Patents
Patents for C07H 19 - Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro derivatives thereof (20,008)
10/1998
10/27/1998US5827831 Lipid nucleotide analog prodrugs for oral administration
10/27/1998US5827819 Pharmaceutical composition comprising a psychotropic, neurotropic or neurological drug, a polar lipid carrier, two linker functional groups and a spacer; facilitates entry of drugs into cells and tissues
10/27/1998US5827727 Enzymatic stereospecific hydrolysis of 5-o-acylated nucleoside by an esterase, lipase, or subtilisin
10/27/1998US5827660 Fluorescent spectrum analysis of biological cell, dna, rna, proteins, nucleotic acids; digitized image
10/27/1998US5827645 Homocysteine assay
10/27/1998CA1340104C 23-deoxy derivatives of ll-f28249 compounds
10/21/1998EP0872237A1 Method and compositions for the synthesis of BCH-189 and related compounds
10/21/1998EP0871639A1 Novel orthosomycins from micromonospora carbonacea
10/21/1998EP0871620A1 Biocatalytic methods for synthesizing and identifying biologically active compounds
10/21/1998EP0766692B1 Guanylic acid derivatives and their use as drugs
10/20/1998US5824796 Cross-linking oligonucleotides
10/20/1998US5824793 Solid phase synthesis of oligonucleotide N3'-P5' phosphoramidates
10/20/1998US5824657 Anticarcinogenic agents, skin disorders and psoriasis
10/15/1998WO1998045310A1 Substituted propargylethoxyamido nucleosides
10/15/1998WO1998045309A1 Novel phosphate compounds and their use as medicaments
10/14/1998EP0869953A1 Nucleoside derivatives and process for preparing thereof
10/14/1998EP0804446A4 Method and composition for stabilization of labelled nucleoside triphosphates
10/14/1998CN1196059A Therapeutic compounds
10/13/1998US5821357 Reacting alpha-anomer enriched 2,2-difluorocarbohydrate with at least two molar equivalents of metal derivative of nucleobase in low freezing inert solvent
10/13/1998US5821356 Propargylethoxyamino nucleotides
10/13/1998US5821236 Tumor treatment with arabinofuranosyl purine derivatives
10/08/1998WO1998043992A1 Cyclic adenosine diphosphate ribose analogues
10/08/1998WO1998043991A1 Tricyclic base analogues
10/08/1998WO1998043651A1 Mur d inhibiting compounds, compositions containing such compounds and methods of use
10/07/1998CN1195353A New inhibitors of platelet aggregation
10/07/1998CN1040116C Liponucleotide compounds, pharmaceutical composition and its use
10/07/1998CN1040115C 5-methyluridine process for large-scale preparation of 2,3-didehydro-3-deoxythymidine (d4T)
10/07/1998CN1040114C Stereoselective glycosylation process
10/07/1998CN1040113C Intermediate for antiparasitic medicine-doramectin and its preparing process
10/06/1998US5817799 2'-Fluorofuranosyl derivatives and methods for preparing 2'-fluoropyrimidine and 2'-fluoropurine nucleosides
10/06/1998US5817786 Single-stranded labelled oligonucleotides of preselected sequences
10/06/1998US5817785 Methods of producing nucleic acid ligands
10/06/1998US5817781 Modified internucleoside linkages (II)
10/06/1998US5817667 Compounds and methods for the treatment of cancer
10/06/1998US5817664 Uracil reductase inactivators
10/06/1998US5817641 Treatment of enterotoxigenic diarrhea with 2-substituted adenosine derivatives
10/06/1998US5817640 Acadesine
10/06/1998US5817638 Antiviral liponucleosides: treatment of hepatitis B
10/01/1998WO1998042351A1 Difluoronucleoside phosphonic acids and derivatives thereof
10/01/1998CA2284263A1 Difluoronucleoside phosphonic acids and derivatives thereof
09/1998
09/30/1998EP0866796A1 Improvements in or relating to mutagenesis of nucleic acids
09/29/1998US5814639 Treating aids
09/24/1998WO1998041531A2 Solvent for biopolymer synthesis, solvent microdroplets and methods of use
09/24/1998WO1998041215A1 Aminoacyl sulfamides for the treatment of hyperproliferative disorders
09/24/1998CA2284211A1 Solvent for biopolymer synthesis, solvent microdroplets and methods of use
09/23/1998EP0866070A1 Derivatives of 7 deaza 2' deoxy guanosine 5' triphosphate, preparation and use thereof
09/23/1998EP0693077B1 Antiviral compounds
09/22/1998USRE35904 Method and probes for detecting nucleoside transporter and method for producing the probes
09/22/1998US5811539 Dissolving the dried protein-free cell extract or enzymic reaction mixture in an alcohol and an aqueous solution of an ammonium salt; mixing with silica gel and chromatographing
09/22/1998US5811534 Purine-based compounds for inclusion into oligonucleotides
