Patents
Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210)
06/1983
06/08/1983EP0080474A1 Detection of malignant tumor cells
06/07/1983US4387162 Hybrid plasmids and microorganisms containing them
06/01/1983EP0080378A2 L-tryptophan-producing microorganisms
05/1983
05/26/1983WO1983001783A1 Control of dna sequence transcription
05/25/1983EP0079739A2 Albumin-based nucleotides, their replication and use, and plasmids for use therein
05/25/1983EP0079696A1 Monoclonal antibodies specific for the human transferrin receptor glycoprotein
05/24/1983US4385117 High ethanol producing derivatives of Thermoanaerobacter ethanolicus
05/24/1983CA1146882A1 Anucleated live e. coli vaccine
05/18/1983EP0079139A1 A method and reagent combination for the identification of microorganisms and the use of sandwich hybridization of nucleic acids therefor
05/11/1983WO1983001628A1 High ethanol producing derivatives of thermoanaerobacter ethanolicus
05/11/1983EP0078537A2 Plasmid pHM 1519
05/10/1983US4383036 Process for the production of human chorionic gonadotropin
05/10/1983US4383035 Process for the production of human luteinizing hormone
05/10/1983US4383034 Process for the production of human follicle-stimulating hormone
05/04/1983EP0078154A2 Plasmids and cells for heterologous expression of metallothioneins and processes for producing and using the metallothionein
05/03/1983US4382028 Separation of plasma proteins from cell culture systems
04/1983
04/28/1983WO1983001459A1 A method and reagent combination for the diagnosis of microorganisms by sandwich hybridization of nucleic acids
04/28/1983WO1983001451A1 Oligonucleotide therapeutic agent and methods of making same
04/27/1983EP0077689A2 Method of gene manipulation using an eukaryotic cell as the host
04/27/1983EP0077670A2 Human immune interferon
04/27/1983EP0077664A2 Recombinant DNA and coliform bacillus having genetic material for the production of staphylokinase, and the production of staphylokinase
04/27/1983EP0077650A2 Cloning vectors
04/27/1983EP0077649A2 Cloning vectors for use in Streptomyces
04/27/1983EP0077569A2 DNA gene
04/27/1983EP0077557A2 Process for the production of plasmid pAC 1
04/27/1983EP0077548A2 Plasmid
04/26/1983US4381295 Monoclonal antibody to human helper T cells and methods of preparing same
04/20/1983EP0077196A2 Aromatic amino acid-producing microorganisms
04/20/1983EP0077109A2 DNA molecules comprising the genes for preprochymosin and its maturation forms, and microorganisms transformed thereby
04/20/1983EP0076953A2 Pseudomonas compositions
04/14/1983WO1983001176A1 Process for the genetic modification of cereals with transformation vectors
04/13/1983EP0076647A2 Culture media for cells originating from the immune system
04/13/1983EP0076489A2 Deoxyribonucleic acids, recombinant deoxyribonucleic acids, hosts containing them, polypeptides and process for their production
04/06/1983EP0076123A1 Method for identifying and characterizing organisms
04/06/1983EP0076037A2 Amplified expression of DNA sequences
04/06/1983EP0075885A1 Microorganisms for the microbiol degradation of obnoxious organic wastes into innocuous materials
04/05/1983CA1144138A1 Mixed phase chromatographic compositions
03/1983
03/31/1983WO1983001073A1 Method for identifying and characterizing organisms
03/30/1983EP0075444A2 Methods and products for facile microbial expression of DNA sequences
03/30/1983EP0075395A2 Products displaying the antigenicity of hepatitis B virus E antigens and methods of producing those antigens
03/23/1983EP0074930A2 Generating method for cutting involute tooth flanks with profile and longitudinal corrections
03/23/1983EP0074808A2 Recombinant method and materials
03/23/1983EP0074553A2 Method of increasing the yield of a product by altering a microorganism
03/22/1983US4377513 Culturing lymph cells in host animals
03/17/1983WO1983000930A1 Lipoprotein lipase suppression by endotoxin-induce mediator (shock assay)
03/17/1983WO1983000810A1 Selective carcinostatic agent
03/16/1983EP0074279A2 Selective anti-tumour agents
03/16/1983EP0073953A2 Monoclonal antibodies to cell surface antigens of human renal cancer
03/15/1983US4376823 Rna, antibiotic resistance
03/15/1983US4376821 Production of human IFN-gamma (immune) interferon
03/09/1983EP0073657A1 Preparation of hepatitis B surface antigen in yeast
