Patents
Patents for C07H 19 - Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro derivatives thereof (20,008)
12/1999
12/29/1999CN1239964A Tetraphosphonate bicyclic trisanhydrides
12/29/1999CN1047781C Process for preparing 3'-azido-3'-thymine desoxyriboside and derivatives thereof
12/29/1999CA2335809A1 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives
12/29/1999CA2335758A1 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives
12/28/1999US6008400 Mixing trimethylorthoformate and an alcohol in a solvent to produce a reaction mixture and removing the solvent to yield orthoester reagent
12/28/1999US6008379 Useful as fluorescent dyes for labeling
12/28/1999US6008334 Base-protected nucleotide analogs with protected thiol groups
12/28/1999US6007992 Pyrimidine derivatives for labeled binding partners
12/23/1999DE19827777A1 New nikkomycin antibiotics with antifungal, fungicidal, miticidal and insecticidal activity produced by recombinant microorganisms
12/23/1999CA2332997A1 A process for the treatment of organophosphate poisoning
12/22/1999EP0684953A4 Adenosine kinase inhibitors comprising lyxofuranosyl derivatives.
12/21/1999US6005107 2-phosphonate-nucleotide analogues
12/21/1999US6005098 Nucleoside derivative which can be administered with 5-fluorouracil to enhance antitumor activity
12/21/1999US6005097 Reacting a hydroxyl protected lactone with a strong base, protecting hydroxyl with a silyl blocking group, reacting with a phenyl-seleno compound to produce at least 90% by weight of one stereoisomer; for efficient synthesis
12/21/1999US6005096 For oligonucleotides that are modified to enhance the binding affinity and to bear detectable labels; for diagnostic use
12/21/1999US6005087 Nuclease resistant oligonucleotides which are useful as therapeutics, diagnostics, and research reagents for various viral diseases
12/21/1999US6004995 Macrolide compound 0406
12/21/1999US6004958 Compounds and methods for therapeutic intervention in preventing diabetic complications and procedures for assessing a diabetic's risk of developing complications and determining the efficacy of therapeutic intervention
12/21/1999US6004939 Methods for modulation and inhibition of telomerase
12/16/1999WO1999064437A1 Nucleotide analogues with 3'-pro-fluorescent fluorophores in nucleic acid sequence analysis
12/16/1999WO1999064433A1 Method of preparing phosphoramidites
12/16/1999WO1999064431A2 Purines and pyrimidines linked to a quencher
12/16/1999WO1999064378A2 Directed combinatorial compound library and high throughput assays for screening same
12/16/1999WO1999064054A1 Multibinding inhibitors of topoisomerase
12/16/1999WO1999064051A1 Novel antibacterial compounds
12/16/1999WO1999064049A1 Novel antibacterial agents
12/16/1999WO1999064048A1 Inhibitors of hiv reverse transcriptase
12/16/1999WO1999064047A1 Novel antiviral compounds
12/16/1999WO1999064037A1 Novel therapeutic agents that modulate enzymatic processes
12/16/1999WO1999064033A1 Phosphodiesterase-v modulator drugs and their uses
12/16/1999WO1999064032A1 Combinatorial synthesis of multibinding libraries
12/16/1999WO1999063994A1 MULTIBINDING INHIBITORS OF HMG-CoA REDUCTASE
12/16/1999WO1999063988A1 Inhibitors of nitric oxide synthase
12/16/1999WO1999063940A2 INHIBITORS OF H+K+-ATPase
12/16/1999WO1999063939A2 Multibinding inhibitors of cyclooxygenase-2
12/16/1999WO1999063937A2 Multivalent macrolide antibiotics
12/16/1999WO1999063929A2 Multibinding inhibitors of microsomal triglyceride transferase protein
12/16/1999CA2334610A1 Purines and pyrimidines linked to a quencher
12/16/1999CA2334338A1 Directed combinatorial compound library and high throughput assays for screening same
12/16/1999CA2321274A1 Novel antiviral compounds
12/16/1999CA2321190A1 Novel therapeutic agents that modulate enzymatic processes
12/16/1999CA2321166A1 Multibinding inhibitors of topoisomerase
12/16/1999CA2321162A1 Novel antibacterial compounds
12/16/1999CA2320290A1 Multibinding inhibitors of cyclooxygenase-2
12/16/1999CA2320241A1 Multivalent macrolide antibiotics
12/16/1999CA2319761A1 Multibinding inhibitors of hmg-coa reductase
12/16/1999CA2319495A1 Multibinding inhibitors of microsomal triglyceride transferase protein
12/16/1999CA2319477A1 Inhibitors of h+k+-atpase
12/16/1999CA2319474A1 Inhibitors of nitric oxide synthase
12/16/1999CA2319120A1 Phosphodiesterase-v modulator drugs and their uses
12/16/1999CA2318547A1 Combinatorial synthesis of multibinding libraries
12/16/1999CA2316999A1 Inhibitors of hiv reverse transcriptase
12/15/1999EP0963997A1 Novel nucleotide analogues
12/15/1999EP0725782B1 A 1 adenosine receptor agonists and antiagonists
