Patents
Patents for C07H 19 - Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro derivatives thereof (20,008)
06/1998
06/30/1998CA1339935C Dna and rna molecules stabilized by modifications of the 3'-terminal phosphodiester linkage and their use as nucleic acid probes and as therapeutic agents to block the expression of specifically targeted genes
06/25/1998WO1998026786A1 Caged membrane-permeant inositol phosphates
06/24/1998EP0848717A1 Process for the preparation of imidazolyl macrolide immunosuppressants
06/24/1998EP0759927B1 Pteridine nucleotide analogs as fluorescent dna probes
06/24/1998EP0637314B1 N-acylated 2'-deoxycytidines useful in oligonucleotide synthesis
06/23/1998US5770725 Uses novel group, characterized by the presence of-s-s-and/or s-c=z (z=o or s) enzyme labile bonds which leads, after enzymatic activation, to the formation of unstable intermediate which releases monophosphate or monophosphonate
06/23/1998US5770716 Chain terminating and chain extending nucleotides, primer extension reactions, dna sequencing, polymerase chain reaction
06/23/1998US5770715 Hammerhead-like nucleic acid analogues and their synthesis
06/23/1998US5770713 Phosphorothioate triester oligonucleotides and method of preparation
06/23/1998US5770607 Aqueous liquid composition for external use
06/23/1998US5770582 Mixture of deoxycytidine and deoxyguanosine in a carrier
06/23/1998US5770571 Method and agents for inhibiting protein aging
06/23/1998US5770456 Cyclic nucleic acid and polypeptide arrays
06/23/1998US5770407 Process for preparing nucleotide inhibitors of glycosyltransferases
06/23/1998US5770358 Tagged synthetic oligomer libraries
06/18/1998WO1998025940A1 Inhibitors of glycosyltransferases
06/18/1998WO1998018430A3 P2y receptor antagonists
06/17/1998CN1185110A Synergistic combination of zidovudine
06/17/1998CN1038750C Deoxy hexose monosaccharides having a saturated nitrogen-contg. heterocyclic
06/16/1998US5767378 Genetic engineering
06/16/1998US5767270 Protecting exocyclic amino groups
06/16/1998US5767264 Oligodeoxynucleotides containing 5-alkyl, 5-(1-alkenyl)- and 5-(1-alkynl) pyrimidines
06/16/1998US5767263 Base-modified enzymatic nucleic acid
06/16/1998US5767097 Specific modulation of Th1/Th2 cytokine expression by ribavirin in activated T-lymphocytes
06/16/1998US5766853 Method for identification of high affinity nucleic acid ligands to selectins
06/16/1998US5766850 Human β2 integrin α subunit
06/16/1998CA2132457C Fluorosugar derivatives of macrolides
06/11/1998WO1998016186A3 Monocyclic l-nucleosides, analogs and uses thereof
06/10/1998EP0827501A4 Non-nucleosidic coumarin derivatives as polynucleotide-cross-linking agents
06/10/1998CN1184430A Compositions of interleukin and pyrimidine nucleosides
06/09/1998US5763599 For light-controlled synthesis of oligonucleotides on dna chip
06/09/1998US5763597 Orally active adenosine kinase inhibitors
06/09/1998US5763596 C-4' modified adenosine kinase inhibitors
06/09/1998US5763595 Nucleic acid ligands which bind covalently with protein
06/09/1998US5763594 3' protected nucleotides for enzyme catalyzed template-independent creation of phosphodiester bonds
06/09/1998US5763588 Pyrimidine derivatives for labeled binding partners
06/09/1998US5763566 Systematic evolution of ligands by exponential enrichment: tissue SELEX
06/09/1998US5763447 Method of preventing or treating pneumonia in immobilized patients with uridine triphosphates and related compounds
06/09/1998US5763419 Treatment of malignant tumors with 8-chloroadenosine 3',5'-cyclic monophasphate
06/09/1998US5763418 Nucleotide antitumor agents
06/09/1998US5763208 Oligonucleotides and their analogs capable of passive cell membrane permeation
06/09/1998US5763177 Systematic evolution of ligands by exponential enrichment: photoselection of nucleic acid ligands and solution selex
06/09/1998US5763173 Nucleic acid ligand inhibitors to DNA polymerases
06/09/1998US5763167 Applications of fluorescent N-nucleosides and fluorescent structural analogs of N-nucleosides
06/09/1998CA2139506C A facile enzymatic synthesis of galactosyl-beta-1, 3 glycals
06/04/1998WO1998017325A3 Covalent polar lipid conjugates for targeting
06/03/1998EP0845001A1 5'-substituted-ribofuranosyl benzimidazoles as antiviral agents
06/03/1998CN1038591C Processes for diastereoselective synthesis of nucleosides
