozyte interferon
08/26/1981EP0034306A2 Method for producing human fibroblast interferon
08/12/1981EP0033702A2 2-Nitronaphthofurane derivatives, their preparation and their use, in particular as cell-growth regulators
08/12/1981EP0033579A2 Hybrid cell line for producing monoclonal antibody to a human monocyte antigen, antibody, and methods
08/12/1981EP0033578A2 Hybrid cell line for producing monoclonal antibody to a human T cell antigen, antibody, and methods
08/11/1981US4283489 Purification of nucleotide sequences suitable for expression in bacteria
07/1981
07/29/1981EP0032675A2 Microbiologically produced polypeptide having the amino acid sequence of monkey proinsulin, DNA and plasmids coding for this sequence, microorganisms containing this genetic information, and process for their production
07/28/1981CA1105859A1 Method of facilitating genetic exchange in streptomyces by protoplastfusion
07/22/1981EP0032238A2 Recombinant bacteriophage for heterologous cloning of bacillus microorganisms and method for its production
07/21/1981CA1105403A1 Method of obtaining streptomyces protoplasts capable of efficient cell regeneration
07/15/1981EP0032134A2 DNA sequences, recombinant DNA molecules and processes for producing human interferon-alpha like polypeptides
07/14/1981US4278765 Method for preparing strains which produce aminoacids
07/14/1981US4278662 Attenuated influenza type A virus vaccine
07/09/1981WO1981001849A1 Purified human prostate antigen
06/1981
06/24/1981EP0030815A2 Hybrid cell line for producing monoclonal antibody to a human prothymocyte antigen, antibody, method of preparation of this antibody, diagnostic and therapeutic uses, and pharmaceutical compositions comprising this antibody
06/24/1981EP0030814A2 Hybrid cell line for producing monoclonal antibody to a human early thymocyte antigen, antibody, method of preparation of this antibody, diagnostic and therapeutic uses and pharmaceutical compositions comprising this antibody
06/24/1981EP0030727A2 Method for producing L-valine by fermentation and method for producing a new microorganism of the genus Escherichia
06/17/1981EP0030450A2 Hybrid cell line for producing complement-fixing, monoclonal antibody to human suppressor T cells, antibody, method of preparation of this antibody, diagnostic and therapeutic uses and pharmaceutical compositions comprising this antibody
06/17/1981EP0030449A2 Hybrid cell line for producing monoclonal antibody to human thymocyte antigen, antibody, method of preparation of this antibody, diagnostic and therapeutic uses and pharmaceutical compositions comprising this antibody
06/17/1981EP0030391A2 Method for producing L-glutamic acid by fermentation and a method for producing a new microorganism
06/16/1981US4273875 Plasmid and process of isolating same
06/16/1981CA1103157A1 Method of producing antibodies
06/16/1981CA1103156A1 Method of producing tumor antibodies
06/10/1981EP0029893A2 Process for concentration of tumor-inhibiting substances
06/03/1981EP0029497A1 Asporogenous mutant of bacillus subtilis and process for the use thereof as host component of a HV1 system
06/02/1981US4271145 Process for producing antibodies to hepatitis virus and cell lines therefor
05/1981
05/20/1981EP0028902A1 Method for the preferential formation of hybrid cells making a desired antibody
04/1981
04/30/1981WO1981001153A1 Eucaryote cells having a certain and concentration
04/29/1981EP0027662A1 Eucaryotic cells and eucaryotic protoplasts with an amount of naked DNA introduced by lipid vesicles, process for their preparation and their use in the preparation of gene products
04/29/1981EP0027657A2 Process for producing antibodies to hepatitis virus and cell lines therefor
04/28/1981US4264737 Method of making genetically stable mutants of vibrio cholerae
04/28/1981US4264731 DNA Joining method
04/22/1981EP0027249A1 Process for the preparation of influenza A virus vaccinating strains, vaccinating strain and vaccine containing it
04/21/1981US4263403 Method of extracting uranium from sea water
04/15/1981EP0026849A1 Process for producing anthracycline glycosides
04/08/1981EP0026598A1 DNA transfer vectors for human proinsulin and human pre-proinsulin, microorganisms transformed thereby, and processes involving such substances
03/1981
03/31/1981US4259444 Microorganisms having multiple compatible degradative energy-generating plasmids and preparation thereof
03/31/1981CA1098463A1 Microbial production of poly-(d-3-hydroxybutyric acid)
03/11/1981EP0024956A2 Genetically attenuated bacterial vaccines with multiple mutations of the same phenotype, method of preparing them and bacterial strains used in them
03/05/1981WO1981000577A1 Nucleotidic sequence coding the surface antigen of the hepatitis b virus,vector containing said nucleotidic sequence,process allowing the obtention thereof and antigen obtained thereby
02/1981
02/11/1981EP0023882A2 Plasmid vectors, plasmids containing genes for alkaline phosphatases and bacteria containing the latter, their preparation and use
02/10/1981CA1095407A1 Preparation for the treatment of herpes zoster and other herpes infections, as well as method for manufacture thereof
02/04/1981EP0023397A1 Heteropolysaccharide; process and microorganism for producing it
01/1981
01/22/1981WO1981000114A1 Microbial expression of quasi-synthetic genes
01/21/1981EP0022685A1 Vectors for the transfer and the expression of genetic material and their uses
01/14/1981EP0022242A2 Cloning vehicle, method of constructing it, method of producing human growth hormone and bacteria therefor
01/07/1981EP0021468A1 Plasmid, host containing it, its preparation and use
01/06/1981US4242832 Process for preparing monokaryons by dedikaryotizing dikaryotic strains of Basidiomycetes
01/06/1981CA1093000A1 Polyribonucleotides capable of promoting the genesis of leucocytes and blood platelets