12/15/1999EP0714400B1 THERMODYNAMICALLY STABLE CRYSTAL FORM OF 4"-DEOXY-4"-(EPI)-METHYLAMINO AVERMECTIN B1a/B1b BENZOIC ACID SALT AND PROCESSES FOR ITS PREPARATION
12/14/1999US6002003 Cyanine dye activating group with improved coupling selectivity
12/14/1999US6001998 Macrocyclic lactone compounds and their production process
12/14/1999US6001994 Forming the lactone chemical intermediate 2-deoxy-2,2-difluoro-d-erythro-pentafuranose-1-ulose-3,5-dibenzoate in an efficient process without the use of a catalyst or silyl containing compound
12/14/1999US6001988 High affinity nucleic acid ligands to lectins
12/14/1999US6001966 Reacting n-terminal protected amino acid with peptide starting material forming a peptide product, partitioning from unreacted material and reagents based on presence of n-terminal blocking/anchoring group
12/14/1999US6001841 Cyclobutyl oligonucleotide surrogates
12/14/1999US6001577 Systematic evolution of ligands by exponential enrichment: photoselection of nucleic acid ligands and solution selex
12/14/1999CA2113065C Process for preparing optically active nucleosides from chiral cyclobutanones
12/09/1999WO1999062921A1 Antiviral phosphorus derivatives of 4'-thio-5-ethyl-2'-deoxyuridine
12/09/1999WO1999051617A3 FORM VI 5,6-DICHLORO-2-(ISOPROPYLAMINO)-1-(β-L-RIBOFURANOSYL)-1H-BENZIMIDAZOLE
12/08/1999EP0961775A2 Purine l-nucleosides, analogs and uses thereof
12/08/1999CN1238012A Stabilized aqueous nucleoside triphosphate solution
12/08/1999CN1047177C Process for preparing 1-(2'-deoxy-2',2'-difluoro-D-ribofuranosyl)-4-aminopyrimidin-2-one hydrochloride
12/07/1999US5998605 Antiviral benzimidazole nucleoside analogues and method for their preparation
12/07/1999US5998603 4'-desmethyl nucleoside analogs, and oligomers thereof
12/07/1999US5998594 Self-assembling, chromogenic receptors for the recognition of medically important substrates and their method of use
12/07/1999US5998388 Adenosine derivatives
12/07/1999US5998387 Method for using A1 adenosine receptor agonists
12/07/1999US5998386 Pharmaceutical compositions and method of using same for the treatment of failing myocardial tissue
12/07/1999US5998203 Enzymatic nucleic acids containing 5'-and/or 3'-cap structures
12/07/1999CA2128512C Homocysteine assay
12/02/1999WO1999061033A1 Bifunctional molecules for binding and regulating e-selectins and methods detecting same
12/02/1999WO1999061012A2 Therapeutic dinucleotide and derivatives
12/02/1999WO1999060855A1 Novel nucleosides having bicyclic sugar moiety
12/02/1999WO1999002544A8 Compounds having energy transfer function and method for dna base sequencing by using the same
12/02/1999CA2333380A1 Novel nucleosides having bicyclic sugar moiety
12/02/1999CA2332540A1 Therapeutic dinucleotide and derivatives
12/01/1999CN1237169A Tricyclic compounds useful for inhibition of G-protein function and treatment of proliferative diseases
12/01/1999CN1236616A Application of benzimidazole derivatives in preparing medicine
11/1999
11/30/1999US5994629 Positive selection
11/30/1999US5994321 Antiviral guanine analogs
11/30/1999US5994313 Regulated apoptosis
11/25/1999WO1999050438A3 Chromogenic indole derivatives
11/25/1999WO1999036429A3 Nucleobase oligomers
11/24/1999EP0495091B1 Aica riboside analogs
11/24/1999CN1236318A Method for treating bronchitis with uridine triphosphates and related compounds
11/23/1999US5990303 Reacting 7-deaza-2-deoxy guanosine with a phosphorylating agent to form nucleotide; used as guanosine nucleotide analogues for sequence determination; compounds are stable and nonaggregating
11/23/1999US5990300 Reacting nucleoside having unprotected 3' hydroxy group with nucleoside 5'-triphosphate having 3' position protected with removable blocking moiety, in presence of enzyme which catalyzes formation of 5' to 3' phosphodiester linkage
11/23/1999US5990094 Serotonin n-acetyltransferase inhibitors which can serve as biological tools that help reveal biological functions for melatonin and pineal serotonin in vivo; acetyl-coa n-acetyl tryptamine derivatives of given structure
11/23/1999US5990093 Treating hepatitis b virus (hbv) infections by administering a 5'-phospholipid prodrug of beta-l-2',3'-dideoxyadenosine 5'-monophosphate of given structure optionally with other anti-hbv agents, such as carbovir or 3tc
11/17/1999EP0956025A1 Method for immunosuppressing
11/17/1999EP0738273B1 Monohydrate of (e)-2'-deoxy-2'-(fluoromethylene)cytidine
11/17/1999CN1235594A Methods and compositions for lipidization of hydrophilic molecules
11/16/1999US5986086 A compound conatining cyanine dye, linker and nucleoside or nucleotide
11/16/1999US5986084 Nucleoside with triple substituted silyloxymethyl group as a protection group on the 2' oxygen; protection groups are not subject to isomerization and give higher coupling yields