Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210) |
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02/22/1984 | EP0101273A2 Production of biological products using resting cells |
02/22/1984 | EP0101039A2 Monoclonal antibody, method of producing the same and use thereof |
02/21/1984 | US4433140 Primer in enzymatic synthesis of dna |
02/21/1984 | US4432751 Monoclonal antibodies against lens epithelial cells and preventing proliferation of remnant lens epithelial cells after extracapsular extraction |
02/21/1984 | CA1162480A1 Veterinary vaccines |
02/16/1984 | WO1984000560A1 Molecular cloning of the gene for human anti-haemophilic factor ix |
02/16/1984 | WO1984000466A1 Broad spectrum plant protection from pathogens |
02/15/1984 | EP0100691A1 Process for the in vitro production of vesicular-arbuscular endomycorrhizal fungi |
02/15/1984 | EP0100561A1 Yeast hybrid vectors and their use for the production of polypeptides |
02/15/1984 | EP0100521A2 Process for the production of a herpes antigen, appropriate means therefor and a process for its production, and the use of this antigen |
02/14/1984 | US4431740 Genetic engineering |
02/14/1984 | US4431739 Cloning vehicles for heterologous dna coding of somatostatin, haptens, insulin and other polypetides |
02/09/1984 | EP0093121A4 Enhancement of expression of protein synthesis in e. coli. |
02/08/1984 | EP0100254A1 Microorganisms, especially E. coli, transformed with a DNA sequence originating from C. thermocellum, compositions having a cellulolytic activity issued from these microorganisms and process to obtain them |
02/07/1984 | US4430434 Plasmid and its use |
02/07/1984 | US4430432 Cultures, saccharomyces, pichia |
02/07/1984 | US4430430 Cultures, transformants of genus escherichia |
02/07/1984 | US4430428 Composition of matter and process |
02/07/1984 | CA1161736A1 Fluorescent detection of genetic (dna) damage |
02/02/1984 | WO1984000384A1 Method for the performance of a mutagenicity test |
02/02/1984 | WO1984000381A1 Genetic engineering in procaryotic organism |
02/02/1984 | WO1984000380A1 Vector |
02/01/1984 | EP0099871A1 Separation of plasma proteins from cell culture systems |
01/31/1984 | US4428941 Nucleotidic sequence coding the surface antigen of the hepatitis B virus, vector containing said nucleotidic sequence, process allowing the obtention thereof and antigen obtained thereby |
01/25/1984 | EP0099255A2 Method for transforming plant cells |
01/25/1984 | EP0099226A1 Filamentous fungi functional replicating extrachromosomal element |
01/25/1984 | EP0099084A2 Process for the preparation of interferon and expression vehicles therefor |
01/25/1984 | EP0098967A2 Process for the preparation of obligate methylotrophic, foreign DNA expressing bacteria, and appropriate plasmids and host organisms therefor |
01/24/1984 | US4427773 Method for producing L-glutamic acid by fermentation |
01/19/1984 | WO1984000175A1 Micro-organisms, particularly e.coli, transformed by dna sequence originating from c.thermocellum, compositions having a cellulolytic activity issued from said micro-organisms and process for obtaining them |
01/18/1984 | EP0098750A2 Stabilisation of a mutant micro-organism population |
01/18/1984 | EP0098267A1 A method and reagent combination for the diagnosis of microorganisms by sandwich hybridization of nucleic acids |
01/17/1984 | US4426517 With diethylamine |
01/11/1984 | EP0098179A2 Hybridoma cell lines and monoclonal antibodies to theophylline |
01/11/1984 | EP0098162A2 Monoclonal antibodies specific to carcinoembryonic antigen |
01/11/1984 | EP0098118A1 Open reading frame vectors |
01/10/1984 | US4425437 Microbial polypeptide expression vehicle |
01/10/1984 | US4425150 Compositions containing and methods of use of an infectivity-cured Hr plasmid-bearing microorganism |
01/05/1984 | WO1984000037A1 Sensitive tests for malignancies based on dna detection |
01/04/1984 | EP0097518A2 Monoclonal antibody |
01/04/1984 | EP0097373A2 Modified labeled nucleotides and polynucleotides and methods of preparing, utilizing and detecting same |
01/04/1984 | EP0097341A1 Sensitive tests for malignancies based on DNA detection |
12/28/1983 | EP0096910A1 Yeast of the genus Kluyveromyces modified for the expression of preprothaumatin or its various allelic and modified forms or their maturation forms |
12/27/1983 | CA1159381A1 Vectors for the insertion therein of foreign dna fragments, according to any translation phase, and means for their manufacture |
12/22/1983 | WO1983004418A1 A process for the preparation of chymosin |
12/21/1983 | EP0096586A2 Temperature sensitive multicopy plasmids and organisms containing the same, their production and use in protein production |
12/21/1983 | EP0096491A2 Eukaryotic metallothionein promoter system |
12/21/1983 | EP0096430A1 Cloning system for Kluyveromyces species |
12/08/1983 | WO1983004313A1 Human-human hybridomas for neoplasms |
12/08/1983 | WO1983004262A1 Method of producing protein fragments |
12/08/1983 | WO1983004261A1 New cloning and expression vector, yeast transformed by such vector and applications thereof |