06/02/1998US5760210 Reacting siloxane-protected cytidine derivative with phosphonate ylid, then with stannylating reagent, then with protolysis agent, deprotecting
06/02/1998US5760209 Protecting group for synthesizing oligonucleotide analogs
06/02/1998US5760208 Condensation; acylation
06/02/1998US5760202 Treating 2,2'-anhydropyrimidine nucleoside with alcohol and lewis acid
06/02/1998US5760042 Inhibitor of phosphodiesterases
06/02/1998US5760013 Thymidylate analogs and the use thereof
06/02/1998US5759993 Modified sialyl Lewisx compounds
05/1998
05/28/1998WO1998022489A1 Novel nucleotide analogues
05/28/1998WO1998016184A3 Purine l-nucleosides, analogs and uses thereof
05/27/1998EP0843684A2 Universal solid supports and methods for their use
05/27/1998EP0646125B1 1,5-anhydrohexitol nucleoside analogues and pharmaceutical use thereof
05/26/1998US5756775 Process to make α,α-difluoro-β-hydroxyl thiol esters
05/26/1998US5756711 Viricides
05/26/1998US5756707 Method of making 2'-O-alkyl pyrimidine ribonucleosides
05/26/1998US5756706 Chemical intermediates
05/26/1998US5756704 Nucleosides and nucleoside derivatives containing enzymatically cleavable protecting groups
05/26/1998US5756486 Cyclized nucleotide; viricide
05/26/1998US5756480 Administering reductase inhibitor from 3-oxo-4-oxa and 4-thiasteroids having a 1,2-double bond and the pyridine-nucleotide cofactor of nadph
05/26/1998US5756479 Flavin adenine dinucleotide analogue inhibitors of monoamine oxidase
05/26/1998US5756478 Treating cancer while reducing toxicity associated with the administration of conventional ''D'' nucleoside drugs such as AZT, by coadministering ''L'' nucleoside compounds such as Beta-L-2',3'-dideoxy-2',3'-didehydrocytidine; AIDS
05/26/1998US5756477 Treatment of aids with complex of poly (A). poly (U)
05/26/1998US5756287 Complexing
05/26/1998US5756116 Nucleoside phosphate therapy for viral infection
05/22/1998WO1998021362A2 Stabilized aqueous nucleoside triphosphate solution
05/22/1998WO1998021223A1 Nucleosides
05/22/1998WO1998001555A3 Truncated soluble tumor necrosis factor type-i and type-ii receptors
05/22/1998CA2271135A1 Nucleosides
05/20/1998EP0842942A1 D-pentofuranose derivatives and process for the preparation thereof
05/20/1998EP0842185A1 Improved therapeutic agents
05/20/1998EP0842181A1 Membrane-permeant second messengers
05/20/1998EP0841907A1 Use of agonists or antagonists of p 2? purinoceptors for the prevention of glutamate-evoked cytotoxicity
05/20/1998EP0841900A1 Method of detecting lung disease
05/20/1998EP0686150B1 Process for the preparation of C-nucleosides and C-nucleoside analogues, new C-nucleosides and C-nucleoside analogues and their use
05/20/1998DE19647055A1 Stabilisierte wässrige Nukleosidtriphosphat-Lösungen A stabilized aqueous solutions nucleoside triphosphate
05/20/1998CN1182430A Carbohydrate conjugated bio-active compounds
05/19/1998US5753788 Photolabile nucleoside protecting groups
05/19/1998US5753213 Pharmaceutical compositions containing 5'-deoxy-5'-methylthioadenosine s-adenosylmethionine and their salts for reducing seborrhea
05/14/1998WO1998020017A1 Modified nucleoside-5'-triphosphates
05/14/1998WO1998019685A1 Method of treating bronchitis with uridine triphosphates and related compounds
05/14/1998WO1998003182A3 Use of uridine triphosphates and related compounds for the prevention and treatment of pneumonia in immobilized patients
05/13/1998EP0841344A1 1-(2-deoxy-2-fluoro-4-thio-beta-d-arabinofuranosyl)cytosines
05/13/1998EP0840742A1 Systematic evolution of ligands by exponential enrichment: chemi-selex
05/13/1998EP0840740A1 New inhibitors of platelet aggregation
05/12/1998US5750735 Chemical intermediates for antibiotics
05/12/1998US5750692 Alkylating cyano-1-(3,5-di-o-p-toluoyl-beta-d-pentose)imidazole in base, ammonolyating, cyclizing
05/12/1998US5750676 Process for preparing nucleosides with unprotected sugars
05/12/1998US5750675 2'-"up" fluorinated 2'-deoxy-arabinofuranosylpurines
05/12/1998US5750674 Methods and compounds for the stereoselective enrichment of oligonucleotide diastereomers and oligonucleotides thereby produced
05/12/1998US5750673 Nucleosides with 2'-O-modifications
05/12/1998US5750669 Nuclease-stable antiviral agents which can suppress synthesis of antigens and gene expression of proteins
05/12/1998US5750666 Polynucleotide phosphorodithioate compounds
05/12/1998US5750512 For treatment of parkinson's and alzheimer's disease or mental depression