Patents
Patents for C07H 19 - Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro derivatives thereof (20,008)
05/1999
05/14/1999WO1999010365A3 5',5'-linked oligomers having anti-thrombin activity
05/12/1999EP0914431A2 Truncated soluble tumor necrosis factor type-i and type-ii receptors
05/12/1999EP0735888A4 Purine compositions and methods for administration
05/11/1999US5902880 RNA polymerase III-based expression of therapeutic RNAs
05/11/1999US5902879 Methoxyoxalamido and succinimido precursors for nucleophilic addition to nucleosides, nucleotides and oligonucleotides
05/11/1999US5902878 Modified phosphoramidite process for the production of modified nucleic acids
05/11/1999US5902794 Camp derivatives, one is selective for site 1 of a type ii camp dependent protein kinase and the other is selective for site 2 of type i or ii camp dependent protein kinase, having a synergistic inhibitory effect on cancer cell growth
05/11/1999US5902723 Selectively removing a nucleotide by cleavage at terminal ends with catalytic antibodies; identifying excision site and repeating process; for concurrent parallel sequence analysis
05/11/1999US5902567 Administering to lung by inhalation physiologically acceptable salt to hydrate secretions, concurrently administering uridine triphosphate or derivative to stimulate secretion, collecting expectorated mucus sample
05/06/1999WO1999021872A1 Nucleotide compounds and method of synthesizing oligonucleotides
05/06/1999WO1999009041A3 Solution phase synthesis of oligonucleotides
05/06/1999EP0912613A1 Synthetic polysaccharides, preparation method therefor and pharmaceutical compositions containing same
05/06/1999EP0912592A1 Phosphotriester oligonucleotides, amidites and method of preparation
05/06/1999EP0912520A1 Compounds having antihypertensive, cardioprotective, anti-ischemic and antilipolytic properties
05/06/1999EP0570519B1 Oxypurine nucleosides and their congeners, and acyl derivatives thereof, for improvement of hematopoiesis
05/05/1999CN1043231C Monohydrate of (E)-alpha-deoxy-alpha-(fluoro-methylene) cytidine
05/04/1999US5900407 Method of treating dry eye disease with uridine triphosphates and related compounds
05/04/1999US5900237 Catalytic antibodies which hydrolyze primary amides and methods for eliciting such antibodies
05/04/1999CA2078129C O6-benzylated guanine, guanosine and 2'- deoxyguanosine compounds possessing o6-alkylguanine-dna alkyltransferase depleting activity
04/1999
04/29/1999WO1999020791A1 Method for suppressing multiple drug resistance in cancer cells
04/29/1999WO1999020789A1 Analyte assay using particulate labels
04/29/1999CA2719432A1 Analyte assay using particulate labels
04/29/1999CA2307342A1 Method for suppressing multiple drug resistance in cancer cells
04/28/1999EP0910634A2 ANTISENSE INHIBITORS OF VASCULAR ENDOTHELIAL GROWTH FACTOR (VEgF/VPF) EXPRESSION
04/28/1999CN1215057A Process for large-scale preparation of 2',3'-didehydro-2',3-dideoxynucleosides
04/27/1999CA2056823C Derivatives of 10,11,12,13-tetrahydrodesmycosin processes for preparation, and use thereof in pharmaceuticals
04/22/1999WO1999019338A1 Inhibitors of nucleoside metabolism
04/22/1999WO1999018798A1 Compositions and methods for the treatment of primary and metastatic neoplastic diseases using arsenic compounds
04/22/1999WO1998048849A9 Radionuclide associated with nucleotide polyphosphate as tumor imaging agents
04/22/1999CA2307208A1 Compositions and methods for the treatment of primary and metastatic neoplastic diseases using arsenic compounds
04/21/1999EP0909184A2 Targeted drug delivery using sulfonamide derivatives
04/21/1999EP0543889B1 Incorporation of selectably clevable sites into oligonucleotide chains and reagents therefor
04/20/1999CA2165806C Antiparasitic agents
04/20/1999CA2150841C Method for the preparation of magnesium hydride
04/15/1999WO1999018114A1 Novel nucleoside or nucleotide fluorescent conjugates, preparation method and uses
04/15/1999WO1999000399A9 Method of producing tiazofurin and other c-nucleosides
04/15/1999WO1998056761A3 Benzimidazole derivatives
04/15/1999CA2305811A1 Novel nucleoside or nucleotide fluorescent conjugates, preparation method and uses
04/14/1999CN1214049A Therapeutic compounds
04/14/1999CN1042939C Synthetic method of arabinosyladenosine
04/13/1999CA2173494C Process and antiparasitic intermediates for doramectin
04/08/1999WO1999016832A1 Aromatic-substituted xanthene dyes
04/07/1999EP0906917A2 Method for chemical synthesis of oligonucleotides
04/07/1999EP0906327A2 Intermediates for oligonucleotide synthesis
04/07/1999EP0741740B1 Method of preparing unsymmetrical phosphoric acid diesters and salts
04/06/1999US5892025 Method of resolution and antiviral activity of 1,3-oxathiolane nucleoside enantiomers
04/06/1999US5892024 Bifunctional nucleosides, oligomers thereof, and methods of making and using the same
04/06/1999US5892007 Protecting at least one group in at least one compound in a mixture of compounds to be separated with a multiple fused ring protecting group, passing the mixture through a chamber filled with a reverse phase silica gel or polystyrene material
04/06/1999US5891684 Base-modified enzymatic nucleic acid
04/06/1999US5891683 Having enzymatic activity to cleave a target rna molecule, wherein said enzymatic nucleic acid molecule comprises an abasic moiety in a single-stranded region of said enzymatic nucleic acid molecule.