12/08/1983 | WO1983004260A1 Human leukocyte pepsin-like enzyme, and a therapeutic agent containing said enzyme as effective ingredient for treating allergic disorder, immune complex disease, and tumor |
12/07/1983 | EP0095986A1 Cloning and expression vector, yeast transformed by this vector and their use |
12/07/1983 | EP0095947A2 Partition proficiency encoded DNA and plasmids incorporating the same for transforming gram-positive organisms |
12/07/1983 | EP0095934A2 Novel bacteriophage and method for breeding thereof |
12/07/1983 | EP0095702A1 Microbially prepared interferon alpha2(Arg), DNA sequence coding for said interferon, microorganisms containing this genetic information and process for their production |
12/07/1983 | EP0095502A1 Human monoclonal antibodies or lymphokines in separation of cells or diagnosis of mammary cancer |
12/06/1983 | US4419450 Plasmid cloning vector for Bacillus subtilis |
12/06/1983 | US4419446 Recombinant DNA process utilizing a papilloma virus DNA as a vector |
11/30/1983 | EP0095452A2 Preparation of DNA sequences and DNA recombinant molecules coding for the cholera toxine units A and B, the products obtained and compositions containing the unit(s) obtained |
11/30/1983 | EP0095361A1 Cloning vectors for expression of exogenous protein |
11/30/1983 | EP0095351A2 A precursor of a C-terminal amidated peptide and production thereof |
11/30/1983 | EP0095350A2 A method of producing human gamma-interferon-like polipeptide |
11/30/1983 | EP0095346A2 Hybrid cell lines producing monoclonal antibodies directed against treponema |
11/29/1983 | US4418194 DNA Fragments for forming plasmids |
11/29/1983 | US4418150 Yeast containing plasmids providing killer characteristics |
11/29/1983 | US4418149 Biosynthesis of functional proteins |
11/24/1983 | WO1983004053A1 The manufacture and expression of large structural genes |
11/24/1983 | WO1983004052A1 New vectors for the expression of the antigenic protein of rabies and application thereof to the preparation of vaccines |
11/24/1983 | WO1983004051A1 Expression of preprothaumatin-like proteins in kluyveromyces yeasts |
11/24/1983 | WO1983004050A1 Cloning system for kluyveromyces species |
11/24/1983 | WO1983004030A1 The manufacture and expression of genes for urogastrone and polypeptide analogs thereof |
11/24/1983 | WO1983004029A1 The manufacture and expression of structural genes |
11/24/1983 | WO1983003971A1 Hybrid proteins |
11/23/1983 | EP0094887A2 Expression vectors for rabies antigenic protein, and their use in the preparation of vaccines |
11/23/1983 | EP0094797A2 Novel cloning vehicles for polypeptide expression in microbial hosts |
11/23/1983 | EP0094506A2 DNA cloning vector TG1, derivatives, products and processes |
11/23/1983 | EP0094428A1 Control of dna sequence transcription. |
11/22/1983 | US4416994 Plasmid pEL7 and related cloning vectors for use in streptomyces and related organisms |
11/22/1983 | CA1157406A1 Purification of nucleotide sequences suitable for expression in bacteria |
11/16/1983 | EP0093948A1 Double stranded vector and process involving said vector |
11/15/1983 | US4415660 Method of making a cloning vector |
11/10/1983 | WO1983003831A1 Novel ice nucleating microorganisms |
11/09/1983 | EP0093619A1 Human tissue plasminogen activator, pharmaceutical compositions containing it, processes for making it, and DNA and transformed cell intermediates therefor |
11/09/1983 | EP0093611A1 Composite plasmid |
11/09/1983 | EP0093436A2 Process for preparing permanent animal and human cell lines, and their use |
11/09/1983 | EP0093121A1 Enhancement of expression of protein synthesis in e. coli |
11/08/1983 | US4414150 Hybrid human leukocyte interferons |
11/02/1983 | EP0093062A1 DNA containing a sequence encoding for a crystal protein or a polypeptide having insecticidal properties, microorganisms transformed with such DNA, compositions containing said crystal proteins, polypeptide or microorganisms |
11/01/1983 | CA1156166A1 Recombinant bacterial plasmids containing the coding sequences of insulin genes |
10/27/1983 | WO1983003679A1 Antibodies having dual specificities, their preparation and uses therefor |
10/27/1983 | WO1983003623A1 CODING DNA FRAGMENTS FOR POLYPEPTIDES CONTAINING AT LEAST ONE ANTIGENIC DETERMINANT OF THE PAPILLOMAVIRUS PARTICULARLY OF THE 1a HPV TYPE AND CORRESPONDING POLYPEPTIDES |
10/26/1983 | EP0092456A1 DNA fragments encoding for polypeptides containing at least an antigenic determinant of Papilloma viruses, notably of the HPV 1A-type, and corresponding polypeptides |
10/26/1983 | EP0092388A2 Cloning vectors |
10/26/1983 | EP0092249A2 Non-A, non-B hepatitis-associated monoclonal antibody and diagnostic reagent |
10/26/1983 | EP0092236A2 A plasmid cloning vector for Bacillus Subtilis |
10/26/1983 | EP0092235A2 Amylase-negative, asporogenous mutant of Bacillus Subtilis useful as a host in a host-vector system |
10/26/1983 | EP0092234A2 Asporogenic mutant of Bacillus Subtilis useful as a host in a host-vector system |
10/26/1983 | EP0092233A2 Asporogenic mutant of Bacillus Subtilis useful as a host in a host-vector system |
10/26/1983 | EP0092183A2 Preservation of foods with non-lactose fermenting Streptococcus lactis subspecies Diacetilactis |