12/1980
12/10/1980EP0020290A1 Process for the specific splitting-off of protein sequences from proteins
12/10/1980EP0020251A2 DNA transfer vector, host transformed with it, vaccine, and their production
12/10/1980EP0020147A1 A DNA transfer vector for human pre-growth hormone, a microorganism transformed thereby, and a method of cloning therefor
12/10/1980EP0019877A1 Method of preparing a microorganism, harboring a plasmid, with stabilized characteristics, and microorganism obtained in this manner
12/09/1980US4238567 Process for producing food proteins from Trichoderma Album
12/02/1980US4237228 High yield
12/02/1980US4237224 Genetic engineering
11/1980
11/27/1980WO1980002504A1 Genetically attenuated bacterial vaccines with multiple mutations of the same phenotype
11/25/1980US4235871 By forming an emulsion, evaporation of the organic solvent to form a gel
11/12/1980EP0018795A2 Monoclonal-antibody-producing hybrid cell line, antibody and method of preparing it, therapeutic composition containing it and its diagnostic and therapeutic uses
11/12/1980EP0018794A2 Monoclonal antibody to human helper T cells, method of preparing it, hybrid cell line producing it, its diagnostic and therapeutic uses and diagnostic and therapeutic compositions comprising it
10/1980
10/29/1980EP0018154A2 Vibrio cholerae mutants, vaccine comprising them, method for preparing a subunit therefrom and composition comprising it
10/15/1980EP0017381A2 Monoclonal antibody to human T cells, method for preparing it, hybrid cell line producing it, therapeutic composition comprising it and diagnostic method using it
09/1980
09/23/1980US4224408 Deoxyribonucleic acid synthesis using binding protein
09/17/1980EP0015308A1 Process for the selective degradation of side chains of steroid compounds and for the preparation of the appropriate defective microorganism mutants and microorganism strains
09/03/1980EP0015101A2 Method and apparatus for selecting cheese starter cultures
08/1980
08/20/1980EP0014519A2 Cell lines, process for preparing them and process for producing antibodies
08/19/1980US4218534 Cheesemaking
08/06/1980EP0013830A2 Stable high copy number plasmids, their formation and use in protein production
08/06/1980EP0013828A1 Recombinant DNA, hosts transformed with it and processes for the preparation of polypeptides
06/1980
06/25/1980EP0012494A1 A DNA transfer vector, a microorganism modified by said vector and the synthesis of a eucaryotic protein by the modified microorganism
06/11/1980EP0012078A1 Vector allowing the insertion of a procaryotic or eucaryotic gene, and the excretion of the expressed protein
05/1980
05/28/1980EP0011562A1 Saccharomyces cer. transformed by a plasmid
05/28/1980EP0011560A2 Vectors appropriate for the insertion in their genomes of fragments of foreign DNA, in each of the possible translational phases, and means for their preparation
05/20/1980CA1077870A1 Process for the production of insulin by genetically transformed fungal cells
05/15/1980WO1980000921A1 Aqueous micro emulsions of organic substances
04/1980
04/16/1980EP0009930A1 Recombinant DNA, method for preparing it and production of foreign proteins by unicellular hosts containing it
03/1980
03/04/1980US4191745 Active principle pox and-or parapox virus
02/1980
02/26/1980US4190649 Polyribonucleotides capable of promoting the genesis of leucocytes and blood platelets
02/26/1980US4190495 Modified microorganisms and method of preparing and using same
01/1980
01/15/1980CA1069821A1 Method for the preparation of avirulent viral mutant from the aujeszky's virus
01/10/1980WO1980000030A1 Method of making a selected protein
01/09/1980EP0006694A2 Method of making a selected protein
01/09/1980EP0006692A1 Streptomyces plasmids and microorganisms containing them, their use as vectors for nucleic acid and a process for the incorporation of nucleic acids into cellular systems
12/1979
12/27/1979WO1979001169A1 Streptomyces plasmids and their use as vectors for the incorporation of nucleic acid into cellular systems
10/1979
10/31/1979EP0004913A1 Process for the selective degradation of side chains of steroids and for the preparation of the appropriate defective blocked microorganism mutants and new microorganism strains
10/30/1979US4172764 Process for obtaining hybrid strains of yeasts
10/23/1979US4172124 Method of producing tumor antibodies
09/1979
09/19/1979EP0004223A1 Process for the preparation of lipidic capsules containing a biologically active compound, products obtained by this process as well as their utilisation
07/1979
07/26/1979WO1979000467A1 Process for producing gene products of plasmid dna
07/25/1979EP0003062A2 Plasmids, bacteria and gene products of plasmid DNA, processes for preparing them
06/1979
06/26/1979US4159226 Culturing
06/26/1979US4159225 Method of producing a stable monokaryotic mycelium of Coriolus versicolor and its use in polysaccharide production
06/13/1979EP0002322A2 Improved Triester process for the synthesis of oligonucleotides
05/1979
05/16/1979EP0001931A2 Synthetic DNA, process for preparing it and recombinant microbial cloning vehicle containing such DNA
05/16/1979EP0001930A2 Method for polypeptide production involving expression of a heterologous gene, recombinant microbial cloning vehicle containing said gene and bacterial culture transformed by said cloning vehicle
05/16/1979EP0001929A2 Plasmid for transforming bacterial host to render it capable of polypeptide expression
02/1979
02/13/1979US4139346 Nucleic acid and protein binding paper
02/06/1979US4138291 Obtaining bacteria strain which can convert carbon source into poly-(d-3-hydroxybutyric acid)
12/1978
12/19/1978US4130395 Process and apparatus for detection of specific biological factors by means of osmotic hemolysis
09/1978
09/26/1978CA1039186A1 Temperature sensitive and non-pathogenic bovine adenovirus