03/09/1983EP0073656A2 Preparation of polypeptides in vertebrate cell culture
03/09/1983EP0073646A2 Construction of DNA sequences and their use for microbial production of proteins, in particular human serum albumin
03/09/1983EP0073635A2 Expression vectors
03/09/1983EP0073436A2 Hybrid plasmid and preparation thereof
03/08/1983US4376164 Process for preparing broad host range small plasmid rings as cloning vehicles
03/08/1983CA1142466A1 Cell lines
03/03/1983WO1983000702A1 Enhancement of expression of protein synthesis in e. coli
03/02/1983EP0073062A2 Plasmid, process for its preparation and its use as vector
03/02/1983EP0073029A2 Recombinant plasmid and microorganism containing same
03/02/1983EP0072925A2 T4 DNA fragment as a stabilizer for proteins expressed by cloned DNA
03/01/1983US4375514 Preparation and use of recombinant plasmids containing genes for alkaline phosphatases
02/1983
02/23/1983EP0072752A2 Human nonsecretory plasmacytoid cell line
02/23/1983EP0072656A1 Method for the preparation of improved mutant strain of bordetella bronchiseptica and live attenuated vaccine containing it
02/23/1983EP0072541A2 Human leukocyte interferons, process for their microbial production, intermediates therefor and compositions containing them
02/22/1983US4374927 Genetic engineering in production of proteins or enzymes
02/17/1983WO1983000503A1 Human nonsecretory plasmacytoid cell line
02/17/1983WO1983000437A1 Oral vaccine for immunization against enteric disease
02/16/1983EP0072318A2 Synthesis of human virus antigens by yeast
02/15/1983US4374200 Broad host range small plasmid rings as cloning vehicles
02/15/1983CA1141313A1 Process for the selective side chain degradation of steroid compounds and for the preparation of defective mutants of microorganisms suitable therefor and also new strains of microorganisms (ii)
02/09/1983EP0071486A2 Novel microorganisms of the genus Eschericia, hybrid DNA for use in their production and the use of the microorganisms in the preparation of glutathione
02/09/1983EP0071023A2 Method for producing L-isoleucine by fermentation
02/03/1983WO1983000346A1 Human calcitonin precursor polyprotein structural gene
02/01/1983US4371625 Vectors for the insertion therein of foreign DNA fragments, according to any translation phase
02/01/1983US4371615 Escherichia, mutants, cultures
02/01/1983US4371614 E.Coli bacteria carrying recombinant plasmids and their use in the fermentative production of L-tryptophan
01/1983
01/26/1983EP0070685A2 Homogeneous nucleic acid hybridization diagnostics by non-radiative energy transfer
01/26/1983EP0070675A1 Human calcitonin precursor polyprotein structural gene
01/26/1983EP0070632A2 Recombinant plasmids encoded for human preproinsulin and their use in producing human insulin
01/26/1983EP0070522A2 Plasmid p SVH 1 and its use
01/25/1983US4370417 Recombinant deoxyribonucleic acid which codes for plasminogen activator
01/25/1983US4370242 Device for and a method to separate orientable or deformable particles
01/20/1983WO1983000164A1 Plasmid for producing human insulin
01/18/1983CA1139693A1 Process for producing anthracycline glycosides
01/12/1983EP0069697A2 Preparation and use of plasmids containing the genes for biosynthesis of L-prolin
01/12/1983EP0069488A2 Method for the purification of urease and glutamate dehydrogenase
01/11/1983US4368269 Process for producing food proteins of fungal origin of from multicellular organisms fermentation apparatus and proteins so-produced
01/11/1983US4368263 Production of cephalosporins
01/05/1983EP0068867A2 Plasmids, micro-organisms, their preparation and use
01/05/1983EP0068790A2 Allele specific immunotherapeutic method and dosage form
01/05/1983EP0068763A2 Recombinant monoclonal antibodies
01/05/1983EP0068740A2 Recombinant DNA cloning vectors and the eukaryotic and prokaryotic transformants thereof
01/05/1983EP0068719A2 Deoxyribonucleic acids, their production and use
01/05/1983EP0068701A2 Proinsulin genes with modified C-chain
01/05/1983EP0068691A2 A process for the production of a polypeptide
01/05/1983EP0068647A2 Plasmids, plasmid hosts, and their preparation
01/05/1983EP0068646A1 Process for expressing the bovine growth hormone gene, and plasmid for use therein
01/05/1983EP0068375A2 Recombinant DNA techniques for the production of relaxin
12/1982
12/28/1982US4366246 Method for microbial polypeptide expression