04/01/1999WO1999015542A2 Linker nucleoside, and production and use of the same
04/01/1999WO1999015541A2 Use of a pentopyranosyl nucleoside for producing an electronic component, and conjugates of said pentopyranosyl nucleoside
04/01/1999WO1999015540A2 Method for producing a pentopyranosyl nucleoside
04/01/1999WO1999015539A2 Pentopyranosyl nucleoside, and production and use of the same
04/01/1999WO1999002532A3 Partially hydrogenated polycyclic compounds
04/01/1999CA2303784A1 Use of a pentopyranosylnucleoside for the production of an electronic component, and conjugates thereof
04/01/1999CA2303527A1 Linker nucleoside, its preparation and use
04/01/1999CA2302414A1 Process for the preparation of a pentopyranosylnucleoside
03/1999
03/31/1999EP0904275A1 Preparation of phosphorothioate oligomers
03/31/1999EP0625158B1 Therapeutic nucleosides of the 2',3'-dideoxy-3'-fluoro-purine series
03/30/1999US5889178 N-(2,2-diphenylethyl)-derivatives
03/30/1999US5889165 Photolabile nucleoside protecting groups
03/30/1999US5889136 Phosphoramidite oligonucleotide biosynthesis
03/30/1999US5888829 Photolabile caged ionophores and method of using in a membrane separation process
03/30/1999US5888532 Treatment of alcoholism and related disorders with (nicotinamide-adenine dinucleotide) phosphate derivatives
03/30/1999CA2170608C 5-(1-fluoro-vinyl)-1h-pyrimidine-2,4-dione derivatives useful as antineoplastic agents
03/30/1999CA2168731C Antiparasitic agents
03/25/1999WO1999014226A2 Bi- and tri-cyclic nucleoside, nucleotide and oligonucleotide analogues
03/25/1999WO1999013721A1 Pharmaceutical compositions and methods for the treatment of failing myocardial tissue
03/25/1999DE19741738A1 Linker nucleoside(s) containing alkenyloxy or phthalimido-alkyl groups
03/25/1999DE19741715A1 New pentopyranosyl nucleoside compounds
03/25/1999CA2303299A1 Bi- and tri-cyclic nucleoside, nucleotide and oligonucleotide analogues
03/24/1999EP0902788A1 Nucleoside derivatives, and their use in oligonucleotide synthesis
03/24/1999EP0902779A2 Phosphate mimics
03/23/1999US5886179 Nucleotide analogs
03/23/1999US5886167 2'-deoxy-2'-epi-2'-fluorocoformycin
03/23/1999US5886162 Lipophilic diakylaminomethylene prodrug derivatives for the inhibition of replication of viruses
03/23/1999US5885972 L-pyranosyl nucleosides
03/23/1999US5885957 Treatment of HTLV-I infections
03/18/1999WO1999012951A1 Uses of nicotinamide adenine dinucleotide and its analogs for treatment of malignant and infectious diseases
03/18/1999CA2302687A1 Uses of nicotinamide adenine dinucleotide and its analogs for treatment of malignant and infectious diseases
03/17/1999EP0902034A2 Very large scale immobilized peptide synthesis
03/17/1999EP0901501A1 Nucleoside derivatives with photo-unstable protective groups
03/17/1999EP0901500A1 $i(IN SITU) PREPARATION OF NUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE IN SYNTHESIS OF OLIGONUCLEOTIDES
03/17/1999EP0901499A1 Adenosine derivatives
03/17/1999CN1211186A Method of treating otitis media with uridine triphosphates and related compounds
03/16/1999US5883237 Oligonucleotides having Rp and Sp linkages at predetermined locations
03/16/1999US5883080 Antiparastic auermectin derivatives
03/16/1999US5882901 Sialylating specified oligosaccharide with sialyltransferase, fucosylating with fucosyltransferase
03/16/1999CA2152819C New antiparasitic agents related to the milbemycins and avermectins
03/11/1999WO1999011274A1 Use of purine nucleosides for modulating the axonal outgrowth of central nervous system neurons
03/10/1999EP0900805A2 Incorporation of selectably cleavable and/or abasic sites into oligonucleotide chains and reagents therefor
03/10/1999EP0900220A1 3- and 3,8-substituted 1,10-phenanthrolines and their use in electron and energy transfer processes
03/10/1999EP0623137B1 Antiparasitic agents
03/10/1999CN1042430C N-alkyl-2-substituted ATP anologues, preparation and use thereof
03/10/1999CN1042429C 5-(1-fluoro-vinyl-1H-pyrimidine-2,4-dione derivatives, medicinal composition and preparation thereof
03/09/1999US5880294 Intermediates for substituted ribonucleoside antitumor agents
03/09/1999US5879938 Ribozyme with increased activity by substitution of modified nucleotide into substrate binding arm or catalytic core
03/09/1999US5879700 Treating herpes virus infections
03/04/1999WO1999010369A1 Compositions, kits, and methods for effecting adenine nucleotide modulation of dna mismatch recognition proteins