09/22/1998US5811533 High-affinity oligonucleotide ligands to vascular endothelial growth factor (VEGF)
09/22/1998US5811408 Antitumor and anticarcinogenic agent; introducing sulfonyl group on hydroxy group of tetrahydrofuran ring, hydrolysis, blocking, oxidation, witting reaction, deprotection and phosphorylation
09/16/1998EP0863910A1 Method for solution phase synthesis of oligonucleotides
09/16/1998CN1193021A Intermediate compound for synthesizing nucleoside derivative
09/15/1998US5808049 Antitumor
09/15/1998US5808048 Process for preparing 1-(2'-deoxy-2',2'-difluoro-D-ribofuranosyl)-4-aminopyrimidin-2-one) hydrochloride
09/15/1998US5808047 Blocking; hydrolysis; oxidation
09/15/1998US5808045 Compositions for enzyme catalyzed template-independent creation of phosphodiester bonds using protected nucleotides
09/15/1998US5808043 Composition for stabilization of labelled nucleoside triphosphates and methods for using same
09/15/1998US5808040 L-nucleosides incorporated into polymeric structure for stabilization of oligonucleotides
09/15/1998US5808039 2'-OMe CAC phosphoramidite and methods for preparation and use thereof
09/15/1998US5808035 Protected nucleoside and method for its synthesis
09/15/1998US5808027 N-2 substituted purines in oligonucleotides
09/15/1998US5808023 Modified oligonucleotides
09/15/1998CA2122815C 2'-deoxy-2'-fluorocoformycin and stereoisomers thereof
09/11/1998WO1998039352A1 Novel bicyclonucleoside and oligonucleotide analogues
09/11/1998WO1998039349A1 Protecting group for synthesizing oligonucleotide analogs
09/11/1998WO1998039348A1 Photocleavable protecting groups and methods for their use
09/09/1998EP0863148A1 Compounds derived from adenosine, use of such compound as a medicament, method for synthesizing such a compound and intermediates thereof
09/09/1998EP0513200B1 Method and compositions for the synthesis of bch-189 and related compounds
09/09/1998CN1039708C Method for prepn. of diiodo-compound
09/08/1998US5804564 Antitumor indolopyrrolocarbazole derivatives
09/08/1998CA1340032C Lucleoside derivatives
09/03/1998WO1998038202A1 Antiviral phosphonate prodrugs of nucleosides and nucleoside analogues
09/03/1998WO1998038201A1 Process for the preparation of ivermectin
09/03/1998WO1998038197A1 Protected aminosugars
09/03/1998WO1998028317A3 Synthesis of nucleosides and polynucleotides
09/03/1998WO1998008855A3 N6 heterocyclic substituted adenosine derivatives
09/03/1998CA2282789A1 Protected aminosugars
09/02/1998EP0861260A1 Improved method and agents for inhibiting protein aging
09/02/1998CN1192149A Methods of reducing toxicity of chemotherapeutic and antiviral agents with acylated pyrimidine nucleosides
09/02/1998CN1192138A Acyclovir derivatives for topical use
09/02/1998CN1039645C 1,3-(substd. thio) acetoxy Melbamycinum derivatives, their preparation method, and use in agricultural chemistry
09/01/1998US5801159 Method and composition for inhibiting cellular irreversible changes due to stress
09/01/1998US5801155 Covalently linked oligonucleotide minor grove binder conjugates
09/01/1998US5801144 Use of a compound for the manufacture of a medicament for the treatment of HIV infection
09/01/1998US5801006 Use of NADPH and NADH analogs in the measurement of enzyme activities and metabolites
09/01/1998US5800992 Method of detecting nucleic acids
09/01/1998CA1340022C Alkynylamino-nucleotides
08/1998
08/26/1998EP0686641B1 2'-deoxy-5-fluorouridine derivative, pharmaceutically acceptable salt thereof, process for producing the same, and antitumor drug
08/26/1998EP0664708B1 Method of treating cancer by conjunctive therapy with 2'-halomethylidene derivatives and an s-phase or m-phase specific antineoplastic agent
08/26/1998CN1191553A Method of detecting lung disease
08/25/1998US5798340 Antitumor/antineoplastic actiity, viricides; broad spectrum microbiocides; thiophosphonates hydrolyzable in vivo; oral administration; bioavailability; nontoxic; potency
08/25/1998US5798276 Reactive derivatives of sulforhodamine 101 with enhanced hydrolytic stability
08/25/1998US5798210 Derivatives utilizable in nucleic acid sequencing
08/25/1998CA2147758C Antiparasitic 6,8a-seco deoxyavermectin derivatives
08/25/1998CA2087543C Heterocyclic compounds
08/20/1998WO1998035980A1 High affinity nucleic acid ligands of cd4
08/20/1998WO1998035978A1 Aminooxy-modified oligonucleotides
08/20/1998WO1998035977A1 Benzimidazole derivatives